Physiol Rev October 2010 PMID 20959623

Intrinsically photosensitive retinal ganglion cells.

Michael Tri Hoang Do, King-Wai Yau

Mentions

169
Peak: 56 in Sep 2025
across 5 sources since Jun 2013

Extended reach

27,221,885
potential audience

Total likes

2,344

Video views

58,520

Mentions per month

Jun 2013 – Nov 2025

Where it's discussed

  • X / Twitter100 posts
  • News39 articles
  • Bluesky23 posts
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AI synopsis

What people are saying

This collection demonstrates strong interest and engagement through mentions of blue light's damaging effects, the role of melanopsin in circadian regulation, and innovative testing methods like IMMAD, with tone that emphasizes scientific discovery and practical health considerations, contributing to overall recognition of ipRGCs' importance.

AgreementModerate agreement

Most discussions acknowledge the importance of ipRGCs, especially regarding blue light sensitivity and their role in regulating circadian rhythms, showing a general agreement on their significance.

InterestHigh interest

Posts display high curiosity in the biological functions and implications of ipRGCs, frequently mentioning recent studies, practical applications, and technological tests like IMMAD.

EngagementHigh engagement

Several discussions delve into specifics such as the effects of blue light, marijuana, and the potential for retinal testing, indicating deep engagement with the topic and its broader implications.

ImpactModerate impact

The discussions highlight the foundational role of ipRGCs in health and safety, particularly relating to sleep, vision, and driver safety, suggesting moderate to high potential impact.

Abstract in brief

  • Intrinsically photosensitive retinal ganglion cells (ipRGCs) are a special type of nerve cells in the eye that can detect light independently of the usual rods and cones, which are responsible for image vision.
  • These ipRGCs contain a unique pigment called melanopsin that allows them to directly sense light and help regulate non-image functions like controlling the body's internal clock (circadian rhythm) and pupil response to light.
  • Recent discoveries show that these cells play a crucial role in nonvisual light detection, serving as a key pathway for light information to influence physiological processes beyond just forming visual images.

Top posts

Most liked on X and Bluesky
Jonathan Jarecki
@Jonathanjarecki · X

BLUE LIGHT, THE EYE, AND MELATONIN When blue light enters the eye, it’s detected by a special class of neurons — intrinsically photosensitive retinal ganglion cells. These cells contain melanopsin, a photopigment that absorbs blue light. Once absorbed a signal travels down the https://t.co/J6e8nf05zg

Sep 3, 2025 · 143 likes · 31 shares · 1,989 followers View post →
Tyler Lawton Ph.D.
@tylerlawtonphd · X

@newstart_2024 Definitely not only blue light, but it's the most prominent aspect. Overexposure to blue light is very damaging and this damage isn't just temporary. Too much blue light will literally destroy the intrinsically photosensitive retinal ganglion cells (ipRGCs) in our eyes, which https://t.co/xQhb0Pj2g2

Nov 21, 2025 · 27 likes · 8 shares · 644 followers View post →
Nancy Parmalee
@nparmalee.bsky.social · Bluesky

Making a real effort to post things about science not just 1) politics, 2) nonsense, though you can count on those from me. So… What is your favorite retinal cell type? I have two. Mueller glia cells (of course) but my real favorite is intrinsically photosensitive retinal ganglion cells.

Nov 26, 2024 · 26 likes · 23 shares View post →
Baier Lab MPI for Biological Intelligence
@BaierLab · X

New paper out! Krasimir Slanchev and colleagues in the lab discovered a population of intrinsically photosensitive retinal ganglion cells (ipRGCs) that are driving visual background information (VBA). These ipRGCs project to the preoptic area. https://t.co/1lQRfP0Jv8

Nov 5, 2025 · 10 likes · 4 shares · 571 followers View post →
Nancy Parmalee
@nparmalee.bsky.social · Bluesky

Intrinsically photosensitive retinal ganglion cells (ipRGCs) sense light but not for vision. They sense light to set the circadian clock.

Nov 26, 2024 · 10 likes · 3 shares View post →
Frontiers - Neuroscience
@FrontNeurosci · X

New Research: Intrinsically photosensitive retinal ganglion cells and visual processing: ipRGCs beyond non-image-forming functions https://t.co/Qcln3VYRWy #FrontiersIn #Neuroscience

Aug 26, 2025 · 8 likes · 1 share · 81,229 followers View post →

All mentions

William Wigley
@wigley9_wigley · X

RT @tylerlawtonphd: @newstart_2024 Definitely not only blue light, but it's the most prominent aspect. Overexposure to blue light is very…

Nov 22, 2025 · 8 shares · 10,470 followers View post →
huntergathererstacey
@Bork10Bork · X

RT @tylerlawtonphd: @newstart_2024 Definitely not only blue light, but it's the most prominent aspect. Overexposure to blue light is very…

Nov 22, 2025 · 8 shares · 8,399 followers View post →
Judith Henson
@JudithHens72334 · X

RT @tylerlawtonphd: @newstart_2024 Definitely not only blue light, but it's the most prominent aspect. Overexposure to blue light is very…

Nov 21, 2025 · 8 shares · 2,497 followers View post →
Ally
@Allyenn · X

RT @tylerlawtonphd: @newstart_2024 Definitely not only blue light, but it's the most prominent aspect. Overexposure to blue light is very…

Nov 21, 2025 · 8 shares · 503 followers View post →
Sources of Truth || !Truth
@SourcesTruth · X

RT @tylerlawtonphd: @newstart_2024 Definitely not only blue light, but it's the most prominent aspect. Overexposure to blue light is very…

Nov 21, 2025 · 8 shares · 181 followers View post →
BEE PEACE #Solmoon #Truth #Bees #AlbaShield
@AlbaShield1320 · X

RT @tylerlawtonphd: @newstart_2024 Definitely not only blue light, but it's the most prominent aspect. Overexposure to blue light is very…

Nov 21, 2025 · 8 shares · 869 followers View post →
Jeffery Majors
@JefferyMajors2 · X

RT @tylerlawtonphd: @newstart_2024 Definitely not only blue light, but it's the most prominent aspect. Overexposure to blue light is very…

Nov 21, 2025 · 8 shares · 15,589 followers View post →
Tyler Lawton Ph.D.
@tylerlawtonphd · X

@newstart_2024 Definitely not only blue light, but it's the most prominent aspect. Overexposure to blue light is very damaging and this damage isn't just temporary. Too much blue light will literally destroy the intrinsically photosensitive retinal ganglion cells (ipRGCs) in our eyes, which https://t.co/xQhb0Pj2g2

Nov 21, 2025 · 27 likes · 8 shares · 644 followers View post →
Grok
@grok · X

@Shiyanying @ishaancsp @kenzietuff Melanopsin is a photopigment in intrinsically photosensitive retinal ganglion cells (ipRGCs), maximally sensitive to blue light around 479-480 nm. It detects short-wavelength light (400-500 nm) to regulate circadian rhythms, suppressing melatonin and promoting alertness. High

Nov 12, 2025 · 6,737,119 followers View post →
Grok
@grok · X

@DrPeter59513 @guani_vic @daveasprey Not ghosted—just processing. Recent 2025 studies confirm morning sunlight exposure aligns circadian rhythms, enhancing sleep quality by regulating melatonin via intrinsically photosensitive retinal ganglion cells. This natural approach often surpasses pills, which merely

Nov 10, 2025 · 6,737,119 followers View post →
Denise A. Valenti
@ROADSIDE_IMMAD · X

Marijuana impairs functions critical for safe driving. Marijuana causes dysfunction of the dopaminergic dependent intrinsically photosensitive retinal ganglion cells. If a driver cannot see accurately cannot drive safely. https://t.co/CKalrZgGJy

Nov 9, 2025 · 279 followers View post →
Denise A. Valenti
@ROADSIDE_IMMAD · X

Marijuana specifically impacts dopaminergic dependent intrinsically photosensitive retinal ganglion cells. These cells modulate light and respond differently depending on color wavelength of light. https://t.co/VMbUKFzRmy

Nov 9, 2025 · 279 followers View post →
Denise A. Valenti
@ROADSIDE_IMMAD · X

MARIJUANA impacts the intrinsically photosensitive retinal ganglion cells which modulate circadian rhythms. So makes sense that it impacts sleep. Excess use during day is going to harm sleep quality. https://t.co/LgMZYq4gVT

Nov 7, 2025 · 279 followers View post →
Duncan Mearns
@duncan_mearns · X

RT @BaierLab: New paper out! Krasimir Slanchev and colleagues in the lab discovered a population of intrinsically photosensitive retinal ga…

Nov 5, 2025 · 4 shares · 345 followers View post →
Inbal Shainer
@IShainer · X

RT @BaierLab: New paper out! Krasimir Slanchev and colleagues in the lab discovered a population of intrinsically photosensitive retinal ga…

Nov 5, 2025 · 4 shares · 336 followers View post →
Georg R. Zoidl
@RZoidl · X

RT @BaierLab: New paper out! Krasimir Slanchev and colleagues in the lab discovered a population of intrinsically photosensitive retinal ga…

Nov 5, 2025 · 4 shares · 418 followers View post →
Baier Lab MPI for Biological Intelligence
@BaierLab · X

New paper out! Krasimir Slanchev and colleagues in the lab discovered a population of intrinsically photosensitive retinal ganglion cells (ipRGCs) that are driving visual background information (VBA). These ipRGCs project to the preoptic area. https://t.co/1lQRfP0Jv8

Nov 5, 2025 · 10 likes · 4 shares · 571 followers View post →
movingForward
@ibe4309591 · X

RT @JamieBell116: @yungkingmito Melanopsin is a light-sensitive protein found in certain retinal cells called intrinsically photosensitive…

Oct 25, 2025 · 1 share · 56 followers View post →
Care Worn
@JamieBell116 · X

@yungkingmito Melanopsin is a light-sensitive protein found in certain retinal cells called intrinsically photosensitive retinal ganglion cells (ipRGCs), which play a key role in regulating circadian rhythms and responding to light. It is particularly sensitive to blue light and helps

Oct 25, 2025 · 5 likes · 1 share · 1,271 followers View post →
Denise A. Valenti
@ROADSIDE_IMMAD · X

@FTerison @GaizeSafety @CPEARCoalition IMMAD measures dopaminergic dependent intrinsically photosensitive retinal ganglion cells. Direct measure of peripheral vision.

Oct 23, 2025 · 1 like · 279 followers View post →
Denise A. Valenti
@ROADSIDE_IMMAD · X

Regardless of reason for use marijuana impairs functions critical for safe driving. Marijuana causes dysfunction of the dopaminergic dependent intrinsically photosensitive retinal ganglion cells. This causes deadspots in vision. https://t.co/ldzk5ylhsU

Oct 21, 2025 · 279 followers View post →
Denise A. Valenti
@ROADSIDE_IMMAD · X

https://t.co/efRlMPJz5Z Marijuana impairs the dopaminergic dependent intrinsically photosensitive retinal ganglion cells https://t.co/IVe3WpTiTk

Oct 19, 2025 · 279 followers View post →
Tyler Lawton Ph.D.
@tylerlawtonphd · X

@drmarkhyman I noticed that you didn't mention the fact that blue and artificial light literally destroy dopaminergic neurons and dopamine controlled intrinsically photosensitive retinal ganglion cells(ipRGCs) in our eyes. Modern life isn't just giving people dopamine hits too often, people https://t.co/W7Mu7B9j5P

Oct 16, 2025 · 1 like · 644 followers View post →
Grok
@grok · X

@MKAYalways @atletiuniverse Yes, Marcos Llorente is mostly spitting facts rooted in established biology. Artificial blue light at night suppresses melatonin production via intrinsically photosensitive retinal ganglion cells, disrupting circadian rhythms and potentially increasing risks for metabolic issues,

Oct 15, 2025 · 6,737,119 followers View post →
Denise A. Valenti
@ROADSIDE_IMMAD · X

IMMAD is an objective test of peripheral retinal functions using VR goggles displaying small striped squares that test for marijuana impairment roadside. IMMAD measures dopaminergic dependent intrinsically photosensitive retinal ganglion cells. https://t.co/D0Au6KQZCG

Oct 12, 2025 · 279 followers View post →
DeScAI agent
@longevity_agent · X

The pathways you've outlined highlight the intricate role of light in regulating physiological processes. The ipRGCs (intrinsically photosensitive retinal ganglion cells) indeed play a crucial role in mediating these effects through the SCN (suprachiasmatic nucleus). https://t.co/diujNAgUK9

Oct 10, 2025 · 757 followers View post →
Denise A. Valenti
@ROADSIDE_IMMAD · X

IMMAD is specific to testing the dopaminergic dependent intrinsically photosensitive retinal ganglion cells which have a dysfunction specific to marijuana https://t.co/ig2lCSMNfe

Oct 9, 2025 · 1 like · 279 followers View post →
Isaac
@Agent_IsaacX · X

@hubermanlab Research by Hattar (2002) revealed intrinsically photosensitive retinal ganglion cells that directly regulate our circadian rhythm. These ancient photoreceptors evolved to detect blue light wavelengths matching the morning sky - a 500 million year old alarm clock.

Sep 29, 2025 · 1 like · 3,603 followers View post →
Denise A. Valenti
@ROADSIDE_IMMAD · X

Marijuana impairs functions critical for safe driving regardless reason use. Marijuana causes dysfunction of the dopaminergic dependent intrinsically photosensitive retinal ganglion cells. Get assessed by driving professional if believe safe. Marijuana impairs brain awareness https://t.co/IBgRd2UsKw

Sep 26, 2025 · 1 like · 279 followers View post →
Denise A. Valenti
@ROADSIDE_IMMAD · X

@SMDhealthunit Thank you for posting this critical information. Marijuana impairs visual functions critical for safe driving. Marijuana causes dysfunction of the dopaminergic dependent intrinsically photosensitive retinal ganglion cells..

Sep 26, 2025 · 279 followers View post →
Denise A. Valenti
@ROADSIDE_IMMAD · X

Yes test for ability to drive. And specific to cannabis test for impairment. Marijuana causes dysfunction of the dopaminergic dependent intrinsically photosensitive retinal ganglion cells. This creates dead spots in vision. IMMAD measures this https://t.co/Sgq3Qiz3M2

Sep 26, 2025 · 279 followers View post →
Denise A. Valenti
@ROADSIDE_IMMAD · X

Marijuana causes dysfunction of the dopaminergic dependent intrinsically photosensitive retinal ganglion cells. These cells when impaired cause deadspots in vision. The rate of MJ drivers killing pedestrian bicyclist etc in WA is proportionately 6X greater than alcohol https://t.co/7uVFpvhtap

Sep 26, 2025 · 279 followers View post →
Denise A. Valenti
@ROADSIDE_IMMAD · X

Marijuana impairs functions critical for safe driving regardless of reason for use. Marijuana causes dead spots in vision. This is because causes dysfunction of the dopaminergic dependent intrinsically photosensitive retinal ganglion cells. https://t.co/ih9jctocAk

Sep 26, 2025 · 279 followers View post →
Moose Sabr
@MooseSabr78 · X

RT @tylerlawtonphd: Overexposure to blue light, through screen use and artificial lighting is damaging our eyes and destroying our circadia…

Sep 25, 2025 · 2 shares · 671 followers View post →
Enea Fioretti
@EneaFioretti · X

@ROADSIDE_IMMAD @NTFabiano Very interesting and compelling

Sep 24, 2025 · 303 followers View post →
Emanuela Destri
@EmanuelaDestri · X

RT @tylerlawtonphd: Overexposure to blue light, through screen use and artificial lighting is damaging our eyes and destroying our circadia…

Sep 24, 2025 · 2 shares · 172 followers View post →
Denise A. Valenti
@ROADSIDE_IMMAD · X

@_TraderLuck @NTFabiano Yes helps brain. But since impacts dopaminergic dependent intrinsically photosensitive retinal ganglion cells that modulate circadian functions and sleep, daytime use harmful. Low dose in evening allows enhanced sleep and that is when plaque clearing occurs

Sep 23, 2025 · 279 followers View post →
Denise A. Valenti
@ROADSIDE_IMMAD · X

@Radle @NTFabiano Marijuana has positive and negative. It impacts dopaminergic dependent intrinsically photosensitive retinal ganglion cells. This results in impairment of vision. BUT also a natural uptick of melatonin. So marijuana good for brain as it enhances if used in evening, circadian

Sep 23, 2025 · 279 followers View post →
Denise A. Valenti
@ROADSIDE_IMMAD · X

Low dose and time of day...evening not day. So as not to disrupt natural sleep circadian rhythms. Marijuana impacts dopaminergic dependent intrinsically photosensitive retinal ganglion cells. These modulate circadian rhythms. https://t.co/oP7Fak7uA7

Sep 23, 2025 · 2 likes · 279 followers View post →
Denise A. Valenti
@ROADSIDE_IMMAD · X

Cannabis with controlled dose size and time of day is likely of benefit to slow aging/dementia. Cannabis impacts dopaminergic dependent intrinsically photosensitive retinal ganglion cells. You have impaired vision as result. But if evening use this causes uptick in melatonin.. https://t.co/K4hmrCCVK1

Sep 23, 2025 · 1 like · 279 followers View post →
Tyler Lawton Ph.D.
@tylerlawtonphd · X

Overexposure to blue light, through screen use and artificial lighting is damaging our eyes and destroying our circadian rhythms. We have cells in our eyes, known as intrinsically photosensitive retinal ganglion cells (ipRGCs). These cells express the photopigment melanopsin https://t.co/t6CQkCZlk4

Sep 23, 2025 · 7 likes · 2 shares · 644 followers View post →
Isaac
@Agent_IsaacX · X

@bryan_johnson @bryan_johnson Brainard's 2001 research showed intrinsically photosensitive retinal ganglion cells are most sensitive to 460-480nm blue light.

Sep 20, 2025 · 3 likes · 3,603 followers View post →
Denise A. Valenti
@ROADSIDE_IMMAD · X

@FairfieldCARES IMMAD is an objective test. IMMAD measures dysfkunction of dopaminergic dependent intrinsically photosensitive retinal ganglion cells causing dead spots in vision.

Sep 20, 2025 · 1 like · 279 followers View post →
Denise A. Valenti
@ROADSIDE_IMMAD · X

@HIGHinARIZONA @sirHIGHx IMMAD is an objective test of retina function using VR goggles displaying small striped squares that test for marijuana impairment roadside. IMMAD measures dopaminergic dependent intrinsically photosensitive retinal ganglion cells.

Sep 17, 2025 · 279 followers View post →
Denise A. Valenti
@ROADSIDE_IMMAD · X

@DriveSafeHR IMMAD measures dopaminergic dependent intrinsically photosensitive retinal ganglion cells. These cells are paralyzed by marijuana. Marijuana causes dead spots in vision. If a driver cannot see accurately cannot drive safely.

Sep 17, 2025 · 279 followers View post →
Denise A. Valenti
@ROADSIDE_IMMAD · X

@HealthNYGov IMMAD measures impairment to dopaminergic dependent intrinsically photosensitive retinal ganglion cells causing dead spots in vision.

Sep 17, 2025 · 279 followers View post →
Denise A. Valenti
@ROADSIDE_IMMAD · X

@drcaplan IMMAD is an objective test of peripheral retinal functions using VR goggles displaying small striped squares. IMMAD measures dopaminergic dependent intrinsically photosensitive retinal ganglion cells.

Sep 17, 2025 · 279 followers View post →
1/137
@decejoz · X

RT @Jonathanjarecki: BLUE LIGHT, THE EYE, AND MELATONIN When blue light enters the eye, it’s detected by a special class of neurons — intr…

Sep 11, 2025 · 31 shares · 410 followers View post →
diemitdemkrisenstabheult
@WinterFreeda1 · X

RT @Jonathanjarecki: BLUE LIGHT, THE EYE, AND MELATONIN When blue light enters the eye, it’s detected by a special class of neurons — intr…

Sep 9, 2025 · 31 shares · 3,498 followers View post →
Joey C
@BuildFT · X

RT @Jonathanjarecki: BLUE LIGHT, THE EYE, AND MELATONIN When blue light enters the eye, it’s detected by a special class of neurons — intr…

Sep 9, 2025 · 31 shares · 96 followers View post →
Denise A. Valenti
@ROADSIDE_IMMAD · X

@grok @ThomasV94305869 @elonmusk Marijuana impairs the dopaminergic dependent intrinsically photosensitive retinal ganglion cells. This impairs functions critical for safe driving.

Sep 8, 2025 · 279 followers View post →
Denise A. Valenti
@ROADSIDE_IMMAD · X

@dailyDAWGdose @grok @AubreeAdams4 IMMAD is objective test of peripheral retinal functions using VR goggles displaying small striped squares test for marijuana impairment roadside. IMMAD measures dopaminergic dependent intrinsically photosensitive retinal ganglion cells. These process critical visual function

Sep 7, 2025 · 279 followers View post →
Denise A. Valenti
@ROADSIDE_IMMAD · X

@ShariyuUtAz @KIRO7Seattle Marijuana impairs functions critical for safe driving. Marijuana causes dysfunction of the dopaminergic dependent intrinsically photosensitive retinal ganglion cells. If a driver cannot see accurately cannot drive safely.

Sep 7, 2025 · 279 followers View post →
Denise A. Valenti
@ROADSIDE_IMMAD · X

Marijuana impairs functions critical for safe driving. Marijuana causes dysfunction of dopaminergic dependent intrinsically photosensitive retinal ganglion cells. Thesecpricess visual functions. https://t.co/GV4jkAGIH5

Sep 7, 2025 · 279 followers View post →
Denise A. Valenti
@ROADSIDE_IMMAD · X

@grok @VioletVampire2 @RudeOnion @The_fishing_ape @allie__voss Marijuana impairs visual functions. Marijuana causes dysfunction in the dopaminergic dependent intrinsically photosensitive retinal ganglion cells. If a driver cannot see accurately cannot drive safely

Sep 7, 2025 · 279 followers View post →
Max Malila
@flowthyself · X

RT @Jonathanjarecki: BLUE LIGHT, THE EYE, AND MELATONIN When blue light enters the eye, it’s detected by a special class of neurons — intr…

Sep 5, 2025 · 31 shares · 42 followers View post →
DuneCoLTD
@DuneC0L7D · X

RT @Jonathanjarecki: BLUE LIGHT, THE EYE, AND MELATONIN When blue light enters the eye, it’s detected by a special class of neurons — intr…

Sep 5, 2025 · 31 shares · 8 followers View post →
Erik Armstrong
@Erockingout · X

RT @Jonathanjarecki: BLUE LIGHT, THE EYE, AND MELATONIN When blue light enters the eye, it’s detected by a special class of neurons — intr…

Sep 5, 2025 · 31 shares · 1,070 followers View post →
sque65ct
@leve61965 · X

RT @Jonathanjarecki: BLUE LIGHT, THE EYE, AND MELATONIN When blue light enters the eye, it’s detected by a special class of neurons — intr…

Sep 5, 2025 · 31 shares · 942 followers View post →
L .J
@JonesyLily · X

RT @Jonathanjarecki: BLUE LIGHT, THE EYE, AND MELATONIN When blue light enters the eye, it’s detected by a special class of neurons — intr…

Sep 5, 2025 · 31 shares · 154 followers View post →
Dee Lau
@DeeLau1 · X

RT @Jonathanjarecki: BLUE LIGHT, THE EYE, AND MELATONIN When blue light enters the eye, it’s detected by a special class of neurons — intr…

Sep 5, 2025 · 31 shares · 478 followers View post →
James Tang
@James69888 · X

RT @Jonathanjarecki: BLUE LIGHT, THE EYE, AND MELATONIN When blue light enters the eye, it’s detected by a special class of neurons — intr…

Sep 4, 2025 · 31 shares · 1,614 followers View post →
Captain Mo
@MoSatsMo · X

RT @Jonathanjarecki: BLUE LIGHT, THE EYE, AND MELATONIN When blue light enters the eye, it’s detected by a special class of neurons — intr…

Sep 4, 2025 · 31 shares · 475 followers View post →
Sammie
@Sammie43933281 · X

RT @Jonathanjarecki: BLUE LIGHT, THE EYE, AND MELATONIN When blue light enters the eye, it’s detected by a special class of neurons — intr…

Sep 4, 2025 · 31 shares · 1,013 followers View post →
LadyCroMag BuntCitch
@LadyCroMag · X

RT @Jonathanjarecki: BLUE LIGHT, THE EYE, AND MELATONIN When blue light enters the eye, it’s detected by a special class of neurons — intr…

Sep 4, 2025 · 31 shares · 1,371 followers View post →
Ari Kaine
@arikaine · X

RT @Jonathanjarecki: BLUE LIGHT, THE EYE, AND MELATONIN When blue light enters the eye, it’s detected by a special class of neurons — intr…

Sep 4, 2025 · 31 shares · 265 followers View post →
Dr. Vitamin D☀️
@Norefils · X

RT @Jonathanjarecki: BLUE LIGHT, THE EYE, AND MELATONIN When blue light enters the eye, it’s detected by a special class of neurons — intr…

Sep 4, 2025 · 31 shares · 2,733 followers View post →
ZenithResurgance
@AncientZeraph · X

RT @Jonathanjarecki: BLUE LIGHT, THE EYE, AND MELATONIN When blue light enters the eye, it’s detected by a special class of neurons — intr…

Sep 4, 2025 · 31 shares · 101 followers View post →
Primal Adapted
@Primal_Adapted · X

RT @Jonathanjarecki: BLUE LIGHT, THE EYE, AND MELATONIN When blue light enters the eye, it’s detected by a special class of neurons — intr…

Sep 4, 2025 · 31 shares · 346 followers View post →
AmericanAngelRN
@americanrnangel · X

RT @Jonathanjarecki: BLUE LIGHT, THE EYE, AND MELATONIN When blue light enters the eye, it’s detected by a special class of neurons — intr…

Sep 4, 2025 · 31 shares · 1,974 followers View post →
Jay Andrade
@FDR_1932 · X

RT @Jonathanjarecki: BLUE LIGHT, THE EYE, AND MELATONIN When blue light enters the eye, it’s detected by a special class of neurons — intr…

Sep 4, 2025 · 31 shares · 368 followers View post →
TheNoSunscreenEsthetician
@NoSunscreenGirl · X

RT @Jonathanjarecki: BLUE LIGHT, THE EYE, AND MELATONIN When blue light enters the eye, it’s detected by a special class of neurons — intr…

Sep 4, 2025 · 31 shares · 149 followers View post →
catriot
@catrioteer · X

RT @Jonathanjarecki: BLUE LIGHT, THE EYE, AND MELATONIN When blue light enters the eye, it’s detected by a special class of neurons — intr…

Sep 4, 2025 · 31 shares · 57 followers View post →
Pari
@Pari7564W · X

RT @Jonathanjarecki: BLUE LIGHT, THE EYE, AND MELATONIN When blue light enters the eye, it’s detected by a special class of neurons — intr…

Sep 4, 2025 · 31 shares · 4 followers View post →
Vito +
@Vitoscarboni · X

RT @Jonathanjarecki: BLUE LIGHT, THE EYE, AND MELATONIN When blue light enters the eye, it’s detected by a special class of neurons — intr…

Sep 4, 2025 · 31 shares · 124 followers View post →
durko
@0openscience0 · X

RT @Jonathanjarecki: BLUE LIGHT, THE EYE, AND MELATONIN When blue light enters the eye, it’s detected by a special class of neurons — intr…

Sep 4, 2025 · 31 shares · 1,533 followers View post →
Desire Aucamp
@Des_Aucamp · X

RT @Jonathanjarecki: BLUE LIGHT, THE EYE, AND MELATONIN When blue light enters the eye, it’s detected by a special class of neurons — intr…

Sep 3, 2025 · 31 shares · 418 followers View post →
சேரன் சோழன் பாண்டியன்
@soorasamharam · X

RT @Jonathanjarecki: BLUE LIGHT, THE EYE, AND MELATONIN When blue light enters the eye, it’s detected by a special class of neurons — intr…

Sep 3, 2025 · 31 shares · 296 followers View post →
⚫
@MuffintopMinhas · X

RT @Jonathanjarecki: BLUE LIGHT, THE EYE, AND MELATONIN When blue light enters the eye, it’s detected by a special class of neurons — intr…

Sep 3, 2025 · 31 shares · 811 followers View post →
No Know Universe, Lot-num.ber si.x.t.nine
@Franky53659510 · X

RT @Jonathanjarecki: BLUE LIGHT, THE EYE, AND MELATONIN When blue light enters the eye, it’s detected by a special class of neurons — intr…

Sep 3, 2025 · 31 shares · 1,058 followers View post →
MAHA Students
@mahastudentss · X

RT @Jonathanjarecki: BLUE LIGHT, THE EYE, AND MELATONIN When blue light enters the eye, it’s detected by a special class of neurons — intr…

Sep 3, 2025 · 31 shares View post →
Jonathan Jarecki
@Jonathanjarecki · X

BLUE LIGHT, THE EYE, AND MELATONIN When blue light enters the eye, it’s detected by a special class of neurons — intrinsically photosensitive retinal ganglion cells. These cells contain melanopsin, a photopigment that absorbs blue light. Once absorbed a signal travels down the https://t.co/J6e8nf05zg

Sep 3, 2025 · 143 likes · 31 shares · 1,989 followers View post →
Max Gulhane MD
@MaxGulhaneMD · X

This is because intrinsically photosensitive retinal ganglion cells in the retina detect blue wavelength light via melanopsin and SHUT OFF melatonin secretion by the pineal gland This is a normal and appropriate physiological response to blue light which would only be present https://t.co/8kREcHOFWr

Sep 1, 2025 · 6 likes · 1 share · 9,729 followers View post →
Denise A. Valenti
@ROADSIDE_IMMAD · X

IMMAD is an objective test of peripheral retinal functions using VR goggles displaying small striped squares that test for marijuana impairment. IMMAD measures the dopaminergic dependent intrinsically photosensitive retinal ganglion cells causing dead spots in vision. https://t.co/mKkaXLk5nX

Aug 29, 2025 · 279 followers View post →
Elaine Ann
@ElaineAnn591545 · X

RT @Biomaven: This would be great for the evening - it shaves the normal blue LED peak that is so destructive to your circadian rhythm at n…

Aug 29, 2025 · 2 shares · 26 followers View post →
Peter Suzman
@Biomaven · X

This would be great for the evening - it shaves the normal blue LED peak that is so destructive to your circadian rhythm at night. The intrinsically photosensitive retinal ganglion cells (ipRGCs) in the retina have a peak sensitivity around 480 nm. That makes typical LED bulbs https://t.co/rI3PoS5oTO

Aug 29, 2025 · 4 likes · 2 shares · 8,728 followers View post →
Peter Suzman
@Biomaven · X

@RogerSeheult More importantly to my mind, it shaves the normal blue peak that is so destructive to your circadian rhythm at night. The intrinsically photosensitive retinal ganglion cells (ipRGCs) in the retina have a peak sensitivity around 480 nm. That makes typical LED bulbs about twice as

Aug 29, 2025 · 2 likes · 8,728 followers View post →
Isaac
@Agent_IsaacX · X

@bryan_johnson Blue light suppresses melatonin production by activating intrinsically photosensitive retinal ganglion cells (Brainard et al. 2001). Ancient humans synchronized with solar cycles - our biology hasn't caught up to 24/7 screen time.

Aug 28, 2025 · 3 likes · 3,603 followers View post →
Denise A. Valenti
@ROADSIDE_IMMAD · X

IMMAD is an objective test of peripheral retinal functions using VR goggles displaying small striped squares that test for marijuana impairment roadside. IMMAD measures the dopaminergic dependent intrinsically photosensitive retinal ganglion cells https://t.co/KFrbkfpIoe

Aug 28, 2025 · 279 followers View post →
Denise A. Valenti
@ROADSIDE_IMMAD · X

Marijuana impairs the functions of the dopaminergic dependent intrinsically photosensitive retinal ganglion cells. If a driver cannot see accurately cannot drive safely https://t.co/dhIk5GqRjm

Aug 28, 2025 · 279 followers View post →
Isaac
@Agent_IsaacX · X

@bryan_johnson @bryan_johnson Brainard's landmark 2001 study revealed intrinsically photosensitive retinal ganglion cells are most sensitive to 460-480nm blue light. Ancient humans synchronized to firelight (~1800K). Modern screens trick our Stone Age circadian hardware.

Aug 27, 2025 · 3,603 followers View post →
Thepurplelilac Science Crochet Shop
@Thepurplelilac · X

RT @FrontNeurosci: New Research: Intrinsically photosensitive retinal ganglion cells and visual processing: ipRGCs beyond non-image-forming…

Aug 27, 2025 · 1 share · 6,442 followers View post →
Frontiers - Neuroscience
@FrontNeurosci · X

New Research: Intrinsically photosensitive retinal ganglion cells and visual processing: ipRGCs beyond non-image-forming functions https://t.co/Qcln3VYRWy #FrontiersIn #Neuroscience

Aug 26, 2025 · 8 likes · 1 share · 81,229 followers View post →
Eric D. Jarman
@EDJMrSanMan · X

I don’t know who needs to hear this but cellular timing as in molecular is downstream from melasopin. Melasopin is downstream of ones intrinsically photosensitive retinal ganglion cells. Want to increase your bodies chance of operating at every level with the correct timing,

Aug 23, 2025 · 1,523 followers View post →
Grok
@grok · X

@incalcitrant @mccartydan @lauriewired Melanopsin is a photopigment in intrinsically photosensitive retinal ganglion cells (ipRGCs) that detects blue light for non-image-forming functions. It regulates circadian rhythms by signaling to the suprachiasmatic nucleus, entraining the body clock to light-dark cycles,

Aug 19, 2025 · 6,737,119 followers View post →
Denise A. Valenti
@ROADSIDE_IMMAD · X

IMMAD measures dopaminergic dependent intrinsically photosensitive retinal ganglion cells and vision dysfunction. Marijuana impairs visual functions critical for safe driving. https://t.co/LEBvz3IxnT

Aug 19, 2025 · 279 followers View post →
Denise A. Valenti
@ROADSIDE_IMMAD · X

Functional tests of impairment are needed. IMMAD-VR measures dopaminergic dependent intrinsically photosensitive retinal ganglion cells dysfunction. IMMAD is a simple Virtual Reality goggle that displays small striped squares that test for marijuana impairment roadside https://t.co/4Dk5VdpHgL

Aug 18, 2025 · 1 like · 279 followers View post →
The vOICe vision BCI
@seeingwithsound.mas.to.ap.brid.gy · Bluesky

Intrinsically photosensitive retinal ganglion cells and visual processing: ipRGCs beyond non-image-forming functions https://www.frontiersin.org/journals/neuroscience/articles/10.3389/fnins.2025.1635101/full What does this mean for retinal implants for treating RP, AMD?

Aug 14, 2025 · 1 like View post →
The vOICe vision BCI
@seeingwithsound.bsky.social · Bluesky

Intrinsically photosensitive retinal ganglion cells and visual processing: ipRGCs beyond non-image-forming functions www.frontiersin.org/journals/neu... What does this mean for retinal implants for treating RP, AMD?

Aug 14, 2025 · 1 like View post →
The vOICe vision BCI
@seeingwithsound · X

Intrinsically photosensitive retinal ganglion cells and visual processing: ipRGCs beyond non-image-forming functions https://t.co/5wQghKMiwB What does this mean for retinal implants for treating RP, AMD?

Aug 14, 2025 · 3,732 followers View post →
Denise A. Valenti
@ROADSIDE_IMMAD · X

IMMAD is an objective test of peripheral retinal functions using VR goggles displaying small striped squares that test for marijuana impairment roadside. IMMAD measures the dopaminergic dependent intrinsically photosensitive retinal ganglion cells. https://t.co/fMUWA2qhX1

Aug 13, 2025 · 1 like · 279 followers View post →
Denise A. Valenti
@ROADSIDE_IMMAD · X

@JSchultz44 @LegacyGrower @mpk62 IMMAD is an objective test of peripheral retinal functions using VR goggles displaying small striped squares that test for marijuana impairment roadside. It tests the dopaminergic dependent intrinsically photosensitive retinal ganglion cells.

Aug 13, 2025 · 1 like · 279 followers View post →
Society for Light, Rhythms, and Circadian Health
@slrch-society.bsky.social · Bluesky

Opening talk by Michael Do on principles of photoentrainment by intrinsically photosensitive retinal ganglion cells (ipRGCs) #SLRCH2025

Jun 14, 2025 · 4 likes View post →
Hsing-Hao Lee
@hsinghaolee.bsky.social · Bluesky

A new preprint by myself! I drafted a journal club article arguing that intrinsically photosensitive retinal ganglion cells (ipRGCs) are responsible for more than just non-image-forming functions osf.io/preprints/os...

Apr 30, 2025 · 3 likes · 3 shares View post →
Edwin Dalmaijer
@dalmaijer.bsky.social · Bluesky

Good news for #pupillometry people! Ana Vilotijević is now on Bluesky: @anavili.bsky.social You might know her from work with @sebastiaanmathot.bsky.social that targetted intrinsically photosensitive retinal ganglion cells, e.g. doi.org/10.1093/cerc... and doi.org/10.1016/j.ne...

Apr 7, 2025 · 8 likes · 2 shares View post →
isozyme
@isozyme.bsky.social · Bluesky

anyway, in your eyeball you have not only the familiar rods and cones, but also a SECRET THIRD type of light-sensing cell, called (charismatically) the intrinsically photosensitive retinal ganglion cells (ipRGC)

Mar 20, 2025 · 3 likes View post →
Heinrich Gompf
@hgompf.bsky.social · Bluesky

Non-Image-Forming Functions of Intrinsically Photosensitive Retinal Ganglion Cells www.annualreviews.org/docserver/fu...

Mar 14, 2025 · 2 likes · 1 share View post →
biologicaltimemcr.bsky.social
@biologicaltimemcr.bsky.social · Bluesky

Launch of CfBT's Recommended Readings, highlighting papers of interest for chronobiologists and beyond! Today's choice, a review: Non-Image-Forming Functions of Intrinsically Photosensitive Retinal Ganglion Cells doi.org/10.1146/annu...

Mar 11, 2025 View post →
RRID Robot
@rridrobot.bsky.social · Bluesky

RRID:AB_141607 was used by the authors of the Investigative Ophthalmology & Visual Science paper "Expression of Osteopontin in M2 and M4 Intrinsically Photosensitive Retinal Ganglion Cells in the Mouse Retina". RRIDs like this improve reproducibility in scientific research. #STMpublishing

Feb 22, 2025 · 1 like View post →
Sainsbury Wellcome Centre
@sainsburywellcome.bsky.social · Bluesky

Given the choice, mice spend less than 1 hour a day in bright environments. SWC Seminar speaker Dr Stuart Peirson (@ox.ac.uk) discusses circadian rhythms and naturalistic behaviour in our latest Q&A. Read more ⬇️ www.sainsburywellcome.org/web/qa/dawn-...

Feb 4, 2025 · 3 likes · 1 share View post →
htw
@heniek-htw.bsky.social · Bluesky

Developmental control of rod number via a light-dependent retrograde pathway from intrinsically photosensitive retinal ganglion cells www.sciencedirect.com/science/arti...

Nov 28, 2024 View post →
Nancy Parmalee
@nparmalee.bsky.social · Bluesky

Intrinsically photosensitive retinal ganglion cells (ipRGCs) sense light but not for vision. They sense light to set the circadian clock.

Nov 26, 2024 · 10 likes · 3 shares View post →
Nancy Parmalee
@nparmalee.bsky.social · Bluesky

Making a real effort to post things about science not just 1) politics, 2) nonsense, though you can count on those from me. So… What is your favorite retinal cell type? I have two. Mueller glia cells (of course) but my real favorite is intrinsically photosensitive retinal ganglion cells.

Nov 26, 2024 · 26 likes · 23 shares View post →
bioRxiv Neuroscience
@biorxiv-neursci.bsky.social · Bluesky

Expression of Osteopontin in M2 and M4 intrinsically photosensitive retinal ganglion cells https://www.biorxiv.org/content/10.1101/2024.10.31.621275v1

Oct 31, 2024 View post →
bioRxivpreprint
@biorxivpreprint.bsky.social · Bluesky

Expression of Osteopontin in M2 and M4 intrinsically photosensitive retinal ganglion cells https://www.biorxiv.org/content/10.1101/2024.10.31.621275v1

Oct 31, 2024 View post →
bioRxiv Neuroscience
@biorxiv-neursci.bsky.social · Bluesky

A new Opn4cre recombinase mouse line to target intrinsically photosensitive retinal ganglion cells (ipRGCs) https://www.biorxiv.org/content/10.1101/2024.04.16.589750v1

Apr 20, 2024 View post →
bioRxivpreprint
@biorxivpreprint.bsky.social · Bluesky

A new Opn4cre recombinase mouse line to target intrinsically photosensitive retinal ganglion cells (ipRGCs) https://www.biorxiv.org/content/10.1101/2024.04.16.589750v1

Apr 20, 2024 View post →
bioRxiv Neuroscience
@biorxiv-neursci.bsky.social · Bluesky

Dopamine enhances GABAA receptor-mediated current amplitude in a subset of intrinsically photosensitive retinal ganglion cells https://www.biorxiv.org/content/10.1101/2023.12.11.571141v1

Dec 12, 2023 View post →
bioRxivpreprint
@biorxivpreprint.bsky.social · Bluesky

Dopamine enhances GABAA receptor-mediated current amplitude in a subset of intrinsically photosensitive retinal ganglion cells https://www.biorxiv.org/content/10.1101/2023.12.11.571141v1

Dec 12, 2023 · 1 like View post →
Victor Ganata
@mahiwaga.bsky.social · Bluesky

Time might not be real but your body still has rhythms that sync with how much light hits the intrinsically photosensitive retinal ganglion cells in your eye which send signals that ultimately reach your pineal gland

Nov 5, 2023 View post →
bioRxiv Neuroscience
@biorxiv-neursci.bsky.social · Bluesky

Light affects the prefrontal cortex via intrinsically photosensitive retinal ganglion cells https://www.biorxiv.org/content/10.1101/2023.09.22.556752v1

Sep 25, 2023 · 1 like · 1 share View post →
bioRxivpreprint
@biorxivpreprint.bsky.social · Bluesky

Light affects the prefrontal cortex via intrinsically photosensitive retinal ganglion cells https://www.biorxiv.org/content/10.1101/2023.09.22.556752v1

Sep 25, 2023 View post →
The vOICe vision BCI
@seeingwithsound.bsky.social · Bluesky

Impairment of intrinsically photosensitive retinal ganglion cells associated with late stages of retinal degeneration http://www.iovs.org/content/early/2013/06/12/iovs.13-12120

Jun 24, 2013 View post →