July 2010 PMID 20592293

Adverse events associated with testosterone administration.

Shehzad Basaria, Andrea D Coviello, Thomas G Travison, Thomas W Storer, Wildon R Farwell, Alan M Jette, Richard Eder, Sharon Tennstedt, Jagadish Ulloor, Anqi Zhang, Karen Choong, Kishore M Lakshman, Norman A Mazer, Renee Miciek, Joanne Krasnoff

Mentions

6
Peak: 1 in Oct 2020
across 2 sources since Oct 2020

Extended reach

1,824
potential audience

Total likes

3

Video views

17

Mentions per month

Oct 2020 – May 2025

Where it's discussed

  • X / Twitter4 posts
  • YouTube2 videos

AI synopsis

What people are saying

The social discussions demonstrate a balanced concern about testosterone treatment, with some posts highlighting the potential for improved muscle strength and the associated cardiovascular risks, using words like 'better performance' and 'safety concerns.' Others call for regulation, emphasizing cautious use, which reflects engagement with the real-world implications of the research.

AgreementModerate agreement

Most discussions acknowledge the study's findings about the risks and benefits of testosterone use, indicating moderate agreement with cautious perspectives.

InterestHigh interest

The topic sparks high interest, as reflected in the engagement with studies showing both the functional benefits and safety concerns.

EngagementModerate engagement

Participants delve into details, referencing specific studies, safety implications, and societal opinions, showing moderate but meaningful engagement.

ImpactModerate impact

The discussions highlight potential changes in clinical or social approaches to testosterone therapy, indicating a moderate impact; some emphasize regulation and safety.

Abstract in brief

  • Testosterone supplementation can improve muscle strength and physical function in older men but may pose safety risks.
  • In a study of men aged 65 and older with mobility issues, those using testosterone gel experienced significantly more cardiovascular-related adverse events than those using a placebo, leading to early trial termination.
  • Despite some functional benefits, the increased risk of serious heart and other adverse events suggests caution when considering testosterone treatment for older men with chronic health conditions.

Top posts

Most liked on X and Bluesky
koureiigaku
@koureiigaku · X

高齢男性にテストステロン等を16週間用いたHORMA試験*ではLBMと筋力、身体機能の増加が報告されましたが、より長くテストステロンを用いた他の試験*ではそれらに対する持続的改善は見られず、安全性への懸念が示されました。 https://t.co/uyCj84VMvb https://t.co/kQrAIm3oZx https://t.co/4O311a4HKo

Mar 1, 2021 · 2 likes · 853 followers View post →
Dr. Nitin Bharadwaj
@MedDiariesyt · X

@Genesneed @knappaste @E_Rex_Shawn @_joebrandon_ @patrickbetdavid Before you ask for sources, here they are. Katzung's Clinical Pharmacology 14th ed. Pg 740-743, Basaria S et al: Adverse events associated with testosterone administration. NEJM 2010;363:109

Jun 26, 2023 · 1 like · 372 followers View post →
Moisés
@moisesv · X

Hasta la testosterona debe ser algo regulado y no tanto maximizado. Puede no ser saludable a ciertos niveles. https://t.co/9ZTN3EnxFy

Oct 12, 2020 · 538 followers View post →
Cychem
@Cychem · X

Research suggests that when testosterone steroids are given to older men with mobility issues cardiovascular issues can result. However, in this study, the participants who received the drug performed better on leg and chest presses. https://t.co/g44enQzc0m

Nov 6, 2020 · 45 followers View post →

All mentions

Dr. Nitin Bharadwaj
@MedDiariesyt · X

@Genesneed @knappaste @E_Rex_Shawn @_joebrandon_ @patrickbetdavid Before you ask for sources, here they are. Katzung's Clinical Pharmacology 14th ed. Pg 740-743, Basaria S et al: Adverse events associated with testosterone administration. NEJM 2010;363:109

Jun 26, 2023 · 1 like · 372 followers View post →
koureiigaku
@koureiigaku · X

高齢男性にテストステロン等を16週間用いたHORMA試験*ではLBMと筋力、身体機能の増加が報告されましたが、より長くテストステロンを用いた他の試験*ではそれらに対する持続的改善は見られず、安全性への懸念が示されました。 https://t.co/uyCj84VMvb https://t.co/kQrAIm3oZx https://t.co/4O311a4HKo

Mar 1, 2021 · 2 likes · 853 followers View post →
Cychem
@Cychem · X

Research suggests that when testosterone steroids are given to older men with mobility issues cardiovascular issues can result. However, in this study, the participants who received the drug performed better on leg and chest presses. https://t.co/g44enQzc0m

Nov 6, 2020 · 45 followers View post →
Moisés
@moisesv · X

Hasta la testosterona debe ser algo regulado y no tanto maximizado. Puede no ser saludable a ciertos niveles. https://t.co/9ZTN3EnxFy

Oct 12, 2020 · 538 followers View post →