December 2006 PMID 17178554

Testosterone and the brain.

Michael Zitzmann

Mentions

28
Peak: 2 in Jul 2022
across 4 sources since Aug 2021

Extended reach

246,322
potential audience

Total likes

176

Video views

219,875

Mentions per month

Aug 2021 – Nov 2025

Where it's discussed

  • X / Twitter20 posts
  • Facebook4 posts
  • YouTube2 videos
  • Reddit2 posts

AI synopsis

What people are saying

The collective discussions show support for the publication by highlighting testosterone's role in cognition, mood, and brain development, with some posts referencing scientific studies to back their claims, while others challenge misinformation, indicating both interest and engagement driven by the hormone's broad influence.

AgreementModerate agreement

Most discussions support the positive effects of testosterone on brain health and cognition, as evidenced by posts emphasizing testosterone's role in mental functions and correcting misinformation.

InterestHigh interest

The posts demonstrate a high level of curiosity and concern about testosterone's impact on mental health, brain development, and social behavior.

EngagementModerate engagement

Many posts reference scientific studies, personal experiences, and factual clarifications, indicating a moderate depth of engagement with the material.

ImpactModerate impact

The discussions reflect a recognition of testosterone's importance for mental well-being and social functioning, which can influence attitudes towards hormonal health.

Abstract in brief

  • Testosterone influences brain functions by activating a network involved in spatial recognition, and supplementing it can improve spatial skills in both younger and older men with low testosterone levels.
  • Reduced testosterone is linked to depression, and testosterone therapy can help improve mood, especially in individuals with specific genetic profiles.
  • While testosterone is often associated with aggression, its primary effects in hypogonadal men seem to be boosting positive traits like energy and vigor, rather than increasing aggressive behaviors.]

Top posts

Most liked on X and Bluesky
White Pantheress
@wpantheress · X

@CatgirIAmy @Celesteialcutie @jk_rowling You should have some, low testosterone brings a host of brain problems

Nov 3, 2021 · 5 likes · 41 followers View post →
junglehoney
@KruseYouri · X

such as vigour and energy." https://t.co/UQgpaNFpQW

Dec 19, 2022 · 4 likes · 13,378 followers View post →
Dr. Alex Tatem
@alextatem · X

Apr 26, 2025 · 4 likes · 2 shares · 4,417 followers View post →
Trevor Maddi
@TMaddi · X

@jcarole @MarcLobliner @bcuban Fact check: false. Actual scientist here, there are numerous studies that validate an increase in cognitive function and brain health with TRT use. https://t.co/cdo5WexPa9 DOI: 10.1080/13685530601040679 Btw, you are transphobic spreading misinformation about hormone use!

Nov 1, 2024 · 3 likes · 88 followers View post →
Ankush Datar
@ankushd14 · X

Lack of passion/focus in life can come from reduced testosterone levels. So ironic that lack of focus on exercise, sleep and nutrition- the pillars required for optimal testosterone production- can cause lack of focus/passion in other activities of life https://t.co/UfEAVZCDF3

Feb 10, 2022 · 2 likes · 3,444 followers View post →
The Incredible Fella
@micoleaomacaco · X

@theredmake @kil_ag @melaogustavo Cara, tem muita coisa no Pubmed, é só procurar. Neste momento você está bancando o negacionista por dissonância cognitiva https://t.co/RCrStDYOJD.

Nov 13, 2022 · 2 likes · 97 followers View post →

All mentions

TestosteroneMastery
@MasterYourT · X

Zinc deficiency can drop testosterone by up to 60%. In controlled studies, men on a zinc restricted diet saw their levels fall from 39.9 nmol/L to 10.6 nmol/L in just 20 weeks. Zinc supports the enzymes that make testosterone and the brain hormones that trigger it. Without it, https://t.co/qd0TMNXGNQ

Nov 4, 2025 · 55 followers View post →
Eric Campbell
@NATerrent127 · X

@__Passie__ @RealMattCouch Learned it when I took Developmental Biology 25 years ago…might have been Endocrinology. Pretty sure the boy’s body in-utero converts the estrogen to testosterone and the brain wires itself accordingly.

Sep 18, 2025 · 899 followers View post →
Cdbrown
@BrowntownBrew · X

@TheLaurenChen The person is already producing testosterone and the brain is triggering the release of all sorts of other chemicals making the person feel like they are in the wrong body.

Sep 17, 2025 · 166 followers View post →
Rodney Leonard
@leonard5691 · X

Testosterone and the brain - PubMed https://t.co/H9lB1WIPAe

Jul 23, 2025 · 79 followers View post →
Mitsu Health
@MitsuMaHealth · X

Something to think about: Men with low testosterone are more prone to anxiety and social withdrawal. Where does courage come from when chemistry dims? Zitzmann, Michael, and Eberhard Nieschlag. “Testosterone and the Brain.” European Journal of Endocrinology 151, no. 4 (2004):

Jun 2, 2025 · 493 followers View post →
Full time sober
@Ptrmlln159957 · X

RT @alextatem:

May 3, 2025 · 2 shares · 806 followers View post →
Glen Watson
@GlenWatson9570 · X

RT @alextatem:

Apr 26, 2025 · 2 shares · 1,090 followers View post →
Dr. Alex Tatem
@alextatem · X

Apr 26, 2025 · 4 likes · 2 shares · 4,417 followers View post →
Trevor Maddi
@TMaddi · X

@jcarole @MarcLobliner @bcuban Fact check: false. Actual scientist here, there are numerous studies that validate an increase in cognitive function and brain health with TRT use. https://t.co/cdo5WexPa9 DOI: 10.1080/13685530601040679 Btw, you are transphobic spreading misinformation about hormone use!

Nov 1, 2024 · 3 likes · 88 followers View post →
Theclipclipper
@theclipclipper · X

@dippedinpiss @aceywacey__ @jordanbpeterson https://t.co/eMsngFQWLi The brain develops differently depending on what sex you are at puberty. Men's and women's brains are different and testosterone and estrogen have different effects. If you prevent the introduction of any hormones at puberty the brain just won't develop.

Mar 13, 2023 · 19 followers View post →
junglehoney
@KruseYouri · X

such as vigour and energy." https://t.co/UQgpaNFpQW

Dec 19, 2022 · 4 likes · 13,378 followers View post →
EvilEye
@Lavende23250367 · X

Testosterone and the brain https://t.co/KqQ1shfD6E

Dec 5, 2022 · 7 followers View post →
The Incredible Fella
@micoleaomacaco · X

@theredmake @kil_ag @melaogustavo Cara, tem muita coisa no Pubmed, é só procurar. Neste momento você está bancando o negacionista por dissonância cognitiva https://t.co/RCrStDYOJD.

Nov 13, 2022 · 2 likes · 97 followers View post →
kati manoto
@katimanoto · X

Testosterone and the brain https://t.co/KaN7w0lpno

Sep 14, 2022 · 1 like · 400 followers View post →
Rem
@JJJJJJJJJJJUwU · X

@Bluewallprivate @terfinathegreat @JaywalkingGuy @saveusculture @WomenPostingLs @keffals reduced testosterone is associated with depressive disorders https://t.co/nz4FJV8U6d.

Jul 20, 2022 · 37 followers View post →
Dela Sverige
@DelaSverige · X

@LeenaJohansson @JennyFranzen4 @space_swede @barentsdx @Karatemerzis Henrik kom med påståendet att tjejer är bättre på matte och de är de inte. Tyckte du artikeln sa det? Den dokumentär jag pratat om med testosterones inverkan på hjärnans struktur behandlar liknande denna: https://t.co/21k03w3bp1

Jul 10, 2022 · 820 followers View post →
Ankush Datar
@ankushd14 · X

Lack of passion/focus in life can come from reduced testosterone levels. So ironic that lack of focus on exercise, sleep and nutrition- the pillars required for optimal testosterone production- can cause lack of focus/passion in other activities of life https://t.co/UfEAVZCDF3

Feb 10, 2022 · 2 likes · 3,444 followers View post →
Noth
@Nothv13 · X

@ComicMojo @0coin2wholecoin @AndrewYang Testosterone literally activates brain pathways and improves spatial cognition. Hell a lack of it even plays a role in depression. https://t.co/fywxgDW1LN

Jan 28, 2022 · 1 like · 42 followers View post →
White Pantheress
@wpantheress · X

@CatgirIAmy @Celesteialcutie @jk_rowling You should have some, low testosterone brings a host of brain problems

Nov 3, 2021 · 5 likes · 41 followers View post →
Malay Man
@lightsofmorning · X

@DewEnjoyer @boreddeleuzian @masculinesoul @TwigTurk For mental wellness, read here : https://t.co/FSeMHxDByP It is more than just physical characteristics. You NEED to be mentally well to LEAD. Thus, T is the main mental factor. Don't be foolish towards this hormone, it's essential to civillization.

Aug 11, 2021 · 58 followers View post →