Annu Rev Biochem October 2011 PMID 21495847

The structure of the nuclear pore complex.

André Hoelz, Erik W Debler, Günter Blobel

Mentions

49
Peak: 13 in Apr 2023
across 3 sources since May 2012

Extended reach

348,811
potential audience

Total likes

186

Video views

54,326

Mentions per month

May 2012 – Oct 2024

Where it's discussed

  • X / Twitter43 posts
  • YouTube4 videos
  • News2 articles

AI synopsis

What people are saying

The discussions highlight excitement over advances like AlphaFold and cryo-electron microscopy, with posts using words like 'awe inspiring' and 'impressive,' indicating strong enthusiasm and recognition of the research's importance. For example, comments celebrating the Nobel Prize and emphasizing 'good science keeps improving' reveal a tone of admiration and engagement with the scientific process.

AgreementModerate agreement

Most discussions express admiration and recognition for the scientific achievements in resolving the nuclear pore complex, indicating strong agreement with the significance of this research.

InterestHigh interest

The posts show high interest, referencing innovative techniques like cryo-electron microscopy and AlphaFold, and celebrating breakthroughs and awards.

EngagementHigh engagement

Many posts delve into technical details, referencing specific methods (e.g., cryo-EM, AlphaFold) and historical context, showing deep engagement.

ImpactModerate impact

While the community clearly values the scientific impact, most comments focus on acknowledgment and appreciation rather than discussing broader societal or technological impacts.

Abstract in brief

  • The nuclear pore complex (NPC) is essential for transporting molecules between the nucleus and cytoplasm in eukaryotic cells, acting as a gateway facilitated by transport receptors.
  • Recent scientific advances have started to reveal the atomic-level structure of the NPC, shedding light on its overall architecture and design principles.
  • Despite these progressions, there are still important questions and challenges remaining in fully understanding the NPC's detailed structure and function, which may also inform studies of other large protein assemblies.]

Top posts

Most liked on X and Bluesky
Tim Green
@tfgg2 · X

Really cool to see heavy use of AlphaFold in this special issue of @ScienceMagazine about building the structure of the nuclear pore complex https://t.co/2zgt2EgSPN https://t.co/ri3DfZrMJ7

Jun 9, 2022 · 61 likes · 7 shares · 2,886 followers View post →
Sadaf Shadan
@sshadan · X

Much is known about the structure of the nuclear pore complex (NPC) scaffold. But our image of the ~50-MDa FG-NUPs at the centre of the NPC has remained a ~60-nm hole – until now. See the article below @nature. https://t.co/T1OnAALd90

Apr 26, 2023 · 58 likes · 14 shares · 2,586 followers View post →
Josh Wolfe
@wolfejosh · X

Jun 9, 2022 · 33 likes · 5 shares · 167,100 followers View post →
NaN demeulemeester
@snikolov · X

it's genuinely awe inspiring they were able to resolve the structure of the nuclear pore complex. This is a really cool interactive tool to explore it https://t.co/a63zkjUeWo

Oct 22, 2024 · 8 likes · 4,350 followers View post →
Gallego Lab
@GallegoLab · X

Cryo-Electron Tomography in Xenopus oocytes to analyse the structure of the Nuclear Pore Complex https://t.co/uwmmev5RbP

Mar 29, 2020 · 8 likes · 1 share · 677 followers View post →
Dr. Anita Corbett- (She/her)
@acorbe2 · X

Great morning of talks about how far we have come on understanding the structure of the nuclear pore complex- amazing how the field has progressed since this very early cartoon! #LifeAtTheEdge #Potsdam https://t.co/q1jnLRWGvG

Jul 21, 2022 · 6 likes · 1 share · 2,408 followers View post →

All mentions

Natalie Marleny
@NatalieMarleny · X

RT @SnorkleLabs: Congrats again to the winners of the @NobelPrize in Chemistry! One of the most epic achievements of their innovative #Alph…

Oct 22, 2024 · 3 shares · 7,526 followers View post →
NaN demeulemeester
@snikolov · X

it's genuinely awe inspiring they were able to resolve the structure of the nuclear pore complex. This is a really cool interactive tool to explore it https://t.co/a63zkjUeWo

Oct 22, 2024 · 8 likes · 4,350 followers View post →
Jonathan Fisher
@fisherworks · X

RT @SnorkleLabs: Congrats again to the winners of the @NobelPrize in Chemistry! One of the most epic achievements of their innovative #Alph…

Oct 14, 2024 · 3 shares · 196 followers View post →
Snorkle Labs
@SnorkleLabs · X

Congrats again to the winners of the @NobelPrize in Chemistry! One of the most epic achievements of their innovative #AlphaFold was solving the structure of the nuclear pore complex, which you can interact with here! https://t.co/T4W84chwq0 https://t.co/oZ2pUD9Cil

Oct 14, 2024 · 5 likes · 3 shares · 19 followers View post →
Justin Williams
@JustJPW · X

I remember the 2015 Winter NYSBDG had the same group use an integrated structural bio approach to solve the structure of the nuclear pore complex Good science keeps improving!

Mar 29, 2024 · 1 like · 56 followers View post →
Journal of Molecular Biology
@JMolBiol · X

Our 7th most downloaded article of 2023 is “Cryo-electron Microscopy Reveals the Structure of the Nuclear Pore Complex” by @TLinhua, Guoliang Yin , Fei Sun, and Yun Zhu https://t.co/eidI25gr4q https://t.co/t1hCI55i3u

Dec 27, 2023 · 2 likes · 4,816 followers View post →
Dr. Anita Corbett- (She/her)
@acorbe2 · X

Congrats to @RoutLab_RU on this impressive tour de force providing insight into the structure of the nuclear pore complex in yeast! https://t.co/JXMuZpVoQJ

Oct 5, 2023 · 1 like · 2,408 followers View post →
Lemke Lab
@LemkeLab · X

RT @sshadan: Much is known about the structure of the nuclear pore complex (NPC) scaffold. But our image of the ~50-MDa FG-NUPs at the cent…

Apr 29, 2023 · 14 shares · 1,640 followers View post →
Raghav Ramabadran
@BMSplice · X

RT @sshadan: Much is known about the structure of the nuclear pore complex (NPC) scaffold. But our image of the ~50-MDa FG-NUPs at the cent…

Apr 27, 2023 · 14 shares · 194 followers View post →
Phenomics
@Phenomics_J · X

RT @sshadan: Much is known about the structure of the nuclear pore complex (NPC) scaffold. But our image of the ~50-MDa FG-NUPs at the cent…

Apr 26, 2023 · 14 shares · 1,523 followers View post →
J. Fernando Bazan @jfernandobazan.bsky.social
@jfernandobazan · X

RT @sshadan: Much is known about the structure of the nuclear pore complex (NPC) scaffold. But our image of the ~50-MDa FG-NUPs at the cent…

Apr 26, 2023 · 14 shares · 706 followers View post →
Jaehoon Jung
@JungLab_SKKU · X

RT @sshadan: Much is known about the structure of the nuclear pore complex (NPC) scaffold. But our image of the ~50-MDa FG-NUPs at the cent…

Apr 26, 2023 · 14 shares · 176 followers View post →
Mahmoud Qutb
@MahmoudTony19 · X

RT @sshadan: Much is known about the structure of the nuclear pore complex (NPC) scaffold. But our image of the ~50-MDa FG-NUPs at the cent…

Apr 26, 2023 · 14 shares · 245 followers View post →
Keiichi Ito
@itok10918 · X

RT @sshadan: Much is known about the structure of the nuclear pore complex (NPC) scaffold. But our image of the ~50-MDa FG-NUPs at the cent…

Apr 26, 2023 · 14 shares · 1,243 followers View post →
Bappaditya Chandra
@ChandraLabNDSU · X

RT @sshadan: Much is known about the structure of the nuclear pore complex (NPC) scaffold. But our image of the ~50-MDa FG-NUPs at the cent…

Apr 26, 2023 · 14 shares · 496 followers View post →
Veronica R Bravo
@VRodriguezBravo · X

RT @sshadan: Much is known about the structure of the nuclear pore complex (NPC) scaffold. But our image of the ~50-MDa FG-NUPs at the cent…

Apr 26, 2023 · 14 shares · 899 followers View post →
TanjaMittag
@TanjaMittag · X

RT @sshadan: Much is known about the structure of the nuclear pore complex (NPC) scaffold. But our image of the ~50-MDa FG-NUPs at the cent…

Apr 26, 2023 · 14 shares · 2,528 followers View post →
Miao Yu
@MiaoooYu · X

RT @sshadan: Much is known about the structure of the nuclear pore complex (NPC) scaffold. But our image of the ~50-MDa FG-NUPs at the cent…

Apr 26, 2023 · 14 shares · 422 followers View post →
SPP2191 - Mol. Mech. of Funct. Phase Separation
@SPP2191 · X

RT @sshadan: Much is known about the structure of the nuclear pore complex (NPC) scaffold. But our image of the ~50-MDa FG-NUPs at the cent…

Apr 26, 2023 · 14 shares · 897 followers View post →
Sadaf Shadan
@sshadan · X

Much is known about the structure of the nuclear pore complex (NPC) scaffold. But our image of the ~50-MDa FG-NUPs at the centre of the NPC has remained a ~60-nm hole – until now. See the article below @nature. https://t.co/T1OnAALd90

Apr 26, 2023 · 58 likes · 14 shares · 2,586 followers View post →
Tim Duignan
@TimothyDuignan · X

@pauldauenhauer Predicting the structure of a protein from its sequence. One particularly cool/important application I thought was determining the structure of the nuclear pore complex https://t.co/BCWmHtivmk

Mar 22, 2023 · 6,224 followers View post →
Dr. Shashank Joshi
@AskDrShashank · X

RT @acorbe2: Great morning of talks about how far we have come on understanding the structure of the nuclear pore complex- amazing how the…

Jul 21, 2022 · 1 share · 32,536 followers View post →
Dr. Anita Corbett- (She/her)
@acorbe2 · X

Great morning of talks about how far we have come on understanding the structure of the nuclear pore complex- amazing how the field has progressed since this very early cartoon! #LifeAtTheEdge #Potsdam https://t.co/q1jnLRWGvG

Jul 21, 2022 · 6 likes · 1 share · 2,408 followers View post →
Praveena Kode
@praveenakode · X

RT @wolfejosh:

Jun 10, 2022 · 5 shares · 376 followers View post →
Suhnylla Kler
@SuhnyllaKler · X

RT @tfgg2: Really cool to see heavy use of AlphaFold in this special issue of @ScienceMagazine about building the structure of the nuclear…

Jun 10, 2022 · 7 shares · 1,565 followers View post →
Daniel S.
@asecretcrow · X

RT @tfgg2: Really cool to see heavy use of AlphaFold in this special issue of @ScienceMagazine about building the structure of the nuclear…

Jun 10, 2022 · 7 shares · 535 followers View post →
Louis Maddox
@biochemistries · X

RT @tfgg2: Really cool to see heavy use of AlphaFold in this special issue of @ScienceMagazine about building the structure of the nuclear…

Jun 10, 2022 · 7 shares · 1,488 followers View post →
Kevin Nejad
@kevin_nejad · X

RT @tfgg2: Really cool to see heavy use of AlphaFold in this special issue of @ScienceMagazine about building the structure of the nuclear…

Jun 10, 2022 · 7 shares · 308 followers View post →
David Pfau
@pfau · X

RT @tfgg2: Really cool to see heavy use of AlphaFold in this special issue of @ScienceMagazine about building the structure of the nuclear…

Jun 10, 2022 · 7 shares · 29,169 followers View post →
MATSUMOTO Yutaka
@yutakama · X

RT @tfgg2: Really cool to see heavy use of AlphaFold in this special issue of @ScienceMagazine about building the structure of the nuclear…

Jun 9, 2022 · 7 shares · 3,179 followers View post →
Alex Nova
@PdxNova · X

RT @wolfejosh:

Jun 9, 2022 · 5 shares · 1,359 followers View post →
Andrew Hires
@AndrewHires · X

RT @wolfejosh:

Jun 9, 2022 · 5 shares · 6,901 followers View post →
Archimedes
@ArchimedesInte2 · X

RT @wolfejosh:

Jun 9, 2022 · 5 shares · 575 followers View post →
Josh Wolfe
@wolfejosh · X

Jun 9, 2022 · 33 likes · 5 shares · 167,100 followers View post →
Tim Green
@tfgg2 · X

Really cool to see heavy use of AlphaFold in this special issue of @ScienceMagazine about building the structure of the nuclear pore complex https://t.co/2zgt2EgSPN https://t.co/ri3DfZrMJ7

Jun 9, 2022 · 61 likes · 7 shares · 2,886 followers View post →
Isatou Sarr
@IsatouSarr4 · X

The Structure of the Nuclear Pore Complex (An Update) https://t.co/2fZCABLOhy

Dec 22, 2021 · 1 like · 34 followers View post →
MyJournals
@myjournals · X

The Structure of the Nuclear Pore Complex (An Update) https://t.co/ty1QPOh9uF

May 14, 2020 · 556 followers View post →
Arun
@ArunCellBiology · X

RT @GallegoLab: Cryo-Electron Tomography in Xenopus oocytes to analyse the structure of the Nuclear Pore Complex

Mar 29, 2020 · 1 share · 148 followers View post →
Gallego Lab
@GallegoLab · X

Cryo-Electron Tomography in Xenopus oocytes to analyse the structure of the Nuclear Pore Complex https://t.co/uwmmev5RbP

Mar 29, 2020 · 8 likes · 1 share · 677 followers View post →
Michael Goodin
@goodinbiotech · X

The Structure of the Nuclear Pore Complex (An Update) | Annual Review of Biochemistry https://t.co/D4yHyUh56c

Jun 26, 2019 · 89 followers View post →
Prehna Lab
@prehnalab · X

RT @MBMicrobiology: MGPSF Seminar: The Structure of the Nuclear Pore Complex; Dr. André Hoelz California Institute of Technology Apr 29 3:3…

Apr 23, 2019 · 2 shares · 1,472 followers View post →
MiSC U of M
@UofmMicroclub · X

RT @MBMicrobiology: MGPSF Seminar: The Structure of the Nuclear Pore Complex; Dr. André Hoelz California Institute of Technology Apr 29 3:3…

Apr 23, 2019 · 2 shares · 305 followers View post →
ManitobaMicrobiology
@MBMicrobiology · X

MGPSF Seminar: The Structure of the Nuclear Pore Complex; Dr. André Hoelz California Institute of Technology Apr 29 3:30, 207 Buller University of Manitoba: Faculty of Science @UofMMicroClub #um_microbio @UManitobaSciDn @UMmicrogsa https://t.co/YVyRTL1nah

Apr 23, 2019 · 2 likes · 2 shares · 1,121 followers View post →