Biol Psychiatry September 2010 PMID 20673872

Epigenetic transmission of the impact of early stress across generations.

Tamara B Franklin, Holger Russig, Isabelle C Weiss, Johannes Gräff, Natacha Linder, Aubin Michalon, Sandor Vizi, Isabelle M Mansuy

Mentions

26
Peak: 1 in Jan 2021
across 5 sources since Jan 2021

Extended reach

2,156
potential audience

Total likes

12

Video views

2,079

Mentions per month

Jan 2021 – Nov 2025

Where it's discussed

  • Blogs12 articles
  • News8 articles
  • X / Twitter2 posts
  • YouTube2 videos
  • Facebook2 posts

AI synopsis

What people are saying

The group discusses the article enthusiastically, highlighting the significance of epigenetic mechanisms in stress transmission, as seen in their mention of DNA methylation in sperm and brain tissue. Words like 'impact,' 'pass down,' and 'mechanism' reveal a tone of curiosity and acknowledgment of the study's importance, reflecting both interest and belief in its potential influence.

AgreementModerate agreement

Most discussions show moderate to strong support for the idea that early stress can influence subsequent generations, reflected in positive tones and acceptance of the research findings.

InterestHigh interest

The social discussions indicate high curiosity about the topic, with users expressing interest in the implications and mechanisms involved in epigenetic inheritance.

EngagementModerate engagement

Participants reference specific aspects of the study, such as epigenetic mechanisms and behavioral effects, demonstrating active engagement and analytical commentary.

ImpactModerate impact

The discussions suggest recognition of the research's potential impact on understanding mental health and inheritance, though some posts remain speculative or focused on questions for future research.

Abstract in brief

  • Early life stress, such as maternal separation in mice, can lead to depression-like behaviors and changes in how animals respond to stress later in life.
  • These behavioral effects can be passed from parents to their offspring, especially through males who experienced early stress, even if they were raised normally afterward.
  • The study suggests that early stress causes changes in DNA methylation (an epigenetic mechanism) in the germline (sperm) and brain, which may underlie the transmission of stress-related behaviors across generations.

Top posts

Most liked on X and Bluesky
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@spcttrddsspr · X

@CheyckHilde @DalilBoubakeur https://t.co/fSuufVMRSt

Jan 30, 2021 · 1 like · 39 followers View post →
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@attached_app · X

Franklin, T. B., et al. (2010). Epigenetic transmission of the impact of early stress across generations. Biological Psychiatry, 68(5), 408–415. https://t.co/Tl8UpEhiYN

Nov 8, 2025 · 39 followers View post →

All mentions

Attached | Feel fear / anxiety in relationships?
@attached_app · X

Franklin, T. B., et al. (2010). Epigenetic transmission of the impact of early stress across generations. Biological Psychiatry, 68(5), 408–415. https://t.co/Tl8UpEhiYN

Nov 8, 2025 · 39 followers View post →
Garçon de la Discorde
@spcttrddsspr · X

@CheyckHilde @DalilBoubakeur https://t.co/fSuufVMRSt

Jan 30, 2021 · 1 like · 39 followers View post →