Proc Biol Sci June 2008 PMID 18353749

Revealing the paradox of drug reward in human evolution.

Roger J Sullivan, Edward H Hagen, Peter Hammerstein

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The discussions reflect a generally positive and inquisitive stance towards the article, with comments like 'Muy interesante' and 'super interesante' highlighting curiosity. Some posts explore the evolutionary basis of mental disorders and drug use, emphasizing the article's influence on understanding human nature and health, through words that convey fascination and relevance, although most responses are brief and focused on curiosity rather than deep analysis.

AgreementModerate agreement

Most discussions seem supportive or curious about the article's ideas, especially relating to evolutionary explanations for human behaviors.

InterestHigh interest

People show high interest, with many expressing curiosity about evolutionary perspectives and the implications for mental health and drug use.

EngagementModerate engagement

Participants delve into discussions of mental health, drug use, and evolutionary theory, indicating moderate attention and engagement.

ImpactModerate impact

The conversations suggest the topic has some influence, sparking curiosity and potential consideration of how evolutionary biology affects human behaviors.

Abstract in brief

The common neurobiological models suggest that drug use is driven by reward mechanisms, but most drugs are actually plant toxins that evolved to deter animals, creating a paradox in understanding why humans seek them.
Evidence from plant evolutionary ecology and genetics shows that humans and ancient hominids have been exposed to plant toxins throughout evolution, and our genes have been shaped by this, which complicates the idea that drug reward is purely about seeking reward and not about dealing with toxins.
Resolving this paradox may involve understanding that humans might have evolved strategies to counter or even exploit plant neurotoxins, and a combined ecological and neurobiological approach is needed to fully understand why humans seek out these substances.]

Read the full abstract

All mentions

Understanding the Human Attraction to Psychoactive Substances

We explore why humans are attracted to psychoactive drugs despite most being plant toxins evolved to deter animals, revealing a paradox in drug reward mechanisms and human evolution.

SciShow · Oct 24, 2019 3,047,969 views

Evolutionary Explanation for Mental Disorders and Drug Reward Paradox

Why haven't evolution eliminated mental disorders? This video explores possible advantages and evolutionary explanations, alongside the paradox of drug reward, showing how human exposure to plant toxins has shaped our…

CuriosaMente · Mar 27, 2022 545,271 views

Alex Hill

@alexlizhill · X

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Sep 27, 2022 · 1 like · 1,700 followers View post →

Carlos 3

@xarl3ia · X

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Aug 28, 2022 · 49 followers View post →

Loretitolinda

@Loretitolinda · X

RT @EdoBartolome: @Loretitolinda Le dejo un videíto muy weno

Jul 13, 2022 · 1 share · 16,844 followers View post →

Eduardo Bartolomé

@EdoBartolome · X

@Loretitolinda Le dejo un videíto muy weno

Jul 13, 2022 · 1 like · 1 share · 712 followers View post →

liliana garcia

@lilocediel · X

RT @JulianRuizRoa: Muy bacano este nuevo enfoque de las enfermedades mentales a partir de la medicina evolutiva. Do mental disorders have a…

Apr 5, 2022 · 1 share · 1,923 followers View post →

Gerardo Caldera

@gerardo_caldera · X

@vicGomez2000 https://t.co/60F2nfxg1n

Apr 4, 2022 · 1 like · 624 followers View post →

Darwin De La Encina

@Darwin_Encina · X

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Mar 31, 2022 · 1,102 followers View post →

Chochi

@Chochi____ · X

Los trastornos mentales tienen una explicación evolutiva? https://t.co/HSgQDyTLG4

Mar 30, 2022 · 1,968 followers View post →

Fernanda Avril

@Fer_Avril · X

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Mar 29, 2022 · 15 followers View post →

mugre

@pilaruca_ · X

RT @curiosamente: #NuevoVideo | ¿Los trastornos mentales tienen una explicación evolutiva?

Mar 29, 2022 · 6 shares · 146 followers View post →

Bran

@BryanDH22 · X

¿Los trastornos mentales tienen una explicación evolutiva? - CuriosaMent... https://t.co/KYZycjOH4E a través de @YouTube Por si les sirve a ustedes o a sus seres queridos o alquien que conozcan ;)

Mar 28, 2022 · 286 followers View post →

D@x¥$l@

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Mar 28, 2022 · 395 followers View post →

Luis García

@angelbladex · X

Muy interesante :O ¿Los trastornos mentales tienen una explicación evolutiva? Más en el vídeo https://t.co/1P5DnyupI0

Mar 28, 2022 · 1 like · 194 followers View post →

Álvarez-Arellano

@alvarez_arellan · X

Mar 27, 2022 · 62 followers View post →

Denio Chávez

@DenioChavez · X

RT @curiosamente: #NuevoVideo | ¿Los trastornos mentales tienen una explicación evolutiva?

Mar 27, 2022 · 6 shares · 38 followers View post →

ॐ Mafer ॐ

@mafermartinezd · X

Súper interesante https://t.co/6NN5Glmyna

Mar 27, 2022 · 390 followers View post →

Juan Brujo

@JuanDeDiosmerol · X

RT @curiosamente: #NuevoVideo | ¿Los trastornos mentales tienen una explicación evolutiva?

Mar 27, 2022 · 6 shares · 465 followers View post →

Javier Lacroix

@javierlacroix · X

RT @curiosamente: #NuevoVideo | ¿Los trastornos mentales tienen una explicación evolutiva?

Mar 27, 2022 · 6 shares · 738 followers View post →

AlfredOteíza 

@lualotes87 · X

Me gustó un video de YouTube: ¿Los trastornos mentales tienen una explicación evolutiva? - CuriosaMente 331 https://t.co/B4U4dTv450

Mar 27, 2022 · 316 followers View post →

Jámin Samuel Fernández

@jaminsamuel18 · X

¿Los trastornos mentales tienen una explicación evolutiva? - CuriosaMent... https://t.co/FVYMHslD4q a través de @YouTube

Mar 27, 2022 · 780 followers View post →

DoomGuy_69

@DoomGuy_69 · X

RT @curiosamente: #NuevoVideo | ¿Los trastornos mentales tienen una explicación evolutiva?

Mar 27, 2022 · 6 shares · 13,070 followers View post →

CuriosaMente

@curiosamente · X

#NuevoVideo | ¿Los trastornos mentales tienen una explicación evolutiva?

Mar 27, 2022 · 10 likes · 6 shares · 39,943 followers View post →

hanspy

@hanspij · X

RT @ADrugResearcher: Thanks for this @neufeldsd https://t.co/AKw6sphGPS

Mar 10, 2021 · 1 share · 762 followers View post →

Alex Betsos, Marquis de Réagent

@ADrugResearcher · X

Thanks for this @neufeldsd https://t.co/AKw6sphGPS

Mar 10, 2021 · 7 likes · 1 share · 3,737 followers View post →

Andrés De Bon Marche

@Jose_Andres_Mtz · X

El uso de drogas por los seres humanos esta vinculado generalmente a una respuesta placentera o un beneficio rápido, pero ¿y si realmente tenemos una necesidad biológica y evolutiva para usarlas? https://t.co/KGyIykOavK https://t.co/9pfXEndzrF

Dec 16, 2020 · 1,864 followers View post →

@bhijit

@Abhijit_A_ · X

@irinimalliaraki You may find useful, 'Revealing the paradox of drug reward in human evolution' https://t.co/PqEsMGKKbY

Sep 27, 2019 · 1,315 followers View post →

99%problems

@jay_james84 · X

Revealing the paradox of drug reward in human evolution | Proceedings of the Royal Society B: Biological Sciences https://t.co/jjNBv3pGmR

Apr 9, 2019 · 532 followers View post →

Revealing the paradox of drug reward in human evolution.

Mentions per month

Where it's discussed

What people are saying

Abstract in brief

Top posts

All mentions

Understanding the Human Attraction to Psychoactive Substances

Evolutionary Explanation for Mental Disorders and Drug Reward Paradox