Ann N Y Acad Sci April 2010 PMID 20398008

Effects of sleep and circadian rhythm on the human immune system.

Tanja Lange, Stoyan Dimitrov, Jan Born

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Peak: 2 in Jan 2024

across 4 sources since Feb 2020

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What people are saying

The discussions reflect a strong consensus on the significance of sleep in immune function, with mentions of hormonal influences and clinical implications, such as the role of sleep modulation in diseases like COVID-19. The tone indicates curiosity and recognition of the research's relevance, evidenced by phrases like 'big impact,' 'clinical course,' and references to specific immune components like cytokines and immune cell activity.

AgreementModerate agreement

Most posts acknowledge the importance of sleep and circadian rhythms in immune regulation, aligning with the article's findings.

InterestHigh interest

Posts show high interest, discussing specific immune mechanisms and clinical implications, which indicates engagement with the research's relevance.

EngagementModerate engagement

Several comments reference detailed biological processes, clinical applications, and research challenges, demonstrating thoughtful engagement.

ImpactModerate impact

Discussion hints at the potential for altering health strategies and treatments based on sleep–immune interactions, suggesting a moderate impact.

Abstract in brief

Multiple immune parameters in human blood fluctuate over a 24-hour period, influenced by the circadian system and sleep.
During nighttime sleep, there's a peak in naive T cells and proinflammatory cytokines like IL12, while daytime peaks include antiinflammatory cytokines like IL10 and cytotoxic cells.
The circadian system and sleep work together, affecting hormones like cortisol, growth hormone, and prolactin, which in turn modulate immune responses and leukocyte traffic, especially promoting proinflammatory activity during sleep.]

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La Jefita

@soylajefita · X

facilitando la expansión clonal y generación de células de memoria (Lange, 2010) https://t.co/qF5vLGUl8e 16/

Apr 17, 2025 · 25 likes · 78,693 followers View post →

tune

@keisuke4713 · X

Sep 15, 2024 · 1 like · 3,746 followers View post →

TorstenAkesson

@TorstenAkesson · X

RT @JCedernaes: @TorstenAkesson @TomHedrup Ja man tror att det i sig har en stor betydelse (svårt att studera inverkan formellt hos människ…

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Jonathan Cedernaes

@JCedernaes · X

Jan 30, 2024 · 3 likes · 1 share · 3,126 followers View post →

Clusters of Biolearning

@CoBiolearning · X

Apr 17, 2020 · 1 like · 1 share · 81 followers View post →

David Manheim

@davidmanheim · X

@nlpnyc @MackayIM @kat_arden The evidence about how sleep matters for the immune system seems pretty clear. See, for example, https://t.co/Qq2w6ir32O and https://t.co/FOBWTSchwc

Feb 27, 2020 · 9,787 followers View post →