February 2011 PMID 21233849

Evolution of multisubunit RNA polymerases in the three domains of life.

Finn Werner, Dina Grohmann

Mentions

3
Peak: 2 in Aug 2025
across 2 sources since Jun 2022

Extended reach

685
potential audience

Total likes

9

Video views

335

Mentions per month

Jun 2022 – Aug 2025

Where it's discussed

  • YouTube2 videos
  • X / Twitter1 posts

AI synopsis

What people are saying

The discussions demonstrate a shared understanding that archaeal RNA polymerases resemble eukaryotic ones, supported by references to homologous subunits and detailed research, with tone that reflects agreement and appreciation for scientific detail.

AgreementStrong agreement

The discussion strongly agrees with the idea that eukaryotes evolved from an archaeal ancestor, as evidenced by the acknowledgment of structural similarities and homologous subunits.

InterestModerate interest

Participants show moderate interest by referencing details like homologous subunits and specific research, indicating engagement but not extensive debate.

EngagementModerate engagement

The mention of a specific DOI and the brief elaboration on structural similarities suggest some depth of engagement, though it remains relatively straightforward.

ImpactModerate impact

The comments reinforce a consensus about evolutionary relationships, which could influence ongoing research and understanding, reflecting a slight but meaningful impact.

Abstract in brief

  • RNA polymerases (RNAPs) are essential for transcription in all living organisms, showcasing similarities in structure and function despite the diversity of organisms, from bacteria to humans.
  • Recent research has advanced our understanding of RNAPs' molecular composition and mechanism, shedding light on their evolution and how factors interact during transcription.
  • The paper discusses the evolutionary conservation and distinctions of RNAPs across the three domains of life and presents the 'elongation first' hypothesis regarding the evolution of transcriptional regulation.

Top posts

Most liked on X and Bluesky
Mathias Girbig
@MathiasGirbig · X

@tony_burnetti @LugerLab @macroliter @halvorz @MercerLab @HiCryoEM I guess we can agree that eukaryotes evolved from an archaeal host. Archaeal RNA polymerases are quite similar to eukaryotic ones. The 12 core subunits of euk Pols all are homologous to arch. Pol subunits, which is nicely described in DOI: 10.1038/nrmicro2507 (2/n)

Jun 6, 2022 · 1 like · 351 followers View post →

All mentions

Mathias Girbig
@MathiasGirbig · X

@tony_burnetti @LugerLab @macroliter @halvorz @MercerLab @HiCryoEM I guess we can agree that eukaryotes evolved from an archaeal host. Archaeal RNA polymerases are quite similar to eukaryotic ones. The 12 core subunits of euk Pols all are homologous to arch. Pol subunits, which is nicely described in DOI: 10.1038/nrmicro2507 (2/n)

Jun 6, 2022 · 1 like · 351 followers View post →