March 2011 PMID 21309657

Apixaban in patients with atrial fibrillation.

Stuart J Connolly, John Eikelboom, Campbell Joyner, Hans-Christoph Diener, Robert Hart, Sergey Golitsyn, Greg Flaker, Alvaro Avezum, Stefan H Hohnloser, Rafael Diaz, Mario Talajic, Jun Zhu, Prem Pais, Andrzej Budaj, Alexander Parkhomenko

Mentions

123
Peak: 30 in Jan 2025
across 5 sources since Jun 2019

Extended reach

2,642,616
potential audience

Total likes

583

Video views

19,649

Mentions per month

Jun 2019 – Oct 2025

Where it's discussed

  • X / Twitter105 posts
  • News10 articles
  • Facebook3 posts
  • Blogs3 articles
  • YouTube2 videos

AI synopsis

What people are saying

The collective discussions show strong support for apixaban's efficacy and safety, citing notable trials like AVERROES with phrases such as 'less effective at preventing stroke' and 'bleeding risk is comparable,' which highlight detailed analysis and cautious evaluation of data. The tone and word choice reflect thoughtful engagement with clinical evidence, emphasizing both the consistency and limitations of current research.

AgreementModerate agreement

Most discussions reference the AVERROES trial and support the effectiveness of apixaban, showing general agreement with the publication's findings.

InterestModerate interest

There is moderate curiosity about new anticoagulants, their safety, and comparison data, indicating steady-level interest.

EngagementHigh engagement

Many participants delve into detailed interpretations of trials like AVERROES and BAFTA, with some sharing clinical insights, demonstrating high engagement.

ImpactModerate impact

While the discussions are thorough, they mainly reinforce existing evidence and clinical practices, implying a moderate but meaningful impact.

Abstract in brief

  • Apixaban significantly reduced the occurrence of stroke and systemic embolism compared to aspirin in patients with atrial fibrillation who were unsuitable for vitamin K antagonists, with a hazard ratio of 0.45.
  • The study was stopped early due to the clear benefits seen with apixaban, which included lower rates of hospitalization for cardiovascular causes compared to aspirin (12.6% vs. 15.9% per year).
  • Both treatment groups had similar rates of major bleeding, indicating that apixaban is a safer option without a significant increase in bleeding risk.

Top posts

Most liked on X and Bluesky
NEJM
@NEJM · X

Original Article: Asundexian versus Apixaban in Patients with Atrial Fibrillation https://t.co/dZPaihNNp6 #Cardiology https://t.co/sx5FtVvSk5

Jan 1, 2025 · 102 likes · 21 shares · 931,827 followers View post →
European Society of Cardiology Journals
@ESC_Journals · X

Simultaneous publication during #ESCCongress Effectiveness and safety of Rivaroxaban versus Apixaban in patients with Atrial Fibrillation and Peripheral Artery Disease - https://t.co/HcLJEZcF8s #EHJPharmacotherapy https://t.co/BCyd7vmjNF

Aug 30, 2025 · 58 likes · 20 shares · 116,557 followers View post →
Ahmed Bennis MD
@drbennisahmed · X

Asundexian or Apixaban in Patients With Atrial Fibrillation According to Prior Oral Anticoagulant Use OCEANIC-AF Randomized Clinical Trial OAC-naive patients had a significantly smaller increase in stroke or systemic embolism with asundexian https://t.co/55ftteOfim https://t.co/L8xkzlVhmC

Jun 12, 2025 · 12 likes · 1 share · 3,192 followers View post →
Anesthesiology Journals
@_Anesthesiology · X

Direct-acting oral anticoagulants prevent stroke in patients with atrial fibrillation but carry the risk of bleeding. Read a summary of "Asundexian versus apixaban in patients with atrial fibrillation" in the May 2025 SM&A: https://t.co/gy6chMvLvn https://t.co/ifXTnOk1d5

May 12, 2025 · 11 likes · 1 share · 38,359 followers View post →
Musa A. Sharkawi
@MusaSharkawi · X

@willsuh76 Based on the AVERROES trial, I’d go with full dose Apixiban (unless pt has 2/3 of Cr >1.5, age >80 or weight<60 kg then 2.5 mg BID). In AVERROES, aspirin and apixiban had the same rate of bleeding. https://t.co/lHT35p62Dy

Oct 2, 2019 · 11 likes · 3,312 followers View post →
Ahmed Bennis MD
@drbennisahmed · X

Asundexian versus Apixaban in Patients with Atrial Fibrillation treatment with asundexian at a dose of 50 mg once daily was associated with a higher incidence of stroke or systemic embolism than treatment with apixaban https://t.co/69UQWJr6rc https://t.co/Ny1jTpw102

Jan 2, 2025 · 10 likes · 3,192 followers View post →

All mentions

Tom Hsiung
@TomHsiung · X

Effectiveness and safety of rivaroxaban vs. apixaban in patients with atrial fibrillation and peripheral artery disease https://t.co/yKRPx6fPhR

Oct 8, 2025 · 465 followers View post →
Juan Carlos Elizalde:.
@JuanElizalde777 · X

RT @ESC_Journals: Simultaneous publication during #ESCCongress Effectiveness and safety of Rivaroxaban versus Apixaban in patients with A…

Oct 2, 2025 · 20 shares · 2,395 followers View post →
Nikos Pyrpyris
@pyrpyris · X

RT @MattiaGalli10: Effectiveness and safety of rivaroxaban vs. apixaban in patients with atrial fibrillation and peripheral artery disease…

Sep 14, 2025 · 3 shares · 850 followers View post →
Abhijit Biswas
@Abhijit78446070 · X

RT @MattiaGalli10: Effectiveness and safety of rivaroxaban vs. apixaban in patients with atrial fibrillation and peripheral artery disease…

Sep 12, 2025 · 3 shares · 49 followers View post →
Felice Gragnano
@FeliceGragnano · X

RT @MattiaGalli10: Effectiveness and safety of rivaroxaban vs. apixaban in patients with atrial fibrillation and peripheral artery disease…

Sep 12, 2025 · 3 shares · 5,402 followers View post →
Mattia Galli
@MattiaGalli10 · X

Effectiveness and safety of rivaroxaban vs. apixaban in patients with atrial fibrillation and peripheral artery disease @EditorEHJCVP @FeliceGragnano @pyrpyris @ESC_Journals https://t.co/8cb6WJnJIr

Sep 12, 2025 · 9 likes · 3 shares · 3,226 followers View post →
Osama Louis
@OsamaLouis5 · X

RT @ESC_Journals: Simultaneous publication during #ESCCongress Effectiveness and safety of Rivaroxaban versus Apixaban in patients with A…

Aug 31, 2025 · 20 shares · 87 followers View post →
Tom Hsiung
@TomHsiung · X

RT @ESC_Journals: Simultaneous publication during #ESCCongress Effectiveness and safety of Rivaroxaban versus Apixaban in patients with A…

Aug 31, 2025 · 20 shares · 465 followers View post →
Dr.AMiT JAiSWAL
@aadvikmedics · X

RT @ESC_Journals: Simultaneous publication during #ESCCongress Effectiveness and safety of Rivaroxaban versus Apixaban in patients with A…

Aug 31, 2025 · 20 shares · 58 followers View post →
mahmoud_quandil
@mahmoud_quandil · X

RT @ESC_Journals: Simultaneous publication during #ESCCongress Effectiveness and safety of Rivaroxaban versus Apixaban in patients with A…

Aug 31, 2025 · 20 shares · 513 followers View post →
Riccardo Osti MD
@RashidLeDocteur · X

Effectiveness and safety of rivaroxaban vs. apixaban in patients with atrial fibrillation and peripheral artery disease https://t.co/EzBTkMXw1q #ESC2025

Aug 31, 2025 · 2 followers View post →
jabar
@turilrh · X

RT @ESC_Journals: Simultaneous publication during #ESCCongress Effectiveness and safety of Rivaroxaban versus Apixaban in patients with A…

Aug 31, 2025 · 20 shares · 1,453 followers View post →
Parham Sadeghipour
@psadeghipour · X

RT @ESC_Journals: Simultaneous publication during #ESCCongress Effectiveness and safety of Rivaroxaban versus Apixaban in patients with A…

Aug 31, 2025 · 20 shares · 369 followers View post →
Alejandro I. Pérez Cabeza
@alejandroipc2 · X

RT @ESC_Journals: Simultaneous publication during #ESCCongress Effectiveness and safety of Rivaroxaban versus Apixaban in patients with A…

Aug 30, 2025 · 20 shares · 1,170 followers View post →
maldinilin
@maldinilin · X

RT @ESC_Journals: Simultaneous publication during #ESCCongress Effectiveness and safety of Rivaroxaban versus Apixaban in patients with A…

Aug 30, 2025 · 20 shares · 97 followers View post →
Lê Văn Lắm
@levanlam95 · X

RT @ESC_Journals: Simultaneous publication during #ESCCongress Effectiveness and safety of Rivaroxaban versus Apixaban in patients with A…

Aug 30, 2025 · 20 shares · 41 followers View post →
Natsir Ramadhan
@natsiradhan · X

RT @ESC_Journals: Simultaneous publication during #ESCCongress Effectiveness and safety of Rivaroxaban versus Apixaban in patients with A…

Aug 30, 2025 · 20 shares · 557 followers View post →
Hany Ragy
@Hragy · X

RT @ESC_Journals: Simultaneous publication during #ESCCongress Effectiveness and safety of Rivaroxaban versus Apixaban in patients with A…

Aug 30, 2025 · 20 shares · 80,679 followers View post →
Syed Ali Naqvi
@SyedYNaqvi1 · X

RT @ESC_Journals: Simultaneous publication during #ESCCongress Effectiveness and safety of Rivaroxaban versus Apixaban in patients with A…

Aug 30, 2025 · 20 shares · 2,591 followers View post →
Pascal Meier,MD
@DrPascalMeier · X

RT @ESC_Journals: Simultaneous publication during #ESCCongress Effectiveness and safety of Rivaroxaban versus Apixaban in patients with A…

Aug 30, 2025 · 20 shares · 111,585 followers View post →
John P Erwin III MD MBA MACC (#BigPoppy )
@HeartOTXHeartMD · X

RT @ESC_Journals: Simultaneous publication during #ESCCongress Effectiveness and safety of Rivaroxaban versus Apixaban in patients with A…

Aug 30, 2025 · 20 shares · 39,863 followers View post →
Felipe Hernández
@pipecardio · X

RT @ESC_Journals: Simultaneous publication during #ESCCongress Effectiveness and safety of Rivaroxaban versus Apixaban in patients with A…

Aug 30, 2025 · 20 shares · 1,829 followers View post →
Xacobe Flores Rios
@xacobeflores · X

RT @ESC_Journals: Simultaneous publication during #ESCCongress Effectiveness and safety of Rivaroxaban versus Apixaban in patients with A…

Aug 30, 2025 · 20 shares · 1,203 followers View post →
Tomohiro Fujisaki
@TomohiroFujisa2 · X

RT @ESC_Journals: Simultaneous publication during #ESCCongress Effectiveness and safety of Rivaroxaban versus Apixaban in patients with A…

Aug 30, 2025 · 20 shares · 659 followers View post →
Tomohiro Fujisaki
@TomohiroFujisa2 · X

DOACの比較研究が出てきています。アピキサバンの安全性が高い結果。Effectiveness and safety of rivaroxaban vs. apixaban in patients with atrial fibrillation and peripheral artery disease https://t.co/4NXOoOjSBY

Aug 30, 2025 · 1 like · 659 followers View post →
Andres Felipe Florez
@Andresffmed · X

RT @ESC_Journals: Simultaneous publication during #ESCCongress Effectiveness and safety of Rivaroxaban versus Apixaban in patients with A…

Aug 30, 2025 · 20 shares · 159 followers View post →
EOLO MORANDI JR.
@eolojr · X

RT @ESC_Journals: Simultaneous publication during #ESCCongress Effectiveness and safety of Rivaroxaban versus Apixaban in patients with A…

Aug 30, 2025 · 20 shares · 550 followers View post →
European Society of Cardiology Journals
@ESC_Journals · X

Simultaneous publication during #ESCCongress Effectiveness and safety of Rivaroxaban versus Apixaban in patients with Atrial Fibrillation and Peripheral Artery Disease - https://t.co/HcLJEZcF8s #EHJPharmacotherapy https://t.co/BCyd7vmjNF

Aug 30, 2025 · 58 likes · 20 shares · 116,557 followers View post →
mocchi
@mocchi_ym · X

RT @drbennisahmed: Asundexian or Apixaban in Patients With Atrial Fibrillation According to Prior Oral Anticoagulant Use OCEANIC-AF Randomi…

Jun 12, 2025 · 1 share · 211 followers View post →
Ahmed Bennis MD
@drbennisahmed · X

Asundexian or Apixaban in Patients With Atrial Fibrillation According to Prior Oral Anticoagulant Use OCEANIC-AF Randomized Clinical Trial OAC-naive patients had a significantly smaller increase in stroke or systemic embolism with asundexian https://t.co/55ftteOfim https://t.co/L8xkzlVhmC

Jun 12, 2025 · 12 likes · 1 share · 3,192 followers View post →
Iyas إياس
@iyas_daghlas · X

I've been skeptical of this view based on findings from AVERROES (which didn't show higher risk of bleeding w/ apix vs ASA), though data were too imprecise to permit strong inferences. https://t.co/TIGmxzVJTF

Jun 4, 2025 · 582 followers View post →
waqar dahri
@Dahri85Waqar · X

RT @_Anesthesiology: Direct-acting oral anticoagulants prevent stroke in patients with atrial fibrillation but carry the risk of bleeding.…

May 12, 2025 · 1 share · 462 followers View post →
Anesthesiology Journals
@_Anesthesiology · X

Direct-acting oral anticoagulants prevent stroke in patients with atrial fibrillation but carry the risk of bleeding. Read a summary of "Asundexian versus apixaban in patients with atrial fibrillation" in the May 2025 SM&A: https://t.co/gy6chMvLvn https://t.co/ifXTnOk1d5

May 12, 2025 · 11 likes · 1 share · 38,359 followers View post →
the paper link
@the_paper_link · X

Trend up+11: Benkhoff M, ..., Polzin A (N Engl J Med) __Asundexian versus Apixaban in Patients with Atrial Fibrillation__ https://t.co/eLy7S3mLvU

Mar 31, 2025 · 136 followers View post →
Marko
@Markotelomerase · X

RT @SeeFisch: YOU WILL HEAR OF A FACTOR XI INHIBITOR FOR A FIB. WE do NOT THINK THIS WILL BE A GOOD DRUG Asundexian versus Apixaban in Pat…

Feb 6, 2025 · 1 share · 71 followers View post →
Conrad Fischer
@SeeFisch · X

YOU WILL HEAR OF A FACTOR XI INHIBITOR FOR A FIB. WE do NOT THINK THIS WILL BE A GOOD DRUG Asundexian versus Apixaban in Patients with Atrial Fibrillation | New England Journal of Medicine https://t.co/CSuKLC2JpI

Feb 5, 2025 · 5 likes · 1 share · 102,368 followers View post →
Diana G
@DianaGM_13 · X

RT @NEJM: Original Article: Asundexian versus Apixaban in Patients with Atrial Fibrillation https://t.co/dZPaihNNp6 #Cardiology https://t.c…

Jan 7, 2025 · 21 shares · 89 followers View post →
Jose
@Jose82044721745 · X

RT @Montecoya: Asundexian versus Apixaban in Patients with Atrial Fibrillation https://t.co/lRcxiUbDhh

Jan 6, 2025 · 2 shares · 582 followers View post →
JORGE GARCIA
@GeorgusCayo · X

RT @Montecoya: Asundexian versus Apixaban in Patients with Atrial Fibrillation https://t.co/lRcxiUbDhh

Jan 6, 2025 · 2 shares · 753 followers View post →
Sergio Calleja
@Montecoya · X

Asundexian versus Apixaban in Patients with Atrial Fibrillation https://t.co/lRcxiUbDhh

Jan 6, 2025 · 4 likes · 2 shares · 5,768 followers View post →
Eman Hassan
@Eman__Hassan__ · X

RT @DFCapodanno: The OCEANIC-AF trial, comparing asundexian to apixaban in patients with atrial fibrillation was halted early due to a sign…

Jan 4, 2025 · 32 shares · 152 followers View post →
Pao-Hsien, Chu M.D., FCCP, FACC, FESC, FAPSC
@PoChu3 · X

Asundexian versus Apixaban in Patients with Atrial Fibrillation | New England Journal of Medicine https://t.co/jiQlivlRIv

Jan 4, 2025 · 17 followers View post →
Ariel Santos
@traumamd1 · X

Asundexian - Factor XIa inhibitor versus Apixaban in Patients with Atrial Fibrillation | @NEJM Asundexian is associated with higher stroke or embolism vs. Apixaban @TTUHSCSurgery https://t.co/lCrbiFrGE0

Jan 3, 2025 · 1,350 followers View post →
The Heart
@ZHeart11768530 · X

RT @NEJM: Original Article: Asundexian versus Apixaban in Patients with Atrial Fibrillation https://t.co/dZPaihNNp6 #Cardiology https://t.c…

Jan 3, 2025 · 21 shares · 32,738 followers View post →
せいや
@kusuriawanosuke · X

次世代のDOACとして期待されたアスンデキシアンとアピキサバンとの心房細動患者に対する比較(非劣性) Asundexian versus Apixaban in Patients with Atrial Fibrillation | New England Journal of Medicine https://t.co/kAfXGviR9x

Jan 2, 2025 · 358 followers View post →
Massimo Romano
@dottmasroman · X

RT @NEJM: Original Article: Asundexian versus Apixaban in Patients with Atrial Fibrillation https://t.co/dZPaihNNp6 #Cardiology https://t.c…

Jan 2, 2025 · 21 shares · 356 followers View post →
Jakob Stensballe
@J_Stensballe · X

RT @bryanacotton1: XI vs X inhibitor RCT:

Jan 2, 2025 · 1 share · 1,301 followers View post →
Teba González-Ferrero
@tebagf · X

RT @NEJM: Original Article: Asundexian versus Apixaban in Patients with Atrial Fibrillation https://t.co/dZPaihNNp6 #Cardiology https://t.c…

Jan 2, 2025 · 21 shares · 384 followers View post →
Rodrigo Nunes Cal
@CalZole · X

RT @NEJM: Original Article: Asundexian versus Apixaban in Patients with Atrial Fibrillation https://t.co/dZPaihNNp6 #Cardiology https://t.c…

Jan 2, 2025 · 21 shares · 3,384 followers View post →
Uriel Suárez
@UsuarezMD · X

RT @NEJM: Original Article: Asundexian versus Apixaban in Patients with Atrial Fibrillation https://t.co/dZPaihNNp6 #Cardiology https://t.c…

Jan 2, 2025 · 21 shares · 3,429 followers View post →
Aghiles Hamroun
@AghilesHamroun · X

RT @NEJM: Original Article: Asundexian versus Apixaban in Patients with Atrial Fibrillation https://t.co/dZPaihNNp6 #Cardiology https://t.c…

Jan 2, 2025 · 21 shares · 722 followers View post →
AngryPhDstudent❗️❗️❗️
@ONNESHA092 · X

RT @NEJM: Original Article: Asundexian versus Apixaban in Patients with Atrial Fibrillation https://t.co/dZPaihNNp6 #Cardiology https://t.c…

Jan 2, 2025 · 21 shares · 197 followers View post →
Giuseppe Bellelli
@GiuseppeBellel1 · X

Asundexian versus Apixaban in Patients with Atrial Fibrillation | New England Journal of Medicine https://t.co/fJJ4WOXLdx

Jan 2, 2025 · 229 followers View post →
Rita Swartz
@buckleyswartz · X

RT @NEJM: Original Article: Asundexian versus Apixaban in Patients with Atrial Fibrillation https://t.co/dZPaihNNp6 #Cardiology https://t.c…

Jan 2, 2025 · 21 shares · 4,650 followers View post →
Ahmed Bennis MD
@drbennisahmed · X

Asundexian versus Apixaban in Patients with Atrial Fibrillation treatment with asundexian at a dose of 50 mg once daily was associated with a higher incidence of stroke or systemic embolism than treatment with apixaban https://t.co/69UQWJr6rc https://t.co/Ny1jTpw102

Jan 2, 2025 · 10 likes · 3,192 followers View post →
Dr. Joshuan J. Barboza
@joshuanbarbozam · X

RT @NEJM: Original Article: Asundexian versus Apixaban in Patients with Atrial Fibrillation https://t.co/dZPaihNNp6 #Cardiology https://t.c…

Jan 2, 2025 · 21 shares · 10,206 followers View post →
Bryan Cotton
@bryanacotton1 · X

XI vs X inhibitor RCT:

Jan 1, 2025 · 4 likes · 1 share · 5,042 followers View post →
Carmelo Espinosa M.D.
@carmelografo · X

RT @NEJM: Original Article: Asundexian versus Apixaban in Patients with Atrial Fibrillation https://t.co/dZPaihNNp6 #Cardiology https://t.c…

Jan 1, 2025 · 21 shares · 628 followers View post →
แม่เรียกล้างจานแล้ว
@CtherP3 · X

RT @NEJM: Original Article: Asundexian versus Apixaban in Patients with Atrial Fibrillation https://t.co/dZPaihNNp6 #Cardiology https://t.c…

Jan 1, 2025 · 21 shares · 195 followers View post →
Neo_ID เป็นพ่อมดสัตว์จิ๋ว
@1IDCNMI · X

RT @NEJM: Original Article: Asundexian versus Apixaban in Patients with Atrial Fibrillation https://t.co/dZPaihNNp6 #Cardiology https://t.c…

Jan 1, 2025 · 21 shares · 28,994 followers View post →
Manoj Mayogi Mishra
@mayogisense · X

RT @NEJM: Original Article: Asundexian versus Apixaban in Patients with Atrial Fibrillation https://t.co/dZPaihNNp6 #Cardiology https://t.c…

Jan 1, 2025 · 21 shares · 575 followers View post →
Jan Hartmann, MD
@JanHartmannMD · X

Asundexian versus Apixaban in Patients with Atrial Fibrillation | New England Journal of Medicine https://t.co/M4gpdS4xDI

Jan 1, 2025 · 307 followers View post →
Hiroshi Akazawa
@AkazawaHiroshi · X

RT @NEJM: Original Article: Asundexian versus Apixaban in Patients with Atrial Fibrillation https://t.co/dZPaihNNp6 #Cardiology https://t.c…

Jan 1, 2025 · 21 shares · 365 followers View post →
Santhosh Ambika
@RenoHemonc · X

RT @NEJM: Original Article: Asundexian versus Apixaban in Patients with Atrial Fibrillation https://t.co/dZPaihNNp6 #Cardiology https://t.c…

Jan 1, 2025 · 21 shares · 4,136 followers View post →
Elena Zapata-Arriaza
@ELeNaZapS · X

RT @NEJM: Original Article: Asundexian versus Apixaban in Patients with Atrial Fibrillation https://t.co/dZPaihNNp6 #Cardiology https://t.c…

Jan 1, 2025 · 21 shares · 1,002 followers View post →
NEJM
@NEJM · X

Original Article: Asundexian versus Apixaban in Patients with Atrial Fibrillation https://t.co/dZPaihNNp6 #Cardiology https://t.co/sx5FtVvSk5

Jan 1, 2025 · 102 likes · 21 shares · 931,827 followers View post →
ESC WG Thrombosis Chairperson
@ESCWGThrombosis · X

Explore the latest WG on #Thrombosis Paper of the Month!Our commentary dives into the OCEANIC-AF trial, comparing #asundexian and apixaban in #atrialFibrillation patients. Insights on efficacy, safety, and future directions await.

Dec 19, 2024 · 4 likes · 2 shares · 110 followers View post →
Albert Kagina Sinyigaya
@DrSinyigaya · X

RT @DrSinyigaya: Comparison of Watchman procedure with new oral anti-coagulants (Apixaban)—in patients with atrial fibrillation: A network…

Dec 3, 2024 · 1 share · 628 followers View post →
Felix Valencia
@FelixValencia10 · X

How happen with the results of AVERROES trial? It never occurred? Can we forget it? https://t.co/GHb2MhMtyn https://t.co/6SnPKjaYXp

Nov 19, 2024 · 1,718 followers View post →
AtrialFib_US
@AtrialFib_US · X

RT @ValleAlfonso:

Nov 18, 2024 · 9 shares · 1,277 followers View post →
Jahir Rodríguez - Rivera MD
@j_rdzrivera · X

RT @ValleAlfonso:

Oct 15, 2024 · 9 shares · 51 followers View post →
Luis Jara-Palomares
@luistrombo · X

RT @juanjolopezn: Asundexian versus Apixaban in Patients with Atrial Fibrillation #atrialfibrillation #asundexian #apixaban @NEJM https://t…

Oct 8, 2024 · 1 share · 603 followers View post →
Juan José López Núñez
@juanjolopezn · X

Asundexian versus Apixaban in Patients with Atrial Fibrillation #atrialfibrillation #asundexian #apixaban @NEJM https://t.co/L8NF09YWRx

Oct 7, 2024 · 1 like · 1 share · 348 followers View post →
Shreya-S
@shreya1179 · X

RT @dralexvakili: Honored to have participated as a principal site investigator, researcher and clinical research site in the Oceanic -AF A…

Sep 21, 2024 · 1 share · 238 followers View post →
.salma
@Salmammn1990 · X

RT @DrDamluji: Asundexian versus Apixaban in Patients with Atrial Fibrillation: @NEJM

Sep 21, 2024 · 8 shares · 1,319 followers View post →
Dr. B. Alex Vakili MD
@dralexvakili · X

Honored to have participated as a principal site investigator, researcher and clinical research site in the Oceanic -AF Asundexian versus Apixaban in Patients with Atrial Fibrillation clinical trial published in the NEJM September 1 issue. Unfortunately, the data did not pan out

Sep 17, 2024 · 3 likes · 1 share · 127 followers View post →
Canadian VIGOUR Centre
@CVC_UAlberta · X

RT @NEJM:

Sep 9, 2024 · 2 shares · 675 followers View post →
Eduardo Martínez
@Eduardomtzv55 · X

RT @ValleAlfonso:

Sep 8, 2024 · 9 shares · 260 followers View post →
Nada Hassib
@NadaHassib1 · X

Asundexian versus Apixaban in Patients with Atrial Fibrillation | New England Journal of Medicine https://t.co/BmnRTR0LsR

Sep 8, 2024 · 758 followers View post →
Professor M Z Khalil
@mzkhalil · X

Asundexian versus Apixaban in Patients with Atrial Fibrillation | NEJM #asundexian didn’t do the job..

Sep 6, 2024 · 2,865 followers View post →
Andres Felipe Florez
@Andresffmed · X

RT @NEJM: Original Article: Asundexian versus Apixaban in Patients with Atrial Fibrillation (OCEANIC-AF) https://t.co/dZPaihNNp6 #ESCardi…

Sep 6, 2024 · 17 shares · 159 followers View post →
Andres Felipe Florez
@Andresffmed · X

RT @DFCapodanno: The OCEANIC-AF trial, comparing asundexian to apixaban in patients with atrial fibrillation was halted early due to a sign…

Sep 6, 2024 · 32 shares · 159 followers View post →
Life Science Journal Content
@lsn_jc · X

Asundexian versus Apixaban in Patients with Atrial Fibrillation #science #publication #research #journal https://t.co/tpM6OqcGuU

Sep 6, 2024 · 267 followers View post →
Jorge Salazar M
@SalazarMJA · X

RT @NEJM:

Sep 5, 2024 · 2 shares · 399 followers View post →
NEJM
@NEJM · X

Sep 5, 2024 · 9 likes · 2 shares · 931,827 followers View post →
Jason Andrade
@DrJasonAndrade · X

@Ricky_Turgeon You have data on apixaban vs Asa in af (https://t.co/UfgSKh1dY0) though they had to be OAC ineligible…

Sep 1, 2024 · 3 likes · 8,047 followers View post →
lal0155
@lal0155 · X

RT @pinacol: デザインを解説した論文(https://t.co/o9i7Z3jbuy)を読むに、ARTESIA試験でアスピリンを対照にしたのは、この試験(https://t.co/dRuJpX0O29)で心房細動でアピキサバンvsアスピリンはこういう結果だったけど、…

Jan 12, 2024 · 1 share · 11 followers View post →
pinacol
@pinacol · X

デザインを解説した論文(https://t.co/o9i7Z3jbuy)を読むに、ARTESIA試験でアスピリンを対照にしたのは、この試験(https://t.co/dRuJpX0O29)で心房細動でアピキサバンvsアスピリンはこういう結果だったけど、AHREではどうなんだろうという疑問があったからかな。

Jan 11, 2024 · 8 likes · 1 share · 1,677 followers View post →
Jun Kim
@mdjunkim · X

Apixaban does not increase bleeding compared with ASA in warfarin intolerable AF patients. Apixaban increase bleeding compared with ASA in subclinical AF. https://t.co/BjDTornsDp

Nov 14, 2023 · 2 likes · 439 followers View post →
Seba GZ, MD, MSc
@sebagz1 · X

@SantasEnrique @secardiologia @SVCardio @clinica_sec Estos resultados van en contra de lo que mostró AVERROES, con 10 veces mas

Aug 27, 2023 · 1,644 followers View post →
Ryan Caputo, PharmD, BCCP
@RyanCaputo1 · X

@MutazAlkalbani Never aspirin based on the AVERROES trial. Less effective at preventing stroke with the same bleeding risk as apixaban. https://t.co/tdwClZtsZj

Jan 19, 2023 · 1 like · 326 followers View post →
Michal Krawczyk
@4mmk36 · X

@MedFactChecks @TotoMynell @TheSGEM @stephanamayer @ravigarg415 @Hamishmcmack "High risk population"? Based on what evidence? The risk of ICH with apixaban is likely no different from that of aspirin. https://t.co/YfvYBJZODL

Jan 10, 2023 · 1 like · 109 followers View post →
Ethan J. Weiss
@ethanjweiss · X

@matthewherper @bradloncar @BentheFidler The article, says they enrolled people with stroke but not specifically AF. If I were developing a drug in this space these days, I'd spend time studying AVVEROES but focusing on patients unwilling or unable to take DOACs. Much harder obviously today https://t.co/WfXuAspCNG

Aug 29, 2022 · 3 likes · 30,538 followers View post →
Magnus Esbjornsson
@MagEsbjornsson · X

@spraguepond The AVERROES trial showed that the risk of serious bleeding complications is equal with apixaban compared to aspirin, and provides much greater protection against stroke. https://t.co/YpiIeFtLGY The issue is - why switch to aspirin instead of reducing the dose of Eliquis as rec?

Jul 24, 2022 · 70 followers View post →
Ahmad Masri
@MasriAhmadMD · X

Will take a long time to adjust the way we think about aspirin! 10 years haven't moved the needle much https://t.co/56mkzxNSW3 #CardioTwitter https://t.co/H6dPnfkfKx

Apr 29, 2021 · 5 likes · 9,049 followers View post →
Ahmad Masri
@MasriAhmadMD · X

Finally, don't forget AVERROES findings where ASA was compared to apixaban https://t.co/56mkzxNSW3

Jan 23, 2021 · 1 like · 9,049 followers View post →
Caio de Assis Moura Tavares
@caiodeamtavares · X

5/15 More contemporary data comparing aspirin x anticoagulation (BAFTA – Warf x Aspirin (https://t.co/LGPV1rlkd4) and AVERROES – Apixaban x Aspirin (https://t.co/tyxKtLMGPq)) saw similar bleeding and increased rates of embolism with Aspirin. So less is not more, in this case

Oct 31, 2020 · 2 likes · 354 followers View post →
Ahmad Masri
@MasriAhmadMD · X

@cardskrish Excellent point - will be a discussion with the patient but if you follow prior apixaban vs aspirin, it is likely to be similar https://t.co/PGZdmbYiaM Situation is harder when patients can only afford warfarin

Dec 22, 2019 · 9,049 followers View post →
Trisha Elliott
@Trisha_the_doc · X

RT @DrDerekConnolly: @Trisha_the_doc @doc_hnaqvi and we know that aspirin has no role in older patients with NVAF after studies like BAFTA…

Oct 21, 2019 · 1 share · 16,284 followers View post →
Prof Derek Connolly
@DrDerekConnolly · X

@Trisha_the_doc @doc_hnaqvi and we know that aspirin has no role in older patients with NVAF after studies like BAFTA and Averroes https://t.co/SMA7rh6xV7

Oct 21, 2019 · 3 likes · 1 share · 3,955 followers View post →
Musa A. Sharkawi
@MusaSharkawi · X

@willsuh76 Based on the AVERROES trial, I’d go with full dose Apixiban (unless pt has 2/3 of Cr >1.5, age >80 or weight<60 kg then 2.5 mg BID). In AVERROES, aspirin and apixiban had the same rate of bleeding. https://t.co/lHT35p62Dy

Oct 2, 2019 · 11 likes · 3,312 followers View post →
Stormi Gale
@stormigale · X

@bmorecardiology @drjohnm @ATRIUMRx @MKIttlesonMD There is also similar data that suggests ASA does not decrease bleed risk in AF compared to apixaban: https://t.co/RidYMhmJMK

Sep 25, 2019 · 8 likes · 1,952 followers View post →
Ahmad Masri
@MasriAhmadMD · X

@TYWangMD Havent seen the trial results. But based on this: https://t.co/PGZdmbYiaM Would always go with DOAC over a procedure, a shaky pathophys, a nidus for thrombi, and dapt

Sep 2, 2019 · 9,049 followers View post →
Vass Vassiliou
@vass_vassiliou · X

@savodoc @drstephenpettit @drjasondungu @JGrapsa @Apple ...bleeding risk not different between aspirin and a NOAC, so in this case I would recommend a NOAC. @venkmurthy will have views about Apple Watch - but at present I wouldn’t recommend it for this patient... https://t.co/wEpMehNDO1

Jul 20, 2019 · 2 likes · 10,213 followers View post →
Ben Cole
@brwcole · X

@RodrigoEstvez1 @miguelpinon_73 @aidanraneymd @HeartDrHanna @dngibson2 @joewalshmd The bleeding risk of apixiban was no worse than aspirin in Averoes https://t.co/YJi0MbhpfN

Jun 19, 2019 · 297 followers View post →