Annu Rev Biomed Eng August 2011 PMID 21529164

In vitro models of traumatic brain injury.

Barclay Morrison, Benjamin S Elkin, Jean-Pierre Dollé, Martin L Yarmush

Mentions

8
Peak: 4 in Sep 2021
across 2 sources since Apr 2012

Extended reach

92,536
potential audience

Total likes

16

Video views

1,043

Mentions per month

Apr 2012 – Apr 2023

Where it's discussed

  • X / Twitter6 posts
  • YouTube2 videos

AI synopsis

What people are saying

The social discussions are quite positive and focused, with posts referencing systematic reviews, methodological studies, and potential therapeutic advances, emphasizing the importance of model fidelity and translational success. Words like 'systematic review,' 'accuracy,' and 'therapeutic' indicate a focus on scientific rigor and practical impact, reflecting active engagement and recognition of the research's significance.

AgreementModerate agreement

Most posts acknowledge the value and relevance of in vitro models for TBI research, indicating general support.

InterestHigh interest

Discussions reflect high curiosity, with posts referencing specific models, systematic reviews, and therapeutic potentials.

EngagementModerate engagement

Posts show moderate engagement, including mentions of methods, summaries of articles, and implications for future research.

ImpactModerate impact

While recognizing the significance, posts suggest that these models could notably influence TBI treatment strategies, but some remain cautious about current limitations.

Abstract in brief

  • In vitro models of traumatic brain injury (TBI) are used to understand the biological processes that lead to cell damage and death after brain trauma, and to identify potential therapeutic compounds.
  • The effectiveness of these models depends on how accurately they replicate the cellular and molecular events seen in actual TBI cases in living organisms, with current models showing over 88% predictive success in translating findings to in vivo results.
  • The review discusses various in vitro models, injury mechanisms, and testing of compounds, emphasizing their role in advancing TBI treatment research while highlighting the importance of model fidelity to complex real-world brain injuries.]

Top posts

Most liked on X and Bluesky
Journal of Neurotrauma
@J_Neurotrauma · X

In Vitro Models of Traumatic Brain Injury: A Systematic Review The aim of this review is to examine in vitro TBI studies conducted from 2008-2018 to better understand the TBI in vitro model available in the literature. DOI: 10.1089/neu.2020.7402 https://t.co/MHxK3inzO4

Sep 10, 2021 · 11 likes · 3 shares · 957 followers View post →
Frontiers - Neuroscience
@FrontNeurosci · X

New Research: Dorsal root ganglion neurons recapitulate the traumatic axonal injury of CNS neurons in response to a rapid stretch in vitro: Introduction:In vitro models of traumatic brain injury (TBI) commonly use neurons isolated from the… https://t.co/5TbPksqDVM #neuroscience

Apr 10, 2023 · 5 likes · 81,228 followers View post →
SystematicReviewBot
@EvidenceRobot · X

RT @J_Neurotrauma: In Vitro Models of Traumatic Brain Injury: A Systematic Review The aim of this review is to examine in vitro TBI studies…

Sep 10, 2021 · 3 shares · 6,693 followers View post →
David Loane
@davidjloane · X

RT @J_Neurotrauma: In Vitro Models of Traumatic Brain Injury: A Systematic Review The aim of this review is to examine in vitro TBI studies…

Sep 10, 2021 · 3 shares · 1,256 followers View post →
David L. Brody
@DavidLBrody1 · X

RT @J_Neurotrauma: In Vitro Models of Traumatic Brain Injury: A Systematic Review The aim of this review is to examine in vitro TBI studies…

Sep 10, 2021 · 3 shares · 786 followers View post →
MyJournals
@myjournals · X

IJMS, Vol. 24, Pages 3334: P188 Therapy in In Vitro Models of Traumatic Brain Injury https://t.co/TwRq3kWoyC

Feb 7, 2023 · 550 followers View post →

All mentions

Frontiers - Neuroscience
@FrontNeurosci · X

New Research: Dorsal root ganglion neurons recapitulate the traumatic axonal injury of CNS neurons in response to a rapid stretch in vitro: Introduction:In vitro models of traumatic brain injury (TBI) commonly use neurons isolated from the… https://t.co/5TbPksqDVM #neuroscience

Apr 10, 2023 · 5 likes · 81,228 followers View post →
MyJournals
@myjournals · X

IJMS, Vol. 24, Pages 3334: P188 Therapy in In Vitro Models of Traumatic Brain Injury https://t.co/TwRq3kWoyC

Feb 7, 2023 · 550 followers View post →
David Loane
@davidjloane · X

RT @J_Neurotrauma: In Vitro Models of Traumatic Brain Injury: A Systematic Review The aim of this review is to examine in vitro TBI studies…

Sep 10, 2021 · 3 shares · 1,256 followers View post →
SystematicReviewBot
@EvidenceRobot · X

RT @J_Neurotrauma: In Vitro Models of Traumatic Brain Injury: A Systematic Review The aim of this review is to examine in vitro TBI studies…

Sep 10, 2021 · 3 shares · 6,693 followers View post →
David L. Brody
@DavidLBrody1 · X

RT @J_Neurotrauma: In Vitro Models of Traumatic Brain Injury: A Systematic Review The aim of this review is to examine in vitro TBI studies…

Sep 10, 2021 · 3 shares · 786 followers View post →
Journal of Neurotrauma
@J_Neurotrauma · X

In Vitro Models of Traumatic Brain Injury: A Systematic Review The aim of this review is to examine in vitro TBI studies conducted from 2008-2018 to better understand the TBI in vitro model available in the literature. DOI: 10.1089/neu.2020.7402 https://t.co/MHxK3inzO4

Sep 10, 2021 · 11 likes · 3 shares · 957 followers View post →