May 2007 PMID 17494740

The frailty of adaptive hypotheses for the origins of organismal complexity.

Michael Lynch

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Mentions

137
Peak: 34 in Jan 2024
across 6 sources since Oct 2019

Extended reach

896,564
potential audience

Total likes

22,618

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741,984

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Oct 2019 – Sep 2025

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AI synopsis

What people are saying

Overall, these discussions reflect strong agreement with Lynch's critique, citing detailed evidence like Lynch’s emphasis on drift and population genetics, and referencing educational videos to deepen understanding. The tone is analytical and supportive, emphasizing the article's importance in challenging traditional adaptive explanations for organismal complexity.

AgreementStrong agreement

Most discussions acknowledge and support the critique of adaptive hypotheses, emphasizing the importance of nonadaptive mechanisms like genetic drift, with references to Lynch's work reinforcing consensus.

InterestHigh interest

Participants show high interest, engaging with detailed concepts such as population genetics and evolutionary theory, and referencing specific papers and videos.

EngagementHigh engagement

Several discussants actively analyze the article's implications, citing examples like Lynch’s 2007 critique, and referencing external videos, indicating deep engagement.

ImpactHigh impact

The discussions highlight a significant impact on understanding evolutionary processes, with many considering the article’s critique as foundational for future research in evolutionary biology.

Abstract in brief

  • The traditional view that evolution mainly occurs through adaptive processes is being challenged by new genetic and genomic research, which shows that nonadaptive forces like genetic drift and mutation also play a significant role in shaping biological complexity.
  • Biological features such as organismal complexity, modularity, and evolvability may not be directly selected for but could instead be byproducts of underlying nonadaptive processes operating at lower levels of biological organization.
  • The article suggests that many aspects of biological diversity—ranging from gene structure to phenotypic traits—may have origins rooted in nonadaptive mechanisms, with population genetic factors guiding the pathways that evolution can take.

Top posts

Most liked on X and Bluesky
dialecticbio.bsky.social
@DialecticBio · X

'The frailty of adaptive hypotheses for the origins of organismal complexity' by Michael Lynch (2007) https://t.co/fTJk0sNAFY "the litmus test for any evolutionary hypothesis must be its consistency with fundamental population-genetic principles" https://t.co/bUb1PzBkDc

Aug 27, 2022 · 84 likes · 15 shares · 5,255 followers View post →
Erik Svensson
@EvolOdonata · X

I really enjoyed this informative video by @zachbbionerd about the history of the Modern Synthesis, its relationship to evolutionary theory at large, what "gene centrism" is (and is not!) and claims that evolutionary biology is a field in crisis: https://t.co/3K2o7q1ZWf

Jan 3, 2024 · 51 likes · 11 shares · 7,904 followers View post →
Rasmus Nielsen
@ras_nielsen · X

Word https://t.co/QAZly8muzg

Jan 2, 2024 · 14 likes · 5 shares · 7,184 followers View post →
Erik Svensson
@EvolOdonata · X

Population geneticist Mike Lynch - one of the strongest and best proponents of Neutral Theory - have made exactly this point in this famous and rethorical masterpiece from 2007: https://t.co/3rtmQZyMuF 8/

Apr 7, 2024 · 6 likes · 7,921 followers View post →
Robert W. Williams
@robwilliamsiii · X

Not only that but it only operates on the additive component of allele effects. @kohn_gregory @Oliver_S_Curry @DialecticBio This topic is dealt with beautifully and harshly by Michael Lynch in his classic Frailty paper. https://t.co/OlNWxxEW9y You have to understand popgen! https://t.co/4MqCPlfQX1 https://t.co/YMYM7mJU44

Oct 10, 2022 · 6 likes · 1 share · 1,196 followers View post →
João
@CoelhoPre · X

Habla!

Jul 23, 2024 · 5 likes · 1 share · 2,628 followers View post →

All mentions

Qivshi
@Qivshi1 · X

@adam_kranz I like these two papers https://t.co/WIm1wwRAgD https://t.co/2iSbI93sm6

Sep 17, 2025 · 910 followers View post →
Has Israel Won the War Yet?
@FreiyaGreat · X

@CostelloWilliam @munecatmusic @datepsych Did/could you address this? Because I think it's a super fair critique https://t.co/eeYrwKTMY5

Mar 20, 2025 · 52 followers View post →
Finn Wilson
@FinnWilson9 · X

@cloisteredoystr @TheHistoryGuy07 Lynch is not saying they can't explain complexity, he's saying it's explained primarily by nonadaptive mechanisms like genetic drift. See: https://t.co/Hmx6VrOWI8 Gould is not saying we don't see evolutionary change in rocks, and he's not saying we're just trying to get rid...

Feb 2, 2025 · 142 followers View post →
Christopher John Lee
@JunHongLi56447 · X

RT @DialecticBio: 'The frailty of adaptive hypotheses for the origins of organismal complexity' by Michael Lynch (2007) https://t.co/fTJk0s…

Jan 2, 2025 · 15 shares · 133 followers View post →
Erik Svensson
@EvolOdonata · X

RT @CoelhoPre: Habla!

Jul 24, 2024 · 1 share · 7,921 followers View post →
João
@CoelhoPre · X

Habla!

Jul 23, 2024 · 5 likes · 1 share · 2,628 followers View post →
Has Israel Won the War Yet?
@FreiyaGreat · X

Hi @RichardDawkins! What do you think about this article? https://t.co/0gBFjV9t0Z

Jul 16, 2024 · 52 followers View post →
Has Israel Won the War Yet?
@FreiyaGreat · X

Halo @ProfDavidBuss ! What do you think on this paper? The frailty of adaptive hypotheses for the origins of organismal complexity https://t.co/cGy2XenY6J

May 30, 2024 · 52 followers View post →
Fahmi Assist
@FahmiAzizzzzz · X

Pendapatmu sama paper ini gimana bang @kamentrader ? Terkait kritik (salah satunya) terhadap evo psych yg terlalu adaptationism. The frailty of adaptive hypotheses for the origins of organismal complexity https://t.co/JsmKHSnW4Y

May 22, 2024 · 38 followers View post →
Has Israel Won the War Yet?
@FreiyaGreat · X

@primalpoly @sentientist @ProfDavidBuss Any thoughts on this? The frailty of adaptive hypotheses for the origins of organismal complexity https://t.co/0gBFjV9t0Z

May 20, 2024 · 52 followers View post →
Has Israel Won the War Yet?
@FreiyaGreat · X

@primalpoly @sentientist @ProfDavidBuss The frailty of adaptive hypotheses for the origins of organismal complexity https://t.co/0gBFjV9t0Z

May 20, 2024 · 52 followers View post →
Has Israel Won the War Yet?
@FreiyaGreat · X

I think the genuine critiques on EvoPsych has been the adaptive hypotheses. https://t.co/jSxBWz9AvZ The frailty of adaptive hypotheses for the origins of organismal complexity https://t.co/0gBFjV9t0Z What do you guys think? @primalpoly @sentientist @datepsych

May 20, 2024 · 52 followers View post →
Erik Svensson
@EvolOdonata · X

@jarlebreivik @KasperKepp Agree with @KasperKepp and here is a classic criticism of naive adaptationism from a population geneticist (Mike Lynch) using Neutral Theory as a point of departure: https://t.co/1P6vefZasT

Apr 20, 2024 · 7,921 followers View post →
Erik Svensson
@EvolOdonata · X

Population geneticist Mike Lynch - one of the strongest and best proponents of Neutral Theory - have made exactly this point in this famous and rethorical masterpiece from 2007: https://t.co/3rtmQZyMuF 8/

Apr 7, 2024 · 6 likes · 7,921 followers View post →
Sichu Lu
@lu_sichu · X

https://t.co/Bzcu7QHaAD https://t.co/v8lDIRXJ9p

Apr 3, 2024 · 2 likes · 3,578 followers View post →
Jackson Wheat
@JacksonWheat1 · X

Biologist Zach Hancock explains this quite well in this video: https://t.co/auNbKpL77v

Mar 31, 2024 · 2 likes · 2,854 followers View post →
Thomas Panzer
@tpawap · X

@Texas_Thomist I have the perfect video for you, that clears up much of the confusion about that. And it's surely a much better source than a creationists website like that. https://t.co/VBQSgOmboO

Jan 16, 2024 · 177 followers View post →
Luis Castañeda
@BioCastaneda · X

RT @EvolOdonata: I really enjoyed this informative video by @zachbbionerd about the history of the Modern Synthesis, its relationship to ev…

Jan 12, 2024 · 11 shares · 1,962 followers View post →
Thomas Panzer
@tpawap · X

@petepango Population genetics is full of mathematical models - confirmed both in the lab and in the wild. https://t.co/Yq1XvrT7rD

Jan 12, 2024 · 177 followers View post →
Arlin
@ArlinStoltzfus · X

@zachbbionerd that's a winning semantic formula: any critique of "Mod Synthesis" is dismissed bc MS is a "historical period" not a crique-able theory (but explain that to Futuyma!!) every discarded orthodoxy is dubbed a "narrative" not a "theory" 1/? https://t.co/Fe5DzFZJrX

Jan 11, 2024 · 2 likes · 878 followers View post →
Laurence Despres
@DespresLaurence · X

RT @EvolOdonata: I really enjoyed this informative video by @zachbbionerd about the history of the Modern Synthesis, its relationship to ev…

Jan 11, 2024 · 11 shares · 77 followers View post →
Kai Chiu
@KaiChiu1947 · X

DEI? Affirmative Action? What Happens When Social Trends? Collide With Natural Selection? Thinning the Herd? https://t.co/AvFnyNi3qp

Jan 10, 2024 · 118 followers View post →
Rulon James Downard
@RJDownard · X

@heptaglemious @MeMaraCass @ScientiaPercept @KennethJOath @penguinteamsix @Will_D_Fi @Zeldrin7485 @hauxton @ForrestRichardA @REPENTHELLFIRE @MichaelBarisoh1 @erikwithoutaC @Micahwitz142858 @SteveTiger999 @bolt_carl @Paleoguy073 @SpudEternal @WC_Philosphy @TakethatCt @SecularSmurf @paddy_omalley @Simple_Shaman @grego74545 @of_hate65489 @MartinJBern @Kitty71052501 @Call_Me_Emo1 @DavidCamham1 @ArkEncounter @BioLogosOrg Mara might want to listen to @zachbbionerd's splendid summary of the development of modern evolutionary theory https://t.co/bgi2eefA1V. Dozens of science papers are alluded to along the way, most of which are available open access (as I know by downloading them).

Jan 5, 2024 · 1 like · 3,581 followers View post →
Octavio S. Paulo
@OctavioSPaulo · X

RT @ras_nielsen: Word https://t.co/QAZly8muzg

Jan 5, 2024 · 5 shares · 398 followers View post →
Creationist Misconceptions
@_CROPES_ · X

RT @RJDownard: @zachbbionerd excellent video on “Is Evolution a Theory in Crisis?” https://t.co/bgi2eefA1V (Spoiler Alert: NO, it isn't

Jan 5, 2024 · 2 shares · 6,407 followers View post →
Nell Whiteside
@scividence · X

Is Evolution a Theory in Crisis? https://t.co/mCPPjC8tet via @YouTube

Jan 5, 2024 · 557 followers View post →
Pau Comes #RepúblicaCatalana
@paucomes · X

RT @RJDownard: @zachbbionerd excellent video on “Is Evolution a Theory in Crisis?” https://t.co/bgi2eefA1V (Spoiler Alert: NO, it isn't

Jan 5, 2024 · 2 shares · 4,818 followers View post →
Miguel Delgado
@MikkelD95 · X

RT @EvolOdonata: I really enjoyed this informative video by @zachbbionerd about the history of the Modern Synthesis, its relationship to ev…

Jan 5, 2024 · 11 shares · 6 followers View post →
Angela Nava Bolaños
@lunalegna · X

RT @EvolOdonata: I really enjoyed this informative video by @zachbbionerd about the history of the Modern Synthesis, its relationship to ev…

Jan 4, 2024 · 11 shares · 900 followers View post →
Rulon James Downard
@RJDownard · X

@zachbbionerd excellent video on “Is Evolution a Theory in Crisis?” https://t.co/bgi2eefA1V (Spoiler Alert: NO, it isn't

Jan 4, 2024 · 4 likes · 2 shares · 3,581 followers View post →
lil rodolith
@paleourodon · X

RT @EvolOdonata: I really enjoyed this informative video by @zachbbionerd about the history of the Modern Synthesis, its relationship to ev…

Jan 4, 2024 · 11 shares · 247 followers View post →
Gary Ritchison
@GaryRitchison · X

Is Evolution a Theory in Crisis? [video] https://t.co/EXcJ5f9t0A

Jan 4, 2024 · 318 followers View post →
Thomas Cabaret (thomascabaret84.bsky.social)
@ThomasCabaret84 · X

RT @StatedClearly: This new vid by @zachbbionerd is hard-lined but excellent! I'd love to see some @EES_update folks make a clear, honest r…

Jan 4, 2024 · 1 share · 4,942 followers View post →
Sebastian E. Ramos-Onsins
@SebasRamosO · X

RT @EvolOdonata: I really enjoyed this informative video by @zachbbionerd about the history of the Modern Synthesis, its relationship to ev…

Jan 4, 2024 · 11 shares · 80 followers View post →
Miguel Angel Contreras Sieck
@MiguelSieck · X

RT @EvolOdonata: I really enjoyed this informative video by @zachbbionerd about the history of the Modern Synthesis, its relationship to ev…

Jan 3, 2024 · 11 shares · 1,576 followers View post →
Hugo A. Benítez
@HugoBenitezd · X

RT @EvolOdonata: I really enjoyed this informative video by @zachbbionerd about the history of the Modern Synthesis, its relationship to ev…

Jan 3, 2024 · 11 shares · 2,447 followers View post →
Borja Milá
@borjamila · X

RT @EvolOdonata: I really enjoyed this informative video by @zachbbionerd about the history of the Modern Synthesis, its relationship to ev…

Jan 3, 2024 · 11 shares · 877 followers View post →
Stated Clearly - Jon Perry
@StatedClearly · X

This new vid by @zachbbionerd is hard-lined but excellent! I'd love to see some @EES_update folks make a clear, honest rebuttal. Note the words "clear" and "honest". No more petty misrepresentations, please! https://t.co/AZQ4NNi9yU

Jan 3, 2024 · 4 likes · 1 share · 4,557 followers View post →
Scott Duke
@free_thinker63 · X

RT @theevilutionist: Great video from @zachbbionerd that everyone should watch: https://t.co/S8MmggPwUD

Jan 3, 2024 · 2 shares · 98 followers View post →
Pouria Dasmeh
@PouriaDasmeh · X

RT @EvolOdonata: I really enjoyed this informative video by @zachbbionerd about the history of the Modern Synthesis, its relationship to ev…

Jan 3, 2024 · 11 shares · 123 followers View post →
Erik Svensson
@EvolOdonata · X

I really enjoyed this informative video by @zachbbionerd about the history of the Modern Synthesis, its relationship to evolutionary theory at large, what "gene centrism" is (and is not!) and claims that evolutionary biology is a field in crisis: https://t.co/3K2o7q1ZWf

Jan 3, 2024 · 51 likes · 11 shares · 7,904 followers View post →
Danish Debater
@DanishDebater · X

RT @theevilutionist: Great video from @zachbbionerd that everyone should watch: https://t.co/S8MmggPwUD

Jan 3, 2024 · 2 shares · 452 followers View post →
Creation Myths
@theevilutionist · X

Great video from @zachbbionerd that everyone should watch: https://t.co/S8MmggPwUD

Jan 3, 2024 · 5 likes · 2 shares · 734 followers View post →
Nicholas Price
@price_nich79506 · X

RT @ras_nielsen: Word https://t.co/QAZly8muzg

Jan 3, 2024 · 5 shares · 7 followers View post →
Stanislav Mihulka
@MihulkaS · X

RT @ras_nielsen: Word https://t.co/QAZly8muzg

Jan 3, 2024 · 5 shares · 2,956 followers View post →
Archaeogenomics UiO
@archaeogenomics · X

RT @ras_nielsen: Word https://t.co/QAZly8muzg

Jan 3, 2024 · 5 shares · 621 followers View post →
Elena Bosch
@ElenaBosch8 · X

RT @ras_nielsen: Word https://t.co/QAZly8muzg

Jan 3, 2024 · 5 shares · 222 followers View post →
Rasmus Nielsen
@ras_nielsen · X

Word https://t.co/QAZly8muzg

Jan 2, 2024 · 14 likes · 5 shares · 7,184 followers View post →
Alex Palazzo
@ribonucleicacid · X

Another excellent video by @zachbbionerd - Is Evolution a Theory in Crisis? https://t.co/u8T9ImTwSa

Jan 2, 2024 · 4 likes · 1,164 followers View post →
Has Israel Won the War Yet?
@FreiyaGreat · X

@datepsych Any opinion on these? https://t.co/T6LFkALtuH https://t.co/XS5Y9UOOSF

Dec 31, 2023 · 52 followers View post →
Has Israel Won the War Yet?
@FreiyaGreat · X

@EzequielPabloE @datepsych What is your opinion on this? https://t.co/T6LFkALtuH https://t.co/XS5Y9UOOSF (the journal isn't necessarily a critique on EP)

Dec 31, 2023 · 52 followers View post →
Denouncer of Everything
@searchingthru · X

"There are no abrupt transitions in aspects of genomic architecture or gene structure between unicellular and multicellular species, nor between viruses, prokaryotes, and eukaryotes." https://t.co/Mtg849YAd7

Feb 9, 2023 · 405 followers View post →
Lord Totoche
@Branquignol · X

16/ Quelques lectures remettant en cause l'ultra-adaptationnisme de l'Evopsy (et de SDebove): https://t.co/HGpszJNHcK https://t.co/pNx4vLlfDE https://t.co/EcrdoygLYY

Dec 8, 2022 · 292 followers View post →
Robert W. Williams
@robwilliamsiii · X

See Michael Lynch’s beautiful diatribe in 2007: https://t.co/iXjXXOYu5r https://t.co/LjtownkOZm https://t.co/F7C4ArXJvU

Oct 29, 2022 · 2 likes · 1,196 followers View post →
Miguel Angel Contreras Sieck
@MiguelSieck · X

RT @robwilliamsiii: Not only that but it only operates on the additive component of allele effects. @kohn_gregory @Oliver_S_Curry @Dialecti…

Oct 11, 2022 · 1 share · 1,569 followers View post →
Robert W. Williams
@robwilliamsiii · X

@DrYohanJohn This is not holism versus reductionism. This is “understands quantitative genetics and population genetics” versus blowing hot evodevo air. https://t.co/OlNWxxX5nG https://t.co/5jYPpxHQFD

Oct 10, 2022 · 1,196 followers View post →
Siji Oladeji
@Lightgang_ · X

RT @robwilliamsiii: Lots of books have been written by very smart developmental biologist who are unfortunately clueless about population g…

Oct 10, 2022 · 1 share · 2,665 followers View post →
Robert W. Williams
@robwilliamsiii · X

Lots of books have been written by very smart developmental biologist who are unfortunately clueless about population genetics. Lynch provides the clarity and critique that they need. He is harsh but entirely on the mark. https://t.co/OlNWxxX5nG https://t.co/hXSKaKVeme https://t.co/efxhrtI0pD

Oct 10, 2022 · 1 like · 1 share · 1,196 followers View post →
Robert W. Williams
@robwilliamsiii · X

Because he has not taken the time to think through the fundamentals of population genetics. Read Lynch! https://t.co/OlNWxxX5nG https://t.co/jhrlSTqyWD https://t.co/xxqenJnt3W

Oct 10, 2022 · 1,196 followers View post →
Robert W. Williams
@robwilliamsiii · X

Not only that but it only operates on the additive component of allele effects. @kohn_gregory @Oliver_S_Curry @DialecticBio This topic is dealt with beautifully and harshly by Michael Lynch in his classic Frailty paper. https://t.co/OlNWxxEW9y You have to understand popgen! https://t.co/4MqCPlfQX1 https://t.co/YMYM7mJU44

Oct 10, 2022 · 6 likes · 1 share · 1,196 followers View post →
Dodos Run Semi Wild
@DodosRun · X

@rmp033 @OneOnOne1162 @gunsnrosesgirl3 Please read the original review if you are interested and the one specific population genetics link https://t.co/oNfxnonyGO Twitter is horrible for this. Good day.

Oct 8, 2022 · 73 followers View post →
SCimPULSE Foundation
@ScimPulse · X

RT @robwilliamsiii: Luiz, as Mike Lynch says: “Nothing in evolution makes sense except in light of population genetics”. Mike was at Bloomi…

Sep 19, 2022 · 1 share · 149 followers View post →
Robert W. Williams
@robwilliamsiii · X

Luiz, as Mike Lynch says: “Nothing in evolution makes sense except in light of population genetics”. Mike was at Bloomington so he should have left a big mark. Is there any population genetics in this thought piece? https://t.co/OlNWxxWxy8 https://t.co/Rx18F4Jr6e https://t.co/aRbOfBkBLn

Sep 17, 2022 · 4 likes · 1 share · 1,196 followers View post →
Hywel Nicholas Arnold
@headinq · X

RT @robwilliamsiii: Nicole: you mean the teleology bit? Yeh that gets a deservedly bad rap in most cases. Much of evolutionary biology is j…

Sep 7, 2022 · 1 share · 178 followers View post →
Robert W. Williams
@robwilliamsiii · X

Nicole: you mean the teleology bit? Yeh that gets a deservedly bad rap in most cases. Much of evolutionary biology is just-so stories on adaptation and selection. Michael Lynch has a fabulous rant on this in PNAS in 2007 that is well worth reading. 1/2 https://t.co/OlNWxxWxy8 https://t.co/IlVOwGM2qQ

Sep 7, 2022 · 1 share · 1,196 followers View post →
Amanuel
@a_manifolder · X

RT @DialecticBio: 'The frailty of adaptive hypotheses for the origins of organismal complexity' by Michael Lynch (2007) https://t.co/fTJk0s…

Sep 3, 2022 · 15 shares · 328 followers View post →
Javs Castro
@JavsCastro · X

RT @DialecticBio: 'The frailty of adaptive hypotheses for the origins of organismal complexity' by Michael Lynch (2007) https://t.co/fTJk0s…

Aug 30, 2022 · 15 shares · 55 followers View post →
itati, atole de cereza|
@savanna_itati · X

RT @DialecticBio: 'The frailty of adaptive hypotheses for the origins of organismal complexity' by Michael Lynch (2007) https://t.co/fTJk0s…

Aug 29, 2022 · 15 shares · 10,657 followers View post →
Christopher Wheat
@ChrisWWheat · X

RT @DialecticBio: 'The frailty of adaptive hypotheses for the origins of organismal complexity' by Michael Lynch (2007) https://t.co/fTJk0s…

Aug 28, 2022 · 15 shares · 1,615 followers View post →
Chris Wallis
@wallischris10 · X

RT @DialecticBio: 'The frailty of adaptive hypotheses for the origins of organismal complexity' by Michael Lynch (2007) https://t.co/fTJk0s…

Aug 28, 2022 · 15 shares · 889 followers View post →
Jiajun Ngiam (JJ)
@ngiamjiajun · X

RT @DialecticBio: 'The frailty of adaptive hypotheses for the origins of organismal complexity' by Michael Lynch (2007) https://t.co/fTJk0s…

Aug 27, 2022 · 15 shares · 168 followers View post →
Nabi Eullmann
@Nabi_Eullmann · X

RT @DialecticBio: 'The frailty of adaptive hypotheses for the origins of organismal complexity' by Michael Lynch (2007) https://t.co/fTJk0s…

Aug 27, 2022 · 15 shares · 607 followers View post →
Miguel Angel Contreras Sieck
@MiguelSieck · X

RT @DialecticBio: 'The frailty of adaptive hypotheses for the origins of organismal complexity' by Michael Lynch (2007) https://t.co/fTJk0s…

Aug 27, 2022 · 15 shares · 1,569 followers View post →
Sergi Valverde
@svalver · X

RT @DialecticBio: 'The frailty of adaptive hypotheses for the origins of organismal complexity' by Michael Lynch (2007) https://t.co/fTJk0s…

Aug 27, 2022 · 15 shares · 3,372 followers View post →
Erik Svensson
@EvolOdonata · X

RT @DialecticBio: 'The frailty of adaptive hypotheses for the origins of organismal complexity' by Michael Lynch (2007) https://t.co/fTJk0s…

Aug 27, 2022 · 15 shares · 7,921 followers View post →
The Daily Lurker
@JimHenleyMusic · X

RT @DialecticBio: 'The frailty of adaptive hypotheses for the origins of organismal complexity' by Michael Lynch (2007) https://t.co/fTJk0s…

Aug 27, 2022 · 15 shares · 1,979 followers View post →
dialecticbio.bsky.social
@DialecticBio · X

'The frailty of adaptive hypotheses for the origins of organismal complexity' by Michael Lynch (2007) https://t.co/fTJk0sNAFY "the litmus test for any evolutionary hypothesis must be its consistency with fundamental population-genetic principles" https://t.co/bUb1PzBkDc

Aug 27, 2022 · 84 likes · 15 shares · 5,255 followers View post →
Robert W. Williams
@robwilliamsiii · X

@leafs_s @systems_neuro Work like this would be improved by a foundation in quantitative population genetics. Drift dominates when effective population sizes are so very low. Have a look at this harsh but right commentary by Michael Lynch to see the risks: https://t.co/OlNWxxWxy8

Jul 5, 2022 · 1 like · 1,196 followers View post →
OscarSilva@ecoevo.social
@OscardelaCroixS · X

@sientifiko1 Salvo algunos detalles, yo aquí estoy con Michael Lynch. https://t.co/mtKeC42MkA https://t.co/ZcqOStGsCh

Jul 5, 2022 · 424 followers View post →
Robert W. Williams
@robwilliamsiii · X

way of base. Have a read of his harsh “Frailty” paper https://t.co/OlNWxxWxy8 or similar “Genomefart” chapter in Origins of Genome Architecture (which you will enjoy). or this more recent paper https://t.co/GKAvJHPx0E https://t.co/926wEgDeTH

Jul 5, 2022 · 1 like · 1,196 followers View post →
Robert W. Williams
@robwilliamsiii · X

Drift, drift, drift! Effective population size in all metazoans is low. Much, perhaps most, metazoan change is driven by drift. Read this edgy piece by Michael Lynch—maestro of popgen: https://t.co/OlNWxxWxy8 @WiringTheBrain But as Mike points out we all want cute stories. https://t.co/BJK9awM4R1 https://t.co/AmpxBDgNcL

Jun 27, 2022 · 1,196 followers View post →
Robert W. Williams
@robwilliamsiii · X

emphasize the importance of drift in metazoan evolution. Effective population size of metazoans is surprisingly low and much change driven by chance fixation rather than strong selection. Does drift count as cause? Here is Mike’s biting PNAS paper. https://t.co/OlNWxxWxy8

Jun 23, 2022 · 1 like · 1,196 followers View post →
Annika Reads
@papersofnote · X

"Who hurt you?" was my main question at the end of this paper. The lone author is clearly working out some stuff, with lines like, "The field of pop gen is technically demanding, and it is well known that most biologists abhor all things mathematical." https://t.co/jh6o4Bg4hy

Mar 1, 2022 · 4 likes · 1,066 followers View post →
Gihan Jayasinghe - Find me on Bluesky
@GihanJaya · X

RT @robwilliamsiii: "Nothing in evolution makes sense except in light of population genetics." Mike Lynch sent me this great paper I had mi…

Apr 18, 2021 · 1 share · 248 followers View post →
Robert W. Williams
@robwilliamsiii · X

"Nothing in evolution makes sense except in light of population genetics." Mike Lynch sent me this great paper I had missed (PNAS 2007) "The frailty of adaptive hypotheses for the origins of organismal complexity" Required reading for those in evo-devo. https://t.co/RgMKiusqle

Apr 13, 2021 · 2 likes · 1 share · 1,196 followers View post →
ムギトン
@mkguytone · X

The frailty of adaptive hypotheses for the origins of organismal complexity, Michael Lynch, 2007 https://t.co/TfnUMztv6j #進化論 #リチャード・ドーキンス #遺伝的浮動

Oct 11, 2019 · 3,392 followers View post →