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The discussions reflect a wide-ranging concern about propofol infusion syndrome, as evidenced by users highlighting specific side effects like bradycardia and metabolic acidosis. Phrases such as 'rare but dangerous' and mentions of clinical practices underscore a serious tone and an understanding of the potential consequences of prolonged propofol use. Additionally, some posts reference historical contexts, linking the syndrome to well-known cases, further enriching the discussion about its clinical relevance.
The majority of posts show a general acceptance of the information presented in the publication regarding propofol infusion syndrome.
There is a high level of curiosity surrounding the complications and implications of propofol use, as seen in diverse discussions among users.
While some posts merely mention the syndrome, many delve into specific side effects and clinical considerations, reflecting a moderate level of engagement.
There is a strong belief among participants that this publication could significantly influence clinical practices and awareness regarding the risks associated with propofol.
⚠️ Propofol leads to ⬆️ risk of ZINC deficiency via urine losses Add this to #Propofol adverse effects: - Propofol is Mitochondrial Toxin - Mixed in omega-6 lipid - Propofol associated w/ ⬆️ post-ICU weakness - Cx of Propofol-infusion syndrome ☠️ We have better choices! #MedEd https://t.co/zUs5vZkAYP
⚠️ Propofol leads to ⬆️ risk of ZINC deficiency via urine losses Add this to #Propofol adverse effects: - Propofol is Mitochondrial Toxin - Mixed in omega-6 lipid - Propofol associated w/ ⬆️ post-ICU weakness - Cx of Propofol-infusion syndrome ☠️ We have better choices! #FOAMcc https://t.co/bfUOYNG9tc
@Xand_mi I think this is the bigger monitoring tip - trigs from a pathophys perspective are not well linked to PRIS. We usually have other labs (anion gap, lactate, etc) to trigger you to think PRIS long before trigs would This is my favorite PRIS review article: https://t.co/sVJty7yiDw
@world_of_med1 Propofol infusion syndrome Discontinue Propfol and replace it with another sedation
@IhabFathiSulima Propofol, onset of action 30secs, duration 15mins, with apnea phases during induction, airway reflexes might be lost with reduced frc, ventilation support may be required. Can be used as tiva, icu sedation, radiology sedation and procedural, watch for propofol infusion syndrome
Propofol, known as the 'milk of anesthesia,' is widely used in operating rooms and ICUs. This video explains what propofol is, how it works, its advantages, and the potential risks, including Propofol Infusion Syndrome…
Propofol, the famous milk of anesthesia, is widely used in operating rooms and ICUs. This video explains how it works on the brain, its advantages and risks, including Propofol Infusion Syndrome, and why it remains a…
Propofol, the renowned milk of anesthesia, is widely used in surgery and ICU settings. This video explains what propofol is, how it works, its advantages such as smooth induction and fast recovery, and its risks…
We explore the rare but scary phenomena of propofol infusion syndrome (PRIS) and propylene glycol toxicity, with our favorite toxicologist Jerry Snow. icuscenarios.com/episode-92-p... #emimcc #medsky
RT @icuscenarios: We explore the rare but scary phenomena of propofol infusion syndrome (PRIS) and propylene glycol toxicity, with our favo…
RT @icuscenarios: We explore the rare but scary phenomena of propofol infusion syndrome (PRIS) and propylene glycol toxicity, with our favo…
We explore the rare but scary phenomena of propofol infusion syndrome (PRIS) and propylene glycol toxicity, with our favorite toxicologist Jerry Snow. https://t.co/qA8OVkMfS7 #medtwitter #FOAMcc #FOAMed #toxicology
RT @yaq_95: -للان الدواء ما اعتمد من Food and Drug Administration (FDA) ومازال تحت الدراسات ليكون احد الخيارات بدال propofol -بالنسبة لمرضى…
-للان الدواء ما اعتمد من Food and Drug Administration (FDA) ومازال تحت الدراسات ليكون احد الخيارات بدال propofol -بالنسبة لمرضى ICU للان لاتوجد دراسات كافية اذا بيسبب propofol infusion syndrome -قريب سعره من propofol الي حاب يقرا اكثر https://t.co/2zH8ealu5A
RT @Paul_Wischmeyer: ⚠️ Propofol leads to ⬆️ risk of ZINC deficiency via urine losses Add this to #Propofol adverse effects: - Propofol is…
@JamesLynchGTC @human_frozen_ @gforcetenn @DrMohammadIAdi1 @Amanda_M_Hunter @ann_poppy @bathmatt @caroline6a Upon further review, "midazolam infusion syndrome" appears sparingly in literature (e.g., Wikipedia citing a 2007 pediatric review), describing delayed arousal post-infusion, but it's not a standardized term like propofol infusion syndrome. No 2015 Smith et al. paper exists. ICU
RT @KnowMedBetter: @IhabFathiSulima Drug: Propofol – IV general anesthetic (“milk of amnesia”). Side effects: Hypotension, bradycardia, ap…
RT @sgjdoc: @IhabFathiSulima Great drug. But look up Propofol Infusion Syndrome (PRIS)… surprised nobody mentioned it!
@IhabFathiSulima Great drug. But look up Propofol Infusion Syndrome (PRIS)… surprised nobody mentioned it!
RT @KnowMedBetter: @IhabFathiSulima Drug: Propofol – IV general anesthetic (“milk of amnesia”). Side effects: Hypotension, bradycardia, ap…
@IhabFathiSulima Drug: Propofol – IV general anesthetic (“milk of amnesia”). Side effects: Hypotension, bradycardia, apnea, pain on injection, Propofol infusion syndrome (rare). Why famous: Rapid onset/recovery; linked to Michael Jackson’s death. If injected arterially: Severe pain → arterial
RT @Paul_Wischmeyer: ⚠️ Propofol leads to ⬆️ risk of ZINC deficiency via urine losses Add this to #Propofol adverse effects: - Propofol is…
RT @Paul_Wischmeyer: ⚠️ Propofol leads to ⬆️ risk of ZINC deficiency via urine losses Add this to #Propofol adverse effects: - Propofol is…
RT @Paul_Wischmeyer: ⚠️ Propofol leads to ⬆️ risk of ZINC deficiency via urine losses Add this to #Propofol adverse effects: - Propofol is…
RT @Paul_Wischmeyer: ⚠️ Propofol leads to ⬆️ risk of ZINC deficiency via urine losses Add this to #Propofol adverse effects: - Propofol is…
RT @Paul_Wischmeyer: ⚠️ Propofol leads to ⬆️ risk of ZINC deficiency via urine losses Add this to #Propofol adverse effects: - Propofol is…
RT @Paul_Wischmeyer: ⚠️ Propofol leads to ⬆️ risk of ZINC deficiency via urine losses Add this to #Propofol adverse effects: - Propofol is…
RT @Paul_Wischmeyer: ⚠️ Propofol leads to ⬆️ risk of ZINC deficiency via urine losses Add this to #Propofol adverse effects: - Propofol is…
RT @Paul_Wischmeyer: ⚠️ Propofol leads to ⬆️ risk of ZINC deficiency via urine losses Add this to #Propofol adverse effects: - Propofol is…
RT @Paul_Wischmeyer: ⚠️ Propofol leads to ⬆️ risk of ZINC deficiency via urine losses Add this to #Propofol adverse effects: - Propofol is…
RT @Paul_Wischmeyer: ⚠️ Propofol leads to ⬆️ risk of ZINC deficiency via urine losses Add this to #Propofol adverse effects: - Propofol is…
RT @Paul_Wischmeyer: ⚠️ Propofol leads to ⬆️ risk of ZINC deficiency via urine losses Add this to #Propofol adverse effects: - Propofol is…
RT @Paul_Wischmeyer: ⚠️ Propofol leads to ⬆️ risk of ZINC deficiency via urine losses Add this to #Propofol adverse effects: - Propofol is…
RT @Paul_Wischmeyer: ⚠️ Propofol leads to ⬆️ risk of ZINC deficiency via urine losses Add this to #Propofol adverse effects: - Propofol is…
⚠️ Propofol leads to ⬆️ risk of ZINC deficiency via urine losses Add this to #Propofol adverse effects: - Propofol is Mitochondrial Toxin - Mixed in omega-6 lipid - Propofol associated w/ ⬆️ post-ICU weakness - Cx of Propofol-infusion syndrome ☠️ We have better choices! #FOAMcc https://t.co/bfUOYNG9tc
@marvin_lule68 How do you approach managing refractory status epilepticus in a patient already on high-dose midazolam and ketamine infusions, but now developing propofol infusion syndrome?
@drkeithsiau Propofol infusion syndrome
@PiyushRala007
@DocDeezWhat @TakethatCt @WestsydeServer Please don't oversimplify what I say. But yes, stress, stress hormones and their effect on cytokines play a role. And I can't exclude that false diagnosis, hasty intubation, propofol infusion syndrome and other fatal WHO protocols played a role in the majority of deaths. Can you?
@DocDeezWhat @TakethatCt @WestsydeServer Coincidentally the same symptoms as a panic attack, after paranoid idiots convince people they were in a life threatening situation. Also totally coincidentally your virus kills the high risk group for stress death (and propofol infusion syndrome)?? Use your brain please! https://t.co/jCwSV5mIXu
RT @BJAJournals: Propofol infusion syndrome (PRIS) incidence and related symptoms in children: new retrospective analysis of a nationwide d…
RT @smithECGBlog: Circulation: Propofol Infusion Syndrome (PRIS): "uncouples oxidative phosphorylation, impairs mitochondria β-oxidation of…
RT @Anaes_Journal: This weeks #ClassicPaperFriday is a narrative review of propofol infusion syndrome from 2007. It has been cited 212 time…
@PiyushRala007
@drkeithsiau Propofol infusion syndrome
"Personalized dosing, fewer side effects." ✅ Matching drug doses to individual metabolism
RT @JusticesJustine: @IhabFathiSulima Propofol, onset of action 30secs, duration 15mins, with apnea phases during induction, airway reflexe…
@IhabFathiSulima Propofol, onset of action 30secs, duration 15mins, with apnea phases during induction, airway reflexes might be lost with reduced frc, ventilation support may be required. Can be used as tiva, icu sedation, radiology sedation and procedural, watch for propofol infusion syndrome
@IhabFathiSulima Propofol (“Milk of Amnesia”)
RT @AliMedic_:
Propofol infusion syndrome is rare but dangerous. What’s your protocol for long-term sedation with propofol?
RT @smithECGBlog: Circulation: Propofol Infusion Syndrome (PRIS): "uncouples oxidative phosphorylation, impairs mitochondria β-oxidation of…
Propofol infusion syndrome is rare but dangerous. How do you monitor for this in long cases requiring TIVA?
RT @DrAbdulAzizQaz1: @IhabFathiSulima @Doctors__squad @drkeithsiau @OGdukeneurosurg The propofol cause liver damage. Although propofol infu…
@IhabFathiSulima @Doctors__squad @drkeithsiau @OGdukeneurosurg The propofol cause liver damage. Although propofol infusion syndrome, a potentially fatal complication that may occur after prolonged administration of high doses (typically exceeding 48 h at > 5 mg·kg−1·hr −1), is a known cause of acute liver injury, propofol is generally ,
@DrAkhilX What drug-Diprivan aka propofol Side effects - anaphylaxis, anaphylactoid rxn, propofol infusion syndrome, bradycardia, asystole, cardiac arrest seizures, opisthotonus, pancreatitis, pulmonary edema phlebitis, thrombosis, renal tubular toxicity, unconsciousness, behavioral
RT @ihussain1i: @world_of_med1 Propofol infusion syndrome Discontinue Propfol and replace it with another sedation
@world_of_med1 Propofol infusion syndrome Discontinue Propfol and replace it with another sedation
RT @capsulas_de: Síndrome de propofol… Fuente: Propofol infusion syndrome: a structured literature review and analysis of published case r…
RT @capsulas_de: Síndrome de propofol… Fuente: Propofol infusion syndrome: a structured literature review and analysis of published case r…
RT @AliMedic_:
RT @AliMedic_:
RT @AliMedic_:
9/ Sedation
Join us for "Propofol Infusion Syndrome" by Dr. Muthukumar Vellaichamy on Dec 22!
@intensegasser @drmohansai We use fentanyl sir, propofol only if patient is agitated despite fenta. We avoid propofol owing to propofol infusion syndrome. Atrac infusion in ARDS ventilation.
@IM_Crit_ Propofol Infusion Syndrome?
RT @Paul_Wischmeyer: ⚠️ Propofol leads to ⬆️ risk of ZINC deficiency via urine losses Add this to #Propofol adverse effects: - Propofol is…
RT @Paul_Wischmeyer: ⚠️ Propofol leads to ⬆️ risk of ZINC deficiency via urine losses Add this to #Propofol adverse effects: - Propofol is…
RT @Paul_Wischmeyer: ⚠️ Propofol leads to ⬆️ risk of ZINC deficiency via urine losses Add this to #Propofol adverse effects: - Propofol is…
RT @Paul_Wischmeyer: ⚠️ Propofol leads to ⬆️ risk of ZINC deficiency via urine losses Add this to #Propofol adverse effects: - Propofol is…
RT @Paul_Wischmeyer: ⚠️ Propofol leads to ⬆️ risk of ZINC deficiency via urine losses Add this to #Propofol adverse effects: - Propofol is…
RT @Paul_Wischmeyer: ⚠️ Propofol leads to ⬆️ risk of ZINC deficiency via urine losses Add this to #Propofol adverse effects: - Propofol is…
RT @Paul_Wischmeyer: ⚠️ Propofol leads to ⬆️ risk of ZINC deficiency via urine losses Add this to #Propofol adverse effects: - Propofol is…
RT @Paul_Wischmeyer: ⚠️ Propofol leads to ⬆️ risk of ZINC deficiency via urine losses Add this to #Propofol adverse effects: - Propofol is…
RT @Paul_Wischmeyer: ⚠️ Propofol leads to ⬆️ risk of ZINC deficiency via urine losses Add this to #Propofol adverse effects: - Propofol is…
RT @Paul_Wischmeyer: ⚠️ Propofol leads to ⬆️ risk of ZINC deficiency via urine losses Add this to #Propofol adverse effects: - Propofol is…
RT @Paul_Wischmeyer: ⚠️ Propofol leads to ⬆️ risk of ZINC deficiency via urine losses Add this to #Propofol adverse effects: - Propofol is…
RT @Paul_Wischmeyer: ⚠️ Propofol leads to ⬆️ risk of ZINC deficiency via urine losses Add this to #Propofol adverse effects: - Propofol is…
RT @Paul_Wischmeyer: ⚠️ Propofol leads to ⬆️ risk of ZINC deficiency via urine losses Add this to #Propofol adverse effects: - Propofol is…
RT @Paul_Wischmeyer: ⚠️ Propofol leads to ⬆️ risk of ZINC deficiency via urine losses Add this to #Propofol adverse effects: - Propofol is…
RT @Paul_Wischmeyer: ⚠️ Propofol leads to ⬆️ risk of ZINC deficiency via urine losses Add this to #Propofol adverse effects: - Propofol is…
RT @Paul_Wischmeyer: ⚠️ Propofol leads to ⬆️ risk of ZINC deficiency via urine losses Add this to #Propofol adverse effects: - Propofol is…
RT @Paul_Wischmeyer: ⚠️ Propofol leads to ⬆️ risk of ZINC deficiency via urine losses Add this to #Propofol adverse effects: - Propofol is…
RT @Paul_Wischmeyer: ⚠️ Propofol leads to ⬆️ risk of ZINC deficiency via urine losses Add this to #Propofol adverse effects: - Propofol is…
RT @Paul_Wischmeyer: ⚠️ Propofol leads to ⬆️ risk of ZINC deficiency via urine losses Add this to #Propofol adverse effects: - Propofol is…
RT @Paul_Wischmeyer: ⚠️ Propofol leads to ⬆️ risk of ZINC deficiency via urine losses Add this to #Propofol adverse effects: - Propofol is…
RT @Paul_Wischmeyer: ⚠️ Propofol leads to ⬆️ risk of ZINC deficiency via urine losses Add this to #Propofol adverse effects: - Propofol is…
RT @Paul_Wischmeyer: ⚠️ Propofol leads to ⬆️ risk of ZINC deficiency via urine losses Add this to #Propofol adverse effects: - Propofol is…
RT @Paul_Wischmeyer: ⚠️ Propofol leads to ⬆️ risk of ZINC deficiency via urine losses Add this to #Propofol adverse effects: - Propofol is…
RT @Paul_Wischmeyer: ⚠️ Propofol leads to ⬆️ risk of ZINC deficiency via urine losses Add this to #Propofol adverse effects: - Propofol is…
RT @Paul_Wischmeyer: ⚠️ Propofol leads to ⬆️ risk of ZINC deficiency via urine losses Add this to #Propofol adverse effects: - Propofol is…
RT @Paul_Wischmeyer: ⚠️ Propofol leads to ⬆️ risk of ZINC deficiency via urine losses Add this to #Propofol adverse effects: - Propofol is…
RT @Paul_Wischmeyer: ⚠️ Propofol leads to ⬆️ risk of ZINC deficiency via urine losses Add this to #Propofol adverse effects: - Propofol is…
RT @Paul_Wischmeyer: ⚠️ Propofol leads to ⬆️ risk of ZINC deficiency via urine losses Add this to #Propofol adverse effects: - Propofol is…
RT @Paul_Wischmeyer: ⚠️ Propofol leads to ⬆️ risk of ZINC deficiency via urine losses Add this to #Propofol adverse effects: - Propofol is…
RT @Paul_Wischmeyer: ⚠️ Propofol leads to ⬆️ risk of ZINC deficiency via urine losses Add this to #Propofol adverse effects: - Propofol is…
RT @Paul_Wischmeyer: ⚠️ Propofol leads to ⬆️ risk of ZINC deficiency via urine losses Add this to #Propofol adverse effects: - Propofol is…
RT @Paul_Wischmeyer: ⚠️ Propofol leads to ⬆️ risk of ZINC deficiency via urine losses Add this to #Propofol adverse effects: - Propofol is…
RT @Paul_Wischmeyer: ⚠️ Propofol leads to ⬆️ risk of ZINC deficiency via urine losses Add this to #Propofol adverse effects: - Propofol is…
RT @Paul_Wischmeyer: ⚠️ Propofol leads to ⬆️ risk of ZINC deficiency via urine losses Add this to #Propofol adverse effects: - Propofol is…
RT @Paul_Wischmeyer: ⚠️ Propofol leads to ⬆️ risk of ZINC deficiency via urine losses Add this to #Propofol adverse effects: - Propofol is…
RT @Paul_Wischmeyer: ⚠️ Propofol leads to ⬆️ risk of ZINC deficiency via urine losses Add this to #Propofol adverse effects: - Propofol is…
⚠️ Propofol leads to ⬆️ risk of ZINC deficiency via urine losses Add this to #Propofol adverse effects: - Propofol is Mitochondrial Toxin - Mixed in omega-6 lipid - Propofol associated w/ ⬆️ post-ICU weakness - Cx of Propofol-infusion syndrome ☠️ We have better choices! #MedEd https://t.co/zUs5vZkAYP
Propofol infusion syndrome is the collective best guess for an elective procedure that went sideways...hard. That's a disease I don't want to see again.
Letter to editor Propofol infusion syndrome: Analysis of French pharmacovigilance and World Health Organization Pharmacovigilance (VigiBase®) databases from 2020 to 2023 em-consulte.com/article/1668... #Propofol #IntensiveCare #Pharmacovigilance
I think q48 hrs, but it might be q72 hours Incidentally, I think this allows us to avoid propofol infusion syndrome - which I’ve never seen here
Could this be one of the reasons Michael died…? Doctors help me out here my mind has theories! https://t.co/onGLBJZlQs
@Xand_mi I think this is the bigger monitoring tip - trigs from a pathophys perspective are not well linked to PRIS. We usually have other labs (anion gap, lactate, etc) to trigger you to think PRIS long before trigs would This is my favorite PRIS review article: https://t.co/sVJty7yiDw
Propofol Infusion Syndrome – ICM Case Summaries #FOAMed https://criticalcarenorthampton.wordpress.com/2016/11/11/propofol-infusion-syndrome-icm-case-summaries-foamed
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