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Pain Med November 2009 PMID 19453963

Fibromyalgia symptoms are reduced by low-dose naltrexone: a pilot study.

Jarred Younger, Sean Mackey

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Mentions

17
Peak: 6 in Mar 2021
across 4 sources since Jan 2015

Extended reach

63,379
potential audience

Total likes

60

Video views

1,059

Mentions per month

Jan 2015 – Dec 2025

Where it's discussed

  • X / Twitter7 posts
  • News6 articles
  • YouTube2 videos
  • Facebook2 posts

AI synopsis

What people are saying

Discussions emphasize the potential benefits of low-dose naltrexone, with posts highlighting the original studies and referring to it as a novel, safe, and inexpensive treatment. The tone is supportive and curious, indicating interest in new research and promising therapies.

AgreementModerate agreement

Most posts express support or positive recognition of the study, highlighting the potential benefits of low-dose naltrexone for fibromyalgia.

InterestHigh interest

Posts show high curiosity and enthusiasm, especially with phrases like 'new post' and mentioning the study as 'safe, effective and cheap,' indicating strong engagement.

EngagementModerate engagement

The discussions touch on the research details and potential benefits, such as referencing original studies and mentioning the promotion of the treatment, reflecting thoughtful engagement.

ImpactModerate impact

While the posts promote awareness, the overall tone suggests moderate influence, mainly informing interested individuals rather than changing large public perceptions.

Abstract in brief

  • A pilot study found that low-dose naltrexone significantly reduced fibromyalgia symptoms, with participants experiencing over 30% improvement compared to placebo, and also improved pain sensitivity.
  • The medication works by blocking certain receptors and inhibiting microglia activity in the central nervous system, which may help reverse inflammation related to fibromyalgia.
  • Side effects were minor and short-lived, and individuals with higher inflammation levels (as indicated by erythrocyte sedimentation rate) responded better to the treatment.]
Read the full abstract

Top posts

Most liked on X and Bluesky
Dr. Sean Mackey
@DrSeanMackey · X

I mentioned a novel treatment we studied for fibromyalgia called low dose naltrexone (LDN). These are the original studies we did on this safe, effective and cheap drug. https://t.co/5vqaRZJ1B4 & https://t.co/OL8VzCNzny

Mar 13, 2021 · 16 likes · 5 shares · 8,182 followers View post →
Chris✞chronicpainDAD
@ChronicPainDad · X

RT @DrSeanMackey: I mentioned a novel treatment we studied for fibromyalgia called low dose naltrexone (LDN). These are the original studie…

Mar 19, 2021 · 5 shares · 22,550 followers View post →
Robert West, PhD ✝️
@westr · X

RT @DrSeanMackey: I mentioned a novel treatment we studied for fibromyalgia called low dose naltrexone (LDN). These are the original studie…

Mar 15, 2021 · 5 shares · 19,224 followers View post →
For Grace: Women In Pain
@forgrace · X

RT @DrSeanMackey: I mentioned a novel treatment we studied for fibromyalgia called low dose naltrexone (LDN). These are the original studie…

Mar 14, 2021 · 5 shares · 9,872 followers View post →
Cynthia Toussaint
@BattleforGrace · X

RT @DrSeanMackey: I mentioned a novel treatment we studied for fibromyalgia called low dose naltrexone (LDN). These are the original studie…

Mar 16, 2021 · 5 shares · 1,912 followers View post →
Heather Poupore-King, PhD
@DrHeatherKing · X

RT @DrSeanMackey: I mentioned a novel treatment we studied for fibromyalgia called low dose naltrexone (LDN). These are the original studie…

Mar 14, 2021 · 5 shares · 419 followers View post →

All mentions

Chris✞chronicpainDAD
@ChronicPainDad · X

RT @DrSeanMackey: I mentioned a novel treatment we studied for fibromyalgia called low dose naltrexone (LDN). These are the original studie…

Mar 19, 2021 · 5 shares · 22,550 followers View post →
Cynthia Toussaint
@BattleforGrace · X

RT @DrSeanMackey: I mentioned a novel treatment we studied for fibromyalgia called low dose naltrexone (LDN). These are the original studie…

Mar 16, 2021 · 5 shares · 1,912 followers View post →
Robert West, PhD ✝️
@westr · X

RT @DrSeanMackey: I mentioned a novel treatment we studied for fibromyalgia called low dose naltrexone (LDN). These are the original studie…

Mar 15, 2021 · 5 shares · 19,224 followers View post →
For Grace: Women In Pain
@forgrace · X

RT @DrSeanMackey: I mentioned a novel treatment we studied for fibromyalgia called low dose naltrexone (LDN). These are the original studie…

Mar 14, 2021 · 5 shares · 9,872 followers View post →
Heather Poupore-King, PhD
@DrHeatherKing · X

RT @DrSeanMackey: I mentioned a novel treatment we studied for fibromyalgia called low dose naltrexone (LDN). These are the original studie…

Mar 14, 2021 · 5 shares · 419 followers View post →
Dr. Sean Mackey
@DrSeanMackey · X

I mentioned a novel treatment we studied for fibromyalgia called low dose naltrexone (LDN). These are the original studies we did on this safe, effective and cheap drug. https://t.co/5vqaRZJ1B4 & https://t.co/OL8VzCNzny

Mar 13, 2021 · 16 likes · 5 shares · 8,182 followers View post →
Appalachian Wellness
@AppWellness · X

New post (Fibromyalgia symptoms are reduced by low-dose naltrexone: a pilot study.) has been published on Appalachian Wellness - https://t.co/oBuldtu1Sf

Oct 22, 2019 · 22 followers View post →
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