Uso de sustratos durante el ayuno #dieta #ayuno #metabolismo https://t.co/hd5Z2o1KAV https://t.co/NSUDqWgNeW
Fuel metabolism in starvation.
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Nov 2018 – Aug 2025Where it's discussed
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What people are saying
Overall, discussions reflect strong interest and agreement, with many users citing Cahill’s findings on ketones and metabolic flexibility, and sharing videos or studies about fasting durations and biochemical processes, indicating both scientific curiosity and practical applications.
Most discussions agree with the scientific points in Cahill’s work, highlighting the role of ketones and fuel metabolism during starvation.
The group demonstrates high interest, engaging with technical details about metabolic processes and sharing related studies.
Posts are relatively deep, citing Cahill’s research, discussing biochemical mechanisms, and sharing videos and personal fasting experiences.
The discussions show moderate impact, emphasizing the significance of understanding fuel metabolism for health, fasting, and therapeutic applications.
Abstract in brief
- This article reflects the author's journey from clinical practice to research and teaching, highlighting their experiences with fuel metabolism, especially during starvation, and how understanding these processes has evolved over time.
- Key scientific points include the discovery of the importance of insulin and free fatty acids in energy metabolism, particularly how the body manages fuel during prolonged starvation, with a focus on substances like betahydroxybutyric acid that support survival and may offer therapeutic benefits.
- The author emphasizes that advances in measuring and understanding these metabolic processes, driven by techniques like indirect calorimetry, have broadened our knowledge of human physiology and opened up potential medical applications, such as treating ischemic conditions.]
Top posts
Most liked on X and Bluesky"Not well known, however, is the metabolism of the human newborn, which is essentially ketotic. Maternal colustrum contains much TG and protein, but little lactose, starting man’s entry into society on an Atkins diet" G. Cahill https://t.co/ZQTKG0zZiR https://t.co/yLcWeR63FY
Fuente
Fuente
omg, the ADA in 2024, the brain needs glucose from carbohydrdates
I'll admit it was hard to find non-starvation data in humans (aka a protein free diet in humans but I didn't search endlessly) but I think these get the point across: https://t.co/DDfWeXdSuW https://t.co/e2Sh9f60YL https://t.co/qmif3X9pJM https://t.co/hSCQxgsFZj https://t.co/m0rbG4GFFY https://t.co/s7mGm4e8i5
All mentions
Essential Keto Tips and Insights into Fuel Metabolism During Starvation
This video shares key keto diet tips and explores fuel metabolism during starvation, highlighting the roles of insulin, free fatty acids, and substances like betahydroxybutyric acid in supporting survival and…
Understanding 20-Hour Fasting Schedule and Benefits
This video provides a detailed 20-hour fasting schedule, explaining what to do each hour, benefits, and proper fasting and breaking methods. It compares 20-hour fasting with shorter fasts and discusses beneficial…
Optimal Fasting Duration for Belly Fat Loss Based on Fuel Metabolism Insights
The best benefits of fasting start at 16 hours. This video explores how understanding fuel metabolism during starvation, including insulin and free fatty acids, can optimize fasting strategies for fat loss and potential…
Managing Hypoglycemia Risks on a Keto Diet with Starvation Metabolism Insights
This video addresses concerns about low glucose levels on a keto diet, focusing on how fuel metabolism during starvation, including the role of ketosis and fatty acids, supports stable energy levels and survival during…
Brain Metabolism Scaling and Implications for Neuronal Activity and Evolution
This video explores how brain metabolism scales with a fixed energy budget per neuron, impacting neuronal activity, plasticity, and evolutionary processes. It discusses current research findings and their implications…
How Hunger Triggers Body's Cell-Fueling Mechanisms
When you do not eat, the body activates various mechanisms to supply energy to its cells. Some cells are sacrificed to feed others, highlighting the complex regulation of energy during fasting and its impact on brain…
Understanding Fuel Metabolism During Starvation and its Medical Implications
This video explores how the body manages fuel during prolonged starvation, emphasizing the roles of insulin, free fatty acids, and ketone bodies like betahydroxybutyric acid. It highlights advances in measurement…
Understanding Fuel Metabolism During Starvation and Its Clinical Implications
This video explores fuel metabolism during starvation, emphasizing the roles of insulin, free fatty acids, and betahydroxybutyric acid. It highlights recent advances in measurement techniques like indirect calorimetry…
Debunking the Protein Myths and Understanding Gluconeogenesis
Think your steak is secretly a doughnut? In this video, we explore the science behind gluconeogenesis, debunking myths that excess protein turns into sugar, and explaining how your body efficiently handles protein for…
Scientific Insights into Intermittent Fasting and Fuel Metabolism During Starvation
Exploring the science behind intermittent fasting, this video discusses its effects on energy, aging, and metabolism, including insights from fuel management during starvation, highlighting key roles of insulin, free…
Understanding Blood Test Anomalies on Keto and Carnivore Diets
If you've been following a keto or carnivore diet and your bloodwork shows unusual results, this video explains why some values fall outside normal ranges and why that's not necessarily concerning. Aimed at providing…
What Happens to Your Body When You Fast (5 Stages of Fasting Explained for Beginners)
RT @caloriesproper2: Fuel Metabolism in Starvation (Cahill, 2006) https://t.co/JON7P1fuwA https://t.co/j8HSaGprNS
RT @caloriesproper2: Fuel Metabolism in Starvation (Cahill, 2006) https://t.co/JON7P1fuwA https://t.co/j8HSaGprNS
Fuel Metabolism in Starvation (Cahill, 2006) https://t.co/JON7P1fuwA https://t.co/j8HSaGprNS
The Protein Myth BUSTED: Why Steak Isn’t Turning Into Sugar #Gluconeogenesis #Keto #Carnivore https://t.co/hJV38HJfSp
FACTASY
Keto & Carnivore Blood Test Anomalies EXPLAINED https://t.co/9scEM3dNnR via @YouTube
@xeff @KasprzykRemi "dans certaines conditions, comme lors d'un jeûne prolongé, le cerveau peut également utiliser des corps cétoniques comme source d'énergie alternative." Bref, c'est anecdotique. https://t.co/67xeTSG8JS Avec cela je maintiens que le glucose est le principal carburant du cerveau.
Brain substrate utilization in three fasting obese volunteers after several weeks of starvation (48, 49). Many studies suggest human brain cells can survive with little to no glucose, but proving the point is difficult. Cahill, G. F. (2006). Fuel Metabolism in Starvation. https://t.co/9DBuF4yg4k
The Absolute Best Fasting Length to Lose Belly Fat is NOT 16 Hours… Do T... https://t.co/ukvzVlcMvV via @YouTube
@kagashin_sub 多分糖新生のことだと思うけど、消費量は定量化されてないのかな? 結局48時間経過頃にはケトジェニックになるから分解量には限りがあると思うが(下図、Fuel metabolism in starvation GF Cahill Jr) https://t.co/nPfLlpYhbs
RT @AntelmPujol: Fuente
Fuente
omg, the ADA in 2024, the brain needs glucose from carbohydrdates
@HelleputteSimon https://t.co/PEFsCtJGIf George Cahill Fuel metabolism during starvation
I found it. It's "Fuel metabolism in starvation" from George Cahil. https://t.co/RYBk6r2qjN
RT @AntelmPujol: Fuente
Fuente
@Arturogarzaest @AntelmPujol https://t.co/auoM2NgG6e
RT @IberianCitizen: Uso de sustratos durante el ayuno #dieta #ayuno #metabolismo https://t.co/hd5Z2o1KAV https://t.co/NSUDqWgNeW
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RT @IberianCitizen: Uso de sustratos durante el ayuno #dieta #ayuno #metabolismo https://t.co/hd5Z2o1KAV https://t.co/NSUDqWgNeW
RT @IberianCitizen: Uso de sustratos durante el ayuno #dieta #ayuno #metabolismo https://t.co/hd5Z2o1KAV https://t.co/NSUDqWgNeW
RT @IberianCitizen: Uso de sustratos durante el ayuno #dieta #ayuno #metabolismo https://t.co/hd5Z2o1KAV https://t.co/NSUDqWgNeW
RT @IberianCitizen: Uso de sustratos durante el ayuno #dieta #ayuno #metabolismo https://t.co/hd5Z2o1KAV https://t.co/NSUDqWgNeW
RT @IberianCitizen: Uso de sustratos durante el ayuno #dieta #ayuno #metabolismo https://t.co/hd5Z2o1KAV https://t.co/NSUDqWgNeW
RT @IberianCitizen: Uso de sustratos durante el ayuno #dieta #ayuno #metabolismo https://t.co/hd5Z2o1KAV https://t.co/NSUDqWgNeW
RT @IberianCitizen: Uso de sustratos durante el ayuno #dieta #ayuno #metabolismo https://t.co/hd5Z2o1KAV https://t.co/NSUDqWgNeW
RT @IberianCitizen: Uso de sustratos durante el ayuno #dieta #ayuno #metabolismo https://t.co/hd5Z2o1KAV https://t.co/NSUDqWgNeW
RT @IberianCitizen: Uso de sustratos durante el ayuno #dieta #ayuno #metabolismo https://t.co/hd5Z2o1KAV https://t.co/NSUDqWgNeW
RT @IberianCitizen: Uso de sustratos durante el ayuno #dieta #ayuno #metabolismo https://t.co/hd5Z2o1KAV https://t.co/NSUDqWgNeW
RT @IberianCitizen: Uso de sustratos durante el ayuno #dieta #ayuno #metabolismo https://t.co/hd5Z2o1KAV https://t.co/NSUDqWgNeW
RT @IberianCitizen: Uso de sustratos durante el ayuno #dieta #ayuno #metabolismo https://t.co/hd5Z2o1KAV https://t.co/NSUDqWgNeW
RT @IberianCitizen: Uso de sustratos durante el ayuno #dieta #ayuno #metabolismo https://t.co/hd5Z2o1KAV https://t.co/NSUDqWgNeW
RT @IberianCitizen: Uso de sustratos durante el ayuno #dieta #ayuno #metabolismo https://t.co/hd5Z2o1KAV https://t.co/NSUDqWgNeW
RT @IberianCitizen: Uso de sustratos durante el ayuno #dieta #ayuno #metabolismo https://t.co/hd5Z2o1KAV https://t.co/NSUDqWgNeW
RT @IberianCitizen: Uso de sustratos durante el ayuno #dieta #ayuno #metabolismo https://t.co/hd5Z2o1KAV https://t.co/NSUDqWgNeW
RT @IberianCitizen: Uso de sustratos durante el ayuno #dieta #ayuno #metabolismo https://t.co/hd5Z2o1KAV https://t.co/NSUDqWgNeW
RT @IberianCitizen: Uso de sustratos durante el ayuno #dieta #ayuno #metabolismo https://t.co/hd5Z2o1KAV https://t.co/NSUDqWgNeW
RT @IberianCitizen: Uso de sustratos durante el ayuno #dieta #ayuno #metabolismo https://t.co/hd5Z2o1KAV https://t.co/NSUDqWgNeW
RT @IberianCitizen: Uso de sustratos durante el ayuno #dieta #ayuno #metabolismo https://t.co/hd5Z2o1KAV https://t.co/NSUDqWgNeW
RT @IberianCitizen: Uso de sustratos durante el ayuno #dieta #ayuno #metabolismo https://t.co/hd5Z2o1KAV https://t.co/NSUDqWgNeW
RT @IberianCitizen: Uso de sustratos durante el ayuno #dieta #ayuno #metabolismo https://t.co/hd5Z2o1KAV https://t.co/NSUDqWgNeW
RT @IberianCitizen: Uso de sustratos durante el ayuno #dieta #ayuno #metabolismo https://t.co/hd5Z2o1KAV https://t.co/NSUDqWgNeW
RT @IberianCitizen: Uso de sustratos durante el ayuno #dieta #ayuno #metabolismo https://t.co/hd5Z2o1KAV https://t.co/NSUDqWgNeW
RT @IberianCitizen: Uso de sustratos durante el ayuno #dieta #ayuno #metabolismo https://t.co/hd5Z2o1KAV https://t.co/NSUDqWgNeW
RT @IberianCitizen: Uso de sustratos durante el ayuno #dieta #ayuno #metabolismo https://t.co/hd5Z2o1KAV https://t.co/NSUDqWgNeW
RT @IberianCitizen: Uso de sustratos durante el ayuno #dieta #ayuno #metabolismo https://t.co/hd5Z2o1KAV https://t.co/NSUDqWgNeW
RT @IberianCitizen: Uso de sustratos durante el ayuno #dieta #ayuno #metabolismo https://t.co/hd5Z2o1KAV https://t.co/NSUDqWgNeW
RT @IberianCitizen: Uso de sustratos durante el ayuno #dieta #ayuno #metabolismo https://t.co/hd5Z2o1KAV https://t.co/NSUDqWgNeW
RT @IberianCitizen: Uso de sustratos durante el ayuno #dieta #ayuno #metabolismo https://t.co/hd5Z2o1KAV https://t.co/NSUDqWgNeW
RT @IberianCitizen: Uso de sustratos durante el ayuno #dieta #ayuno #metabolismo https://t.co/hd5Z2o1KAV https://t.co/NSUDqWgNeW
Uso de sustratos durante el ayuno #dieta #ayuno #metabolismo https://t.co/hd5Z2o1KAV https://t.co/NSUDqWgNeW
@exfatloss @StevenMBelknap @KetoCarnivore Possibly George F. Cahill, Jr.? E.g. Fuel metabolism in starvation (2006) https://t.co/lyW1jnHe9q
@exfatloss @luis_villasenor Your answer is here. https://t.co/hGuMHXLbbb
@normalishvegan The text in my tweet is *quoted verbatim* from the abstract of the source. Here’s another article showing plasma ß-hydroxybutyrate levels rise after breast-feeding in infants and remain high until the next feeding. Ketosis is a normal state for infants. https://t.co/KgFfsYk4Nn https://t.co/ZbT5DscxN4
RT @AKoutnik: @CaloriesProper Even at incredibly low levels during multiday fasting, "0" is not reached.https://t.co/PEFsCtrxu7 shows this…
@CaloriesProper Even at incredibly low levels during multiday fasting, "0" is not reached.https://t.co/PEFsCtrxu7 shows this as BHB would cont to rise 0 insulin (as it does in T1D) During T1D, 0 can be reached and death will follow without intervention with days.
RT @IsraelPodesta: @Gonzalez_JT Something which is very interesting, as it seems that on the first days of life, the neonate has an upregul…
@Gonzalez_JT Something which is very interesting, as it seems that on the first days of life, the neonate has an upregulated metabolism for βOHB, contradicting the intrauterine fuel preferences. https://t.co/sDcQ6MO9WC https://t.co/ozAlXV9Ktc https://t.co/TnvyBTrxR4
I'll admit it was hard to find non-starvation data in humans (aka a protein free diet in humans but I didn't search endlessly) but I think these get the point across: https://t.co/DDfWeXdSuW https://t.co/e2Sh9f60YL https://t.co/qmif3X9pJM https://t.co/hSCQxgsFZj https://t.co/m0rbG4GFFY https://t.co/s7mGm4e8i5
@IdanOnTweeter @BenBikmanPhD happy to update those numbers however, I doubt we're going to find experiments that push these metabolic limits further than this one did, that found ~ 1/3 https://t.co/6GST3Vvn0n (emphasis: approximately)
糖質がゼロに近い状態だと、 1日に作られるのブドウ糖は80g程度。 →乳酸・ピルビン酸-35-40g 脂肪・グリセロール-20g アミノ酸(主にアラニン)-15g ケトン体-10g FUEL METABOLISM IN STARVATION George F. Cahill, Jr.2006 https://t.co/e5cxGULpgc
RT @NaughtyNomad: 20-hour fasts are my favourite (2-3 times a week). Easy to do and very effective. This is a great video guide... http…
20-hour fasts are my favourite (2-3 times a week). Easy to do and very effective. This is a great video guide... https://t.co/i8znT97GV5
How to do a 20 Hour Fast - FULL Schedule & Timing https://t.co/ceNKYTAAuy
@Cadexin @OtraHistoriaYT No, a ver, lo publicó en mi último vídeo xD https://t.co/AaZWHDrwMe Lo que me he podido reír leyendo ese comentario... Es tan grande... Casi me cambio el nombre a "pinche biomoleco" jajaja
@R7_Takion @SchrodingerGata Buenas! Tu cuerpo puede frabricar glucosa (principal carbohidrato) a partir de proteínas y grasas, y proveer al cerebro con cetonas a partir de las grasas como fuente alternativa de energía! No es necesario consumir carbohidratos en gran cantidad! https://t.co/wajCvqogF8
@_yousuffer @SchrodingerGata @Tras_los_Muros Buenas! Los carbohidratos proveen glucosa para tu cerebro, es cierto, pero si no los comes, tu cuerpo puede frabricar glucosa a partir de proteínas y grasas, y proveer al cerebro con cetonas a partir de las grasas como fuente alternativa de energía! https://t.co/wajCvqogF8
@snahuel911 @SchrodingerGata Es cierto que no de vitaminas, aunque sean necesarias en la dieta en su cierta medida. Sin embargo, si no tienes desórdenes de metabolismo, una persona puede vivir tranquilamente obteniendo su energía de las grasas y proteínas. Te cuento como funciona aquí https://t.co/jAyLUDzuA3
@GBCLopi @SchrodingerGata Te lo explico en mi último vídeo! https://t.co/jAyLUDzuA3
¡¡¡HAY VÍDEO NUEVO!!! --> https://t.co/F87Ope5QK4 Si no te alimentas, ¡tu cerebro se empieza a comer a tu cuerpo! ¡Es un zombie al revés! Si queréis saber por qué y cómo ocurre, ¡dadle un vistazo! ¡Espero que lo disfrutéis! :) https://t.co/mSxhjMZr5j
5 Keto Diet Tips I Wish I Knew Back in 2015 https://t.co/k8CelbEpiA via @YouTube i.e. Compress your meal-eating window, test glucose & ketones, eat more salt, after 3 months, carbs (berries etc) okay, lower calorie works when fat adapted.
@DominicDAgosti2 Cahill Fuel Metabolism in Starvation: β-HYDROXYBUTYRATE: THE MOST EFFICIENT FUEL Veech and colleagues discovered that administering β-hydroxybutyrate to the perfused rat heart in place of glucose increased work output but decreased oxygen consumption (35). https://t.co/P2CX9oul5G
RT @su_js1: @garytaubes Cahill Fuel Metabolism in Starvation: β-HYDROXYBUTYRATE: THE MOST EFFICIENT FUEL Veech and colleagues discovered th…
RT @su_js1: @garytaubes Cahill Fuel Metabolism in Starvation: β-HYDROXYBUTYRATE: THE MOST EFFICIENT FUEL Veech and colleagues discovered th…
@garytaubes Cahill Fuel Metabolism in Starvation: β-HYDROXYBUTYRATE: THE MOST EFFICIENT FUEL Veech and colleagues discovered that administering β-hydroxybutyrate to the perfused rat heart in place of glucose increased work output but decreased oxygen consumption (35). https://t.co/P2CX9oLWug
@_deepfire @raphaels7 @upyrbike @coliri2 @johnosti @OZmandia @tednaiman @dramerling @DikemanDave @Mangan150 @p70S6K @ColinChampMD @DaveKeto @ChrisWebsterSA @ProfTimNoakes @ketonemics @DrEades @HyperlipidM @gerdosi I’d start with Cahill, Fuel Metabolism in Starvation.
@whatsup_docs @ThatCG1801 It's not. Both can happen at the same time. Gluconeogenesis happens all the time. https://t.co/6gSsFGJern › ...PDF Fuel Metabolism in Starvation - The Health Sciences Academy
Fuel Metabolism in Starvation | Annual Review of Nutrition https://t.co/lNCEsXI6sm
@NNeanderMedical @davidludwigmd @bschermd @BenBikmanPhD @foundmyfitness @garytaubes @DrEenfeldt @JimJohnsonSci @ethanjweiss @drericwestman @JakeKushnerMD No, sorry. The links was left out from my reply above. Fuel Metabolism in Starvation https://t.co/7JX9OB04GS
@kei555go こちらをご覧になってみて下さい
@DiscoStew66 @jcsouto Cahill Fuel Metabolism in Starvation: β-HYDROXYBUTYRATE: THE MOST EFFICIENT FUEL Veech and colleagues discovered that administering β-hydroxybutyrate to the perfused rat heart in place of glucose increased work output but decreased oxygen consumption (35). https://t.co/P2CX9oul5G
5 Keto Diet Tips I Wish I Knew Back in 2015 https://t.co/hDRbWsi2zI via @YouTube
@NachoJulian1 @Borjawy Este es interesante El metabolismo del combustible en la inanición https://t.co/k1vVUzAsah https://t.co/07BmcMy7ic
RT @natureboyrr: Great video from @MikeMutzel! Highly recommended for anyone pursuing life as a fat-adapted, fat-burning ketogenic beast. T…
Great video from @MikeMutzel! Highly recommended for anyone pursuing life as a fat-adapted, fat-burning ketogenic beast. TRE more important on ketogenic diets. Less heat loss in Krebs cycle
@cadiulus @JakeKushnerMD @KetoAnaesMD @upyrbike @gasman5757 @d_magpie @DrScottMurray @FructoseNo @roryjheath @drtroystapleton @DominicDAgosti2 @BostonChildrens https://t.co/Pq062YMDly
FUEL METABOLISM INSTARVATION https://t.co/SogH5rMqqK "β-hydroxybutyric acid not only has permitted man to survive prolonged starvation, but also may have therapeutic potential owing to its greater efficiency in providing cellular energy in ischemic states such as stroke...
RT @gfj1979: "Not well known, however, is the metabolism of the human newborn, which is essentially ketotic. Maternal colustrum contains…
RT @gfj1979: "Not well known, however, is the metabolism of the human newborn, which is essentially ketotic. Maternal colustrum contains…
RT @gfj1979: "Not well known, however, is the metabolism of the human newborn, which is essentially ketotic. Maternal colustrum contains…
RT @gfj1979: "Not well known, however, is the metabolism of the human newborn, which is essentially ketotic. Maternal colustrum contains…
"Not well known, however, is the metabolism of the human newborn, which is essentially ketotic. Maternal colustrum contains much TG and protein, but little lactose, starting man’s entry into society on an Atkins diet" G. Cahill https://t.co/ZQTKG0zZiR https://t.co/yLcWeR63FY
@JeffMindrup @momstrosityy Cahill, George F., Jr. “Fuel Metabolism in Starvation.” Annual Review of Nutrition 26 (2006)
@JeffMindrup @momstrosityy ❤️ https://t.co/KeZvMHJg0E
I just posted "Fuel metabolism in starvation - 2006" on Reddit https://t.co/lb243eigh1
@ketonemics @cadiulus @NoonesFirstNan @kevinnbass @AKoutnik @JakeKushnerMD That is from Cahill ‘FUEL METABOLISM IN STARVATION’ 2006, without T1D (see figure text) https://t.co/jCgYvuPXwk
@DrStephenHussey @FatEmperor @DNSWilson @siobhan_huggins @erreyedoc @TuckerGoodrich @DaveKeto Cahill Fuel Metabolism in Starvation: β-HYDROXYBUTYRATE: THE MOST EFFICIENT FUEL Veech and colleagues discovered that administering β-hydroxybutyrate to the perfused rat heart in place of glucose increased work output but decreased oxygen consumption (35). https://t.co/P2CX9oul5G
@DrPaulMason @Sadrien_GW2 @GeorgiaEdeMD @KetoCarnivore @lowcarbGP @ProfTimNoakes @FructoseNo Cahill "Fuel metabolism in starvation"