Als er das erfuhr, war er extrem erleichtert, und innerhalb von Minuten ging es ihm wieder besser. Es ist ein bemerkenswerter Fall einer Placebo-Überdosis. Originalpublikation: pubmed.ncbi.nlm.nih.gov/17484949/
Nocebo effects with antidepressant clinical drug trial placebos.
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Apr 2019 – Dec 2025Where it's discussed
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X / Twitter43 posts
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News20 articles
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Facebook15 posts
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Blogs8 articles
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Bluesky2 posts
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AI synopsis
What people are saying
The collective discussions demonstrate strong interest, with examples like a case involving a man who overdosed on placebo pills and experienced severe symptoms, illustrating how negative expectations can produce real health effects. The tone varies from analytical to attentive, emphasizing the importance and potential implications of the nocebo effect for medical practice and research.
Most discussions agree that the article highlights important effects of nocebo phenomena, especially regarding symptoms resulting from negative expectations in trials.
Posts show high interest, referencing specific cases of overdose, severe symptoms, and implications for clinical research, indicating engagement with the topic.
Many posts deeply analyze the phenomenon, sharing detailed case examples, such as a man experiencing shock after placebo, suggesting active engagement.
Discussions recognize the significance of the findings, especially with phrases like 'remarkable case' or 'must read,' implying the article's potential influence on understanding placebo/nocebo effects.
Abstract in brief
- A 26-year-old man experienced severe negative symptoms, including hypotension, after taking placebo capsules in a clinical trial because he believed he was overdosing on an antidepressant.
- Once it was revealed that the capsules were inert, his symptoms quickly disappeared, demonstrating a nocebo effect—where negative expectations cause real side effects.
- The report suggests that nocebo effects can have serious impacts on patients and further research is needed to understand this phenomenon better.]
Top posts
Most liked on X and Blueskyokazało się, że pacjent był uczestnikiem badań klinicznych i otrzymywał placebo - po zapoznaniu pacjenta z tą informacją uzyskano prawie natychmiastowo prawidłowe wartości ciśnień a pacjent mogł samodzielnie opuścić placówkę https://t.co/kxf4Onv8cB https://t.co/CN1p2gO1Zr
Depressed man enrolls in antidepressant study. Pills helped at first. Then decided to end it. Took 29 pills. Regretted it. Went to the ER pale, drowsy, shaking with very low blood pressure. No toxins in his labs. He was on placebo pills. https://t.co/Rg80u419iS
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@knHammarhaj @OlofFlodin Utan att på någotvis uttala mig om kollegan, så kan nocebo (placebo, fast vid förväntade negativa effekter) ge förvånandsvärt starka effekter. Här t.ex. En man som "överdoserar" i en case study, men fick placebo. Fick farligt lågt blodtryck bla. https://t.co/MuQ9Whe2oj
@bobw075 Yep, all linked below: 1/10: https://t.co/PAXhDDil62 2/10: https://t.co/pZnUpJ46Gp 3-5/10: https://t.co/zCJqIO6d2e 6/10: https://t.co/DVSc9nShQS 7/10: https://t.co/xnnl4RTt4J 8/10: https://t.co/Yz2GjoRoez 9/10: https://t.co/K5aZfWtQZc
All mentions
Understanding the Nocebo Effect and Its Impact on Patients
Shorts on nocebo effect and placebo in medical trials. A patient experienced severe symptoms after believing he overdosed, only to recover once it was revealed the capsules were inert, highlighting how negative…
Understanding the Nocebo Effect and Its Impact on Healthcare Outcomes
This video explains the Nocebo Effect, its mechanisms, and its influence on patient outcomes. It discusses expectations, brain activity, and cases highlighting how negative perceptions can affect health, especially in…
RT @DrWojakMD: @bobw075 Yep, all linked below: 1/10: https://t.co/PAXhDDil62 2/10: https://t.co/pZnUpJ46Gp 3-5/10: https://t.co/zCJqIO6d2e…
Als er das erfuhr, war er extrem erleichtert, und innerhalb von Minuten ging es ihm wieder besser. Es ist ein bemerkenswerter Fall einer Placebo-Überdosis. Originalpublikation: pubmed.ncbi.nlm.nih.gov/17484949/
@KelleyKga @ID_Denmark Perhaps the Nocebo Effect contributes to Long Covid as well. For example, a case study suggests that a person who believes he has ingested something harmful - e.g. overdosing on antidepressants - can get sick, despite having received a placebo May 2007: https://t.co/8nalgq2MrO
https://t.co/0hgFDH4nc3
L'article s'appelle Nocebo effects with antidepressant clinical drug trial placebos. De Roy R. Reeves, Mark E. Ladner, Roy H. Hart, Randy S. Burke,, General Hospital Psychiatry, Vol. 29, Issue 3, May–June 2007, Pages 275-277 doi.org/10.1016/j.ge... Je l'ai mis ici. www.monvoisin.xyz/wp-content/u...
@bobw075 Yep, all linked below: 1/10: https://t.co/PAXhDDil62 2/10: https://t.co/pZnUpJ46Gp 3-5/10: https://t.co/zCJqIO6d2e 6/10: https://t.co/DVSc9nShQS 7/10: https://t.co/xnnl4RTt4J 8/10: https://t.co/Yz2GjoRoez 9/10: https://t.co/K5aZfWtQZc
@flagellumdei111 @PGPapanikolaou Δες αυτό... https://t.co/elgn5k1qw3 Επίσης, μπορείς να ξεχωρίσεις μεταξύ επίδρασηςιού, φαρμάκου ή φαινομένου nocebo, όταν εμφανίζουν και τα 3 τα ίδια συμπτώματα; https://t.co/DyalY3klHF https://t.co/30pD25Q2va
бф би лайк "можешь мне найти статью в открытом доступе?", и я такой мол "ну давай", и там нечто абсолютно феноменальное: https://t.co/worWnMiIiz
@_King_Turd @1960Ragnar @AlternativH https://t.co/MuQ9WheAdR Det går!
@mmoooose @shyam_lab The "effect" observed in the placebo arm of a trial is not necessarily The Placebo Effect; it could be RTM. On the other hand, there's stuff like this that probably can't be. https://t.co/lqZ3hhv1NT
@NeuroStats For example, this cannot possibly be regression to the mean. https://t.co/lqZ3hhv1NT
RT @Nawaf_i: جرعة زايدة من فكرة
RT @Nawaf_i: جرعة زايدة من فكرة
RT @Nawaf_i: جرعة زايدة من فكرة
RT @Nawaf_i: جرعة زايدة من فكرة
جرعة زايدة من فكرة
@knHammarhaj @OlofFlodin Utan att på någotvis uttala mig om kollegan, så kan nocebo (placebo, fast vid förväntade negativa effekter) ge förvånandsvärt starka effekter. Här t.ex. En man som "överdoserar" i en case study, men fick placebo. Fick farligt lågt blodtryck bla. https://t.co/MuQ9Whe2oj
RT @prokraustinator: @ruth_hook_ @zeta_globin @nickcammarata I can’t see how something like this could be *only* a statistical error. http…
@ruth_hook_ @zeta_globin @nickcammarata I can’t see how something like this could be *only* a statistical error. https://t.co/lqZ3hhv1NT
RT @DrAditya1996: The Power of the Nocebo effect! Case report of a 26/M who thought he consumed 29 tablets of his antidepressant and prese…
The Power of the Nocebo effect! Case report of a 26/M who thought he consumed 29 tablets of his antidepressant and presented to the ER with frank shock. Required resuscitation with 6L fluids. 1/2 https://t.co/kXmbE7QuyP
RT @DoctorJack16: Depressed man enrolls in antidepressant study. Pills helped at first. Then decided to end it. Took 29 pills. Regretted it…
RT @DoctorJack16: Depressed man enrolls in antidepressant study. Pills helped at first. Then decided to end it. Took 29 pills. Regretted it…
RT @DoctorJack16: Depressed man enrolls in antidepressant study. Pills helped at first. Then decided to end it. Took 29 pills. Regretted it…
Depressed man enrolls in antidepressant study. Pills helped at first. Then decided to end it. Took 29 pills. Regretted it. Went to the ER pale, drowsy, shaking with very low blood pressure. No toxins in his labs. He was on placebo pills. https://t.co/Rg80u419iS
RT @beksaIala: okazało się, że pacjent był uczestnikiem badań klinicznych i otrzymywał placebo - po zapoznaniu pacjenta z tą informacją uzy…
RT @beksaIala: okazało się, że pacjent był uczestnikiem badań klinicznych i otrzymywał placebo - po zapoznaniu pacjenta z tą informacją uzy…
okazało się, że pacjent był uczestnikiem badań klinicznych i otrzymywał placebo - po zapoznaniu pacjenta z tą informacją uzyskano prawie natychmiastowo prawidłowe wartości ciśnień a pacjent mogł samodzielnie opuścić placówkę https://t.co/kxf4Onv8cB https://t.co/CN1p2gO1Zr
This one should be required reading! A weird medical story about the nocebo effect. https://t.co/MlPehFpR1e
RT @ph_minimal: @S96405539 プラセボ効果って凄いですよね! 一方でノセボ効果の威力も凄いので情報発信には気を使います
@RyanMarino @FormerAntivax Classic case of nocebo. https://t.co/xB2lE33nKs
Nocebo effects with antidepressant clinical drug trial placebos - PubMed https://t.co/zZkXYcxwwK
RT @drsamko: @emlitofnote @MollyJongFast Nocebo effect can be strong - https://t.co/ioLNppRrIh
@emlitofnote @MollyJongFast Nocebo effect can be strong - https://t.co/ioLNppRrIh
Case study (2007) of a 26-year-old suicide attempt hospitalized for drug overdose who immediately recovered when he found he'd taken a placebo. https://t.co/Dc94YRbne1
@S96405539 プラセボ効果って凄いですよね! 一方でノセボ効果の威力も凄いので情報発信には気を使います
Overdosing on Placebos? Yup, it’s a thing. Nocebo effects with antidepressant clinical drug trial placebos. - PubMed - NCBI https://t.co/sKtdHruQKl
RT @broomedocs: Nocebo effects with antidepressant clinical drug trial placebos. - @First10EM @TheSGEM @EMManchester @srrezaie BLAC…
RT @broomedocs: Nocebo effects with antidepressant clinical drug trial placebos. - @First10EM @TheSGEM @EMManchester @srrezaie BLAC…
RT @broomedocs: Nocebo effects with antidepressant clinical drug trial placebos. - @First10EM @TheSGEM @EMManchester @srrezaie BLAC…
Nocebo effects with antidepressant clinical drug trial placebos. https://t.co/qBIRKwSCJs
Nocebo effects with antidepressant clinical drug trial placebos. - @First10EM @TheSGEM @EMManchester @srrezaie BLACK BOX WARNING: placebo killer #FOAMed https://t.co/1hngwSMy0n
Nocebo effects with antidepressant clinical drug trial placebos. - PubMed - NCBI https://t.co/UScT9Pi3Eb
Nocebo effects with antidepressant clinical drug trial placebos. - PubMed - NCBI https://t.co/9KXYYs5vpg
Nocebo effects with antidepressant clinical drug trial placebos https://t.co/Bc2begkC21
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