PubHawk
July 2006 PMID 16844493

Cholesterol gallstone disease.

Piero Portincasa, Antonio Moschetta, Giuseppe Palasciano

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Mentions

27
Peak: 16 in Oct 2024
across 3 sources since Jul 2020

Extended reach

41,896
potential audience

Total likes

256

Video views

14,529

Mentions per month

Jul 2020 – May 2025

Where it's discussed

  • YouTube16 videos
  • X / Twitter9 posts
  • Blogs2 articles

AI synopsis

What people are saying

The collective discussions show considerable interest, exemplified by references to studies on biliary immunoglobulins, cholesterol nucleation factors, and liver proteins like NPC1L1, with tone ranging from curiosity to cautious interpretation, emphasizing molecular mechanisms and potential therapeutic targets.

AgreementNeither agree nor disagree

Most discussions recognize the relevance of biochemical and immunological factors in understanding gallstone disease, but some show skepticism about the direct implications of specific proteins or mechanisms.

InterestHigh interest

The discussions demonstrate high interest, with multiple mentions of factors like biliary immunoglobulins, cholesterol saturation, and genetic mechanisms, indicating engagement with complex scientific content.

EngagementModerate engagement

Posts reference specific studies and experimental results, such as increases in IgG or the role of hepatic NPC1L1, suggesting moderate depth of analysis and active exploration of mechanisms.

ImpactModerate impact

While the discussions highlight significant potential factors involved in the disease, they primarily reflect scientific curiosity rather than immediate clinical or societal impact.

Abstract in brief

  • Cholesterol gallstone disease is highly prevalent in Europe and the USA, with gallstones being the most common digestive issue requiring hospital admission, and involves complex liver and gastrointestinal functions related to lipid regulation.
  • Recent scientific advances have identified key proteins and genes involved in cholesterol absorption, synthesis, and breakdown, helping to understand how excess biliary cholesterol leads to gallstone formation.
  • The formation of gallstones involves physical and chemical processes in bile and the activity of the gallbladder and intestines, with ongoing research exploring potential gene-based therapies and identifying gaps in our understanding of the disease's development.]
Read the full abstract

Top posts

Most liked on X and Bluesky
raulvelamazan
@raulvelamazan · X

Biblio: https://t.co/KU54LHMZqd https://t.co/4WgqYV8Xe7

May 7, 2023 · 3 likes · 2 shares · 3,062 followers View post →
EurekaMag
@EurekaMag · X

Role of biliary immunoglobulins on cholesterol gallstone disease Marked increase of IgG in gallbladder bile of gallstone patients https://t.co/boa5ReeCR9

May 1, 2025 · 6,445 followers View post →
EurekaMag
@EurekaMag · X

Thyroid Dysfunction and Cholesterol Gallstone Disease https://t.co/FYjunPm56P

Jul 2, 2020 · 2 shares · 6,445 followers View post →
POPLINE
@POPLINE_org · X

RT @EurekaMag: Thyroid Dysfunction and Cholesterol Gallstone Disease https://t.co/FYjunPm56P

Jul 2, 2020 · 2 shares · 5,273 followers View post →
THE MAC
@NotTheMacAnon1 · X

@RandyRu25576951 Our results suggest that the cholesterol saturation index and the activity of cholesterol nucleation promoting factors are the most important factors in the pathogenesis of cholesterol gallstone disease

May 13, 2024 · 3,791 followers View post →
Science Alerts
@Science_Alerts · X

RT @EurekaMag: Thyroid Dysfunction and Cholesterol Gallstone Disease https://t.co/FYjunPm56P

Jul 2, 2020 · 2 shares · 1,241 followers View post →

All mentions

EurekaMag
@EurekaMag · X

Role of biliary immunoglobulins on cholesterol gallstone disease Marked increase of IgG in gallbladder bile of gallstone patients https://t.co/boa5ReeCR9

May 1, 2025 · 6,445 followers View post →
THE MAC
@NotTheMacAnon1 · X

@RandyRu25576951 Our results suggest that the cholesterol saturation index and the activity of cholesterol nucleation promoting factors are the most important factors in the pathogenesis of cholesterol gallstone disease

May 13, 2024 · 3,791 followers View post →
AAVpapers
@AAVpapers · X

Effect of hepatic NPC1L1 on cholesterol gallstone disease and its mechanism https://t.co/iwxVZ076cz https://t.co/O7ucR3SP0i

May 9, 2023 · 147 followers View post →
Phage Papers
@Phage_Papers · X

Effect of hepatic NPC1L1 on cholesterol gallstone disease and its mechanism https://t.co/z1Fh8F7Q9i

May 9, 2023 · 648 followers View post →
Ivana Giménez
@ivanitag14 · X

RT @raulvelamazan: Biblio: https://t.co/KU54LHMZqd https://t.co/4WgqYV8Xe7

May 7, 2023 · 2 shares · 301 followers View post →
raulvelamazan
@raulvelamazan · X

Biblio: https://t.co/KU54LHMZqd https://t.co/4WgqYV8Xe7

May 7, 2023 · 3 likes · 2 shares · 3,062 followers View post →
Science Alerts
@Science_Alerts · X

RT @EurekaMag: Thyroid Dysfunction and Cholesterol Gallstone Disease https://t.co/FYjunPm56P

Jul 2, 2020 · 2 shares · 1,241 followers View post →
POPLINE
@POPLINE_org · X

RT @EurekaMag: Thyroid Dysfunction and Cholesterol Gallstone Disease https://t.co/FYjunPm56P

Jul 2, 2020 · 2 shares · 5,273 followers View post →
EurekaMag
@EurekaMag · X

Thyroid Dysfunction and Cholesterol Gallstone Disease https://t.co/FYjunPm56P

Jul 2, 2020 · 2 shares · 6,445 followers View post →