Nature March 2006 PMID 16541064

Folding DNA to create nanoscale shapes and patterns.

Paul W K Rothemund

Mentions

116
Peak: 4 in Nov 2020
across 6 sources since Mar 2019

Extended reach

72,341
potential audience

Total likes

24

Video views

1,599

Mentions per month

Mar 2019 – Mar 2025

Where it's discussed

  • News44 articles
  • Blogs35 articles
  • Facebook24 posts
  • X / Twitter10 posts
  • YouTube2 videos
  • Bluesky1 posts

AI synopsis

What people are saying

The discussions demonstrate high interest and a positive attitude toward Rothemund's pioneering work, with phrases like 'time to put the origami in our DNA Origami Reading Group' and references to the paper as 'seminal,' illustrating both admiration and recognition of its importance in nanotechnology. The tone and word choices reflect a sense of excitement and appreciation for the scientific advance.

AgreementModerate agreement

Most posts show enthusiasm for the significance of the research, referencing it as a foundational or innovative work in DNA nanotechnology.

InterestHigh interest

Discussions highlight curiosity and fascination with DNA origami, indicating high interest in the subject across the group.

EngagementModerate engagement

Comments include acknowledgments of the research’s implications and mentions of related projects, showing active engagement.

ImpactModerate impact

The tweets suggest recognition of the publication's potential for advancing nanofabrication and nanoengineering, implying moderate impact.

Abstract in brief

  • This text explains a method for creating complex two-dimensional shapes at the nanoscale by folding long single-stranded DNA molecules, using a combination of a scaffold strand and around 200 short staple strands that guide the shape formation.
  • The process involves designing a pattern that the DNA will fold into, with each staple strand acting as a 6nm pixel, allowing for precise and detailed shapes like words, images, or geometric figures such as squares and stars, with structures about 100nm wide.
  • The technique enables the construction of not only individual DNA nanostructures but also larger assemblies, including periodic lattices and complex molecular structures, moving towards more intricate nanofabrication comparable to top-down methods.]

Top posts

Most liked on X and Bluesky
Rafal Baker
@RafalBaker · X

Who says you can't have fun in the lab? These structures are made of multiple tiny single strands of DNA stapled together, with an avg diameter of ~100nm (~80,000x smaller than a common house-fly) Full article: Rothemund, P. Nature 440, 297–302 (2006). https://t.co/yeOPrSdPoi https://t.co/bp3t56qfiX

Nov 20, 2020 · 9 likes · 2 shares · 438 followers View post →
Ryan sikorski
@Ryansikorski10 · X

Dec 11, 2024 · 7 likes · 2 shares · 36,249 followers View post →
Kirti Prakash | PhD | FRMS
@kirtiprakash25 · X

Here are three that come to my mind: Optical Conformal Mapping by Leonhardt https://t.co/vFBJZTO9BH Folding DNA to create nanoscale shapes and patterns by Rothemund https://t.co/uigNpP6bTV Exploring complex networks by @stevenstrogatz https://t.co/r7OgfXQAxb

Mar 19, 2020 · 3 likes · 1,102 followers View post →
Molpigs
@molpigs.bsky.social · Bluesky

It's time to put the origami in our DNA Origami Reading Group! This week we're reading Rothemund's "Folding DNA to create nanoscale shapes and patterns" to understand this seminal paper in context! What did Rothemund know, and what did he intuit? Join us to discuss!

Mar 15, 2025 · 3 likes · 1 share View post →
Thamarasee Jeewandara
@Jeew333T · X

DNA origami - folding DNA to create nanoscale shapes and patterns. https://t.co/ixhSjrEC9G In #DNA nanotechnology, bottom-up fabrication explores the inherent properties of atoms and molecules to direct their self-organization and make relatively simple nanostructures.

Aug 8, 2023 · 1 like · 1,280 followers View post →
José Montaño
@Chemystified · X

We got DNA for origami (https://t.co/PGZYIkvl5c), DNA for building small machines that help orient protein for cryo-EM (https://t.co/UZOry2r6En), and now DNA for organelle-specific membrane voltmeters!: https://t.co/gj7fUuVhIH

Nov 4, 2020 · 1 like · 279 followers View post →

All mentions

Molpigs
@molpigs.bsky.social · Bluesky

It's time to put the origami in our DNA Origami Reading Group! This week we're reading Rothemund's "Folding DNA to create nanoscale shapes and patterns" to understand this seminal paper in context! What did Rothemund know, and what did he intuit? Join us to discuss!

Mar 15, 2025 · 3 likes · 1 share View post →
Neil Harrison
@NeilHar38005083 · X

RT @Ryansikorski10:

Dec 11, 2024 · 2 shares · 2,999 followers View post →
Sophie still fighting
@mariusknulst · X

RT @Ryansikorski10:

Dec 11, 2024 · 2 shares · 26,847 followers View post →
Ryan sikorski
@Ryansikorski10 · X

Dec 11, 2024 · 7 likes · 2 shares · 36,249 followers View post →
Thamarasee Jeewandara
@Jeew333T · X

DNA origami - folding DNA to create nanoscale shapes and patterns. https://t.co/ixhSjrEC9G In #DNA nanotechnology, bottom-up fabrication explores the inherent properties of atoms and molecules to direct their self-organization and make relatively simple nanostructures.

Aug 8, 2023 · 1 like · 1,280 followers View post →
Colin MacIntyre
@Colin_Science · X

RT @RafalBaker: Who says you can't have fun in the lab? These structures are made of multiple tiny single strands of DNA stapled together,…

Nov 27, 2020 · 2 shares · 155 followers View post →
Rajrishi Kumar
@RajrishiKumar9 · X

RT @RafalBaker: Who says you can't have fun in the lab? These structures are made of multiple tiny single strands of DNA stapled together,…

Nov 21, 2020 · 2 shares · 88 followers View post →
Rafal Baker
@RafalBaker · X

Who says you can't have fun in the lab? These structures are made of multiple tiny single strands of DNA stapled together, with an avg diameter of ~100nm (~80,000x smaller than a common house-fly) Full article: Rothemund, P. Nature 440, 297–302 (2006). https://t.co/yeOPrSdPoi https://t.co/bp3t56qfiX

Nov 20, 2020 · 9 likes · 2 shares · 438 followers View post →
José Montaño
@Chemystified · X

We got DNA for origami (https://t.co/PGZYIkvl5c), DNA for building small machines that help orient protein for cryo-EM (https://t.co/UZOry2r6En), and now DNA for organelle-specific membrane voltmeters!: https://t.co/gj7fUuVhIH

Nov 4, 2020 · 1 like · 279 followers View post →
Kirti Prakash | PhD | FRMS
@kirtiprakash25 · X

Here are three that come to my mind: Optical Conformal Mapping by Leonhardt https://t.co/vFBJZTO9BH Folding DNA to create nanoscale shapes and patterns by Rothemund https://t.co/uigNpP6bTV Exploring complex networks by @stevenstrogatz https://t.co/r7OgfXQAxb

Mar 19, 2020 · 3 likes · 1,102 followers View post →
Thamarasee Jeewandara
@Jeew333T · X

Folding DNA to create nanoscale shapes and patterns. - Rothemund PW https://t.co/0JZpczP3Ps 2006, #DNAorigami

Mar 23, 2019 · 1,280 followers View post →