N Engl J Med March 2009 PMID 19297565

Mortality results from a randomized prostate-cancer screening trial.

Gerald L Andriole, E David Crawford, Robert L Grubb, Saundra S Buys, David Chia, Timothy R Church, Mona N Fouad, Edward P Gelmann, Paul A Kvale, Douglas J Reding, Joel L Weissfeld, Lance A Yokochi, Barbara O'Brien, Jonathan D Clapp, Joshua M Rathmell

Download social card

Mentions

61
Peak: 4 in Sep 2025
across 5 sources since Aug 2020

Extended reach

17,069
potential audience

Total likes

191

Video views

3,543

Mentions per month

Aug 2020 – Sep 2025

Where it's discussed

  • Blogs23 articles
  • News22 articles
  • X / Twitter8 posts
  • YouTube6 videos
  • Facebook2 posts

AI synopsis

What people are saying

The discussions reflect mixed opinions, with some posters emphasizing that the study confirms prior doubts about the effectiveness of screening, using words like 'yet to be proven' and 'doesn't work,' which indicates skepticism. Others highlight regional differences, such as the impact on Malaysia's screening policies, showing how the publication influences policy debates and perceptions of screening's value, though without deeply engaging in methodological critiques.

AgreementNeither agree nor disagree

Most discussions express skepticism or neutrality regarding the findings, with some agreeing with the idea that screening doesn't significantly reduce mortality, while others challenge or question the conclusions.

InterestModerate interest

The discussions show mild curiosity, mainly focusing on the implications of the study rather than deep analysis, indicating moderate interest.

EngagementNeutral engagement

Posts appear to mainly acknowledge the findings without extensive debate or detailed commentary, reflecting neutral or passive engagement.

ImpactModerate impact

The conversations suggest that the article influences opinions about prostate cancer screening policies, especially in contexts like Malaysia, where practices differ, hinting at some impact on clinical decisions or public health considerations.

Abstract in brief

  • The study examined whether prostate cancer screening using PSA tests and digital rectal exams reduces death rates.
  • Over about 7 to 10 years, slightly more prostate cancers were diagnosed in the screened group, but death rates from prostate cancer were similar between those who were screened and those who weren’t.
  • The findings suggest that, within this timeframe, prostate cancer screening did not significantly lower mortality rates, though it increased the diagnosis of prostate cancer.]

Top posts

Most liked on X and Bluesky
Wei Shen Tan
@drtanws · X

@Kenrickng1 @ProfAdeeba @nazrazak @teng_ong @EChrisDee However in #malaysia where PSA screening is not common, promoting PSA screening will save lives. The arguments based on the PLCO trail against PSA screening is not valid in a country with poor PSA screening penetration like Msia unlike the USA https://t.co/4lNf3NKJcM

Oct 31, 2020 · 4 likes · 1,274 followers View post →
Jeremy Sussman
@JeremySussman · X

@djc795 @instrumenthull @metrics52 And in a time of low-cost nudge-y effectiveness trials being used for causal inference (and hence shrinking intervention adherence) that benefit is becoming ever more important, but it's still quite secondary. Example paper - https://t.co/labQZMPG2D

Jul 11, 2023 · 2 likes · 1,944 followers View post →
Dr MJ, Mr Boh
@DrMJMrBoh · X

@LyndaJane8 @RichelTheo @quay_dr https://t.co/SkFnzB2t9t https://t.co/fjWvPIQJsX https://t.co/dPciYm1vte https://t.co/GkkKl8suQf.

May 19, 2025 · 1 like · 598 followers View post →
timrchurch
@timrchurch · X

@_YoungCR7 Prostate screening doesn't work. https://t.co/EtVqj8FdtU

Aug 29, 2020 · 5,829 followers View post →
次郎作
@zilousaku · X

授業では、PLCOの論文の方だけcontaminationが52%と強調されてたのは、さすがにちょっと議論を誘導したんだろうなぁと思いました笑 https://t.co/BgnOBs4QaE

Jun 22, 2021 · 2,729 followers View post →
Mr Anonymous
@WLancsGP · X

@SimonMDLord @oscdebosc @ProstateUK Yet to be proven https://t.co/GrltR6orEy

Jun 17, 2023 · 906 followers View post →

All mentions

Dr MJ, Mr Boh
@DrMJMrBoh · X

@LyndaJane8 @RichelTheo @quay_dr https://t.co/SkFnzB2t9t https://t.co/fjWvPIQJsX https://t.co/dPciYm1vte https://t.co/GkkKl8suQf.

May 19, 2025 · 1 like · 598 followers View post →
Msc Rodrigo Volga
@RodrigoVolga · X

@lualopes_12 @Minguebson @timao_chico @luizpaulor https://t.co/QDMXCDO0h9

Nov 6, 2023 · 127 followers View post →
Jeremy Sussman
@JeremySussman · X

@djc795 @instrumenthull @metrics52 And in a time of low-cost nudge-y effectiveness trials being used for causal inference (and hence shrinking intervention adherence) that benefit is becoming ever more important, but it's still quite secondary. Example paper - https://t.co/labQZMPG2D

Jul 11, 2023 · 2 likes · 1,944 followers View post →
Mr Anonymous
@WLancsGP · X

@SimonMDLord @oscdebosc @ProstateUK Yet to be proven https://t.co/GrltR6orEy

Jun 17, 2023 · 906 followers View post →
Rad Onc Commentary
@radoncpub · X

Comorbidity and mortality results from a randomized prostate cancer screening trial https://t.co/YzpNIUYHO6

Jul 2, 2021 · 120 followers View post →
次郎作
@zilousaku · X

授業では、PLCOの論文の方だけcontaminationが52%と強調されてたのは、さすがにちょっと議論を誘導したんだろうなぁと思いました笑 https://t.co/BgnOBs4QaE

Jun 22, 2021 · 2,729 followers View post →
Wei Shen Tan
@drtanws · X

@Kenrickng1 @ProfAdeeba @nazrazak @teng_ong @EChrisDee However in #malaysia where PSA screening is not common, promoting PSA screening will save lives. The arguments based on the PLCO trail against PSA screening is not valid in a country with poor PSA screening penetration like Msia unlike the USA https://t.co/4lNf3NKJcM

Oct 31, 2020 · 4 likes · 1,274 followers View post →
timrchurch
@timrchurch · X

@_YoungCR7 Prostate screening doesn't work. https://t.co/EtVqj8FdtU

Aug 29, 2020 · 5,829 followers View post →