高齢男性にテストステロン等を16週間用いたHORMA試験*ではLBMと筋力、身体機能の増加が報告されましたが、より長くテストステロンを用いた他の試験*ではそれらに対する持続的改善は見られず、安全性への懸念が示されました。 https://t.co/uyCj84VMvb https://t.co/kQrAIm3oZx https://t.co/4O311a4HKo
Adverse events associated with testosterone administration.
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Oct 2020 – May 2025Where it's discussed
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X / Twitter4 posts
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YouTube2 videos
AI synopsis
What people are saying
The social discussions demonstrate a balanced concern about testosterone treatment, with some posts highlighting the potential for improved muscle strength and the associated cardiovascular risks, using words like 'better performance' and 'safety concerns.' Others call for regulation, emphasizing cautious use, which reflects engagement with the real-world implications of the research.
Most discussions acknowledge the study's findings about the risks and benefits of testosterone use, indicating moderate agreement with cautious perspectives.
The topic sparks high interest, as reflected in the engagement with studies showing both the functional benefits and safety concerns.
Participants delve into details, referencing specific studies, safety implications, and societal opinions, showing moderate but meaningful engagement.
The discussions highlight potential changes in clinical or social approaches to testosterone therapy, indicating a moderate impact; some emphasize regulation and safety.
Abstract in brief
- Testosterone supplementation can improve muscle strength and physical function in older men but may pose safety risks.
- In a study of men aged 65 and older with mobility issues, those using testosterone gel experienced significantly more cardiovascular-related adverse events than those using a placebo, leading to early trial termination.
- Despite some functional benefits, the increased risk of serious heart and other adverse events suggests caution when considering testosterone treatment for older men with chronic health conditions.
Top posts
Most liked on X and Bluesky@Genesneed @knappaste @E_Rex_Shawn @_joebrandon_ @patrickbetdavid Before you ask for sources, here they are. Katzung's Clinical Pharmacology 14th ed. Pg 740-743, Basaria S et al: Adverse events associated with testosterone administration. NEJM 2010;363:109
Hasta la testosterona debe ser algo regulado y no tanto maximizado. Puede no ser saludable a ciertos niveles. https://t.co/9ZTN3EnxFy
Research suggests that when testosterone steroids are given to older men with mobility issues cardiovascular issues can result. However, in this study, the participants who received the drug performed better on leg and chest presses. https://t.co/g44enQzc0m
All mentions
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Risks and Benefits of Testosterone Therapy for Older Men
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@Genesneed @knappaste @E_Rex_Shawn @_joebrandon_ @patrickbetdavid Before you ask for sources, here they are. Katzung's Clinical Pharmacology 14th ed. Pg 740-743, Basaria S et al: Adverse events associated with testosterone administration. NEJM 2010;363:109
高齢男性にテストステロン等を16週間用いたHORMA試験*ではLBMと筋力、身体機能の増加が報告されましたが、より長くテストステロンを用いた他の試験*ではそれらに対する持続的改善は見られず、安全性への懸念が示されました。 https://t.co/uyCj84VMvb https://t.co/kQrAIm3oZx https://t.co/4O311a4HKo
Research suggests that when testosterone steroids are given to older men with mobility issues cardiovascular issues can result. However, in this study, the participants who received the drug performed better on leg and chest presses. https://t.co/g44enQzc0m
Hasta la testosterona debe ser algo regulado y no tanto maximizado. Puede no ser saludable a ciertos niveles. https://t.co/9ZTN3EnxFy
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