June 2008 PMID 18539916

Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes.

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Mentions

43
Peak: 4 in Apr 2019
across 4 sources since Aug 2018

Extended reach

282,329
potential audience

Total likes

351

Video views

13,850

Mentions per month

Aug 2018 – Jul 2024

Where it's discussed

  • X / Twitter14 posts
  • Blogs14 articles
  • News10 articles
  • YouTube5 videos

AI synopsis

What people are saying

The discussion highlights the importance of the study in advancing understanding of glucose control and vascular outcomes, with posts discussing related trials like ADVANCE and emphasizing the microvascular benefits, as well as concerns about hypoglycemia. The tone combines technical references and recognition of ongoing debates, reflecting a high interest and engagement in the subject's clinical relevance.

AgreementModerate agreement

Most posts acknowledge the significance of the study, with some expressions supporting its findings on microvascular benefits.

InterestHigh interest

Discussions demonstrate a high level of interest, referencing related trials, study details, and implications for treatment, indicating engagement with the topic.

EngagementModerate engagement

Posts include references to additional studies, critique, and commentary, showing a moderate depth of engagement with the research methodology and clinical relevance.

ImpactModerate impact

The discussions emphasize the study’s implications for clinical practice and future research, but some posts focus more on background information and less on transformative impact.

Abstract in brief

  • Intensive glucose control in patients with type 2 diabetes resulted in a lower rate of major vascular events, particularly reducing nephropathy, but did not significantly affect macrovascular events, cardiovascular death, or overall mortality after about 5 years.
  • The study found that while intensive control lowered the average glycated hemoglobin levels (65 vs 73), it was associated with a higher risk of severe hypoglycemia (27 vs 15 cases per 1000 patients).
  • Overall, intensive glucose management offers some benefits in reducing microvascular complications like nephropathy, but it does not strongly impact macrovascular outcomes or survival, and it increases the risk of hypoglycemia.]

Top posts

Most liked on X and Bluesky
Adam Cifu
@adamcifu · X

Basically just bragging about how incredible our @UChiPritzker students are. These are the papers presented in our Critical Appraisal of the Landmark Medical Literature course today. I should be getting CME! https://t.co/YTYYx68y1F https://t.co/KPEnSlNRiH https://t.co/ZeRhgnNUvi

Feb 19, 2021 · 9 likes · 26,014 followers View post →
redGDPS Diabetes
@redGDPS · X

Mitos y leyendas de las #sulfonilureas https://t.co/ZMF3DSrukR #3RSredgdps https://t.co/FSAfGwKaJJ

Apr 5, 2019 · 7 likes · 6 shares · 15,485 followers View post →
Utibe R. Essien, MD MPH
@UREssien · X

As for ADVANCE, the first "Action in Diabetes and Vascular Disease: Preterax and Diamicron Modified Release Controlled Evaluation" out in 2008, randomized diabetic patients to receive intervensive vs. standard control and looking at vascular outcomes. 4/ https://t.co/sMPCTRPBK0

Sep 2, 2019 · 1 like · 23,911 followers View post →
Deirdre Tobias, ScD
@deirdre_tobias · X

@UweJhn1 References: 1/n Glucose control and vascular complications in veterans with type 2 diabetes - PubMed (https://t.co/Bsjhdq80tA) Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes - PubMed (https://t.co/Bsjhdq80tA)

Jul 19, 2024 · 1 like · 9,608 followers View post →
Deirdre Tobias, ScD
@deirdre_tobias · X

@UweJhn1 2/n https://t.co/uFjLI3wWqk https://t.co/J0wvyLfwfy https://t.co/XXk45orwPU https://t.co/g7uMpWmgaH

Jul 19, 2024 · 1 like · 9,608 followers View post →
Nick
@upRootNutrition · X

@kalashnikity @thelowcarb_rd Insulin resistance isn't the target for therapy with therapies that increase serum insulin; blood glucose is. This improves hyperglycemia-related outcomes. https://t.co/TTIG3u26xG

May 9, 2024 · 1 like · 9,478 followers View post →

All mentions

Deirdre Tobias, ScD
@deirdre_tobias · X

@UweJhn1 2/n https://t.co/uFjLI3wWqk https://t.co/J0wvyLfwfy https://t.co/XXk45orwPU https://t.co/g7uMpWmgaH

Jul 19, 2024 · 1 like · 9,608 followers View post →
Deirdre Tobias, ScD
@deirdre_tobias · X

@UweJhn1 References: 1/n Glucose control and vascular complications in veterans with type 2 diabetes - PubMed (https://t.co/Bsjhdq80tA) Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes - PubMed (https://t.co/Bsjhdq80tA)

Jul 19, 2024 · 1 like · 9,608 followers View post →
Nick
@upRootNutrition · X

@kalashnikity @thelowcarb_rd Insulin resistance isn't the target for therapy with therapies that increase serum insulin; blood glucose is. This improves hyperglycemia-related outcomes. https://t.co/TTIG3u26xG

May 9, 2024 · 1 like · 9,478 followers View post →
Dr. StAR
@danielestrell12 · X

RT @redGDPS: Mitos y leyendas de las #sulfonilureas https://t.co/ZMF3DSrukR #3RSredgdps https://t.co/FSAfGwKaJJ

Feb 26, 2024 · 6 shares · 51 followers View post →
SciSpace
@scispace_ · X

Intensive Blood Glucose Control and Vascular Outcomes in Patients with Type2 Diabetes Read more at: https://t.co/nTCP5pd2eL @macmahonstephen @BruceNeal1 @LaurentJBillot @PaulGlasziou @Grobbee @simonrheller @rohinajoshi @Sydney_Uni @IcahnMountSinai @HRIAust @UQ_News @UniofOxford https://t.co/RV1Wojtu15

Sep 28, 2022 · 84,964 followers View post →
SciSpace
@scispace · X

Intensive Blood Glucose Control and Vascular Outcomes in Patients with Type2 Diabetes Read more at: https://t.co/nTCP5pd2eL @macmahonstephen @BruceNeal1 @LaurentJBillot @PaulGlasziou @Grobbee @simonrheller @rohinajoshi @Sydney_Uni @IcahnMountSinai @HRIAust @UQ_News @UniofOxford https://t.co/RV1Wojtu15

Sep 28, 2022 · 84,854 followers View post →
Adam Cifu
@adamcifu · X

Basically just bragging about how incredible our @UChiPritzker students are. These are the papers presented in our Critical Appraisal of the Landmark Medical Literature course today. I should be getting CME! https://t.co/YTYYx68y1F https://t.co/KPEnSlNRiH https://t.co/ZeRhgnNUvi

Feb 19, 2021 · 9 likes · 26,014 followers View post →
Rainer Pliquett
@MeringSymposium · X

Intensive Blood Glucose Control and Vascular Outcomes in Patients with Type 2 Diabetes | NEJM https://t.co/LxfQxTbJqG

May 2, 2020 · 10 followers View post →
Utibe R. Essien, MD MPH
@UREssien · X

As for ADVANCE, the first "Action in Diabetes and Vascular Disease: Preterax and Diamicron Modified Release Controlled Evaluation" out in 2008, randomized diabetic patients to receive intervensive vs. standard control and looking at vascular outcomes. 4/ https://t.co/sMPCTRPBK0

Sep 2, 2019 · 1 like · 23,911 followers View post →
David Arjona
@JDavidArjona · X

RT @redGDPS: Mitos y leyendas de las #sulfonilureas https://t.co/ZMF3DSrukR #3RSredgdps https://t.co/FSAfGwKaJJ

Apr 12, 2019 · 6 shares · 381 followers View post →
Antonieta Vidal
@AntonietaVidalT · X

RT @redGDPS: Mitos y leyendas de las #sulfonilureas https://t.co/ZMF3DSrukR #3RSredgdps https://t.co/FSAfGwKaJJ

Apr 5, 2019 · 6 shares · 1,235 followers View post →
Fco Carramiñana Barrera
@fcbzafra · X

RT @redGDPS: Mitos y leyendas de las #sulfonilureas https://t.co/ZMF3DSrukR #3RSredgdps https://t.co/FSAfGwKaJJ

Apr 5, 2019 · 6 shares · 2,753 followers View post →
redGDPS Diabetes
@redGDPS · X

Mitos y leyendas de las #sulfonilureas https://t.co/ZMF3DSrukR #3RSredgdps https://t.co/FSAfGwKaJJ

Apr 5, 2019 · 7 likes · 6 shares · 15,485 followers View post →
FOAM Cards
@FOAM_Cards · X

(1/2)Trial of the day: ADVANCE Patel A, et al. "Intensive Blood Glucose Control and Vascular Outcomes in Patients with Type 2 Diabetes". The New England Journal of Medicine. 2008. 358(24):2560-2572. https://t.co/ujL2ndwA6d #FOAMcards

Jan 26, 2019 · 68 followers View post →