'The frailty of adaptive hypotheses for the origins of organismal complexity' by Michael Lynch (2007) https://t.co/fTJk0sNAFY "the litmus test for any evolutionary hypothesis must be its consistency with fundamental population-genetic principles" https://t.co/bUb1PzBkDc
The frailty of adaptive hypotheses for the origins of organismal complexity.
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Oct 2019 – Sep 2025Where it's discussed
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Overall, these discussions reflect strong agreement with Lynch's critique, citing detailed evidence like Lynch’s emphasis on drift and population genetics, and referencing educational videos to deepen understanding. The tone is analytical and supportive, emphasizing the article's importance in challenging traditional adaptive explanations for organismal complexity.
Most discussions acknowledge and support the critique of adaptive hypotheses, emphasizing the importance of nonadaptive mechanisms like genetic drift, with references to Lynch's work reinforcing consensus.
Participants show high interest, engaging with detailed concepts such as population genetics and evolutionary theory, and referencing specific papers and videos.
Several discussants actively analyze the article's implications, citing examples like Lynch’s 2007 critique, and referencing external videos, indicating deep engagement.
The discussions highlight a significant impact on understanding evolutionary processes, with many considering the article’s critique as foundational for future research in evolutionary biology.
Abstract in brief
- The traditional view that evolution mainly occurs through adaptive processes is being challenged by new genetic and genomic research, which shows that nonadaptive forces like genetic drift and mutation also play a significant role in shaping biological complexity.
- Biological features such as organismal complexity, modularity, and evolvability may not be directly selected for but could instead be byproducts of underlying nonadaptive processes operating at lower levels of biological organization.
- The article suggests that many aspects of biological diversity—ranging from gene structure to phenotypic traits—may have origins rooted in nonadaptive mechanisms, with population genetic factors guiding the pathways that evolution can take.
Top posts
Most liked on X and BlueskyI really enjoyed this informative video by @zachbbionerd about the history of the Modern Synthesis, its relationship to evolutionary theory at large, what "gene centrism" is (and is not!) and claims that evolutionary biology is a field in crisis: https://t.co/3K2o7q1ZWf
Word https://t.co/QAZly8muzg
Population geneticist Mike Lynch - one of the strongest and best proponents of Neutral Theory - have made exactly this point in this famous and rethorical masterpiece from 2007: https://t.co/3rtmQZyMuF 8/
Not only that but it only operates on the additive component of allele effects. @kohn_gregory @Oliver_S_Curry @DialecticBio This topic is dealt with beautifully and harshly by Michael Lynch in his classic Frailty paper. https://t.co/OlNWxxEW9y You have to understand popgen! https://t.co/4MqCPlfQX1 https://t.co/YMYM7mJU44
Habla!
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@adam_kranz I like these two papers https://t.co/WIm1wwRAgD https://t.co/2iSbI93sm6
@CostelloWilliam @munecatmusic @datepsych Did/could you address this? Because I think it's a super fair critique https://t.co/eeYrwKTMY5
@cloisteredoystr @TheHistoryGuy07 Lynch is not saying they can't explain complexity, he's saying it's explained primarily by nonadaptive mechanisms like genetic drift. See: https://t.co/Hmx6VrOWI8 Gould is not saying we don't see evolutionary change in rocks, and he's not saying we're just trying to get rid...
RT @DialecticBio: 'The frailty of adaptive hypotheses for the origins of organismal complexity' by Michael Lynch (2007) https://t.co/fTJk0s…
RT @CoelhoPre: Habla!
Habla!
Hi @RichardDawkins! What do you think about this article? https://t.co/0gBFjV9t0Z
Halo @ProfDavidBuss ! What do you think on this paper? The frailty of adaptive hypotheses for the origins of organismal complexity https://t.co/cGy2XenY6J
Pendapatmu sama paper ini gimana bang @kamentrader ? Terkait kritik (salah satunya) terhadap evo psych yg terlalu adaptationism. The frailty of adaptive hypotheses for the origins of organismal complexity https://t.co/JsmKHSnW4Y
@primalpoly @sentientist @ProfDavidBuss Any thoughts on this? The frailty of adaptive hypotheses for the origins of organismal complexity https://t.co/0gBFjV9t0Z
@primalpoly @sentientist @ProfDavidBuss The frailty of adaptive hypotheses for the origins of organismal complexity https://t.co/0gBFjV9t0Z
I think the genuine critiques on EvoPsych has been the adaptive hypotheses. https://t.co/jSxBWz9AvZ The frailty of adaptive hypotheses for the origins of organismal complexity https://t.co/0gBFjV9t0Z What do you guys think? @primalpoly @sentientist @datepsych
@jarlebreivik @KasperKepp Agree with @KasperKepp and here is a classic criticism of naive adaptationism from a population geneticist (Mike Lynch) using Neutral Theory as a point of departure: https://t.co/1P6vefZasT
Population geneticist Mike Lynch - one of the strongest and best proponents of Neutral Theory - have made exactly this point in this famous and rethorical masterpiece from 2007: https://t.co/3rtmQZyMuF 8/
https://t.co/Bzcu7QHaAD https://t.co/v8lDIRXJ9p
Biologist Zach Hancock explains this quite well in this video: https://t.co/auNbKpL77v
@Texas_Thomist I have the perfect video for you, that clears up much of the confusion about that. And it's surely a much better source than a creationists website like that. https://t.co/VBQSgOmboO
RT @EvolOdonata: I really enjoyed this informative video by @zachbbionerd about the history of the Modern Synthesis, its relationship to ev…
@petepango Population genetics is full of mathematical models - confirmed both in the lab and in the wild. https://t.co/Yq1XvrT7rD
@zachbbionerd that's a winning semantic formula: any critique of "Mod Synthesis" is dismissed bc MS is a "historical period" not a crique-able theory (but explain that to Futuyma!!) every discarded orthodoxy is dubbed a "narrative" not a "theory" 1/? https://t.co/Fe5DzFZJrX
RT @EvolOdonata: I really enjoyed this informative video by @zachbbionerd about the history of the Modern Synthesis, its relationship to ev…
DEI? Affirmative Action? What Happens When Social Trends? Collide With Natural Selection? Thinning the Herd? https://t.co/AvFnyNi3qp
@heptaglemious @MeMaraCass @ScientiaPercept @KennethJOath @penguinteamsix @Will_D_Fi @Zeldrin7485 @hauxton @ForrestRichardA @REPENTHELLFIRE @MichaelBarisoh1 @erikwithoutaC @Micahwitz142858 @SteveTiger999 @bolt_carl @Paleoguy073 @SpudEternal @WC_Philosphy @TakethatCt @SecularSmurf @paddy_omalley @Simple_Shaman @grego74545 @of_hate65489 @MartinJBern @Kitty71052501 @Call_Me_Emo1 @DavidCamham1 @ArkEncounter @BioLogosOrg Mara might want to listen to @zachbbionerd's splendid summary of the development of modern evolutionary theory https://t.co/bgi2eefA1V. Dozens of science papers are alluded to along the way, most of which are available open access (as I know by downloading them).
RT @ras_nielsen: Word https://t.co/QAZly8muzg
RT @RJDownard: @zachbbionerd excellent video on “Is Evolution a Theory in Crisis?” https://t.co/bgi2eefA1V (Spoiler Alert: NO, it isn't
Is Evolution a Theory in Crisis? https://t.co/mCPPjC8tet via @YouTube
RT @RJDownard: @zachbbionerd excellent video on “Is Evolution a Theory in Crisis?” https://t.co/bgi2eefA1V (Spoiler Alert: NO, it isn't
RT @EvolOdonata: I really enjoyed this informative video by @zachbbionerd about the history of the Modern Synthesis, its relationship to ev…
RT @EvolOdonata: I really enjoyed this informative video by @zachbbionerd about the history of the Modern Synthesis, its relationship to ev…
@zachbbionerd excellent video on “Is Evolution a Theory in Crisis?” https://t.co/bgi2eefA1V (Spoiler Alert: NO, it isn't
RT @EvolOdonata: I really enjoyed this informative video by @zachbbionerd about the history of the Modern Synthesis, its relationship to ev…
Is Evolution a Theory in Crisis? [video] https://t.co/EXcJ5f9t0A
RT @StatedClearly: This new vid by @zachbbionerd is hard-lined but excellent! I'd love to see some @EES_update folks make a clear, honest r…
RT @EvolOdonata: I really enjoyed this informative video by @zachbbionerd about the history of the Modern Synthesis, its relationship to ev…
RT @EvolOdonata: I really enjoyed this informative video by @zachbbionerd about the history of the Modern Synthesis, its relationship to ev…
RT @EvolOdonata: I really enjoyed this informative video by @zachbbionerd about the history of the Modern Synthesis, its relationship to ev…
RT @EvolOdonata: I really enjoyed this informative video by @zachbbionerd about the history of the Modern Synthesis, its relationship to ev…
This new vid by @zachbbionerd is hard-lined but excellent! I'd love to see some @EES_update folks make a clear, honest rebuttal. Note the words "clear" and "honest". No more petty misrepresentations, please! https://t.co/AZQ4NNi9yU
RT @theevilutionist: Great video from @zachbbionerd that everyone should watch: https://t.co/S8MmggPwUD
RT @EvolOdonata: I really enjoyed this informative video by @zachbbionerd about the history of the Modern Synthesis, its relationship to ev…
I really enjoyed this informative video by @zachbbionerd about the history of the Modern Synthesis, its relationship to evolutionary theory at large, what "gene centrism" is (and is not!) and claims that evolutionary biology is a field in crisis: https://t.co/3K2o7q1ZWf
RT @theevilutionist: Great video from @zachbbionerd that everyone should watch: https://t.co/S8MmggPwUD
Great video from @zachbbionerd that everyone should watch: https://t.co/S8MmggPwUD
RT @ras_nielsen: Word https://t.co/QAZly8muzg
RT @ras_nielsen: Word https://t.co/QAZly8muzg
RT @ras_nielsen: Word https://t.co/QAZly8muzg
RT @ras_nielsen: Word https://t.co/QAZly8muzg
Word https://t.co/QAZly8muzg
Another excellent video by @zachbbionerd - Is Evolution a Theory in Crisis? https://t.co/u8T9ImTwSa
@datepsych Any opinion on these? https://t.co/T6LFkALtuH https://t.co/XS5Y9UOOSF
@EzequielPabloE @datepsych What is your opinion on this? https://t.co/T6LFkALtuH https://t.co/XS5Y9UOOSF (the journal isn't necessarily a critique on EP)
"There are no abrupt transitions in aspects of genomic architecture or gene structure between unicellular and multicellular species, nor between viruses, prokaryotes, and eukaryotes." https://t.co/Mtg849YAd7
16/ Quelques lectures remettant en cause l'ultra-adaptationnisme de l'Evopsy (et de SDebove): https://t.co/HGpszJNHcK https://t.co/pNx4vLlfDE https://t.co/EcrdoygLYY
See Michael Lynch’s beautiful diatribe in 2007: https://t.co/iXjXXOYu5r https://t.co/LjtownkOZm https://t.co/F7C4ArXJvU
RT @robwilliamsiii: Not only that but it only operates on the additive component of allele effects. @kohn_gregory @Oliver_S_Curry @Dialecti…
@DrYohanJohn This is not holism versus reductionism. This is “understands quantitative genetics and population genetics” versus blowing hot evodevo air. https://t.co/OlNWxxX5nG https://t.co/5jYPpxHQFD
RT @robwilliamsiii: Lots of books have been written by very smart developmental biologist who are unfortunately clueless about population g…
Lots of books have been written by very smart developmental biologist who are unfortunately clueless about population genetics. Lynch provides the clarity and critique that they need. He is harsh but entirely on the mark. https://t.co/OlNWxxX5nG https://t.co/hXSKaKVeme https://t.co/efxhrtI0pD
Because he has not taken the time to think through the fundamentals of population genetics. Read Lynch! https://t.co/OlNWxxX5nG https://t.co/jhrlSTqyWD https://t.co/xxqenJnt3W
Not only that but it only operates on the additive component of allele effects. @kohn_gregory @Oliver_S_Curry @DialecticBio This topic is dealt with beautifully and harshly by Michael Lynch in his classic Frailty paper. https://t.co/OlNWxxEW9y You have to understand popgen! https://t.co/4MqCPlfQX1 https://t.co/YMYM7mJU44
@rmp033 @OneOnOne1162 @gunsnrosesgirl3 Please read the original review if you are interested and the one specific population genetics link https://t.co/oNfxnonyGO Twitter is horrible for this. Good day.
RT @robwilliamsiii: Luiz, as Mike Lynch says: “Nothing in evolution makes sense except in light of population genetics”. Mike was at Bloomi…
Luiz, as Mike Lynch says: “Nothing in evolution makes sense except in light of population genetics”. Mike was at Bloomington so he should have left a big mark. Is there any population genetics in this thought piece? https://t.co/OlNWxxWxy8 https://t.co/Rx18F4Jr6e https://t.co/aRbOfBkBLn
RT @robwilliamsiii: Nicole: you mean the teleology bit? Yeh that gets a deservedly bad rap in most cases. Much of evolutionary biology is j…
Nicole: you mean the teleology bit? Yeh that gets a deservedly bad rap in most cases. Much of evolutionary biology is just-so stories on adaptation and selection. Michael Lynch has a fabulous rant on this in PNAS in 2007 that is well worth reading. 1/2 https://t.co/OlNWxxWxy8 https://t.co/IlVOwGM2qQ
RT @DialecticBio: 'The frailty of adaptive hypotheses for the origins of organismal complexity' by Michael Lynch (2007) https://t.co/fTJk0s…
RT @DialecticBio: 'The frailty of adaptive hypotheses for the origins of organismal complexity' by Michael Lynch (2007) https://t.co/fTJk0s…
RT @DialecticBio: 'The frailty of adaptive hypotheses for the origins of organismal complexity' by Michael Lynch (2007) https://t.co/fTJk0s…
RT @DialecticBio: 'The frailty of adaptive hypotheses for the origins of organismal complexity' by Michael Lynch (2007) https://t.co/fTJk0s…
RT @DialecticBio: 'The frailty of adaptive hypotheses for the origins of organismal complexity' by Michael Lynch (2007) https://t.co/fTJk0s…
RT @DialecticBio: 'The frailty of adaptive hypotheses for the origins of organismal complexity' by Michael Lynch (2007) https://t.co/fTJk0s…
RT @DialecticBio: 'The frailty of adaptive hypotheses for the origins of organismal complexity' by Michael Lynch (2007) https://t.co/fTJk0s…
RT @DialecticBio: 'The frailty of adaptive hypotheses for the origins of organismal complexity' by Michael Lynch (2007) https://t.co/fTJk0s…
RT @DialecticBio: 'The frailty of adaptive hypotheses for the origins of organismal complexity' by Michael Lynch (2007) https://t.co/fTJk0s…
RT @DialecticBio: 'The frailty of adaptive hypotheses for the origins of organismal complexity' by Michael Lynch (2007) https://t.co/fTJk0s…
RT @DialecticBio: 'The frailty of adaptive hypotheses for the origins of organismal complexity' by Michael Lynch (2007) https://t.co/fTJk0s…
'The frailty of adaptive hypotheses for the origins of organismal complexity' by Michael Lynch (2007) https://t.co/fTJk0sNAFY "the litmus test for any evolutionary hypothesis must be its consistency with fundamental population-genetic principles" https://t.co/bUb1PzBkDc
@leafs_s @systems_neuro Work like this would be improved by a foundation in quantitative population genetics. Drift dominates when effective population sizes are so very low. Have a look at this harsh but right commentary by Michael Lynch to see the risks: https://t.co/OlNWxxWxy8
@sientifiko1 Salvo algunos detalles, yo aquí estoy con Michael Lynch. https://t.co/mtKeC42MkA https://t.co/ZcqOStGsCh
way of base. Have a read of his harsh “Frailty” paper https://t.co/OlNWxxWxy8 or similar “Genomefart” chapter in Origins of Genome Architecture (which you will enjoy). or this more recent paper https://t.co/GKAvJHPx0E https://t.co/926wEgDeTH
Drift, drift, drift! Effective population size in all metazoans is low. Much, perhaps most, metazoan change is driven by drift. Read this edgy piece by Michael Lynch—maestro of popgen: https://t.co/OlNWxxWxy8 @WiringTheBrain But as Mike points out we all want cute stories. https://t.co/BJK9awM4R1 https://t.co/AmpxBDgNcL
emphasize the importance of drift in metazoan evolution. Effective population size of metazoans is surprisingly low and much change driven by chance fixation rather than strong selection. Does drift count as cause? Here is Mike’s biting PNAS paper. https://t.co/OlNWxxWxy8
"Who hurt you?" was my main question at the end of this paper. The lone author is clearly working out some stuff, with lines like, "The field of pop gen is technically demanding, and it is well known that most biologists abhor all things mathematical." https://t.co/jh6o4Bg4hy
RT @robwilliamsiii: "Nothing in evolution makes sense except in light of population genetics." Mike Lynch sent me this great paper I had mi…
"Nothing in evolution makes sense except in light of population genetics." Mike Lynch sent me this great paper I had missed (PNAS 2007) "The frailty of adaptive hypotheses for the origins of organismal complexity" Required reading for those in evo-devo. https://t.co/RgMKiusqle
The frailty of adaptive hypotheses for the origins of organismal complexity, Michael Lynch, 2007 https://t.co/TfnUMztv6j #進化論 #リチャード・ドーキンス #遺伝的浮動
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