January 2010 PMID 20086073

Metabolic effects of fructose and the worldwide increase in obesity.

Luc Tappy, Kim-Anne Lê

Mentions

131
Peak: 7 in Sep 2021
across 5 sources since May 2020

Extended reach

201,005
potential audience

Total likes

165

Video views

3,486

Mentions per month

May 2020 – Jul 2025

Where it's discussed

  • News66 articles
  • X / Twitter32 posts
  • Facebook17 posts
  • Blogs12 articles
  • YouTube4 videos

AI synopsis

What people are saying

The discussions demonstrate strong support for the article's conclusions, with many posters citing the harmful effects of fructose on health conditions like obesity, diabetes, and even Alzheimer's, using emotionally charged language and references to scientific insights. The tone varies from supportive to skeptical, reflecting a broad spectrum of interest and engagement, with some participants advocating for policy changes and others sharing personal health journeys.

AgreementModerate agreement

Many discussions acknowledge the role of fructose in metabolic issues, with some emphasizing its contribution to obesity and related diseases, showing general support for the article's premise.

InterestHigh interest

The posts exhibit high engagement with the topic, with many referencing related health issues and opinions on sugar, indicating strong interest.

EngagementHigh engagement

Posts reflect deep engagement through multiple references to scientific concepts, health implications, and debates about dietary recommendations, including mentioning specific studies and personal experiences.

ImpactModerate impact

While several discussions emphasize the significance of fructose's effects on health and policy, some posts are more opinion-based, so the perceived overall impact, while notable, is moderate.

Abstract in brief

  • Fructose, a sugar now common in our diet from sources like high fructose corn syrup, fruits, and honey, metabolizes differently from glucose, mainly processed in the liver, which can lead to issues like insulin resistance, obesity, and fatty liver disease when consumed excessively, especially based on animal studies.
  • While high fructose intake has been linked to metabolic problems such as dyslipidemia and impaired insulin sensitivity in humans, the evidence is less clear at moderate consumption levels, and the role of fructose in the global obesity and metabolic disorder epidemic remains debated.
  • Concerns exist that free fructose in processed foods, especially from high fructose corn syrup, may cause more harm than natural fructose from fruits or sucrose, but definitive evidence is still lacking, highlighting the controversy over fructose’s contribution to health issues.

Top posts

Most liked on X and Bluesky
thalesnemo
@thalesnemo · X

@CarnivoreSapien @drmarkhyman @drandyphung Modern fruits are just toxic tree candies! @FructoseNo Humans evolved to eat ancient fruits for at most 2 weeks at the end of summer to fatten up for the coming winter! Not on hyper-sweet fruits ! The “Five a day” fairy story https://t.co/etT0rTdeb3➡️ https://t.co/kzr4EnWudL

Sep 19, 2021 · 24 likes · 7 shares · 1,115 followers View post →
Unacceptable Lisa ........Concerned Canadian
@LisaMar91564392 · X

@robertlufkinmd Chronically high consumption of fructose…it’s in almost every processed food… https://t.co/s9qqsKkWbe

Apr 11, 2023 · 23 likes · 3 shares · 6,441 followers View post →
Ed Livingston
@ehlJAMA · X

@tylerblack32 High quality research shows no difference in the effects of the two types of sugars. See Metabolic Effects of Fructose and the Worldwide Increase in Obesity Luc Tappy and Kim-Anne Lê 01 Jan 2010 https://t.co/opLsxQpTF9 https://t.co/r9DfRKC7XY Besides-the incidence of sugar https://t.co/rmIn1IMyXi

Nov 30, 2024 · 5 likes · 1 share · 10,795 followers View post →
JotaManifesto
@JotaManifesto · X

@JAVI__M_J @virginut Hola. Quizá Virginia haya que entender el contexto al que se refiera la persona que citas. Por todos es sabido las modificaciones del contenido de fructosa en las frutas. https://t.co/TxRKhPuNP7

May 30, 2020 · 4 likes · 5,099 followers View post →
Peri Dwyer Worrell
@dcperi · X

@DrPlantel https://t.co/7fLjyB3qOt

Nov 30, 2024 · 4 likes · 1 share · 656 followers View post →
thalesnemo
@thalesnemo · X

@REV_Insulin_Res @MigraineBook @realDaveFeldman I just keep eliminating foods and see if it helps. 1st it was wheat, then all grains,next potatoes,then leafy greens now berries too.Lost 20kg,no more arthritis,no more sinus issues,far far less GI issues . https://t.co/3c2B7RGdzA https://t.co/zbzAiuvA27 https://t.co/kzr4EnWudL

Apr 15, 2022 · 2 likes · 1,115 followers View post →

All mentions

Val Maylone
@MayloneVal · X

@kevinnbass https://t.co/xL4rJNSJJd

Jul 23, 2025 · 711 followers View post →
Joan Halcomb
@JoanHalcomb · X

RT @dcperi: @DrPlantel https://t.co/7fLjyB3qOt

Dec 1, 2024 · 1 share · 463 followers View post →
aMcD
@a_donna · X

RT @ehlJAMA: @tylerblack32 High quality research shows no difference in the effects of the two types of sugars. See Metabolic Effects of F…

Dec 1, 2024 · 1 share · 1,166 followers View post →
Ed Livingston
@ehlJAMA · X

@tylerblack32 High quality research shows no difference in the effects of the two types of sugars. See Metabolic Effects of Fructose and the Worldwide Increase in Obesity Luc Tappy and Kim-Anne Lê 01 Jan 2010 https://t.co/opLsxQpTF9 https://t.co/r9DfRKC7XY Besides-the incidence of sugar https://t.co/rmIn1IMyXi

Nov 30, 2024 · 5 likes · 1 share · 10,795 followers View post →
Peri Dwyer Worrell
@dcperi · X

@DrPlantel https://t.co/7fLjyB3qOt

Nov 30, 2024 · 4 likes · 1 share · 656 followers View post →
thalesnemo
@thalesnemo · X

@jarlebreivik @DoctorTro 2/N

Sep 2, 2024 · 1,115 followers View post →
thalesnemo
@thalesnemo · X

@PJeffcock @HarrySpoelstra Alzheimer’s is recently referred to as TYPE 3 DIABETES! https://t.co/Qqeq4Y1MnY ➡️ https://t.co/kzr4EnWudL ➡️ https://t.co/ckEajjXVKW ➡️ https://t.co/NaKTaSssfz

Jul 23, 2023 · 2 likes · 1,115 followers View post →
Hot As Ice
@kkaystronger · X

RT @LisaMar91564392: @robertlufkinmd Chronically high consumption of fructose…it’s in almost every processed food… https://t.co/s9qqsKkWbe

Apr 12, 2023 · 3 shares · 415 followers View post →
Jane Hay
@Hay0Jim · X

RT @LisaMar91564392: @robertlufkinmd Chronically high consumption of fructose…it’s in almost every processed food… https://t.co/s9qqsKkWbe

Apr 12, 2023 · 3 shares · 33,735 followers View post →
Seamus
@Seamus01952928 · X

RT @LisaMar91564392: @robertlufkinmd Chronically high consumption of fructose…it’s in almost every processed food… https://t.co/s9qqsKkWbe

Apr 11, 2023 · 3 shares · 1,524 followers View post →
Unacceptable Lisa ........Concerned Canadian
@LisaMar91564392 · X

@robertlufkinmd Chronically high consumption of fructose…it’s in almost every processed food… https://t.co/s9qqsKkWbe

Apr 11, 2023 · 23 likes · 3 shares · 6,441 followers View post →
Javi Ciborro
@papayaykware · X

https://t.co/dV9U9Pfk85

Mar 12, 2023 · 8,042 followers View post →
Jacob Gudiol
@JacobGudiol · X

https://t.co/weBxs16yrJ https://t.co/2zfPF6MeCz https://t.co/j3NwkwnOwh

Feb 6, 2023 · 1 like · 24,407 followers View post →
thalesnemo
@thalesnemo · X

@KearnsIlana @ElieJarrougeMD Sugars are SUGARS —PERIOD ! Modern fruits are just toxic tree candies! Too high in fructose and glucose! https://t.co/FlqRLgAB1s ➡️ https://t.co/Kry9Uyax9k ➡️ https://t.co/zbzAiuNaTF ➡️ https://t.co/kzr4EnESPb ➡️ https://t.co/nFNZ6GN9jE https://t.co/Gu2GlYRTIV

Aug 24, 2022 · 1 like · 1,115 followers View post →
thalesnemo
@thalesnemo · X

@themerl12 @ScepticalDoctor Modern fruits are just toxic tree candies! Too high in fructose & glucose. https://t.co/FlqRLgj09U ➡️ https://t.co/iBCfBjodaD ➡️@FructoseNo ➡️ https://t.co/nFNZ6Gvys6 ➡️ https://t.co/kzr4EnWudL https://t.co/HipuZQb2xX

Aug 24, 2022 · 1,115 followers View post →
thalesnemo
@thalesnemo · X

@REV_Insulin_Res @MigraineBook @realDaveFeldman I just keep eliminating foods and see if it helps. 1st it was wheat, then all grains,next potatoes,then leafy greens now berries too.Lost 20kg,no more arthritis,no more sinus issues,far far less GI issues . https://t.co/3c2B7RGdzA https://t.co/zbzAiuvA27 https://t.co/kzr4EnWudL

Apr 15, 2022 · 2 likes · 1,115 followers View post →
thalesnemo
@thalesnemo · X

@ScepticalDoctor Your comment is factually wrong ! There are NO essential dietary carbs needed in the human diet.Modern fruits are just toxic tree candies! 1️⃣ https://t.co/iNCVChQh5H 2️⃣ https://t.co/EZ54txCa1t 3️⃣ https://t.co/iBCfBjodaD 4️⃣ https://t.co/zbzAiuvA27 5️⃣ https://t.co/kzr4EnWudL

Nov 29, 2021 · 1,115 followers View post →
thalesnemo
@thalesnemo · X

@beibhinnbyrne @KenDBerryMD Modern fruits are just toxic tree candies! Too much fruit gave me a heart attack https://t.co/3c2B7RGdzA Why fruits are evil -sugar in fruit is bad for your health https://t.co/zbzAiuvA27 ➡️ https://t.co/kzr4EnWudL➡️ https://t.co/Qqeq4Y1MnY ➡️ https://t.co/YlpzwJN9XR https://t.co/eq3nl5ISlC

Nov 8, 2021 · 1,115 followers View post →
thalesnemo
@thalesnemo · X

@CarnivoreSapien @KenDBerryMD @AmerAcadPedDent Sugar independent of source will spur the same chemical reactions. Modern fruits ARE JUST TOXIC TREE CANDIES ! Why fruits are evil -sugar in fruit is bad for your health https://t.co/zbzAiuvA27 Metabolic effects of fructose on worldwide obesity epidemic https://t.co/kzr4EnWudL

Nov 7, 2021 · 1,115 followers View post →
✜Pawel
@Pawel45373005 · X

RT @thalesnemo: @CarnivoreSapien @drmarkhyman @drandyphung Modern fruits are just toxic tree candies! @FructoseNo Humans evolved to eat an…

Sep 20, 2021 · 7 shares · 81 followers View post →
Emmanuel Mendonça
@EmmanuelMStudio · X

RT @thalesnemo: @CarnivoreSapien @drmarkhyman @drandyphung Modern fruits are just toxic tree candies! @FructoseNo Humans evolved to eat an…

Sep 20, 2021 · 7 shares · 49 followers View post →
Tracey Ward ©️
@bantingbant · X

RT @thalesnemo: @CarnivoreSapien @drmarkhyman @drandyphung Modern fruits are just toxic tree candies! @FructoseNo Humans evolved to eat an…

Sep 19, 2021 · 7 shares · 497 followers View post →
Bela Kovacs
@bkovacs6 · X

RT @thalesnemo: @CarnivoreSapien @drmarkhyman @drandyphung Modern fruits are just toxic tree candies! @FructoseNo Humans evolved to eat an…

Sep 19, 2021 · 7 shares · 820 followers View post →
Giddey Gal
@giddeygirl · X

RT @thalesnemo: @CarnivoreSapien @drmarkhyman @drandyphung Modern fruits are just toxic tree candies! @FructoseNo Humans evolved to eat an…

Sep 19, 2021 · 7 shares · 3,043 followers View post →
Gary Fettke
@FructoseNo · X

RT @thalesnemo: @CarnivoreSapien @drmarkhyman @drandyphung Modern fruits are just toxic tree candies! @FructoseNo Humans evolved to eat an…

Sep 19, 2021 · 7 shares · 84,760 followers View post →
thalesnemo
@thalesnemo · X

@CarnivoreSapien @drmarkhyman @drandyphung Modern fruits are just toxic tree candies! @FructoseNo Humans evolved to eat ancient fruits for at most 2 weeks at the end of summer to fatten up for the coming winter! Not on hyper-sweet fruits ! The “Five a day” fairy story https://t.co/etT0rTdeb3➡️ https://t.co/kzr4EnWudL

Sep 19, 2021 · 24 likes · 7 shares · 1,115 followers View post →
thalesnemo
@thalesnemo · X

@mucueto @RobertLustigMD @elemental @Medium Modern fruits are just colorful toxic tree candies!1️⃣ https://t.co/Kry9UxSWhM 2️⃣ https://t.co/ZMAcCGCh0O 3️⃣ https://t.co/870ijNuOvb 4️⃣ https://t.co/kzr4EnWudL

Aug 26, 2021 · 1,115 followers View post →
Eve Beavers-Fain BSN MPH
@espacetimeNOT · X

this article spells it out nicely... @KevinH_PhD no point in research unless we can get the USDA to make some significant changes.... https://t.co/p4IbY5Rvca

Apr 22, 2021 · 1,204 followers View post →
thalesnemo
@thalesnemo · X

@trafficman30 @flufficat @DickPower369 Modern fruits are just tree candies! THEY ARE TOXIC! Hunans evolved to only eat fruits at end of summer only➡️ Why fruits are evil -sugar in fruit is bad for your health https://t.co/zbzAiuvA27 Metabolic effects of fructose on worldwide obesity epidemic https://t.co/kzr4EnWudL

Feb 13, 2021 · 1,115 followers View post →
thalesnemo
@thalesnemo · X

@trafficman30 @flufficat @DickPower369 2/ Metabolic effects of fructose on worldwide obesity epidemic https://t.co/kzr4EnWudL What is metabolic syndrome? -Dr ROBERT Lustig https://t.co/YlpzwJN9XR➡️ David Ludwick which comes first over eat(Why CICO does not work) references within the video https://t.co/9eqS3hgD8B

Feb 13, 2021 · 1,115 followers View post →
bioMioSoftware
@bioMioSoftware · X

RT @agingdoc1: Metabolic Effects of Fructose and the Worldwide Increase in Obesity 10 yrs old but pertinent. Fructose (HFCS) is incrimina…

Oct 22, 2020 · 102 followers View post →
JotaManifesto
@JotaManifesto · X

@JAVI__M_J @virginut Hola. Quizá Virginia haya que entender el contexto al que se refiera la persona que citas. Por todos es sabido las modificaciones del contenido de fructosa en las frutas. https://t.co/TxRKhPuNP7

May 30, 2020 · 4 likes · 5,099 followers View post →