It is classic (and freely accessible) review article friday here today. First up, Skeletal Muscle Fatigue: Cellular Mechanisms. By Allan, Lamb & Westerblad, 2007 Physiological Reviews. Cited >1300 times https://t.co/bCJ5vUybQ6
Skeletal muscle fatigue: cellular mechanisms.
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Mar 2019 – May 2025Where it's discussed
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X / Twitter18 posts
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The discussions highlight a general agreement on the importance of the publication, with many participants referencing detailed mechanisms like glycogen depletion and calcium release, and mentioning how the research informs sports science and muscle physiology; tone and word choice such as 'complete,' 'classic,' and 'must read' reflect high regard and interest.
Most posters express support or recognition of the significance of the publication and its findings.
The discussions demonstrate high curiosity and interest, referencing detailed mechanisms and related literature.
Participants show deep engagement by referencing specific methods, mechanisms, and personal educational experiences.
Many acknowledge the article's influence on understanding muscle fatigue and its relevance to sports and research, indicating moderate to high impact.
Abstract in brief
- Muscle fatigue occurs after repeated intense use, leading to decreased performance and changes in muscle properties such as ions, action potential, and metabolites.
- Traditional views focused on lactate and hydrogen ions impairing muscle function, but in mammals, other factors like ionic imbalances, calcium release issues from the sarcoplasmic reticulum, and reactive oxygen species are more significant contributors.
- Understanding muscle fatigue mechanisms is complex because they vary depending on activity, and most research is done on animal tissues; applying these findings to humans and diseases remains a major challenge.]
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Most liked on X and BlueskyIf there is a sport where understanding of muscle fatigue is crucial, that is @CrossFit . I suggest the classic by Allen and colleagues https://t.co/E0LUTOvQYf https://t.co/6qisIfyqfp
@DrMarkBurnley A series of tutorials with @jeannedekerle during my undergrad. She gave me some light reading (!): the Allen 2008 fatigue review. I didn’t understand much of it but I wanted to learn more about fatigue, so stayed to do my MSc with her. https://t.co/MS7amodYvH
@Toptimum_Perfor @HeWaHippo @Alan_Couzens @AndyBeetroot @DrMarkBurnley @peter__leo @JeroenSwart This intensity will indeed change over time, https://t.co/2h1KczOOyP because of fatigue (which is a huge area) but research suggest the 'largest' factor is probably glycogen depletion which causes inefficiencies in Ca+ handling - see https://t.co/8UPHjEn55n
@johngetstrong @JonMackey14 Even acidity has been questioned. Read on this section: Lactate and H+ https://t.co/6UyUb7DejG
Skeletal Muscle Fatigue: Cellular Mechanisms | Physiological Reviews https://t.co/0RsOQCS6U9
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This video explores how muscle fatigue occurs during intense exercise, focusing on cellular and molecular processes like calcium dysregulation, inorganic phosphate, and reactive oxygen species. It challenges common…
@johngetstrong @JonMackey14 Even acidity has been questioned. Read on this section: Lactate and H+ https://t.co/6UyUb7DejG
If there is a sport where understanding of muscle fatigue is crucial, that is @CrossFit . I suggest the classic by Allen and colleagues https://t.co/E0LUTOvQYf https://t.co/6qisIfyqfp
Varios mecanismos involucrados en la fatiga muscular periférica como: Acumulación de metabolitos Reducción del suministro de energía Estrés oxidativo Alteración en la liberación de calcio "Skeletal muscle fatigue: cellular mechanisms" - Allen DG, Lamb GD, Westerblad H. https://t.co/Cry84RlFjk
@Toptimum_Perfor @HeWaHippo @Alan_Couzens @AndyBeetroot @DrMarkBurnley @peter__leo @JeroenSwart This intensity will indeed change over time, https://t.co/2h1KczOOyP because of fatigue (which is a huge area) but research suggest the 'largest' factor is probably glycogen depletion which causes inefficiencies in Ca+ handling - see https://t.co/8UPHjEn55n
https://t.co/WtCCD9CcGv
RT @StephenSeiler: It is classic (and freely accessible) review article friday here today. First up, Skeletal Muscle Fatigue: Cellular Mec…
RT @StephenSeiler: It is classic (and freely accessible) review article friday here today. First up, Skeletal Muscle Fatigue: Cellular Mec…
RT @StephenSeiler: It is classic (and freely accessible) review article friday here today. First up, Skeletal Muscle Fatigue: Cellular Mec…
RT @StephenSeiler: It is classic (and freely accessible) review article friday here today. First up, Skeletal Muscle Fatigue: Cellular Mec…
It is classic (and freely accessible) review article friday here today. First up, Skeletal Muscle Fatigue: Cellular Mechanisms. By Allan, Lamb & Westerblad, 2007 Physiological Reviews. Cited >1300 times https://t.co/bCJ5vUybQ6
Um dos trabalhos mais completos que eu já li sobre fadiga. https://t.co/hN2pyZpExx
@DrMarkBurnley A series of tutorials with @jeannedekerle during my undergrad. She gave me some light reading (!): the Allen 2008 fatigue review. I didn’t understand much of it but I wanted to learn more about fatigue, so stayed to do my MSc with her. https://t.co/MS7amodYvH
https://t.co/3ilOsODCeo
@_PaulMorgan This is also very good: https://t.co/8UPHjEn55n
@RonGeorge_Dubai @peter__leo @JamiePringle @AndyBeetroot @DrMarkBurnley See https://t.co/8UPHjEn55n
Skeletal Muscle Fatigue: Cellular Mechanisms | Physiological Reviews https://t.co/0RsOQCS6U9
Artigos citados ontem na minha aula online https://t.co/9v9LRPf1kM https://t.co/UZrxYdpxhI https://t.co/XJ4ZTY9niq https://t.co/lP2ZRBRqD1 https://t.co/tgyyocIq89
Skeletal muscle fatigue: cellular mechanisms. - PubMed - NCBI https://t.co/2aksnFZziD
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