January 2010 PMID 20111701

Human ovarian reserve from conception to the menopause.

W Hamish B Wallace, Thomas W Kelsey

Mentions

47
Peak: 6 in Nov 2025
across 7 sources since Jun 2016

Extended reach

238,228
potential audience

Total likes

2,642

Video views

98,124

Mentions per month

Jun 2016 – Nov 2025

Where it's discussed

  • X / Twitter23 posts
  • News14 articles
  • YouTube3 videos
  • Instagram3 posts
  • Facebook2 posts
  • Reddit1 posts
  • Blogs1 articles

AI synopsis

What people are saying

The discussions demonstrate a high level of interest and engagement, as shown by references to primary studies like Wallace & Kelsey (2010) and Hansen et al. (2008), with posters debating exact reserve numbers and age-related decline. The tone reflects serious inquiry, supporting the conclusion that this research has important implications for understanding female reproductive health.

AgreementModerate agreement

Most discussions concur that the foundational studies and data align with the article's findings about ovarian reserve decline with age.

InterestHigh interest

The posts actively debate details like exact follicle counts and interpretations of data, showing high curiosity.

EngagementModerate engagement

Several posters reference specific studies, question sources, and clarify statistical nuances, indicating thoughtful engagement.

ImpactModerate impact

The discussions emphasize the importance of accurate ovarian reserve information for fertility planning, highlighting a moderate but meaningful impact.

Abstract in brief

  • This study created a model of how the number of nongrowing follicles (NGFs) in the human ovary changes from conception to menopause, showing that most women have very few NGFs by age 40, with only 3% of the original prebirth number remaining.
  • The model, based on data from multiple studies, indicates that about 81% of the variation in NGF levels is explained by age alone and highlights that NGF recruitment (progression toward maturity) peaks around age 14 before declining.
  • Understanding these age-related changes in ovarian reserve can improve fertility counseling and help women, including cancer survivors, better plan for their reproductive health.]

Top posts

Most liked on X and Bluesky
Mohammed Al-Rifai
@Mohammed_pill · X

الدراسات National Institutes of Health: Human Ovarian Reserve from Conception to the Menopause. cleveland clinic Advanced Maternal Age

Sep 1, 2024 · 8 likes · 41,142 followers View post →
Daemon Knight
@Daemon_Knight01 · X

@HainSicht @UhOhApocalypse @StefanMolyneux What a convenient way to reframe what i said when you take away the context of their peak reproductive years. I stand corrected, they lose 88% of their eggs at 30 & 97% at 40 compared to when they're in their peak reproductive years in their late teens. https://t.co/4YnhVJMsHg

Nov 20, 2025 · 7 likes · 955 followers View post →
ڪوُبَرٍ
@ors1725 · X

المصادر مقال #بيتينا_ارنديت https://t.co/YTRNIndiRB انخفاض عدد البويضات و تدهور جودتها https://t.co/OPjwU4uQKu

Feb 10, 2025 · 6 likes · 2,256 followers View post →
Edward Dutton
@jollyheretic · X

@CCbucko It's actually 12% - https://t.co/8AWGp3jfat

Jul 30, 2019 · 5 likes · 59,128 followers View post →
Nick Simmonds
@Diacritic · X

@koaleszenz Gotta love how none of the reporting on this study anywhere notes that half of the eggs are gone by 13 and 80% by 25 https://t.co/MuG1JbSHq2

Dec 9, 2019 · 3 likes · 984 followers View post →
Berker Demirel
@WhyNotBerker · X

@ibrahimcangezgn @dilsad genelleme isteginin cok kabarik oldugunu goruyorum ama verilere baktiginda yasla beraber azalan bir grafik raporlamislar. Wallace, W. H. B. & Kelsey, T. W. (2010). Human ovarian reserve from conception to the menopause->bu zaten cocuk isteme ile tamamen alakasiz bir calisma(4/n)

Aug 11, 2025 · 2 likes · 155 followers View post →

All mentions

Tech Web
@techwebclover · X

@vixmcintyre @_nomadic_soul Here are the sources: Hansen et al. (2008): https://t.co/98nxGoB2ih PLOS ovarian reserve model: https://t.co/CqVkWHYtZd Both show ~30–50k follicles by age 30, not 100–150k or “hundreds of thousands.” You’ve repeated those numbers but still haven’t provided a single source.

Nov 27, 2025 · 1 like · 132 followers View post →
Tech Web
@techwebclover · X

@Brittanshorr @_nomadic_soul Actually… the peer-reviewed data does put it around 30–50k at 30. Hansen et al. (2008) – PLOS One – modelled ovarian reserve across age and shows the sharp decline from puberty → 30 → 40. Here’s the study you asked for: https://t.co/CqVkWHYtZd

Nov 26, 2025 · 132 followers View post →
Tech Web
@techwebclover · X

@jbf789 @_nomadic_soul Here’s the primary study your own source is based on: Wallace & Kelsey (2010), Human Ovarian Reserve from Conception to the Menopause https://t.co/CqVkWHZ1OL If you want to argue, argue with the data, not me.

Nov 26, 2025 · 132 followers View post →
Yassine
@YayaElouan · X

@sofff1244 @16h53h @Jennah_e_ Human Ovarian Reserve from Conception to the Menopause (Wallace & Kelsey, 2010) — À partir de données histologiques (325 ovaires à différents âges, depuis le fœtus jusqu’à la ménopause), les auteurs estiment qu’à 30 ans, seules ≈ 12 % des follicules non‑mûrissants

Nov 26, 2025 · 56 followers View post →
Oluwaseyi Kikiowo
@oluwaseyikiki · X

@D_last_Freeman @MisolaofJesus It’s part of what perplexity gave me as evidence. The sharpest of them all is below. It clarifies that the research that led to that stat used eggs from dead women and older sick women. Why? Those were the only eggs they had access to. https://t.co/rklMlQWTYJ Proof below: https://t.co/4IQm3P1aEn

Nov 25, 2025 · 1 like · 390 followers View post →
Daemon Knight
@Daemon_Knight01 · X

@HainSicht @UhOhApocalypse @StefanMolyneux What a convenient way to reframe what i said when you take away the context of their peak reproductive years. I stand corrected, they lose 88% of their eggs at 30 & 97% at 40 compared to when they're in their peak reproductive years in their late teens. https://t.co/4YnhVJMsHg

Nov 20, 2025 · 7 likes · 955 followers View post →
Berker Demirel
@WhyNotBerker · X

@ibrahimcangezgn @dilsad genelleme isteginin cok kabarik oldugunu goruyorum ama verilere baktiginda yasla beraber azalan bir grafik raporlamislar. Wallace, W. H. B. & Kelsey, T. W. (2010). Human ovarian reserve from conception to the menopause->bu zaten cocuk isteme ile tamamen alakasiz bir calisma(4/n)

Aug 11, 2025 · 2 likes · 155 followers View post →
ibrahimcangezginn
@ibrahimcangezgn · X

@sodakolik @sportmenkaa Wallace, W. H. B., & Kelsey, T. W. (2010). Human Ovarian Reserve from Conception to the Menopause. PLoS ONE, 5(1), e8772. biyolojik saatin hurafe olmadığını gösteren çalışma++

Aug 11, 2025 · 72 followers View post →
ڪوُبَرٍ
@ors1725 · X

المصادر مقال #بيتينا_ارنديت https://t.co/YTRNIndiRB انخفاض عدد البويضات و تدهور جودتها https://t.co/OPjwU4uQKu

Feb 10, 2025 · 6 likes · 2,256 followers View post →
Mohammed Al-Rifai
@Mohammed_pill · X

الدراسات National Institutes of Health: Human Ovarian Reserve from Conception to the Menopause. cleveland clinic Advanced Maternal Age

Sep 1, 2024 · 8 likes · 41,142 followers View post →
MGTOW
@aborashd141 · X

@noorh_174 https://t.co/6vn27wwSnb

May 16, 2022 · 7,194 followers View post →
MGTOW
@aborashd141 · X

@Mk18999236 https://t.co/6vn27wwSnb تفضل حبيبي https://t.co/VqfO7fjjm9 وهذا الثاني

May 15, 2022 · 7,194 followers View post →
Noor Siddiqui
@noor_siddiqui_ · X

Menopause is at 50 on average https://t.co/wXKzM33B0v

Feb 1, 2022 · 1 like · 14,619 followers View post →
alecia lynn eberhardt-smith
@alecialynn · X

@Astraea_Muse @BadMedicalTakes https://t.co/8rsO6rASke

Jul 21, 2021 · 1,556 followers View post →
Indian Agriculture
@km75singh · X

Do children before its too late https://t.co/nBpMhZjNON

Feb 8, 2020 · 288 followers View post →
Surf Rock and Twinkling Bells
@fibbyccino · X

@SianChristinaK Yes, but 70% of them were gone before we reached puberty, and 80% before we turned 25. Egg decline is continuous from birth, so there's nothing magic about the age of 30

Dec 10, 2019 · 1 like · 300 followers View post →
GangAnglo
@GangAnglo · X

Pregnancy beyond age 30 also increases mutational load on eggs and sperm, increasing the likelihood of disease and disorder emergence. We have population control and dysgenic fertility measures in place. Sources: https://t.co/VyTxqL6la7 https://t.co/naqFOEZuFq

Dec 10, 2019 · 9 followers View post →
Nick Simmonds
@Diacritic · X

@koaleszenz Gotta love how none of the reporting on this study anywhere notes that half of the eggs are gone by 13 and 80% by 25 https://t.co/MuG1JbSHq2

Dec 9, 2019 · 3 likes · 984 followers View post →
Nick
@NMaterazzo · X

@AlexDropkin @boxofmillipedes @mrgracemugabe @StefanMolyneux https://t.co/vlwFX2RoJ2

Dec 9, 2019 · 357 followers View post →
Shoppe Minuette
@shoppeminuette · X

@Bannondorf1 @starlightswifft @StefanMolyneux https://t.co/YNpYkdm4od that’s the OG study

Jul 31, 2019 · 167 followers View post →
Edward Dutton
@jollyheretic · X

@CCbucko It's actually 12% - https://t.co/8AWGp3jfat

Jul 30, 2019 · 5 likes · 59,128 followers View post →
Dr. Erin Williams
@DrErinWill · X

RT @ReproRocks: #OvarianReserve refers to the lifetime supply of oocytes in a female's ovaries and is established before birth. It can vary…

Feb 5, 2019 · 1 share · 1,664 followers View post →
I'm a Repro Biologist
@ReproRocks · X

#OvarianReserve refers to the lifetime supply of oocytes in a female's ovaries and is established before birth. It can vary widely between individuals and has been shown to correlate with age at menopause as shown in this paper https://t.co/0hXXFHBVzL

Feb 5, 2019 · 1 like · 1 share · 1,009 followers View post →
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