April 2006 PMID 16596767

Final report of the safety assessment of niacinamide and niacin.

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Mentions

Peak: 1 in Dec 2021

across 4 sources since Dec 2021

Extended reach

512,812

potential audience

Total likes

11,850

Video views

506,366

Mentions per month

Dec 2021 – Nov 2025

Where it's discussed

X / Twitter4 posts
YouTube2 videos
Facebook2 posts
News2 articles

AI synopsis

What people are saying

The collective reactions reflect cautious curiosity, with references to prior studies like those by Wohlrab and the safety assessment report, yet many users dismiss certain claims or show limited engagement, indicated by phrases like 'I'll pass!!!!' and minimal elaboration. The tone suggests a neutral or mildly skeptical attitude, with interest centered around safety and efficacy concerns.

AgreementNeither agree nor disagree

The discussion seems neutral, with few expressing strong opinions either for or against the publication's safety conclusions.

InterestModerate interest

Participants show some curiosity, especially in referencing related studies and historical data, but overall engagement remains limited.

EngagementLow engagement

Most comments are brief or dismissive, with little deep analysis or extensive discussion of methodologies.

ImpactNeutral impact

The discussions are somewhat academic and don't appear to influence broader opinions or behaviors significantly.

Abstract in brief

Niacinamide (nicotinamide) and Niacin (nicotinic acid) are chemical compounds used mainly as conditioning agents in hair and skin cosmetics, with Niacinamide appearing in about 30 different products.
Both ingredients are approved for cosmetic use in Japan and the EU, are recognized as safe for food and supplements, and can be used in medical treatments for conditions like high cholesterol (Niacinamide) and pellagra (Niacin).
Safety studies show that while Niacinamide is somewhat more toxic than Niacin in acute toxicity tests, both are generally considered to have low toxicity, with minimal irritation or allergic responses observed in animal testing.

Read the full abstract

All mentions

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Dermisphere Dra. Leire Barrutia · Jun 16, 2022 443,109 views

Niacinamide in Skincare: Effects, Myths, and Scientific Insights

Niacinamide is a popular ingredient in many skincare products. This video explores its effectiveness in reducing skin pigmentation by inhibiting melanosome transfer, backed by scientific research and clinical trials…

Incipedia Skincare · Oct 18, 2023 63,257 views

PureBlood4Life:)

@broski111213 · X

@celestialbe1ng "Niacinamide can moderate the induction of tumors by established carcinogens" I'll pass!!!! https://t.co/v9ZqSNMVno

Nov 16, 2025 · 3 followers View post →

เภสัชจ๋า สิวลาก่อน

@PhSongAcne · X

[Ref] https://t.co/Z2TbogvKAc

Apr 28, 2025 · 5 followers View post →

STARINC

@starincofficial · X

Jul 2, 2023 · 519 followers View post →

Stefan

@skinchemically · X

Sumber: 1. https://t.co/tU6s8wbz7Z 2. https://t.co/XRVD96eaEm

Dec 23, 2021 · 2 likes · 5,920 followers View post →