Hypertens Res August 2008 PMID 18971533

Effects of nattokinase on blood pressure: a randomized, controlled trial.

Ji Young Kim, Si Nae Gum, Jean Kyung Paik, Hyo Hee Lim, Kyong-Chol Kim, Kazuya Ogasawara, Kenichi Inoue, Sungha Park, Yangsoo Jang, Jong Ho Lee

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Mentions

Peak: 4 in Aug 2025

across 5 sources since Jan 2021

Extended reach

418,519

potential audience

Total likes

7,979

Video views

285,110

Mentions per month

Jan 2021 – Aug 2025

Where it's discussed

X / Twitter25 posts
News6 articles
Facebook5 posts
Blogs3 articles
YouTube2 videos

AI synopsis

What people are saying

The group shows strong interest with posts mentioning research results and personal anecdotes, such as one user noting that nattokinase helped their cat with a heart condition. The tone varies from cautious acknowledgment to enthusiasm about its potential, with some users questioning biases or emphasizing the need for further research to determine its true impact.

AgreementModerate agreement

Most comments recognize the positive findings of the study and support the potential benefits of nattokinase for blood pressure regulation.

InterestHigh interest

Discussions show high curiosity about nattokinase, with many posts referencing research, personal use, and asking questions about its effects.

EngagementModerate engagement

Posts demonstrate moderate engagement through sharing personal experiences, questioning, and referencing scientific concepts like enzyme activity and trial results.

ImpactModerate impact

The collective tone suggests that the publication could influence how people view nattokinase as a supplement for blood pressure management, though it's not seen as conclusive yet.

Abstract in brief

The study investigated how nattokinase, a supplement, affects blood pressure in people with prehypertension or stage 1 hypertension and found that it significantly lowered both systolic and diastolic blood pressure after 8 weeks.
Participants taking nattokinase also showed a decrease in renin activity, an enzyme involved in blood pressure regulation, indicating a potential mechanism for its blood pressure-lowering effects.
Overall, the results suggest that nattokinase could be useful for preventing and treating hypertension, but further research is needed to confirm these findings.]

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All mentions

Nattokinase's Impact on Blood Pressure and Cardiovascular Risk

The study found that consuming nattokinase, a fermented soy extract, can reduce blood pressure in hypertensive individuals, especially in males, and decrease cardiovascular risk markers like von Willebrand factor…

Physionic · Jun 10, 2024 249,929 views

Nattokinase and Heart Health: Effectiveness in Atherosclerosis Prevention

This study tested whether nattokinase, a supplement thought to benefit heart health, actually slows down the development of early atherosclerosis and improves related blood markers. Over about 3 years, participants…

Physionic · May 3, 2024 31,013 views

Understanding Vitamin K Intake Limits for Warfarin Patients

This review examines safe vitamin K intake levels for warfarin users, indicating a tolerable range of 25 to 325 micrograms daily, with about 150 micrograms optimal. Avoiding high vitamin K foods like natto is advised to…

【下川先生】の菌ケア大学 · Mar 15, 2024 4,169 views

klamka

@pustaera · X

RT @BowTiedVitamins: https://t.co/opC7PY2ReP

Aug 23, 2025 · 2 shares · 514 followers View post →

cs hernandez

@cshernandez123 · X

RT @BowTiedVitamins: https://t.co/opC7PY2ReP

Aug 21, 2025 · 2 shares · 490 followers View post →

Vitamin King | Stacks Vitamin Company

@KingOfVitamins · X

https://t.co/opC7PY2ReP

Aug 21, 2025 · 3 likes · 2 shares · 48,020 followers View post →

~Journey P.Ⓥ︎

@SouLJOo0oOurney · X

Nattokinase: Plaque Reversing Supplement, or Biased Science? https://t.co/z4j8C18xo8 via @YouTube

Aug 2, 2025 · 1,447 followers View post →

BlackSandSurf Costa Rica

@blacksandsurf · X

RT @LivingAlpha1: Video credits: YT link: https://t.co/ispYtgeivT YT link: https://t.co/gOV3IS8nLM YT link: https://t.co/XyyjDhmF5w YT link…

Feb 5, 2025 · 3 shares · 42 followers View post →

Donald_Pureblood

@DonaldShimoda4 · X

RT @LivingAlpha1: Video credits: YT link: https://t.co/ispYtgeivT YT link: https://t.co/gOV3IS8nLM YT link: https://t.co/XyyjDhmF5w YT link…

Feb 5, 2025 · 3 shares · 503 followers View post →

Kulbir Sohi

@LivingAlpha1 · X

Feb 5, 2025 · 22 likes · 3 shares · 3,943 followers View post →

Metal 私己メタル 메탈

@Metal_Terium · X

Nattokinase: Plaque Reversing Supplement, or Biased Science? - YouTube https://t.co/LO4BkIgFJ9

Jan 31, 2025 · 481 followers View post →

Antoine Decurtis

@decurtis22 · X

@JacquiDeevoy1 https://t.co/4d6ZgP8fNx. Of course, This is not a medical advice.

Jan 29, 2025 · 46 followers View post →

RastyCat

@rasty_cat · X

@catturd2 Ask yer doc(s) about nattokinase. Japanese eat nasty tasting old femented soybeans dish called “Natto”, however there are supplements available. Japanese have good bp from what I understand. Just started takin myself. Good luck ! https://t.co/IiQJchKNVx

Jan 24, 2025 · 88 followers View post →

Alex Gorman

@AlexGorman777 · X

@biohacker https://t.co/cqQXBFaztu

Nov 18, 2024 · 31 followers View post →

DeEtta Famiano

@TheRealFamiano · X

@Cowboyw2b2 Nattokinase worked for me. https://t.co/xRObpjSkCK

Aug 18, 2024 · 10 followers View post →

A&Z MD

@AZMD_1 · X

@LTHABIB @RealDrJaneRuby Also decreases BP in double blind placebo RCT. I wouldn’t call it “snake oil”. https://t.co/YVMtBqNrtu

Jan 31, 2024 · 9,362 followers View post →

JJ. Rapid - My pronouns - Silver/Tip

@JJCrosstrainers · X

Jan 15, 2024 · 3 likes · 2,953 followers View post →

Math3145

@Math3145 · X

@tatiann69922625 @Annette_LEXA @CorinneReverbel @marseille_jeff @alainhoupert @AnneliseBocquet https://t.co/IZdFm7Tk15 https://t.co/GVXvNVR9uX

Jan 13, 2024 · 3,127 followers View post →

❤

@19961995sw · X

RT @BowTiedVitamins: https://t.co/opC7PY2ReP

Dec 4, 2023 · 1 share · 2,931 followers View post →

Vitamin King | Stacks Vitamin Company

@KingOfVitamins · X

https://t.co/opC7PY2ReP

Dec 4, 2023 · 6 likes · 1 share · 48,020 followers View post →

indigonaturals

@NaturalsIndigo · X

check out the research on nattokinase and BP after 8 weeks? Interesting and the anti-clotting is a bonus in today's world. https://t.co/k9eO3xvlja https://t.co/k7wtgNPyNp

Sep 25, 2023 · 1 like · 494 followers View post →

EnRigtigLøveMor

@mrsNoGenJuice · X

@JustOwnItIsrael @DrSyedHaider If a person has low blood pressure, is nattokinase still to recommand…As I read it - nattokinase lower bloodpresure…?? https://t.co/y2j9WVWpwk

Aug 31, 2023 · 2,624 followers View post →

Perspect

@Perspec01314687 · X

@RemnantMd I'd like to get your thoughts on this RCT https://t.co/b9UxUkGJvW

May 16, 2023 · 1 like · 159 followers View post →

JeffWill

@J_Real3 · X

https://t.co/3HnPou2AAa

Mar 25, 2023 · 5,053 followers View post →

Earthling

@_earthling74 · X

@lipo_fan https://t.co/6a2ofCAvky

Mar 3, 2023 · 1 like · 428 followers View post →

Whippet servant

@aye_lass · X

@em_loo_g Nattokinase supplement. https://t.co/W5PPncSSuX

May 19, 2022 · 1,105 followers View post →

@Yutablog1 · X

納豆に含まれるナットウキナーゼは高血圧を予防する効果があります。納豆には他にも気になる栄養素が含まれてるから調べてて楽しい

Mar 2, 2021 · 12 likes · 1,276 followers View post →

fluidx

@KnottygirlVP · X

@Khanoisseur Nattokinase. Good for the heart, stops blood clots, lowers blood pressure. My cat has advanced heart issue, should have passed 2 yrs ago but instead is healthy and active tks to Nattokinase. https://t.co/maycTPNBwV

Jan 15, 2021 · 230 followers View post →

Effects of nattokinase on blood pressure: a randomized, controlled trial.

Mentions per month

Where it's discussed

What people are saying

Abstract in brief

Top posts

All mentions

Nattokinase's Impact on Blood Pressure and Cardiovascular Risk

Nattokinase and Heart Health: Effectiveness in Atherosclerosis Prevention

Understanding Vitamin K Intake Limits for Warfarin Patients