J Physiol November 2009 PMID 19736298

Resistance exercise-induced increases in putative anabolic hormones do not enhance muscle protein synthesis or intracellular signalling in young men.

Daniel W D West, Gregory W Kujbida, Daniel R Moore, Philip Atherton, Nicholas A Burd, Jan P Padzik, Michael De Lisio, Jason E Tang, Gianni Parise, Michael J Rennie, Steven K Baker, Stuart M Phillips

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Mentions

47
Peak: 6 in Nov 2025
across 4 sources since Mar 2020

Extended reach

347,010
potential audience

Total likes

407

Video views

14,711

Mentions per month

Mar 2020 – Dec 2025

Where it's discussed

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AI synopsis

What people are saying

The group's discussions reflect a nuanced understanding, with many expressing doubts about the role of anabolic hormones in muscle growth, supported by phrases like 'no relationship' and 'doubt that elevated T is a big deal', demonstrating skepticism. Additionally, references to multiple studies and detailed debates about mechanisms highlight a moderate level of deep engagement and interest, though the overall tone indicates the topic is of theoretical rather than immediate practical impact.

AgreementModerate agreement

Most discussions reflect skepticism toward the idea that hormonal spikes drive muscle growth, highlighting a consensus that hormones are not the main factor.

InterestModerate interest

Participants show moderate curiosity, with some questioning previous beliefs and exploring alternative mechanisms.

EngagementModerate engagement

Comments include references to related research, debates, and observations, indicating a moderate level of detailed engagement.

ImpactNeutral impact

The discussions suggest some influence on the ongoing understanding of muscle physiology, but are not groundbreaking enough to shift paradigms significantly.

Abstract in brief

  • The study found that brief increases in testosterone, growth hormone, and IGF-1 after resistance exercise do not actually boost muscle protein synthesis or key signaling pathways, meaning these hormone spikes aren't the main drivers of muscle growth post-exercise.
  • Both low and high hormone conditions resulted in similar increases in muscle protein synthesis after exercise, suggesting that factors other than hormonal surges are responsible for muscle building.
  • The research indicates that local muscle mechanisms, rather than systemic hormone increases, are likely more important for triggering muscle growth following resistance training.]

Top posts

Most liked on X and Bluesky
伊田暁人 IDA Akito, PhD
@akito_ida · X

昨日のホルモンのツイート関連して、 ①アームカールを単体で実施(LH) ②アームカールと下半身トレを組み合わせて実施(HH) で比較したときに運動後テストステロンは②の方が増えるが、上腕二頭筋の筋タンパク質合成は①も②も変わらないというものもあります。 https://t.co/yVm1YRUfQs (1/2) https://t.co/gNVXXrWJuM

Mar 9, 2023 · 33 likes · 6 shares · 22,576 followers View post →
OJSN
@iamojsn · X

Resistance exercise-induced increases in putative anabolic hormones do not enhance muscle protein synthesis or intracellular signalling in young men - PMC https://t.co/SDWHsWhOff

Nov 15, 2025 · 23 likes · 4 shares · 14,976 followers View post →
Stuart Phillips (he/him)
@mackinprof · X

@GDLeahy @EricRawsonPhD @ShawnArent @jploenneke @KristaAustin @ExphysPhD No relationship between those hormones or their ratios to LBM or strength change in RT program see https://t.co/l8yq5MqbI8 https://t.co/U8502ZhjeT https://t.co/pfAQll5TJF https://t.co/Rj8HV20uzj https://t.co/S5XxUUUrB0... and more from our group

Mar 6, 2020 · 10 likes · 2 shares · 56,051 followers View post →
OJSN
@iamojsn · X

「片腕は腕トレだけ、もう片腕は腕トレしたあとに脚トレしてホルモンドバドバ! これで脚トレした方の腕だけもっと筋肥大すんじゃね???wwww→しませんでした」 2009年(https://t.co/aHD7TR9yVA) みたいに色々な方法で検証されています。 見ての通り超意訳してるので、詳しくは論文をどうぞ。

Nov 15, 2025 · 10 likes · 1 share · 14,976 followers View post →
Stuart Phillips (he/him)
@mackinprof · X

in the hypertrophic process - https://t.co/abZ5ZjaDVT https://t.co/S5XxUUUrB0 (read first), https://t.co/U8502ZhjeT (read second), https://t.co/l8yq5MqbI8 (read third). And an interesting point-counterpoint: https://t.co/4zFSyVPbXN

Mar 20, 2020 · 7 likes · 2 shares · 56,051 followers View post →
MATER
@DtMater · X

الخُلاصة : تقدرون تاكلون كاربوهيدرات بعد التمرين ولا راح يقلّل من البناء العضلي

Jun 10, 2020 · 7 likes · 561 followers View post →

All mentions

わーろっく
@tubuyakkuma · X

RT @iamojsn: Resistance exercise-induced increases in putative anabolic hormones do not enhance muscle protein synthesis or intracellular s…

Nov 15, 2025 · 4 shares · 824 followers View post →
OJSN
@iamojsn · X

RT @iamojsn: 「片腕は腕トレだけ、もう片腕は腕トレしたあとに脚トレしてホルモンドバドバ! これで脚トレした方の腕だけもっと筋肥大すんじゃね???wwww→しませんでした」 2009年(https://t.co/aHD7TR9yVA) みたいに色々な方法で検証されて…

Nov 15, 2025 · 1 share · 14,976 followers View post →
麦ばたのほととぎす
@nekohototogisu · X

RT @iamojsn: Resistance exercise-induced increases in putative anabolic hormones do not enhance muscle protein synthesis or intracellular s…

Nov 15, 2025 · 4 shares · 535 followers View post →
OJSN
@iamojsn · X

「片腕は腕トレだけ、もう片腕は腕トレしたあとに脚トレしてホルモンドバドバ! これで脚トレした方の腕だけもっと筋肥大すんじゃね???wwww→しませんでした」 2009年(https://t.co/aHD7TR9yVA) みたいに色々な方法で検証されています。 見ての通り超意訳してるので、詳しくは論文をどうぞ。

Nov 15, 2025 · 10 likes · 1 share · 14,976 followers View post →
OJSN
@iamojsn · X

Resistance exercise-induced increases in putative anabolic hormones do not enhance muscle protein synthesis or intracellular signalling in young men - PMC https://t.co/SDWHsWhOff

Nov 15, 2025 · 23 likes · 4 shares · 14,976 followers View post →
文月宵(ケトン人)
@fumizukishou_bc · X

“抵抗運動によって誘発される推定同化ホルモンの増加は、若い男性の筋肉タンパク質合成や細胞内シグナル伝達を促進しない” 上腕二頭筋での研究 テストステロンやヒト成長ホルモンは筋力トレーニングの筋肥大メカニズムには寄与しなかった 低負荷高回数でも肥大するからね https://t.co/gAD6HdNmn6

Jul 10, 2025 · 2 likes · 736 followers View post →
TGT_Taro
@TGT_Taro · X

RT @akito_ida: 昨日のホルモンのツイート関連して、 ①アームカールを単体で実施(LH) ②アームカールと下半身トレを組み合わせて実施(HH) で比較したときに運動後テストステロンは②の方が増えるが、上腕二頭筋の筋タンパク質合成は①も②も変わらないというものもあ…

Mar 11, 2025 · 6 shares · 359 followers View post →
なべ
@nabe_s130 · X

RT @akito_ida: 昨日のホルモンのツイート関連して、 ①アームカールを単体で実施(LH) ②アームカールと下半身トレを組み合わせて実施(HH) で比較したときに運動後テストステロンは②の方が増えるが、上腕二頭筋の筋タンパク質合成は①も②も変わらないというものもあ…

Mar 11, 2025 · 6 shares · 265 followers View post →
伊田暁人 IDA Akito, PhD
@akito_ida · X

RT @akito_ida: 昨日のホルモンのツイート関連して、 ①アームカールを単体で実施(LH) ②アームカールと下半身トレを組み合わせて実施(HH) で比較したときに運動後テストステロンは②の方が増えるが、上腕二頭筋の筋タンパク質合成は①も②も変わらないというものもあ…

Mar 11, 2025 · 6 shares · 22,576 followers View post →
Oleg A. Chagin
@Oleg_A_Chagin · X

Resistance exercise-induced increases in putative anabolic hormones do not enhance muscle protein synthesis or intracellular signalling in young men - PMC https://t.co/l0CFzktPnb

Jun 19, 2023 · 1,133 followers View post →
Percy
@rusfiliri115100 · X

RT @stan_nikolov1: https://t.co/RaYiVYwRNZ West et al 2009. Would it have made a difference if the leg training was before the arm training…

Jun 19, 2023 · 1 share View post →
蘭暴⏳
@4TtDeherI8HcRt9 · X

RT @bloc_samurai: 昨日のホルモンのツイート関連して、 ①アームカールを単体で実施(LH) ②アームカールと下半身トレを組み合わせて実施(HH) で比較したときに運動後テストステロンは②の方が増えるが、上腕二頭筋の筋タンパク質合成は①も②も変わらないというも…

Mar 9, 2023 · 6 shares · 290 followers View post →
万年猫 @ナンジャ大隊ネコ中隊所属
@mannenneko · X

RT @bloc_samurai: 昨日のホルモンのツイート関連して、 ①アームカールを単体で実施(LH) ②アームカールと下半身トレを組み合わせて実施(HH) で比較したときに運動後テストステロンは②の方が増えるが、上腕二頭筋の筋タンパク質合成は①も②も変わらないというも…

Mar 9, 2023 · 6 shares · 330 followers View post →
伊田暁人 IDA Akito, PhD
@akito_ida · X

昨日のホルモンのツイート関連して、 ①アームカールを単体で実施(LH) ②アームカールと下半身トレを組み合わせて実施(HH) で比較したときに運動後テストステロンは②の方が増えるが、上腕二頭筋の筋タンパク質合成は①も②も変わらないというものもあります。 https://t.co/yVm1YRUfQs (1/2) https://t.co/gNVXXrWJuM

Mar 9, 2023 · 33 likes · 6 shares · 22,576 followers View post →
しょう
@fitness_Labo · X

実は運動後の成長ホルモン分泌は筋肥大にあまり関与せず血糖値維持に働きます。 アメリカなどではトレーニング後はタンパク質補給でなく血糖値低下から糖新生が起きるのを防ぐため、糖質補給が主流となってきています。 https://t.co/54gFmxrfI6

Jul 24, 2021 · 562 followers View post →
Stuart Phillips (he/him)
@mackinprof · X

@SimpliFaster No role for anabolic hormones in this process... really absolutely none: https://t.co/clOLoCNhoP https://t.co/L1mi8jV01I https://t.co/D7h9lQgIab https://t.co/iMULMRO1c9

May 24, 2021 · 3 likes · 56,051 followers View post →
Bhopender Thakur
@TheBhupiThakur · X

RT @mackinprof: @NanciGuestRDPhD @livereater2 @shameermulji @PedantDog @Nomzobo @gosharpshooter I doubt that elevated T is a big deal. htt…

Jan 21, 2021 · 2 shares · 1,393 followers View post →
Marcus Wolford
@mvmntcoach · X

RT @mackinprof: @NanciGuestRDPhD @livereater2 @shameermulji @PedantDog @Nomzobo @gosharpshooter I doubt that elevated T is a big deal. htt…

Jan 20, 2021 · 2 shares · 2,420 followers View post →
Stuart Phillips (he/him)
@mackinprof · X

@NanciGuestRDPhD @livereater2 @shameermulji @PedantDog @Nomzobo @gosharpshooter I doubt that elevated T is a big deal. https://t.co/D7h9lQgIab https://t.co/vLlvhoBqvd https://t.co/clOLoCNhoP https://t.co/iMULMRO1c9

Jan 20, 2021 · 5 likes · 2 shares · 56,051 followers View post →
MATER
@DtMater · X

الخُلاصة : تقدرون تاكلون كاربوهيدرات بعد التمرين ولا راح يقلّل من البناء العضلي

Jun 10, 2020 · 7 likes · 561 followers View post →
Roberto Bonilla
@bonillarob · X

RT @mackinprof: in the hypertrophic process - https://t.co/abZ5ZjaDVT https://t.co/S5XxUUUrB0 (read first), https://t.co/U8502ZhjeT (read s…

Mar 21, 2020 · 2 shares · 708 followers View post →
Stuart Phillips (he/him)
@mackinprof · X

in the hypertrophic process - https://t.co/abZ5ZjaDVT https://t.co/S5XxUUUrB0 (read first), https://t.co/U8502ZhjeT (read second), https://t.co/l8yq5MqbI8 (read third). And an interesting point-counterpoint: https://t.co/4zFSyVPbXN

Mar 20, 2020 · 7 likes · 2 shares · 56,051 followers View post →
Ema.pf
@BlackStrongOk · X

RT @mackinprof: @GDLeahy @EricRawsonPhD @ShawnArent @jploenneke @KristaAustin @ExphysPhD No relationship between those hormones or their ra…

Mar 6, 2020 · 2 shares · 53 followers View post →
Eric Rawson, Ph.D.
@EricRawsonPhD · X

RT @mackinprof: @GDLeahy @EricRawsonPhD @ShawnArent @jploenneke @KristaAustin @ExphysPhD No relationship between those hormones or their ra…

Mar 6, 2020 · 2 shares · 7,523 followers View post →
Stuart Phillips (he/him)
@mackinprof · X

@GDLeahy @EricRawsonPhD @ShawnArent @jploenneke @KristaAustin @ExphysPhD No relationship between those hormones or their ratios to LBM or strength change in RT program see https://t.co/l8yq5MqbI8 https://t.co/U8502ZhjeT https://t.co/pfAQll5TJF https://t.co/Rj8HV20uzj https://t.co/S5XxUUUrB0... and more from our group

Mar 6, 2020 · 10 likes · 2 shares · 56,051 followers View post →
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