The discussions demonstrate a high level of interest and engagement, as shown by references to primary studies like Wallace & Kelsey (2010) and Hansen et al. (2008), with posters debating exact reserve numbers and age-related decline. The tone reflects serious inquiry, supporting the conclusion that this research has important implications for understanding female reproductive health.
AgreementModerate agreement
Most discussions concur that the foundational studies and data align with the article's findings about ovarian reserve decline with age.
InterestHigh interest
The posts actively debate details like exact follicle counts and interpretations of data, showing high curiosity.
EngagementModerate engagement
Several posters reference specific studies, question sources, and clarify statistical nuances, indicating thoughtful engagement.
ImpactModerate impact
The discussions emphasize the importance of accurate ovarian reserve information for fertility planning, highlighting a moderate but meaningful impact.
Abstract in brief
This study created a model of how the number of nongrowing follicles (NGFs) in the human ovary changes from conception to menopause, showing that most women have very few NGFs by age 40, with only 3% of the original prebirth number remaining.
The model, based on data from multiple studies, indicates that about 81% of the variation in NGF levels is explained by age alone and highlights that NGF recruitment (progression toward maturity) peaks around age 14 before declining.
Understanding these age-related changes in ovarian reserve can improve fertility counseling and help women, including cancer survivors, better plan for their reproductive health.]
@HainSicht @UhOhApocalypse @StefanMolyneux What a convenient way to reframe what i said when you take away the context of their peak reproductive years.
I stand corrected, they lose 88% of their eggs at 30 & 97% at 40 compared to when they're in their peak reproductive years in their late teens.
https://t.co/4YnhVJMsHg
@koaleszenz Gotta love how none of the reporting on this study anywhere notes that half of the eggs are gone by 13 and 80% by 25
https://t.co/MuG1JbSHq2
@ibrahimcangezgn @dilsad genelleme isteginin cok kabarik oldugunu goruyorum ama verilere baktiginda yasla beraber azalan bir grafik raporlamislar.
Wallace, W. H. B. & Kelsey, T. W. (2010). Human ovarian reserve from conception to the menopause->bu zaten cocuk isteme ile tamamen alakasiz bir calisma(4/n)
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@vixmcintyre @_nomadic_soul Here are the sources:
Hansen et al. (2008):
https://t.co/98nxGoB2ih
PLOS ovarian reserve model:
https://t.co/CqVkWHYtZd
Both show ~30–50k follicles by age 30, not 100–150k or “hundreds of thousands.”
You’ve repeated those numbers but still haven’t provided a single source.
@Brittanshorr @_nomadic_soul Actually… the peer-reviewed data does put it around 30–50k at 30.
Hansen et al. (2008) – PLOS One – modelled ovarian reserve across age and shows the sharp decline from puberty → 30 → 40.
Here’s the study you asked for:
https://t.co/CqVkWHYtZd
@jbf789 @_nomadic_soul Here’s the primary study your own source is based on:
Wallace & Kelsey (2010), Human Ovarian Reserve from Conception to the Menopause
https://t.co/CqVkWHZ1OL
If you want to argue, argue with the data, not me.
@sofff1244 @16h53h @Jennah_e_ Human Ovarian Reserve from Conception to the Menopause (Wallace & Kelsey, 2010) — À partir de données histologiques (325 ovaires à différents âges, depuis le fœtus jusqu’à la ménopause), les auteurs estiment qu’à 30 ans, seules ≈ 12 % des follicules non‑mûrissants
@D_last_Freeman @MisolaofJesus It’s part of what perplexity gave me as evidence. The sharpest of them all is below. It clarifies that the research that led to that stat used eggs from dead women and older sick women. Why? Those were the only eggs they had access to.
https://t.co/rklMlQWTYJ
Proof below: https://t.co/4IQm3P1aEn
@HainSicht @UhOhApocalypse @StefanMolyneux What a convenient way to reframe what i said when you take away the context of their peak reproductive years.
I stand corrected, they lose 88% of their eggs at 30 & 97% at 40 compared to when they're in their peak reproductive years in their late teens.
https://t.co/4YnhVJMsHg
@ibrahimcangezgn @dilsad genelleme isteginin cok kabarik oldugunu goruyorum ama verilere baktiginda yasla beraber azalan bir grafik raporlamislar.
Wallace, W. H. B. & Kelsey, T. W. (2010). Human ovarian reserve from conception to the menopause->bu zaten cocuk isteme ile tamamen alakasiz bir calisma(4/n)
@sodakolik @sportmenkaa Wallace, W. H. B., & Kelsey, T. W. (2010). Human Ovarian Reserve from Conception to the Menopause. PLoS ONE, 5(1), e8772. biyolojik saatin hurafe olmadığını gösteren çalışma++
@SianChristinaK Yes, but 70% of them were gone before we reached puberty, and 80% before we turned 25. Egg decline is continuous from birth, so there's nothing magic about the age of 30
Pregnancy beyond age 30 also increases mutational load on eggs and sperm, increasing the likelihood of disease and disorder emergence. We have population control and dysgenic fertility measures in place.
Sources:
https://t.co/VyTxqL6la7
https://t.co/naqFOEZuFq
@koaleszenz Gotta love how none of the reporting on this study anywhere notes that half of the eggs are gone by 13 and 80% by 25
https://t.co/MuG1JbSHq2
RT @ReproRocks: #OvarianReserve refers to the lifetime supply of oocytes in a female's ovaries and is established before birth. It can vary…
Feb 5, 2019 · 1 share · 1,664 followersView post →
IB
I'm a Repro Biologist
@ReproRocks · X
#OvarianReserve refers to the lifetime supply of oocytes in a female's ovaries and is established before birth. It can vary widely between individuals and has been shown to correlate with age at menopause as shown in this paper https://t.co/0hXXFHBVzL
Feb 5, 2019 · 1 like · 1 share · 1,009 followersView post →
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