March 2011 PMID 21366472

Diuretic strategies in patients with acute decompensated heart failure.

G Michael Felker, Kerry L Lee, David A Bull, Margaret M Redfield, Lynne W Stevenson, Steven R Goldsmith, Martin M LeWinter, Anita Deswal, Jean L Rouleau, Elizabeth O Ofili, Kevin J Anstrom, Adrian F Hernandez, Steven E McNulty, Eric J Velazquez, Abdallah G Kfoury

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Mentions

113

Peak: 7 in Dec 2020

across 6 sources since Jan 2019

Extended reach

379,702

potential audience

Total likes

287

Video views

3,393

Mentions per month

Jan 2019 – Mar 2025

Where it's discussed

X / Twitter75 posts
News17 articles
Blogs11 articles
Facebook6 posts
YouTube3 videos
Bluesky1 posts

AI synopsis

What people are saying

The overall discussion demonstrates strong engagement through references to the NEJM trial, with phrases like 'no significant difference' and 'infusion vs bolus,' illustrating nuanced debates about diuretic strategies and their clinical implications. The tone varies from informative to analytical, with many examples emphasizing the relevance of trial outcomes for treatment decisions.

AgreementModerate agreement

Most posts agree that the study shows similar outcomes for different diuretic strategies, but some emphasize advantages of infusion in specific settings.

InterestHigh interest

Discussions reveal high interest, with multiple mentions of trial results, implications for practice, and references to specific studies.

EngagementHigh engagement

Posts are quite detailed, referencing trial data, sharing opinions on dosing methods, and debating clinical relevance, reflecting deep engagement.

ImpactModerate impact

While some recognize the trial's importance in shaping diuretic strategies, others see it as one of many pieces in a complex decision-making process, indicating moderate impact.

All mentions

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Congestive Heart Failure Treatment in Chronic Kidney Disease Patients

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Sí

@OswaldoSuastegu · X

RT @niklaus2009: Da igual usar bolos de furosemide que infusión continua en Insuficiencia cardiaca aguda https://t.co/Z4vYOoikrQ

Mar 28, 2025 · 2 shares · 340 followers View post →

Luis Ma

@luisma1820 · X

RT @niklaus2009: Da igual usar bolos de furosemide que infusión continua en Insuficiencia cardiaca aguda https://t.co/Z4vYOoikrQ

Mar 9, 2025 · 2 shares · 439 followers View post →

Homero Malandro

@niklaus2009 · X

Da igual usar bolos de furosemide que infusión continua en Insuficiencia cardiaca aguda https://t.co/Z4vYOoikrQ

Mar 8, 2025 · 18 likes · 2 shares · 12,350 followers View post →

茨城の「墨子」に俺はなる！ひたちなかGIM：柴﨑俊一

@sn1shibazaki · X

＃常陸田舎の総合内科　＃とある日常

Feb 4, 2025 · 2 likes · 7,364 followers View post →

nao

@nao_01_ · X

https://t.co/M7UhHfgltY フロセミドの持続投与って意味あるのか？ほとんどなさそう。

Oct 7, 2024 · 698 followers View post →

no kazumasa|pharmacist

@nokazumasa · X

RT @ken_korai: 心不全でのループ利尿薬 ✔︎閾値が上昇 ✔︎効果の減弱 https://t.co/UCCCzmcSib つまり十分な量を投与する必要あり複数回投与か、持続で尿量をかせぐただし、DOSEでは単回・持続の差はなし https://t.co/QOB…

Sep 21, 2024 · 3 shares · 437 followers View post →

Sol

@ArualSogar · X

RT @clinicasac:

Aug 13, 2024 · 2 shares · 798 followers View post →

Consejo de Cardiología Clínica y Terapéutica

@clinicasac · X

Aug 11, 2024 · 5 likes · 2 shares · 8,155 followers View post →

みや

@1ch1go1ch1e · X

RT @autumnleaveskid: Xでフロセミドの話になってたからDOSE試験(2011)紹介。フロセミドの持続静注と間欠投与で臨床症状改善や60日時点の予後に有意差なし。あと、高容量群の方がCrは高くなるけど、早めに臨床症状は改善するし60日時点での予後も関係なかった…

Jun 17, 2024 · 2 shares · 3,562 followers View post →

Hirotsugu Kitayama

@HirotsuguKitay1 · X

Jun 17, 2024 · 2 shares · 175 followers View post →

おちば@腎臓内科

@autumnleaveskid · X

Jun 17, 2024 · 42 likes · 2 shares · 4,031 followers View post →

Pharmacy To Dose: The Critical Care Podcast

@PharmacyToDose · X

Mar 20, 2024 · 6,838 followers View post →

Bernard Kadosh

@KadoshBernard · X

@PrakashUpretiMD @RandyGoldbergMD @ReyentovichHFMD @SVRaoMD @JasonKatzMD Look at the renal outcomes here: https://t.co/OrVZgzrxab

Feb 12, 2024 · 3 likes · 1,006 followers View post →

Hassan Ali Beg

@NotoriousB_E_G · X

@jackbardwell99 @DrDavidWarriner No difference overall. I prefer bolus dosing so the patient isn't encumbered by being attached to a drip all the time. https://t.co/bYFruq385C

Dec 20, 2023 · 3 likes · 1,851 followers View post →

yatoo

@yatoo0077 · X

DOSE trial https://t.co/T6A3RlyYGo

Sep 27, 2023 · 1 like · 315 followers View post →

Diana Lasso

@purpuracafe · X

RT @javier20ch: ✍️Bibliografias: ✨️Revisión: https://t.co/wSEQ80eSLU ✨️Artículos originales: https://t.co/lvY731FBhC https://t.co/OMxIuifK…

Feb 10, 2023 · 7 shares · 16 followers View post →

Wagner Paul

@gzwagner · X

RT @javier20ch: ✍️Bibliografias: ✨️Revisión: https://t.co/wSEQ80eSLU ✨️Artículos originales: https://t.co/lvY731FBhC https://t.co/OMxIuifK…

Feb 10, 2023 · 7 shares · 159 followers View post →

lucero

@lucymatsu · X

RT @javier20ch: ✍️Bibliografias: ✨️Revisión: https://t.co/wSEQ80eSLU ✨️Artículos originales: https://t.co/lvY731FBhC https://t.co/OMxIuifK…

Feb 9, 2023 · 7 shares · 153 followers View post →

Onofre Casas Castro

@onofre_casas · X

RT @javier20ch: ✍️Bibliografias: ✨️Revisión: https://t.co/wSEQ80eSLU ✨️Artículos originales: https://t.co/lvY731FBhC https://t.co/OMxIuifK…

Feb 9, 2023 · 7 shares · 110 followers View post →

Ricardo Bedón

@ricardo_bedon · X

RT @javier20ch: ✍️Bibliografias: ✨️Revisión: https://t.co/wSEQ80eSLU ✨️Artículos originales: https://t.co/lvY731FBhC https://t.co/OMxIuifK…

Feb 9, 2023 · 7 shares · 1,504 followers View post →

Dr. FEVI

@javier20ch · X

✍️Bibliografias: ✨️Revisión: https://t.co/wSEQ80eSLU ✨️Artículos originales: https://t.co/lvY731FBhC https://t.co/OMxIuifKEg https://t.co/QjdfxraRgt

Feb 9, 2023 · 17 likes · 7 shares · 13,596 followers View post →

ACCP CRIT PRN

@accpcritprn · X

According to the #DOSE trial, which utilized furosemide for ADHF, only 15% of patients had no clinical congestion after 72 hours of treatment. https://t.co/XyiSMNepke #CritPRNjc

Nov 8, 2022 · 3 likes · 7,505 followers View post →

Hirotsugu Kitayama

@HirotsuguKitay1 · X

Oct 10, 2022 · 3 shares · 175 followers View post →

Gabu

@lX1IithG4dsRYVi · X

Oct 9, 2022 · 3 shares · 816 followers View post →

高麗謙吾@心臓

@ken_korai · X

Oct 9, 2022 · 28 likes · 3 shares · 11,227 followers View post →

Kimitaka Nishizaki

@nishiki8885 · X

フロセミド単回投与 vs 持続投与どちらも大きな差はない → DOSE trial ですね！ NEJM (https://t.co/vfo4rFma61) アルブミンと利尿作用は関係ない？！ CJASN →炎症性マーカーと関連があり、低アルブミンはサロゲートマーカーの可能性！！

Oct 8, 2022 · 9 likes · 2,962 followers View post →

Syed Shahrul Naz

@drshahrul80 · X

RT @captainchloride: Only a minority of patients in the DOSE trial, which used high dose diuretics were free from congestion at 72 hours h…

Sep 20, 2022 · 1 share · 6,928 followers View post →

Nayan Arora

@captainchloride.bsky.social · Bluesky

Only a minority of patients in the DOSE trial, which used high dose diuretics were free from congestion at 72 hours https://www.nejm.org/doi/full/10.1056/nejmoa1005419

Sep 20, 2022 · 1 share View post →

Nayan Arora,MD

@captainchloride · X

Only a minority of patients in the DOSE trial, which used high dose diuretics were free from congestion at 72 hours https://t.co/Y7IJ1J8MY8 https://t.co/bsAzUbbK6w

Sep 20, 2022 · 7 likes · 1 share · 3,409 followers View post →

McGaw Medical Center of Northwestern University

@McGawGME · X

RT @NU_IntMed: #Noon Conference: "Diuretic Strategies in Patients with Acute Decompensated Heart Failure" from NEJM - Journal Club with Dr.…

Jul 19, 2022 · 1 share · 1,792 followers View post →

NU Internal Medicine

@NU_IntMed · X

#Noon Conference: "Diuretic Strategies in Patients with Acute Decompensated Heart Failure" from NEJM - Journal Club with Dr. Lee and Content Expert Dr. Anand Srivastava

Jul 19, 2022 · 3 likes · 1 share · 5,520 followers View post →

Antonio García

@Volknergarcia · X

RT @javier20ch: Conclusiones: bolo o infusión da igual, dosis altas es mejor (>2.5), inicio temprano del tratamiento (<60 min) y UF como úl…

May 22, 2022 · 1 share · 10 followers View post →

Dr. FEVI

@javier20ch · X

Conclusiones: bolo o infusión da igual, dosis altas es mejor (>2.5), inicio temprano del tratamiento (<60 min) y UF como última opción.

May 21, 2022 · 2 likes · 1 share · 13,596 followers View post →

Facundo Balsano

@fbalsanoMD · X

RT @CONAREC_ORG: Para leer completo este articulo puedes ingresar a la web por este enlace

May 3, 2022 · 1 share · 316 followers View post →

CONAREC

@CONAREC_ORG · X

Para leer completo este articulo puedes ingresar a la web por este enlace

May 2, 2022 · 5 likes · 1 share · 4,970 followers View post →

Wilfried Mullens

@WilfriedMullens · X

Only 15% of AHF included in DOSE trial were decongested after 72 hours of high-dose loop diuretic (LD) therapy (3/9). https://t.co/qqJwutZWQD https://t.co/icaAg47tgC

Apr 27, 2022 · 15 likes · 4,189 followers View post →

David Winchester @drdavemd.bsky.social

@drdavemd · X

8. DOSE trial showed similar outcomes with bolus vs infusion of furosemide, but remember that infusion gives the patient a longer period of the day in the adequate therapeutic window and don't be afraid to switch to infusion if bolus isn't working. https://t.co/6oy2kqijSQ

Mar 28, 2022 · 1 like · 1,011 followers View post →

Dr Priti MD,FASN

@priti899 · X