November 2008 PMID 18951492

Nitric oxide and the paranasal sinuses.

Jon O Lundberg

Mentions

86
Peak: 3 in Apr 2021
across 5 sources since Aug 2020

Extended reach

503,288
potential audience

Total likes

5,596

Video views

463,047

Mentions per month

Aug 2020 – Apr 2025

Where it's discussed

  • News56 articles
  • X / Twitter14 posts
  • Facebook9 posts
  • YouTube4 videos
  • Blogs3 articles

AI synopsis

What people are saying

The selected discussions demonstrate strong interest and engagement, with users referencing scientific studies and practical applications like nasal breathing and humming's effectiveness in increasing nitric oxide. Words like 'fascinates,' 'supports,' and mentions of research articles reflect a tone of curiosity and support for the article's implications, emphasizing its relevance for health practices and diagnostics.

AgreementModerate agreement

Most discussions acknowledge and support the scientific findings about nitric oxide's role in sinus and lung health, with some posts referencing research or clinical implications.

InterestHigh interest

Posts show high interest, with many expressing fascination about the mechanisms and health benefits of nasal nitric oxide, including mentions of breathing practices like humming and Bhramari pranayama.

EngagementHigh engagement

Several contributions delve into specific aspects such as methods (e.g., nasal inhalation, humming) and health impacts, indicating deep engagement and understanding.

ImpactModerate impact

The discussions highlight the potential importance of this research for health practices and disease understanding, though mostly from a supportive or informative stance rather than proposing immediate widespread change.

Abstract in brief

  • The discovery of nitric oxide (NO) production in the paranasal sinuses in 1995 has changed how we understand sinus function, showing that the sinus epithelium constantly produces NO, which helps fight off pathogens and maintain sinus health.
  • NO levels are higher in healthy individuals, but in patients with conditions like primary ciliary dyskinesia (PCD) and cystic fibrosis, NO production is very low, making them more prone to sinus infections and serving as a diagnostic marker for certain diseases like PCD.
  • Additionally, NO from the sinuses is inhaled with each breath, reaching the lungs in a diluted form, where it helps improve oxygen intake by dilating blood vessels, functioning like an "aerocrine hormone" that benefits both sinus and lung health.

Top posts

Most liked on X and Bluesky
Erin K O'Brien MD
@ErinOBrienMD · X

@WardensMD @jacepeabody @formerlypissed @SingleScalpel @HannahRTurb @JBSmithMD @dinkjardine @UAB_OTO @RolvixPatterson @DehraMcGuireMD @JenVillwockMD NO is antimicrobial & may contribute to pulmonary vasodilation when inhaled. It’s an aerocrine molecule and may have additional functions. Nasal NO levels are decreased in chronic sinusitis; exhaled NO can be measured as a marker of disease https://t.co/xxVtZkpQUo

Oct 15, 2020 · 4 likes · 2,922 followers View post →
Karl Etzel
@KarlEtzel · X

@FitFounder Another reason nose breathing is a good thing - nitric oxide production in the paranasal sinuses. https://t.co/TRBi038vs6

Sep 30, 2023 · 3 likes · 655 followers View post →
Gus Power
@guspower · X

Here's a link https://t.co/lZItgJ28kW

Apr 6, 2023 · 1 like · 1,112 followers View post →
Karl Etzel
@KarlEtzel · X

Nose breathing and nitric oxide. This stuff fascinates me. https://t.co/TRBi038vs6

Aug 27, 2023 · 1 like · 655 followers View post →
TruthInScience
@Truth_Scientist · X

As part of your host defense systems, Your sinuses produce Nitric Oxide, a pluripotent gaseous messenger with potent vasodilating, and antimicrobial activity (kills bacteria & viruses) This supports the health benefits of breathe-work & nasal breathing https://t.co/INUS817Svc

Oct 18, 2020 · 1 like · 212 followers View post →
Språkpolisen
@soya_hund · X

@JacobGudiol Munandare har inte syrebrist! MEN näsandning ger lungorna NO. ”NO gas from the nose and sinuses is inhaled with every breath and reaches the lungs in a more diluted form to enhance pulmonary oxygen uptake via local vasodilation.” https://t.co/MlVrv1ItqU

Dec 13, 2023 · 1 like · 89 followers View post →

All mentions

Gargi #Decolonization
@gargiuvacha · X

@UnabashedIndian Since you are interested: Paper Name Link Nitric Oxide and the Paranasal Sinuses https://t.co/IYQqeMo8Pq Humming (Simple Bhramari Pranayama) as a Stress Buster https://t.co/W7j0xA6JMD Humming Greatly Increases Nasal Nitric Oxide https://t.co/wSGmxQS4DU Efficacy

Mar 1, 2025 · 29,546 followers View post →
Språkpolisen
@soya_hund · X

@JacobGudiol Munandare har inte syrebrist! MEN näsandning ger lungorna NO. ”NO gas from the nose and sinuses is inhaled with every breath and reaches the lungs in a more diluted form to enhance pulmonary oxygen uptake via local vasodilation.” https://t.co/MlVrv1ItqU

Dec 13, 2023 · 1 like · 89 followers View post →
No Know Universe, Lot-num.ber si.x.t.nine
@Franky53659510 · X

https://t.co/0kYfbsJQcv

Oct 7, 2023 · 1,060 followers View post →
Karl Etzel
@KarlEtzel · X

@FitFounder Another reason nose breathing is a good thing - nitric oxide production in the paranasal sinuses. https://t.co/TRBi038vs6

Sep 30, 2023 · 3 likes · 655 followers View post →
Karl Etzel
@KarlEtzel · X

Nose breathing and nitric oxide. This stuff fascinates me. https://t.co/TRBi038vs6

Aug 27, 2023 · 1 like · 655 followers View post →
Gus Power
@guspower · X

Here's a link https://t.co/lZItgJ28kW

Apr 6, 2023 · 1 like · 1,112 followers View post →
Gerard Hough
@GerardHough · X

https://t.co/43m2bz5wkG Nitric oxide and the paranasal sinuses

Jan 29, 2023 · 1,757 followers View post →
Petri Pellinen
@petri_pellinen · X

RT @kassula14: " Interestingly... more NO is released from the nasal passages during nasal inhalation compared with exhalation (Tornberg et…

Apr 13, 2022 · 1 share · 1,434 followers View post →
New Earth
@JesusLov3sU222 · X

https://t.co/CkI2rxyZ6P

Aug 28, 2021 · 376 followers View post →
Kaspar Laifour
@kassula14 · X

" Interestingly... more NO is released from the nasal passages during nasal inhalation compared with exhalation (Tornberg et al., 2002). " #NitricOxide and the #Paranasal #Sinuses Jon O. Lundberg 2008 Full text: https://t.co/eQwJYFOpIh #typpioksidi #poskiontelo #aerocrine

Aug 8, 2021 · 1 like · 1 share · 18 followers View post →
Vivek Kamat
@vivkamat · X

1 https://t.co/mVK00RvtyA posted a video about 'Bhramari' being effective in compating nasal in fections by Nitric Oxide secretion in the tract. I just looked up the net and found American Journal of Respiratory and Critical Care Medicine did a reserch

Apr 17, 2021 · 122 followers View post →
TruthInScience
@Truth_Scientist · X

As part of your host defense systems, Your sinuses produce Nitric Oxide, a pluripotent gaseous messenger with potent vasodilating, and antimicrobial activity (kills bacteria & viruses) This supports the health benefits of breathe-work & nasal breathing https://t.co/INUS817Svc

Oct 18, 2020 · 1 like · 212 followers View post →
Erin K O'Brien MD
@ErinOBrienMD · X

@WardensMD @jacepeabody @formerlypissed @SingleScalpel @HannahRTurb @JBSmithMD @dinkjardine @UAB_OTO @RolvixPatterson @DehraMcGuireMD @JenVillwockMD NO is antimicrobial & may contribute to pulmonary vasodilation when inhaled. It’s an aerocrine molecule and may have additional functions. Nasal NO levels are decreased in chronic sinusitis; exhaled NO can be measured as a marker of disease https://t.co/xxVtZkpQUo

Oct 15, 2020 · 4 likes · 2,922 followers View post →
not-a-real-doctor strange
@dankloke · X

Production of NO occurs in paranasal sinuses. https://t.co/8NwlG25XJ8 "The NO concentration in a healthy sinus exceeds those that are needed for antibacterial effects in vitro." https://t.co/2WjXWYxSiA Humming Greatly Increases Nasal Nitric Oxide https://t.co/dRcB9dncU8 https://t.co/FjoGSLn3UY

Aug 23, 2020 · 280 followers View post →