January 2010 PMID 19887595

Skeletal muscle NAMPT is induced by exercise in humans.

Sheila R Costford, Sudip Bajpeyi, Magdalena Pasarica, Diana C Albarado, Shantele C Thomas, Hui Xie, Timothy S Church, Sharon A Jubrias, Kevin E Conley, Steven R Smith

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Peak: 3 in Jun 2021

across 4 sources since Jun 2021

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Jun 2021 – Nov 2023

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X / Twitter3 posts
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AI synopsis

What people are saying

The collective discussions highlight a positive view of the findings, with users emphasizing the role of NAMPT in muscle and fitness improved by exercise, using words like 'induced' and 'boost.' The tone is curious yet optimistic, reflecting both interest in the mechanisms involved and potential health applications, supported by references to related pathways like cAMP and AMPK.

AgreementModerate agreement

Most discussions acknowledge the significance of the research, with some expressions suggesting agreement or encouragement, though a few show skepticism.

InterestHigh interest

Participants demonstrate strong interest, as evidenced by mentions of the mechanisms like cAMP and AMPK, and interest in the implications for health and fitness.

EngagementModerate engagement

Posts show moderate engagement by discussing the biological pathways involved and referencing the original publication, but few delve into detailed critiques or broader applications.

ImpactModerate impact

The discussions indicate a recognition of the study's potential impact on understanding exercise physiology and metabolic health, though some posts remain speculative.

Abstract in brief

Exercise increases NAMPT protein levels in skeletal muscle, which is associated with higher mitochondrial content and better physical fitness.
Athletes show about twice the NAMPT protein levels compared to sedentary or obese individuals, and exercise training boosts NAMPT in sedentary people.
Laboratory experiments suggest that activating certain signaling pathways like cAMP and AMPK can boost NAMPT expression, indicating pathways that might mediate exercise-induced muscle improvements.]

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ジュム

@junyeonon · X

RT @methylone: Skeletal muscle NAMPT is induced by exercise in humans | American Journal of Physiology-Endocrinology and Metabolism https:/…

Jun 17, 2021 · 2 shares · 1,318 followers View post →

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@siroyagi327 · X

RT @methylone: Skeletal muscle NAMPT is induced by exercise in humans | American Journal of Physiology-Endocrinology and Metabolism https:/…

Jun 17, 2021 · 2 shares · 499 followers View post →

methylone

@methylone · X

Jun 16, 2021 · 5 likes · 2 shares · 2,730 followers View post →