PLoS One May 2007 PMID 17520024

Resistance exercise reverses aging in human skeletal muscle.

Simon Melov, Mark A Tarnopolsky, Kenneth Beckman, Krysta Felkey, Alan Hubbard

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Mentions

201
Peak: 64 in Mar 2024
across 6 sources since Oct 2021

Extended reach

1,535,571
potential audience

Total likes

21,203

Video views

1,172,544

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Oct 2021 – Oct 2025

Where it's discussed

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AI synopsis

What people are saying

The discussions display a high level of agreement and interest, with various posts emphasizing the importance of resistance training for aging populations, such as 'Resistance Exercise Reverses Aging in Human Skeletal Muscle' and statements like 'lift weights and smash aging'. The tone is predominantly positive and motivational, with users highlighting the potential practical and health impacts of the study, indicating a collective recognition of its significance.

AgreementStrong agreement

Most discussions strongly support the findings, emphasizing resistance exercise as a method to reverse aspects of aging, using affirming words like 'reverses' and 'smash aging'.

InterestHigh interest

Participants show high curiosity and enthusiasm about the topic, frequently sharing motivational statements and emphasizing the significance of resistance training.

EngagementModerate engagement

Many posts reference specific methods, like lifting heavy and training durations, indicating a moderate level of detailed engagement, though not deeply analytical.

ImpactHigh impact

The recurring use of phrases like 'game changer' and calling resistance training 'health care' suggests that users believe this research could significantly influence health practices and perceptions about aging.

Top posts

Most liked on X and Bluesky
Strength For Life
@Strength4_Life · X

Mar 29, 2024 · 246 likes · 74 shares · 11,550 followers View post →
Agingdoc
@agingdoc1 · X

Resistance Exercise Reverses Aging in Human Skeletal Muscle https://t.co/uUABkJXWey “older adults show evidence of mitochondrial impairment and muscle weakness… partially reversed at the phenotypic level… reversed at the transcriptome level s/p 6 months resistance training.” https://t.co/NAJiciyLyb

Sep 19, 2022 · 38 likes · 11 shares · 42,372 followers View post →
john morley
@drjohnmorley · X

Resistance Exercise Reverses Aging in Human Skeletal Muscle https://t.co/DYkOLyTg56

Oct 14, 2021 · 15 likes · 6 shares · 8,305 followers View post →
Ben Greenfield
@bengreenfield · X

Resistance Exercise Reverses Aging in Human Skeletal Muscle (a.k.a., lifting heavy shit, one to two times a week keeps you young): https://t.co/jhXA5GnTnq https://t.co/WBXQUW5SNv

Oct 20, 2025 · 8 likes · 1 share · 95,081 followers View post →
Chris Martey
@ChrisMartey · X

More articles from @Strength4_Life's page:

Nov 10, 2021 · 4 likes · 2 shares · 2,657 followers View post →
John Morley
@Meddocslu · X

Resistance Exercise Reverses Aging in Human Skeletal Muscle https://t.co/Q9keznecTm

Oct 15, 2021 · 4 likes · 1,215 followers View post →

All mentions

Steve Watts
@stevewatts · X

RT @bengreenfield: Resistance Exercise Reverses Aging in Human Skeletal Muscle (a.k.a., lifting heavy shit, one to two times a week keeps y…

Oct 20, 2025 · 1 share · 1,044 followers View post →
Ben Greenfield
@bengreenfield · X

Resistance Exercise Reverses Aging in Human Skeletal Muscle (a.k.a., lifting heavy shit, one to two times a week keeps you young): https://t.co/jhXA5GnTnq https://t.co/WBXQUW5SNv

Oct 20, 2025 · 8 likes · 1 share · 95,081 followers View post →
Ben Greenfield
@bengreenfield · X

Resistance Exercise Reverses Aging in Human Skeletal Muscle (a.k.a., lifting heavy, shit, one to two times a week keeps you young): https://t.co/jhXA5GnTnq https://t.co/t5cHVTiM7T

Oct 20, 2025 · 3 likes · 95,081 followers View post →
AuroraBiteQuest
@AuroraBiteQuest · X

RT @Mangan150: Lift weights and smash aging. Resistance Exercise Reverses Aging in Human Skeletal Muscle https://t.co/n5qZlsVwnL

Aug 10, 2025 · 39 shares View post →
Dr. Gennadi Glinsky, MD, Ph.D.
@gglinskii · X

Resistance Exercise Reverses Aging in Human Skeletal Muscle https://t.co/h16OS4jcgS

Jul 8, 2025 · 2,061 followers View post →
Javed Alam
@jalam1001 · X

Title: Resistance Exercise Reverses Aging in Human Skeletal Muscle DOI: 10.1371/journal.pone.0000465 Summary: This study by Simon Melov et al. investigates the impact of resistance exercise on the gene expression profile of aging skeletal muscle. Researchers compared muscle https://t.co/tzXaXU5OjX

May 7, 2025 · 2 likes · 1,005 followers View post →
Javed Alam
@jalam1001 · X

Resistance training $$$$$$ Title: Resistance Exercise Reverses Aging in Human Skeletal Muscle DOI: 10.1371/journal.pone.0000465 Summary: This study by Simon Melov et al. investigates the impact of resistance exercise on the gene expression profile of aging skeletal muscle. https://t.co/Kdi9olx8lL

May 7, 2025 · 1 like · 1,005 followers View post →
Gordon Matthew
@gordonsky · X

@DrEenfeldt forgot the link https://t.co/QdoALccXdo

Jan 10, 2025 · 1 like · 24 followers View post →
DANVZLA
@danvzla · X

Resistance Exercise Reverses Aging in Human Skeletal Muscle | PLOS ONE https://t.co/cy4ZUHCJI6

Jan 1, 2025 · 738 followers View post →
Luciano Abba
@lucianoabba · X

Resistance Exercise Reverses Aging in Human Skeletal Muscle | PLOS ONE https://t.co/7Y1Cs3x4eh

Jan 1, 2025 · 1,422 followers View post →
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@docmaltese · X

RT @agingdoc1: Resistance Exercise Reverses Aging in Human Skeletal Muscle https://t.co/uUABkJXWey “older adults show evidence of mitocho…

Sep 19, 2022 · 11 shares · 1,787 followers View post →
Ivan Aprahamian
@IAprahamian · X

RT @agingdoc1: Resistance Exercise Reverses Aging in Human Skeletal Muscle https://t.co/uUABkJXWey “older adults show evidence of mitocho…

Sep 19, 2022 · 11 shares · 488 followers View post →
The Phoenix Lab
@The_Phoenix_Lab · X

RT @agingdoc1: Resistance Exercise Reverses Aging in Human Skeletal Muscle https://t.co/uUABkJXWey “older adults show evidence of mitocho…

Sep 19, 2022 · 11 shares · 212 followers View post →
ComunidadLongevidad
@Com_longevidad · X

RT @agingdoc1: Resistance Exercise Reverses Aging in Human Skeletal Muscle https://t.co/uUABkJXWey “older adults show evidence of mitocho…

Sep 19, 2022 · 11 shares · 16 followers View post →
Mind Your Science!
@MindYourSci · X

RT @agingdoc1: Resistance Exercise Reverses Aging in Human Skeletal Muscle https://t.co/uUABkJXWey “older adults show evidence of mitocho…

Sep 19, 2022 · 11 shares · 132 followers View post →
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@PaulRothweiler · X

RT @agingdoc1: Resistance Exercise Reverses Aging in Human Skeletal Muscle https://t.co/uUABkJXWey “older adults show evidence of mitocho…

Sep 19, 2022 · 11 shares · 18 followers View post →
2.0
@IrvineMadula · X

RT @agingdoc1: Resistance Exercise Reverses Aging in Human Skeletal Muscle https://t.co/uUABkJXWey “older adults show evidence of mitocho…

Sep 19, 2022 · 11 shares · 4,081 followers View post →
Alexander Dakhovnik
@ADakhovnik · X

RT @agingdoc1: Resistance Exercise Reverses Aging in Human Skeletal Muscle https://t.co/uUABkJXWey “older adults show evidence of mitocho…

Sep 19, 2022 · 11 shares · 78 followers View post →
Chrisk_ep
@CK_ExPhys · X

RT @agingdoc1: Resistance Exercise Reverses Aging in Human Skeletal Muscle https://t.co/uUABkJXWey “older adults show evidence of mitocho…

Sep 19, 2022 · 11 shares · 73 followers View post →
Shashi Iyengar | Accredited Metabolic Health Coach
@shashiiyengar · X

RT @agingdoc1: Resistance Exercise Reverses Aging in Human Skeletal Muscle https://t.co/uUABkJXWey “older adults show evidence of mitocho…

Sep 19, 2022 · 11 shares · 29,003 followers View post →
Agingdoc
@agingdoc1 · X

Resistance Exercise Reverses Aging in Human Skeletal Muscle https://t.co/uUABkJXWey “older adults show evidence of mitochondrial impairment and muscle weakness… partially reversed at the phenotypic level… reversed at the transcriptome level s/p 6 months resistance training.” https://t.co/NAJiciyLyb

Sep 19, 2022 · 38 likes · 11 shares · 42,372 followers View post →
John T Weatherly
@jtwheat27 · X

This was pub back in 2007. https://t.co/L7GbYU5WMM

Mar 14, 2022 · 5,031 followers View post →
Cindy Kugler
@Exspec85 · X

RT @ChrisMartey: More articles from @Strength4_Life's page:

Nov 10, 2021 · 2 shares · 232 followers View post →
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@SuzanneRIggs9 · X

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Nov 10, 2021 · 2 shares · 121 followers View post →
Chris Martey
@ChrisMartey · X

More articles from @Strength4_Life's page:

Nov 10, 2021 · 4 likes · 2 shares · 2,657 followers View post →
Sailesh Mishra
@sailesh2000 · X

RT @drjohnmorley: Resistance Exercise Reverses Aging in Human Skeletal Muscle https://t.co/DYkOLyTg56

Oct 15, 2021 · 6 shares · 3,148 followers View post →
John Morley
@Meddocslu · X

Resistance Exercise Reverses Aging in Human Skeletal Muscle https://t.co/Q9keznecTm

Oct 15, 2021 · 4 likes · 1,215 followers View post →
Olena Tomarevska
@tomarevskaya · X

RT @drjohnmorley: Resistance Exercise Reverses Aging in Human Skeletal Muscle https://t.co/DYkOLyTg56

Oct 15, 2021 · 6 shares · 338 followers View post →
nick
@strengthEP1 · X

RT @drjohnmorley: Resistance Exercise Reverses Aging in Human Skeletal Muscle https://t.co/DYkOLyTg56

Oct 14, 2021 · 6 shares · 62 followers View post →
Luis
@RoCo1796 · X

RT @drjohnmorley: Resistance Exercise Reverses Aging in Human Skeletal Muscle https://t.co/DYkOLyTg56

Oct 14, 2021 · 6 shares · 316 followers View post →
NaO
@spikeoutOXY · X

RT @drjohnmorley: Resistance Exercise Reverses Aging in Human Skeletal Muscle https://t.co/DYkOLyTg56

Oct 14, 2021 · 6 shares · 156 followers View post →
Gustavo Duque
@DrGustavoDuque · X

RT @drjohnmorley: Resistance Exercise Reverses Aging in Human Skeletal Muscle https://t.co/DYkOLyTg56

Oct 14, 2021 · 6 shares · 4,433 followers View post →
john morley
@drjohnmorley · X

Resistance Exercise Reverses Aging in Human Skeletal Muscle https://t.co/DYkOLyTg56

Oct 14, 2021 · 15 likes · 6 shares · 8,305 followers View post →
Deborah Koolbeck
@Koolbeck · X

RT @ExphysPhD: Resistance Exercise is Health Care! Resistance Exercise Reverses Aging in Human Skeletal Muscle ⁦@UCF_Kinesiology⁩ ⁦@ucfchps…

Oct 9, 2021 · 5 shares · 1,033 followers View post →
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@movementcarelab · X

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