N Engl J Med October 1991 PMID 1922210

Licorice-induced hypermineralocorticoidism.

R V Farese, E G Biglieri, C H Shackleton, I Irony, R Gomez-Fontes

Mentions

29
Peak: 10 in May 2019
across 4 sources since Mar 2019

Extended reach

5,567,446
potential audience

Total likes

97,540

Video views

5,289,257

Mentions per month

Mar 2019 – Mar 2023

Where it's discussed

  • X / Twitter22 posts
  • YouTube3 videos
  • Bluesky2 posts
  • Facebook2 posts

AI synopsis

What people are saying

Overall, discussions show a strong interest in understanding licorice's effects, with posts describing real-world scenarios like kidney issues from excessive tea consumption and emphasizing the importance of careful supplement inquiry. The tone combines technical details with practical advice, reflecting deep engagement and recognition of the article's clinical relevance.

AgreementModerate agreement

Most discussions acknowledge the relevance of licorice's effects on mineralocorticoid activity, with some suggesting clarifications on hormone interactions.

InterestHigh interest

The topic sparks high curiosity, evidenced by posts highlighting clinical implications, safety concerns, and the biochemical mechanisms involved.

EngagementModerate engagement

Participants reference specific treatments like amiloride, mention case studies, and debate terminologies, indicating active engagement.

ImpactModerate impact

The discussions highlight practical concerns about supplement use and medical diagnosis, suggesting moderate influence on clinical awareness and public health.

Abstract in brief

  • The text discusses a condition called licorice-induced hypermineralocorticoidism, which occurs when consuming licorice leads to excessive activity of mineralocorticoid hormones.
  • It explains how certain compounds in licorice, like glycyrrhizin, can interfere with the body's aldosterone regulation, causing symptoms like high blood pressure, low potassium levels, and fluid retention.
  • The article likely covers the clinical implications, diagnosis, and possible treatment options for this condition caused by licorice consumption.]

Top posts

Most liked on X and Bluesky
Nayan Arora,MD
@captainchloride · X

She was started on amiloride which helped maintain normal potassium levels until the licorice wore off - ~10 days Illustrates how important it is to ask about all supplements, herbs, etc. Read about licorice induced hypermineralocorticoidism here: https://t.co/mArxwpkfq5

Jun 17, 2022 · 56 likes · 4 shares · 3,404 followers View post →
Fadel Alrowaie
@fadelrowaie · X

الاكثار من تناول عرق السوس كعصير او كحلويات تباع بالمجمعات التجارية يتناولها الاطفال قد يسبب ارتفاع في ضغط الدم و انخفاض شديد في البوتاسيوم بالجسم #اليوم_العالمي_لارتفاع_ضغط_الدم Licorice-Induced Hypermineralocorticoidism | NEJM https://t.co/9g9JJ7L92P https://t.co/Jg9ET52gw9

May 18, 2019 · 22 likes · 11 shares · 25,018 followers View post →
Dr. Seham Socchia - د. سهام
@Seham_Ita · X

العرق سوس .. كعصير او حلويات الاكثار منه '' يساهم في ارتفاع ضغط الدم .. ويسبب انخفاض ملحوظ في البوتاسيوم .. .. https://t.co/wUmvhsN75N… . https://t.co/fNmYVfqjXR

Aug 28, 2020 · 7 likes · 61,840 followers View post →
Mark Lewis, MD, FASCO
@marklewismd · X

An instructive case is also described here (since the New England Journal is SO hot right now); deglycyrrhizinated licorice remains in non-prescription use as a remedy for dyspepsia and some ulcers: https://t.co/PDHeeON7TV

Oct 11, 2022 · 3 likes · 92,912 followers View post →
J. Brian Byrd Lab
@thebyrdlab · X

@DrJMLuther @brzoskos I like it--but it should say hypermineralocorticoid + _hypo_aldosteronism if licorice is at issue! https://t.co/5LT3YnGC9J https://t.co/Flw67v2dec

Mar 26, 2019 · 3 likes · 1 share · 4,600 followers View post →
BeanQueen Gaddy
@AnnaGaddy · X

@AlexanderDent6 https://t.co/4IM56Z6Jwc

Apr 12, 2021 · 3 likes · 3,734 followers View post →

All mentions

wholistic
@wholisticguy · X

@jimtalbot @trader1sz Careful you don’t overdo the Liquorice tea, I was having it every day for a while and I think it fucked up my kidneys a bit https://t.co/br5xAzOVX8

Mar 12, 2023 · 7,446 followers View post →
Mark Lewis, MD, FASCO
@marklewismd · X

An instructive case is also described here (since the New England Journal is SO hot right now); deglycyrrhizinated licorice remains in non-prescription use as a remedy for dyspepsia and some ulcers: https://t.co/PDHeeON7TV

Oct 11, 2022 · 3 likes · 92,912 followers View post →
MrinalMkrishna
@MrinalMkrishna · X

@DrCindyCooper https://t.co/RdhWDTuxjL

Oct 6, 2022 · 53 followers View post →
Ashish Sharma
@AKS_KidneyDoc · X

RT @captainchloride: She was started on amiloride which helped maintain normal potassium levels until the licorice wore off - ~10 days Il…

Jun 18, 2022 · 4 shares · 184 followers View post →
Nayan Arora
@captainchloride.bsky.social · Bluesky

https://pubmed.ncbi.nlm.nih.gov/1922210/

Jun 17, 2022 View post →
Nayan Arora
@captainchloride.bsky.social · Bluesky

She was started on amiloride which helped maintain normal potassium levels until the licorice wore off - ~10 days Illustrates how important it is to ask about all supplements, herbs, etc. Read about licorice induced hypermineralocorticoidism here:...

Jun 17, 2022 · 1 share View post →
Nayan Arora,MD
@captainchloride · X

She was started on amiloride which helped maintain normal potassium levels until the licorice wore off - ~10 days Illustrates how important it is to ask about all supplements, herbs, etc. Read about licorice induced hypermineralocorticoidism here: https://t.co/mArxwpkfq5

Jun 17, 2022 · 56 likes · 4 shares · 3,404 followers View post →
Kenar Jhaveri
@kdjhaveri · X

@mankadmd but if you take it for years, the prolonged suppression of 11β-hydroxysteroid dehydrogenase activity appears to a problem: -the unstimulated renin-aldosterone system can be suppressed for nearly months after the cessation of licorice ingestion. https://t.co/H8SobpbzXr.

Feb 1, 2022 · 1 like · 11,650 followers View post →
Fadel Alrowaie
@fadelrowaie · X

RT @fadelrowaie: الاكثار من تناول عرق السوس كعصير او كحلويات تباع بالمجمعات التجارية يتناولها الاطفال قد يسبب ارتفاع في ضغط الدم و انخفاض…

Apr 13, 2021 · 11 shares · 25,018 followers View post →
BeanQueen Gaddy
@AnnaGaddy · X

@AlexanderDent6 https://t.co/4IM56Z6Jwc

Apr 12, 2021 · 3 likes · 3,734 followers View post →
Maximilien Rappaport, DO
@MaxRappaportDO · X

Glycyrrhizic acid from black licorice inhibits 11-beta-HSD2 leading to a syndrome of apparent mineralocorticoid excess! https://t.co/lNLriSljHn https://t.co/o85QmIzhNq https://t.co/Ca4EddgnQc

Oct 24, 2020 · 518 followers View post →
Dr. Seham Socchia - د. سهام
@Seham_Ita · X

العرق سوس .. كعصير او حلويات الاكثار منه '' يساهم في ارتفاع ضغط الدم .. ويسبب انخفاض ملحوظ في البوتاسيوم .. .. https://t.co/wUmvhsN75N… . https://t.co/fNmYVfqjXR

Aug 28, 2020 · 7 likes · 61,840 followers View post →
سعد السبيت | #صديق_الكلى
@kidney_friend · X

RT @fadelrowaie: الاكثار من تناول عرق السوس كعصير او كحلويات تباع بالمجمعات التجارية يتناولها الاطفال قد يسبب ارتفاع في ضغط الدم و انخفاض…

May 22, 2019 · 11 shares · 1,340 followers View post →
احمد جلال منصور سيف الحمادي
@fd4y7 · X

RT @fadelrowaie: الاكثار من تناول عرق السوس كعصير او كحلويات تباع بالمجمعات التجارية يتناولها الاطفال قد يسبب ارتفاع في ضغط الدم و انخفاض…

May 18, 2019 · 11 shares · 590 followers View post →
محمد الراشد
@alrashed777 · X

RT @fadelrowaie: الاكثار من تناول عرق السوس كعصير او كحلويات تباع بالمجمعات التجارية يتناولها الاطفال قد يسبب ارتفاع في ضغط الدم و انخفاض…

May 18, 2019 · 11 shares · 1,757 followers View post →
A s m a Malwi
@PhsmSam · X

RT @fadelrowaie: الاكثار من تناول عرق السوس كعصير او كحلويات تباع بالمجمعات التجارية يتناولها الاطفال قد يسبب ارتفاع في ضغط الدم و انخفاض…

May 18, 2019 · 11 shares · 1,002 followers View post →
Mohammed Mar'ae Asiri
@Asiritrauma1 · X

RT @fadelrowaie: الاكثار من تناول عرق السوس كعصير او كحلويات تباع بالمجمعات التجارية يتناولها الاطفال قد يسبب ارتفاع في ضغط الدم و انخفاض…

May 18, 2019 · 11 shares · 18,220 followers View post →
Hanaa S. Noor
@noor_hanaa · X

RT @fadelrowaie: الاكثار من تناول عرق السوس كعصير او كحلويات تباع بالمجمعات التجارية يتناولها الاطفال قد يسبب ارتفاع في ضغط الدم و انخفاض…

May 18, 2019 · 11 shares · 259 followers View post →
أسعد حجازي
@as3adhijazi · X

RT @fadelrowaie: الاكثار من تناول عرق السوس كعصير او كحلويات تباع بالمجمعات التجارية يتناولها الاطفال قد يسبب ارتفاع في ضغط الدم و انخفاض…

May 18, 2019 · 11 shares · 459 followers View post →
not me
@Aljazita · X

RT @fadelrowaie: الاكثار من تناول عرق السوس كعصير او كحلويات تباع بالمجمعات التجارية يتناولها الاطفال قد يسبب ارتفاع في ضغط الدم و انخفاض…

May 18, 2019 · 11 shares · 15,937 followers View post →
حتى إشعار آخر.
@HfcX2oDVmTCIDfh · X

RT @fadelrowaie: الاكثار من تناول عرق السوس كعصير او كحلويات تباع بالمجمعات التجارية يتناولها الاطفال قد يسبب ارتفاع في ضغط الدم و انخفاض…

May 18, 2019 · 11 shares · 48 followers View post →
Fadel Alrowaie
@fadelrowaie · X

الاكثار من تناول عرق السوس كعصير او كحلويات تباع بالمجمعات التجارية يتناولها الاطفال قد يسبب ارتفاع في ضغط الدم و انخفاض شديد في البوتاسيوم بالجسم #اليوم_العالمي_لارتفاع_ضغط_الدم Licorice-Induced Hypermineralocorticoidism | NEJM https://t.co/9g9JJ7L92P https://t.co/Jg9ET52gw9

May 18, 2019 · 22 likes · 11 shares · 25,018 followers View post →
Szymon Brzósko
@brzoskos · X

RT @thebyrdlab: @DrJMLuther @brzoskos I like it--but it should say hypermineralocorticoid + _hypo_aldosteronism if licorice is at issue! h…

Mar 26, 2019 · 1 share · 1,937 followers View post →
J. Brian Byrd Lab
@thebyrdlab · X

@DrJMLuther @brzoskos I like it--but it should say hypermineralocorticoid + _hypo_aldosteronism if licorice is at issue! https://t.co/5LT3YnGC9J https://t.co/Flw67v2dec

Mar 26, 2019 · 3 likes · 1 share · 4,600 followers View post →