Improving diffraction by humidity control: a novel device compatible with X-ray beamlines.

Juan Sanchez-Weatherby, Matthew W Bowler, Julien Huet, Alexandre Gobbo, Franck Felisaz, Bernard Lavault, Raphael Moya, Jan Kadlec, Raimond B G Ravelli, Florent Cipriani

December 2009 Acta Crystallogr D Biol Crystallogr

Synopsis of Social media discussions

The discussions reflect a recognition of the device's decade-long contribution to diffraction improvements, exemplified by phrases like 'It's 10 years since we published...' which convey a sense of milestone and appreciation. The tone is respectful and appreciative, indicating moderate interest, but there is little evidence of extensive technical debate or engagement with future developments.

A
Agreement
 Moderate agreement

Most discussions recognize the significance of the humidity control device and agree it's an important advancement in diffraction techniques.

I
Interest
 Moderate level of interest

Posts show moderate interest, with some expressing appreciation for the technology's longevity and potential but few delving into detailed analysis.

E
Engagement
 Neutral engagement

The commentary appears somewhat superficial, mostly noting anniversaries or general recognition without deep technical discussion.

I
Impact
 Moderate level of impact

Participants acknowledge the device's importance, but there is limited discussion of broader scientific implications or implementation challenges.

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4 Posts

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Extended Reach

72,397

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Posts referencing the article

Advanced Humidity Control Device Enhances Protein Crystal Diffraction

Advanced Humidity Control Device Enhances Protein Crystal Diffraction

This novel device precisely controls humidity around protein crystals during X-ray data collection. It allows quick setup, water content adjustment, dehydration monitoring, and easy cryocooling, improving diffraction quality in standard synchrotron beamlines.

International Union of Crystallography

October 14, 2013

176 views

Advanced Humidity Control Device Enhances Protein Crystal Diffraction

Advanced Humidity Control Device Enhances Protein Crystal Diffraction

A novel device allows precise humidity regulation around protein crystals during X-ray data collection. This improves crystal quality and diffraction properties, is quickly installable, and compatible with standard beamlines, facilitating post-crystallization optimization.

International Union of Crystallography

October 14, 2013

126 views

  • Analio Dugarte
    @analioj (Twitter)

    RT @moncourvoisier: It's 10 years since we published the humidity control device paper in @ActaCrystD
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    December 11, 2019

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  • Structural Chemistry
    @ActaCrystC (Twitter)

    RT @moncourvoisier: It's 10 years since we published the humidity control device paper in @ActaCrystD
    view full post

    December 5, 2019

    4

  • EMBL
    @embl (Twitter)

    RT @moncourvoisier: It's 10 years since we published the humidity control device paper in @ActaCrystD
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    December 4, 2019

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  • Matthew Bowler
    @moncourvoisier (Twitter)

    It's 10 years since we published the humidity control device paper in @ActaCrystD
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    December 4, 2019

    13

    4

  • Developments in X-ray Crystallographic Structure Determination of ...

    10.1107/S0907444909037822. Crossref · PubMed · Google Scholar. 11. Weik M., Ravelli R. B., Kryger G., McSweeney S., Raves M. L., Harel M., Gros ...
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    March 7, 2014

    News

Abstract Synopsis

  • A new device has been created to precisely control the humidity around protein crystals during X-ray data collection, making it easier to improve crystal quality for diffraction analysis.
  • The device is quick to set up, compatible with standard synchrotron beamlines, and allows researchers to adjust water content in crystals, monitor dehydration progress optically and through diffraction images, and then easily cryocool samples at the optimal hydration level.
  • Tested at ESRF beamlines, this humidity control tool offers a practical way to optimize crystal diffraction properties post-crystallization, which is otherwise difficult to reproduce and monitor.]