PubHawk
October 2008 PMID 18815740

Phytoestrogens and breast cancer: a complex story.

W G Helferich, J E Andrade, M S Hoagland

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Mentions

7
Peak: 3 in Jun 2016
across 4 sources since Jun 2016

Extended reach

301,945
potential audience

Total likes

6,760

Video views

301,838

Mentions per month

Jun 2016 – Oct 2025

Where it's discussed

  • Blogs3 articles
  • YouTube2 videos
  • X / Twitter1 posts
  • News1 articles

AI synopsis

What people are saying

The posts express a mild disagreement with the article by highlighting the presence of other carcinogenic compounds in plants and questioning the focus on soy's estrogenic effects, using informal language and humor to convey skepticism and limited engagement.

AgreementLow agreement

The discussion challenges the article's focus by emphasizing other carcinogenic substances in plants and questioning the emphasis on phytoestrogens, reflecting mild disagreement.

InterestNeutral interest

The posts show ambivalence; there's some engagement with the topic but not a deep interest or enthusiasm.

EngagementLow engagement

The tone suggests skepticism and dismissiveness, with comments like 'lol,' indicating superficial engagement rather than detailed analysis.

ImpactLow impact

The discussion doesn’t seem to influence broader opinions or policies, as it mostly revolves around questioning specific points without proposing concrete changes or actions.

Abstract in brief

  • Genistein is an isoflavone found in soy that mimics estrogen and can promote the growth of estrogen-dependent breast tumors, both in laboratory settings and in animals.
  • The way soy products are processed, such as soy protein isolate versus soy flour, influences genistein's effects, with purified forms tending to stimulate tumor growth more significantly than less processed soy.
  • Genistein increases the activity of estrogen target genes like pS2, progesterone receptor, and cyclin D1, which are linked to tumor growth, and its interaction with breast cancer treatments like tamoxifen is also being researched.
Read the full abstract

Top posts

Most liked on X and Bluesky
Dieter Trumpf
@murdoc222 · X

@Bioprinz @ThePrie89 Sie behaupten hier sehr einseitig und unausgewogen. Es gibt eine Vielzahl ein karzinogenen Stoffen in Pflanzen aber Neu5Gc ist natürlich für das hochkomplexe Krankheitsbild Krebs verantwortlich. lol. Allein die östrogene Wirkung von Soja. https://t.co/xBYsCihjo3

Jun 30, 2021 · 68 followers View post →

All mentions

Dieter Trumpf
@murdoc222 · X

@Bioprinz @ThePrie89 Sie behaupten hier sehr einseitig und unausgewogen. Es gibt eine Vielzahl ein karzinogenen Stoffen in Pflanzen aber Neu5Gc ist natürlich für das hochkomplexe Krankheitsbild Krebs verantwortlich. lol. Allein die östrogene Wirkung von Soja. https://t.co/xBYsCihjo3

Jun 30, 2021 · 68 followers View post →
Perspective: Iso Avones Intriguing Molecules But Much Remains To ...
News

reduction in post-menopausal women consuming a novel oral 219–226, https://doi.org/10.1007/s10787-008-8020-0. supplement: a double-blind ...

Oct 21, 2025 View →
Page 49 - New Drug Approvals
Blogs

“Phytoestrogens and breast cancer: A complex story”. Inflammopharmacology 16 (5): 219–26. doi:10.1007/s10787-008-8020-0. PMID 18815740. Jump ...

Jun 14, 2016 View →
Genistein | New Drug Approvals
Blogs

“Phytoestrogens and breast cancer: A complex story”. Inflammopharmacology 16 (5): 219–26. doi:10.1007/s10787-008-8020-0. PMID 18815740. Jump ...

Jun 13, 2016 View →
June | 2016 | New Drug Approvals | Page 7
Blogs

“Phytoestrogens and breast cancer: A complex story”. Inflammopharmacology 16 (5): 219–26. doi:10.1007/s10787-008-8020-0. PMID 18815740. Jump ...

Jun 13, 2016 View →