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Discussions show strong support for the importance of DEC2 in sleep regulation, with examples like a mention of a mother and daughter thriving on minimal sleep, which underscores curiosity and relevance. The tone varies from technical references to speculative remarks about future applications, demonstrating both engagement with details and optimism about the study’s potential impact.
Most discussions support the idea that DEC2 gene mutations influence sleep duration, highlighting the study's significance.
The topics generate high interest, with references to potential applications and biological mechanisms.
Several posts delve into scientific details and implications, indicating active engagement.
The posts suggest that the research could have meaningful implications for understanding sleep regulation and potential therapies.
Well, so sci-fi aside, you just need a small base editor inside a BBB-penetrating AAV to knock in a SNP into something like DEC2. https://t.co/TtYisPNBwQ So technically this can be done. @scifri https://t.co/IXsjWdbjEq
@pdhsu Let's do it. We already know the target (DEC2). So the hard part is done. Right? Right?..... https://t.co/TtYisPNBwQ
For reference: The Transcriptional Repressor DEC2 Regulates Sleep Length in Mammals https://t.co/MzLCepxO6t
The Transcriptional Repressor DEC2 Regulates Sleep Length in Mammals
@SimpelAlpha @l4porte @pew_pew_peeeeew https://t.co/RayITtAK3e
3/ The seminal paper on DEC2 gene mutation regulating sleep in mammals https://t.co/aRv3Ex8z5c
This video examines how much sleep humans need, the effects of over- or under-sleeping, and how sleep regulation genes, like DEC2, influence sleep duration. Learn about the genetic basis of short sleep traits and their…
3/ The seminal paper on DEC2 gene mutation regulating sleep in mammals https://t.co/aRv3Ex8z5c
References: DOI; 10.1126/science.1174443. DOI; 10.1073/pnas.1801693115. DOI; 10.1016/j.isci.2022.103964.
https://t.co/cJgU9j58BE
The Transcriptional Repressor DEC2 Regulates Sleep Length in Mammals
RT @GardenerContext: @MrBallen New fav: DEC2 (Short Sleepers): Mutation: P385R Effect: Ability to function well on 4-6 hrs of sleep per nig…
@MrBallen New fav: DEC2 (Short Sleepers): Mutation: P385R Effect: Ability to function well on 4-6 hrs of sleep per night. Example: A mother and daughter who thrive on minimal sleep. Study: He Y, et al. (2009). "The transcriptional repressor DEC2 regulates sleep length in mammals." Science.
@waitbutwhy There are (a very small number of) people with naturally occurring mutations to DEC2 (6hrs) or ADRB1 (4hrs) genes that function normally with less average sleep. The body is capable of seems, it’s a matter of configuration. https://t.co/ofmSffeGTY https://t.co/HR8V9GfY7y
https://t.co/k0QFTdaVuU https://t.co/Kk4IcB55hS https://t.co/1fh0OJ2zhX
Well, so sci-fi aside, you just need a small base editor inside a BBB-penetrating AAV to knock in a SNP into something like DEC2. https://t.co/TtYisPNBwQ So technically this can be done. @scifri https://t.co/IXsjWdbjEq
@pdhsu Let's do it. We already know the target (DEC2). So the hard part is done. Right? Right?..... https://t.co/TtYisPNBwQ
@SimpelAlpha @l4porte @pew_pew_peeeeew https://t.co/RayITtAK3e
The Transcriptional Repressor DEC2 Regulates Sleep Length in Mammals https://t.co/HOar0voHmx
Well, if you are interested to go through the scientific literature explaining the role of DEC2 transcriptional repressor in regulating the sleep length in mammals, here I have given the DOI of the Science paper. [DOI: 10.1126/science.1174443] #sleep #gene @ScienceMagazine @CNN
The Transcriptional Repressor DEC2 Regulates Sleep Length in Mammals https://t.co/LmvKqTZmQP
@sciencemagazine Hi I found a mistake in the paper "The transcriptional repressor DEC2 regulates sleep length in mammals", I tried to contact with the mail for contact the author in question but I could not due to a DNS error. Please contact me for more info
For reference: The Transcriptional Repressor DEC2 Regulates Sleep Length in Mammals https://t.co/MzLCepxO6t
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