January 2011 PMID 20944644

Genotype-phenotype associations and human eye color.

Désirée White, Montserrat Rabago-Smith

Mentions

63
Peak: 12 in Aug 2023
across 5 sources since Jul 2019

Extended reach

15,895
potential audience

Total likes

317

Video views

9,947

Mentions per month

Jul 2019 – Dec 2025

Where it's discussed

  • TikTok29 posts
  • Reddit21 posts
  • News6 articles
  • X / Twitter5 posts
  • YouTube2 videos

AI synopsis

What people are saying

The discussions highlight the shift from viewing eye color as a straightforward trait, with posts mentioning that it 'does not follow the classical paths of inheritance' and that recent research 'shows blue is a recessive,' conveying both skepticism and curiosity. The tone reflects an appreciation for new insights and a recognition of the research's significance in understanding human genetic diversity.

AgreementModerate agreement

Most discussions acknowledge that eye color inheritance is complex, reflecting support for the publication's findings that challenge simple Mendelian models.

InterestHigh interest

Posts demonstrate high curiosity and engagement with the topic, especially with comments about how eye color inheritance is more complicated than once thought.

EngagementModerate engagement

Comments include references to how research advances alter traditional views, indicating a moderate depth of engagement with the genetic details.

ImpactModerate impact

The discussions suggest the publication influences understanding of genetics and human evolution, although directly practical implications are not deeply explored.

Abstract in brief

  • Eye color is not a simple inherited trait and involves complex genetic interactions, including epistasis and incomplete dominance, with about 16 genes contributing but mainly focusing on HERC2 and OCA2 on chromosome 15.
  • Variations in single nucleotide polymorphisms (SNPs) within these genes influence eye color by affecting the expression of the pigmentation gene OCA2, which is regulated by an intronic promoter in HERC2.
  • Individuals may exhibit different eye colors in each eye or have complete lack of pigmentation (ocular albinism), and these genetic variations have important implications for understanding human evolution and population differences.]

Top posts

Most liked on X and Bluesky
Birgitta Neher
@NeBirgitta · X

Genotype–phenotype associations and human eye color https://t.co/Q1WR9gYnNN.

May 17, 2022 · 2 likes · 2,775 followers View post →
Denis
@antizapret_info · X

@RiotFloppa @umka663 У голубоглазых родителей кареглазые дети могут быть, редко конечно, вроде как последние работы показывают, что за цвет отвечает не один ген ну и привет, мутации https://t.co/SOSoXnMFfN

Jun 15, 2025 · 2,149 followers View post →
Ale LB
@Alelobu · X

https://t.co/BLxWnl8GCl

Jul 27, 2019 · 318 followers View post →
Fletcher
@KeyOsc · X

@s4mueI_ "The early view that blue is a simple recessive has been repeatedly shown to be wrong..." https://t.co/N3MJdaFEjL https://t.co/gE9Au4EooM Although eye color is usually modeled as a simple, Mendelian trait, further research and observation has indicated... https://t.co/N3MJdaFEjL

Oct 10, 2024 · 121 followers View post →

All mentions

Denis
@antizapret_info · X

@RiotFloppa @umka663 У голубоглазых родителей кареглазые дети могут быть, редко конечно, вроде как последние работы показывают, что за цвет отвечает не один ген ну и привет, мутации https://t.co/SOSoXnMFfN

Jun 15, 2025 · 2,149 followers View post →
Fletcher
@KeyOsc · X

@s4mueI_ "The early view that blue is a simple recessive has been repeatedly shown to be wrong..." https://t.co/N3MJdaFEjL https://t.co/gE9Au4EooM Although eye color is usually modeled as a simple, Mendelian trait, further research and observation has indicated... https://t.co/N3MJdaFEjL

Oct 10, 2024 · 121 followers View post →
David Pelo
@DavidPelo8 · X

@Jamaica658 @FckYaStandardz “Although eye color is usually modeled as a simple, Mendelian trait, further research and observation has indicated that eye color does not follow the classical paths of inheritance” (https://t.co/KGsZN9kCiN)

Dec 18, 2022 · 26 followers View post →
Birgitta Neher
@NeBirgitta · X

Genotype–phenotype associations and human eye color https://t.co/Q1WR9gYnNN.

May 17, 2022 · 2 likes · 2,775 followers View post →
Ale LB
@Alelobu · X

https://t.co/BLxWnl8GCl

Jul 27, 2019 · 318 followers View post →
Micro Onde Algérie Iris | TikTok
TikTok

2011 Jan;56(1):5-7. doi: 10.1038/jhg.2010.126. . Para grabar el vídeo, utilicé un adaptador de @ilabcam .

Dec 12, 2025 View →
Dti Spoiled Rotten Theme Tutorial | TikTok
TikTok

doi: 10.1038/jhg.2010.126. . Para grabar el vídeo, utilicé un adaptador de @ilabcam . . . #ojo #pupila #iris #vision #microscopio #divulgar #divulgacion ...

Dec 12, 2025 View →
RATTY (@elvisametefe0) | TikTok
TikTok

doi: 10.1038/jhg.2010.126. . Para grabar el vídeo, utilicé un adaptador de @ilabcam . . . #ojo #pupila #iris #vision #microscopio #divulgar #divulgacion ...

Dec 12, 2025 View →
#reneesrealm | TikTok
TikTok

doi: 10.1038/jhg.2010.126. . Para grabar el vídeo, utilicé un adaptador de @ilabcam . . . #ojo #pupila #iris #vision #microscopio #divulgar #divulgacion ...

Dec 12, 2025 View →
nvm_grslls (@gracelislie) | TikTok
TikTok

doi: 10.1038/jhg.2010.126. . Para grabar el vídeo, utilicé un adaptador de @ilabcam . . . #ojo #pupila #iris #vision #microscopio #divulgar #divulgacion ...

Dec 12, 2025 View →
m ꨄ (@mkrprv_tt) | TikTok
TikTok

doi: 10.1038/jhg.2010.126. . Para grabar el vídeo, utilicé un adaptador de @ilabcam . . . #ojo #pupila #iris #vision #microscopio #divulgar #divulgacion ...

Dec 12, 2025 View →
Eye Color | PDF | Eye Color | Visual System
News

doi:10.1038/jhg.2010.126. PMID 20944644. 10. ^ No Single Gene For Eye Color, Researchers Prove. Sciencedaily.com (22 February 2007). Retrieved on 2011-12-23 ...

Dec 12, 2025 View →
Genética y Herencia | PDF
News

Asociaciones genotipo-fenotipo y color de ojos humanos. Revista de Genética Humana, 56, 5-7. http://dx.doi.org/10.1038/jhg.2010.126. 1.5: La ley de la ...

Dec 12, 2025 View →
SG 7 Chapter 6 | PDF | Wellness | Science & Mathematics
News

Genotype-phenotype associations and human. eye color. Journal of Human Genetics, 56, 5–7. http://dx.doi.org/10.1038/jhg.2010.126. 3. Kimball, J. W. (2011 ...

Dec 12, 2025 View →
The Idea and Practice of Reading | PDF | Second Language | Learning
News

https://doi.org/10.1038/jhg.2010.126. Willcutt, E. G., Betjemann, R. S., McGrath, L. M., Chhabildas, N. A., Olson, R. K., DeFries, J. C., et al. (2010) ...

Dec 12, 2025 View →
Modern Iridology - Modern - Iridology - Sarah - Donoghue | PDF
News

https://doi.org/10.1038/jhg.2010.126. OceanofPDF.com. FURTHER READING & RESOURCES. Professional associations. The Guild of Naturopathic Iridologists ...

Dec 12, 2025 View →
Aiura Saiki Sa | TikTok
TikTok

doi: 10.1038/jhg.2010.126. . Para grabar el vídeo, utilicé un adaptador de @ilabcam . . . #ojo #pupila #iris #vision #microscopio #divulgar ...

Dec 1, 2025 View →
Umn Wicked Interview | TikTok
TikTok

doi: 10.1038/jhg.2010.126. . Para grabar el vídeo, utilicé un adaptador de @ilabcam . . . #ojo #pupila #iris #vision #microscopio #divulgar ...

Dec 1, 2025 View →
I was today years old when I knew these two were together but ...
TikTok

doi: 10.1038/jhg.2010.126. . Para grabar el vídeo, utilicé un adaptador de @ilabcam . . . #ojo #pupila #iris #vision #microscopio #divulgar ...

Oct 17, 2025 View →
Programa de Incentivo: Una Historia Viral Divertida | TikTok
TikTok

doi: 10.1038/jhg.2010.126. . Para grabar el vídeo, utilicé un adaptador de @ilabcam . . . #ojo #pupila #iris #vision #microscopio #divulgar ...

Sep 28, 2025 View →
Observando Animales Bajo el Microscopio | TikTok
TikTok

doi: 10.1038/jhg.2010.126. . Para grabar el vídeo, utilicé un adaptador de @ilabcam . . . #ojo #pupila #iris #vision #microscopio #divulgar ...

Mar 26, 2025 View →
‼️FAKE WEAPON‼️ my trigger fingers crazy mb #fypシ #airsoft ...
TikTok

doi: 10.1038/jhg.2010.126. . Para grabar el vídeo, utilicé un adaptador de @ilabcam . . . #ojo #pupila #iris #vision #microscopio #divulgar ...

Mar 3, 2025 View →
#diseccion #ojo #bulboocular #cienciasdelasalud #docencia ...
TikTok

doi: 10.1038/jhg.2010.126. . Para grabar el vídeo, utilicé un adaptador de @ilabcam . . . #ojo #pupila #iris #vision #microscopio #divulgar ...

Feb 20, 2025 View →
Productos Saludables de HEB Recomendados por Nutrióloga | TikTok
TikTok

doi: 10.1038/jhg.2010.126. . Para grabar el vídeo, utilicé un adaptador de @ilabcam . . . #ojo #pupila #iris #vision #microscopio #divulgar ...

Jan 17, 2025 View →
Maquillaje Perfecto para Ojos Negros: Consejos y Tutorial | TikTok
TikTok

doi: 10.1038/jhg.2010.126. . Para grabar el vídeo, utilicé un adaptador de @ilabcam . . . #ojo #pupila #iris #vision #microscopio #divulgar ...

Dec 12, 2024 View →
El punto ciego natural del ojo y su descubrimiento | TikTok
TikTok

doi: 10.1038/jhg.2010.126. . Para grabar el vídeo, utilicé un adaptador de @ilabcam . . . #ojo #pupila #iris #vision #microscopio #divulgar ...

Sep 19, 2024 View →
Anatomía de la Caja Torácica: Huesos y Funciones | TikTok
TikTok

doi: 10.1038/jhg.2010.126. . Para grabar el vídeo, utilicé un adaptador de @ilabcam . . . #ojo #pupila #iris #vision #microscopio #divulgar ...

May 14, 2024 View →
Descubre las partes del ojo y su función | TikTok
TikTok

doi: 10.1038/jhg.2010.126. . Para grabar el vídeo, utilicé un adaptador de @ilabcam . . . #ojo #pupila #iris #vision #microscopio #divulgar ...

Apr 15, 2024 View →
OJO BAJO EL MICROSCOPIO
TikTok

... 10.1038/jhg.2010.126. . Para grabar el vídeo, utilicé un adaptador de @ilabcam . . . #ojo #pupila #iris #vision #microscopio #divulgar ...

Feb 7, 2024 View →
Manchas en el contorno de ojos. Ojeras pigmentadas #manchas ...
TikTok

doi: 10.1038/jhg.2010.126. . Para grabar el vídeo, utilicé un adaptador de @ilabcam . . . #ojo #pupila #iris #vision #microscopio #divulgar ...

Nov 20, 2023 View →
r/explainlikeimfive on Reddit: ELI5: 青い目が劣性遺伝子で、緑の目が ...
Reddit

PubMed: 19619260. White D, Rabago-Smith M. 遺伝子型-表現型の関連性と人間の目の色。J Hum Genet. 2011 Jan;56(1):5-7. doi: 10.1038/jhg.2010.126.

Aug 31, 2023 View →
ELI5:如果藍眼睛是隱性基因
Reddit

... and human eye color. J Hum Genet. 2011 Jan;56(1):5-7. doi: 10.1038/jhg.2010.126. Epub 2010 Oct 14. Review. PubMed: 20944644. [已刪除]. • 2 年前.

Aug 31, 2023 View →
ELI5: 파란 눈이 열성 유전자고 초록색 눈이 우성 유전자면 왜 파란 눈 ...
Reddit

doi: 10.1038/jhg.2010.126. Epub 2010 Oct 14. Review. PubMed: 20944644. [삭제됨]. • 2년 전.

Aug 31, 2023 View →
ELI5: Wenn blaue Augen ein rezessives Gen sind und grüne Augen ...
Reddit

... Augenfarbe. J Hum Genet. 2011 Jan;56(1):5-7. doi: 10.1038/jhg.2010.126. Epub 2010 Okt 14. Review. PubMed: 20944644. [gelöscht]. • vor 2 Jahren.

Aug 31, 2023 View →
Forklart enkelt: Hvis blå øyne er et recessivt gen og grønne øyne er ...
Reddit

J Hum Genet. 2011 Jan;56(1):5-7. doi: 10.1038/jhg.2010.126. Epub 2010 Oct 14. Review. PubMed: 20944644. [slettet]. • for 2 år siden.

Aug 31, 2023 View →
Kolay anlatım: Eğer mavi gözler çekinik gen, yeşil gözler baskın gen ...
Reddit

J Hum Genet. 2011 Ocak;56(1):5-7. doi: 10.1038/jhg.2010.126. Epub 2010 Ekim 14. Gözden geçirme. PubMed: 20944644. [silindi]. • 2 yıl önce.

Aug 31, 2023 View →
ELI5: If blue eyes are a recessive gene and green eyes are a ...
Reddit

... and human eye color. J Hum Genet. 2011 Jan;56(1):5-7. doi: 10.1038/jhg.2010.126. Epub 2010 Oct 14. Review. PubMed: 20944644. [deleted]. • 2y ago.

Aug 31, 2023 View →
ELI5: Agar neeli aankhein recessive gene hain aur hari aankhein ...
Reddit

... and human eye color. J Hum Genet. 2011 Jan;56(1):5-7. doi: 10.1038/jhg.2010.126. Epub 2010 Oct 14. Review. PubMed: 20944644. [मिटाया गया]. • 2 वर्ष ...

Aug 31, 2023 View →
ஐந்து வயசுப் பசங்களுக்கான விளக்கம்: நீலக் கண்கள் ...
Reddit

doi: 10.1038/jhg.2010.126. Epub 2010 Oct 14. Review. PubMed: 20944644. [நீக்கப்பட்டது]. • 2 ஆண்டுகளுக்கு முன்.

Aug 31, 2023 View →
简单来说:如果蓝眼睛是隐性基因,绿眼睛是显性基因,为什么蓝 ...
Reddit

... and human eye color. J Hum Genet. 2011 Jan;56(1):5-7. doi: 10.1038/jhg.2010.126. Epub 2010 Oct 14. Review. PubMed: 20944644. [已删除]. • 2年前.

Aug 31, 2023 View →
Объясни как пятилетке: если голубые глаза — рецессивный ген ...
Reddit

... color. J Hum Genet. 2011 Jan;56(1):5-7. doi: 10.1038/jhg.2010.126. Epub 2010 Oct 14. Review. PubMed: 20944644. [удалено]. • 2 г. назад.

Aug 31, 2023 View →
Carnosidades en los Ojos: ¿Qué Debes Saber? | TikTok
TikTok

doi: 10.1038/jhg.2010.126. . Para grabar el vídeo, utilicé un adaptador de @ilabcam . . . #ojo #pupila #iris #vision #microscopio #divulgar ...

Aug 24, 2023 View →
Haciendo el trend de ojos diferentes en TikTok | TikTok
TikTok

doi: 10.1038/jhg.2010.126. . Para grabar el vídeo, utilicé un adaptador de @ilabcam . . . #ojo #pupila #iris #vision #microscopio #divulgar ...

May 2, 2023 View →
ANTES Y DESPUES ‍⚕️ CIRUGÍA DE CATARARA POR ...
TikTok

doi: 10.1038/jhg.2010.126. . Para grabar el vídeo, utilicé un adaptador de @ilabcam . . . #ojo #pupila #iris #vision #microscopio #divulgar ...

Mar 12, 2023 View →
Denji and Pochita in Chainsaw Man Fan Art | Drawing and Sketch ...
TikTok

doi: 10.1038/jhg.2010.126. . Para grabar el vídeo, utilicé un adaptador de @ilabcam . . . #ojo #pupila #iris #vision #microscopio #divulgar ...

Nov 2, 2022 View →
Consejos de Salud: Retirando Restos de Maquillaje en los Ojos ...
TikTok

doi: 10.1038/jhg.2010.126. . Para grabar el vídeo, utilicé un adaptador de @ilabcam . . . #ojo #pupila #iris #vision #microscopio #divulgar ...

Jul 26, 2022 View →
Imágenes Asombrosas bajo el Microscopio | TikTok
TikTok

doi: 10.1038/jhg.2010.126. . Para grabar el vídeo, utilicé un adaptador de @ilabcam . . . #ojo #pupila #iris #vision #microscopio #divulgar ...

May 29, 2022 View →
#ojo #ojohumano #maqueta #foryou | TikTok
TikTok

doi: 10.1038/jhg.2010.126. . Para grabar el vídeo, utilicé un adaptador de @ilabcam . . . #ojo #pupila #iris #vision #microscopio #divulgar ...

Mar 7, 2022 View →
Maqueta del Ojo Humano: Manualidades Creativas | TikTok
TikTok

doi: 10.1038/jhg.2010.126. . Para grabar el vídeo, utilicé un adaptador de @ilabcam . . . #ojo #pupila #iris #vision #microscopio #divulgar ...

Feb 5, 2022 View →
(Spoilers extended) Boleh ke orang IRL ada mata kelabu macam ...
Reddit

... and human eye color. J Hum Genet 56, 5–7 (2011). https://doi.org/10.1038/jhg.2010.126 · LordSuzano. • 4 thn lalu • Diedit 4 thn lalu.

Oct 29, 2021 View →
(Spoilereita laajennettu) Voiko ihmisillä IRL olla harmaat silmät ...
Reddit

... and human eye color. J Hum Genet 56, 5–7 (2011). https://doi.org/10.1038/jhg.2010.126 · LordSuzano. • 4 v sitten • Muokattiin 4 v sitten.

Oct 28, 2021 View →
(剧透警告)现实生活中,人们能有像史塔克家族那样的灰色眼睛吗 ...
Reddit

... M. 基因型-表型关联和人类眼睛颜色。J Hum Genet 56, 5–7 (2011)。 https://doi.org/10.1038/jhg.2010.126 · LordSuzano. • 4年前 • 4年前 编辑.

Oct 28, 2021 View →
(Спойлеры расширенные) Могут ли люди в реальной жизни ...
Reddit

... Smith, M. Genotype–phenotype associations and human eye color. J Hum Genet 56, 5–7 (2011). https://doi.org/10.1038/jhg.2010.126 · LordSuzano. • ...

Oct 28, 2021 View →
(Spoilers extended) Can people IRL have grey eyes like the Starks ...
Reddit

... phenotype associations and human eye color. J Hum Genet 56, 5–7 (2011). https://doi.org/10.1038/jhg.2010.126 · LordSuzano. • 4y ago • Edited 4y ...

Oct 28, 2021 View →
(Spoilers extended) Kan människor IRL ha grå ögon som Starks? : r ...
Reddit

... . Genotype–phenotype associations and human eye color. J Hum Genet 56, 5–7 (2011). https://doi.org/10.1038/jhg.2010.126 · LordSuzano. • för ...

Oct 28, 2021 View →
(劇透警告)現實生活中,人們可以有像史塔克家族那樣的灰色眼睛 ...
Reddit

... –phenotype associations and human eye color. J Hum Genet 56, 5–7 (2011). https://doi.org/10.1038/jhg.2010.126 · LordSuzano. • 4 年前 ...

Oct 28, 2021 View →
(스포일러 주의) 현실에서 스타크 가문 사람들처럼 회색 눈을 가진 사람 ...
Reddit

... –phenotype associations and human eye color. J Hum Genet 56, 5–7 (2011). https://doi.org/10.1038/jhg.2010.126 · LordSuzano. • 4년 전 ...

Oct 28, 2021 View →
(Spoilere utvidet) Kan folk IRL ha grå øyne som Stark-ene? : r/asoiaf
Reddit

... . Genotype–phenotype associations and human eye color. J Hum Genet 56, 5–7 (2011). https://doi.org/10.1038/jhg.2010.126 · LordSuzano. • for ...

Oct 28, 2021 View →
(Spoiler estesi) Le persone nella vita reale possono avere occhi ...
Reddit

... and human eye color. J Hum Genet 56, 5–7 (2011). https://doi.org/10.1038/jhg.2010.126 · LordSuzano. • 4 anni fa • Modificato 4 anni fa.

Oct 28, 2021 View →
OJO VISTO DESDE UN MICROSCOPIO #ojo #microscope #casos ...
TikTok

doi: 10.1038/jhg.2010.126. . Para grabar el vídeo, utilicé un adaptador de @ilabcam . . . #ojo #pupila #iris #vision #microscopio #divulgar ...

Feb 1, 2021 View →
What Are the Chances of Having Red Hair and Green Eyes?
News

https://doi.org/10.1038/jhg.2010.126. Share this article. Medically reviewed by Cynthia Taylor Chavoustie, MPAS, PA-C — Written by Kristeen ...

Jun 24, 2020 View →