February 2010 PMID 19845667

Reduction in the appearance of facial hyperpigmentation after use of moisturizers with a combination of topical niacinamide and N-acetyl glucosamine: results of a randomized, double-blind, vehicle-controlled trial.

A B Kimball, J R Kaczvinsky, J Li, L R Robinson, P J Matts, C A Berge, K Miyamoto, D L Bissett

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Mentions

Peak: 4 in Oct 2023

across 3 sources since Jun 2022

Extended reach

1,220,625

potential audience

Total likes

23,758

Video views

1,217,960

Mentions per month

Jun 2022 – Aug 2024

Where it's discussed

X / Twitter6 posts
Facebook3 posts
YouTube2 videos

AI synopsis

What people are saying

The group generally shows agreement with the article, as seen in comments about the study’s promising results; interest is conveyed through mentions of hyperpigmentation and skin brightening benefits, while engagement is high in posts that elaborate on ingredients like niacinamide and glucosamine, suggesting the research’s influence on personal skincare choices and industry perspectives.

AgreementModerate agreement

Most discussions acknowledge the positive findings of the study, with some expressing agreement or sharing similar views about the effectiveness of the combination treatment.

InterestModerate interest

There is a moderate level of interest, with some posts linking to the potential benefits for skin issues like hyperpigmentation and emphasizing the relevance of the results.

EngagementHigh engagement

Many posts actively discuss the mechanisms and results, with some sharing personal recommendations and insights, indicating deep engagement.

ImpactModerate impact

The discussions suggest that users believe this research could influence skincare routines and product development, reflecting a modest but notable perceived impact.

Abstract in brief

The study found that a topical moisturizer containing both niacinamide and N-acetyl glucosamine (NAG) significantly reduced facial hyperpigmentation in women aged 40-60 over 10 weeks, compared to a control formulation without these ingredients.
Multiple measures, including digital imaging and expert assessment, showed that the combination formulation was more effective at decreasing visible pigmentation and melanin spots than the vehicle control, with results being statistically significant (p ≤ .005).
The findings suggest that this combination skincare product not only offers protection with SPF 15 sunscreen but also improves irregular pigmentation and hypermelanization beyond what sunscreen alone can achieve.]

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All mentions

Effective Tyrosinase Inhibition with Thiamidol for Melasma Treatment

Melasma causes dark patches on the face and can be challenging to treat. A study comparing Thiamidol with hydroquinone shows Thiamidol leads to significant skin pigmentation improvement after 12 weeks, with good…

ingck · Jul 24, 2022 782,213 views

Efficacy of Niacinamide and N-Acetyl Glucosamine in Reducing Facial Hyperpigmentation

This study demonstrates that a moisturizer containing niacinamide and N-acetyl glucosamine significantly reduces facial hyperpigmentation in women aged 40-60 over 10 weeks, outperforming a control formulation.

ingck · Oct 29, 2023 435,747 views

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