PLoS One April 2011 PMID 21533091

Reversal of diabetic nephropathy by a ketogenic diet.

Michal M Poplawski, Jason W Mastaitis, Fumiko Isoda, Fabrizio Grosjean, Feng Zheng, Charles V Mobbs

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Mentions

46
Peak: 7 in Sep 2022
across 3 sources since Apr 2019

Extended reach

415,197
potential audience

Total likes

2,145

Video views

56,759

Mentions per month

Apr 2019 – May 2025

Where it's discussed

  • X / Twitter43 posts
  • YouTube2 videos
  • Bluesky1 posts

AI synopsis

What people are saying

Discussions reflect strong support and curiosity about the research, with posts emphasizing the potential of ketogenic diets to reverse diabetic kidney damage, such as phrases like 'completely reversed' and 'implications for treatment,' which illustrate both enthusiasm and critical reflection on the study's significance and limitations.

AgreementModerate agreement

Most discussions support the findings of the study, viewing it as promising evidence for the therapeutic potential of ketogenic diets in reversing kidney damage caused by diabetes.

InterestHigh interest

The majority of interactions show high curiosity and engagement with the topic, especially regarding the mechanisms and implications of the research.

EngagementHigh engagement

Many posts reference specific studies, criticize or praise research methods, and debate clinical relevance, indicating deep interaction with the subject matter.

ImpactModerate impact

While some users acknowledge the significant potential impact of the findings, there is still skepticism and calls for further research, showing moderate perceived influence.

Abstract in brief

  • The study explored whether a ketogenic diet, which increases levels of the ketone 3-hydroxybutyric acid (3OHB), could reverse diabetic nephropathy, a complication of diabetes affecting the kidneys.
  • In mouse models with Type 1 and Type 2 diabetes, switching to a ketogenic diet after nephropathy had developed completely reversed some molecular markers and reduced albuminuria, indicating improvement in kidney function, though some structural damage remained.
  • The findings suggest that a ketogenic diet may be a simple and effective way to reverse diabetic nephropathy, but further research is needed to understand if the benefits are due to reduced glucose metabolism or other mechanisms.]

Top posts

Most liked on X and Bluesky
Valerie, RD, MPH
@RDValerie · X

We need to start referencing these studies, and not just cherry-picking research that is not aligned with physiology: Reversal of Diabetic Nephropathy by a Ketogenic Diet. Sad thing is, show people this, they will still deny and cite dangers of keto. https://t.co/ZPKsszXR97

Dec 4, 2019 · 12 likes · 2 shares · 33,962 followers View post →
Travis Statham
@Travis_Statham · X

https://t.co/s8MNbI6GMd ‘Reversal of Diabetic Nephropathy by a Ketogenic Diet’ This infuriates me. RD gets 15 minutes more time for patient on dialysis. #Ketogenic diet reverses DN In 2 months. #Dietitians are not even heroes. They are frauds. https://t.co/vzPFU27tTa

Jun 14, 2019 · 11 likes · 3 shares · 12,696 followers View post →
JT | Jerry Teixeira
@jerryteixeira · X

@RDValerie https://t.co/0BbsqCLnyR

Dec 4, 2019 · 9 likes · 79,420 followers View post →
JT | Jerry Teixeira
@jerryteixeira · X

@JoseAntonioPhD @DrHorwitz @DeanOrnishMD @mackinprof OP forgets to mention in his tweet that the studies are talking about those who may already have kidney issues due to diabetes. Also here is a study showing reversal of Diabetic Nephropathy with a ketogenic diet Mouse data, but still interesting https://t.co/0BbsqCLnyR

Dec 4, 2019 · 7 likes · 79,420 followers View post →
Thomas Weimbs, PhD
@weimbslab · X

This interview about Metabolism and Dietary Interventions in ADPKD has just been released. It is with a terrific group of academic nephrologists in Germany and Austria. The interview is in English. - Are ketones beneficial or detri…https://t.co/umGN9DFN5o https://t.co/oBveHP6n8I

Sep 9, 2022 · 6 likes · 3 shares · 1,656 followers View post →
Shaun Scott
@upyrbike · X

@weimbslab Congratulations! Nice work - enjoyed your interview with @MarcusSaemann https://t.co/TnicT5ECxo

Nov 4, 2022 · 6 likes · 1,436 followers View post →

All mentions

Terry Polevoy, MD
@TerryPolevoy · X

@sayerjigmi @dr_ericberg @RobertKennedyJr @G_W_Forum This Eric Berg is a chiropractor. Is he really that scary? https://t.co/U90LsBYgxd

May 16, 2025 · 1,704 followers View post →
Mary Johanna
@MaryJohanna6 · X

@MetabolicFactor Aren't you the YouTube Dr.Berg, Scientology connected in the US? https://t.co/ZwOAng7NkK

May 8, 2025 · 1,133 followers View post →
markusathome
@markusathome.bsky.social · Bluesky

Some webinars on Markus@Home on the topic of ADPKD: ADPKD - Metabolism and Dietary Inteventions youtu.be/ii1KSzvQphE?... in german language: KETO-ADPKD: youtu.be/ef0l6alNruQ?... Diagnostik & Therapie 2022 youtu.be/LU5bgJdlTrQ?...

Mar 26, 2025 View post →
markusathome
@MarkusAtHome · X

Some webinars on Markus@Home on the topic of ADPKD: ADPKD - Metabolism and Dietary Inteventions https://t.co/CAntd0Hf1Y in

Mar 26, 2025 · 2 likes · 118 followers View post →
Margaret Frey @margaretfrey.bsky.soc
@OneMargaretx · X

Scientologist Eric Berg Newest Advisor for RFK JR. The Scariest "Doctor" on YouTube (Eric Berg) https://t.co/32hclqctOC via @YouTube

Feb 16, 2025 · 2,917 followers View post →
Carnivore is Vegan
@CarnivoreIs · X

@_SupportAnimals @JustinTemplerSr @Voteblue4boogs @hvfreerangefarm @FarmsGarland @diamondback_xx Reversal of kidney failure from a ketogenic diet. https://t.co/WBcQ3VJm8F

Apr 10, 2024 · 3,692 followers View post →
Thomas Weimbs, PhD
@weimbslab · X

RT @gunnar_heine: @HeerspinkHiddo @DavidCWheeler2 @EWijkmark @MagnusAstrand @GreaserPete @BradRovin @IgAN_JBarratt @Dan_Fuster @inselgruppe…

Dec 23, 2023 · 1 share · 1,656 followers View post →
Gunnar Henrik Heine
@gunnar_heine · X

@HeerspinkHiddo @DavidCWheeler2 @EWijkmark @MagnusAstrand @GreaserPete @BradRovin @IgAN_JBarratt @Dan_Fuster @inselgruppe @unibern 2: KETO-ADPKD from @sadrijacukoski @weimbslab @MuellerRom and others 2022 Talks with @MuellerRom at https://t.co/3bS1Yjs3K0 (

Dec 22, 2023 · 4 likes · 1 share · 2,406 followers View post →
Shaun Scott
@upyrbike · X

@weimbslab Congratulations! Nice work - enjoyed your interview with @MarcusSaemann https://t.co/TnicT5ECxo

Nov 4, 2022 · 6 likes · 1,436 followers View post →
Dr. Ann
@AnnChildersMD · X

@DrDeborahMD @DoctorTro In mice: https://t.co/ayrZ5xNC0c

Oct 14, 2022 · 1 like · 13,855 followers View post →
SFNDT
@com_SFNDT · X

A l'occasion du "PKD awareness day", la SFNDT vous propose avec son homologue allemande DGfN, l'accès à une conférence intitulée "ADPKD - Metabolism and Dietary" avec le Pr Thomas Weimbs, de Santa Barbara ▶️https://t.co/MyOAHECN2M

Sep 13, 2022 · 1 like · 2,635 followers View post →
Florian Custodis
@floriancustodis · X

RT @gunnar_heine: Join us for your discussion on novel strategies for ADPKD - Focussing upon Metabolism and Dietary Interventions @weimbsla…

Sep 10, 2022 · 2 shares · 747 followers View post →
Thomas Weimbs, PhD
@weimbslab · X

This interview about Metabolism and Dietary Interventions in ADPKD has just been released. It is with a terrific group of academic nephrologists in Germany and Austria. The interview is in English. - Are ketones beneficial or detri…https://t.co/umGN9DFN5o https://t.co/oBveHP6n8I

Sep 9, 2022 · 6 likes · 3 shares · 1,656 followers View post →
marcus_saemann
@MarcusSaemann · X

RT @gunnar_heine: Join us for your discussion on novel strategies for ADPKD - Focussing upon Metabolism and Dietary Interventions @weimbsla…

Sep 9, 2022 · 2 shares · 666 followers View post →
Gunnar Henrik Heine
@gunnar_heine · X

Join us for your discussion on novel strategies for ADPKD - Focussing upon Metabolism and Dietary Interventions @weimbslab @MuellerRom @MarcusSaemann @com_SFNDT @oegnephro @dgfn_ev Santa Barbara https://t.co/KkrvD97UaR via @YouTube

Sep 9, 2022 · 3 likes · 2 shares · 2,406 followers View post →
marcus_saemann
@MarcusSaemann · X

Can diet impact a genetic disease?ADPKD - Metabolism and Dietary Interventions (Thomas Weimbs, Santa Barba... https://t.co/2HMYsPsHXx via @YouTube

Sep 9, 2022 · 3 likes · 1 share · 666 followers View post →
California high desert preacher.
@high_preacher · X

https://t.co/MYT5npDRqa

Jul 13, 2022 · 26 followers View post →
Troy Wynn
@BurpeesCure · X

@aoswari @BiggestComeback Here you go https://t.co/303ebTMDhZ

Jul 24, 2021 · 1 like · 137 followers View post →
Gil Ogden
@gilogden · X

Reversal of Diabetic Nephropathy by a Ketogenic Diet https://t.co/rYbuq8EXGe

Oct 8, 2020 · 49 followers View post →
young buck
@Alactricity · X

@bIondiewasabi @badboychadhoy I'm not keto, but can you cite something for this kidney/liver damage claim? All I found was research showing no change or in one study, positive impact: https://t.co/dSSvxea43D

May 26, 2020 · 440 followers View post →
C's not here
@expohjan · X

RT @type1tiger: This study had a huge impact on my decision to go low carb #T1D Reversal of Diabetic Nephropathy by a Ketogenic Diet http:…

Apr 22, 2020 · 2 shares · 61 followers View post →
OptimOZ.com.au
@OptimOZ · X

Reversal of Diabetic Nephropathy by a Ketogenic Diet (in mice) https://t.co/JgzeitYFty @JasonMastaitis https://t.co/NlTcyPAs8g https://t.co/QHTTzHFzJk

Dec 23, 2019 · 471 followers View post →
Sundance65
@Sundancekid65 · X

RT @RDValerie: We need to start referencing these studies, and not just cherry-picking research that is not aligned with physiology: Revers…

Dec 5, 2019 · 2 shares · 275 followers View post →
Valerie, RD, MPH
@RDValerie · X

We need to start referencing these studies, and not just cherry-picking research that is not aligned with physiology: Reversal of Diabetic Nephropathy by a Ketogenic Diet. Sad thing is, show people this, they will still deny and cite dangers of keto. https://t.co/ZPKsszXR97

Dec 4, 2019 · 12 likes · 2 shares · 33,962 followers View post →
JT | Jerry Teixeira
@jerryteixeira · X

@RDValerie https://t.co/0BbsqCLnyR

Dec 4, 2019 · 9 likes · 79,420 followers View post →
JT | Jerry Teixeira
@jerryteixeira · X

@JoseAntonioPhD @DrHorwitz @DeanOrnishMD @mackinprof OP forgets to mention in his tweet that the studies are talking about those who may already have kidney issues due to diabetes. Also here is a study showing reversal of Diabetic Nephropathy with a ketogenic diet Mouse data, but still interesting https://t.co/0BbsqCLnyR

Dec 4, 2019 · 7 likes · 79,420 followers View post →
Shashi Iyengar | Metabolic Health India®
@shashiiyengar · X

RT @gerdosi: @su_js1 @ProfTimNoakes I bet that’s based on this 2011 study? https://t.co/xVS2JaiWxv

Oct 19, 2019 · 3 shares · 29,433 followers View post →
Sewe Saldanha
@SeweS_ · X

RT @gerdosi: @su_js1 @ProfTimNoakes I bet that’s based on this 2011 study? https://t.co/xVS2JaiWxv

Oct 19, 2019 · 3 shares · 20,803 followers View post →
Gabor Erdosi
@gerdosi · X

@su_js1 @ProfTimNoakes I bet that’s based on this 2011 study? https://t.co/xVS2JaiWxv

Oct 18, 2019 · 1 like · 3 shares · 25,861 followers View post →
Chriss Torres
@ChrissTFx · X

RT @DeMetabolismo:

Aug 3, 2019 · 1 share · 71 followers View post →
Mauricio Silva
@DeMetabolismo · X

Aug 3, 2019 · 3 likes · 1 share · 2,519 followers View post →
Ketogenic Diet
@KetoDietDaily · X

Reversal of Diabetic Nephropathy by a Ketogenic Diet https://t.co/uWVGgfWVJz

Jul 19, 2019 · 1 like · 11,856 followers View post →
Julian Skinner
@julestw9 · X

RT @Travis_Statham: https://t.co/s8MNbI6GMd ‘Reversal of Diabetic Nephropathy by a Ketogenic Diet’ This infuriates me. RD gets 15 minutes…

Jul 18, 2019 · 3 shares · 2,794 followers View post →
KetoScience
@KetoScience · X

Diabetic nephropathy was allowed to develop, then half the mice were switched to a ketogenic diet. After 8 weeks it was completely reversed. #diabetes #keto #science https://t.co/zmsYy62ydh

Jun 22, 2019 · 3 likes · 669 followers View post →
Julian Skinner
@julestw9 · X

RT @Travis_Statham: https://t.co/s8MNbI6GMd ‘Reversal of Diabetic Nephropathy by a Ketogenic Diet’ This infuriates me. RD gets 15 minutes…

Jun 15, 2019 · 3 shares · 2,794 followers View post →
ZKA
@0knowledgeactor · X

RT @Travis_Statham: https://t.co/s8MNbI6GMd ‘Reversal of Diabetic Nephropathy by a Ketogenic Diet’ This infuriates me. RD gets 15 minutes…

Jun 14, 2019 · 3 shares · 1,174 followers View post →
Travis Statham
@Travis_Statham · X

https://t.co/s8MNbI6GMd ‘Reversal of Diabetic Nephropathy by a Ketogenic Diet’ This infuriates me. RD gets 15 minutes more time for patient on dialysis. #Ketogenic diet reverses DN In 2 months. #Dietitians are not even heroes. They are frauds. https://t.co/vzPFU27tTa

Jun 14, 2019 · 11 likes · 3 shares · 12,696 followers View post →
David Wyant
@wyadvd · X

Reversal of Diabetic Nephropathy by a Ketogenic Diet https://t.co/ZZPU9QmDT0

May 4, 2019 · 2,694 followers View post →
KetoScience
@KetoScience · X

Diabetic nephropathy was allowed to develop, then half the mice were switched to a ketogenic diet. After 8 weeks it was completely reversed. #organs #keto #science https://t.co/88eB28wESl

May 2, 2019 · 2 likes · 669 followers View post →
QuinGem
@quingem · X

RT @KetoScience: Diabetic nephropathy was allowed to develop, then half the mice were switched to a ketogenic diet. After 8 weeks it was co…

Apr 14, 2019 · 3 shares · 459 followers View post →
eleanorina
@_eleanorina · X

RT @KetoScience: Diabetic nephropathy was allowed to develop, then half the mice were switched to a ketogenic diet. After 8 weeks it was co…

Apr 14, 2019 · 3 shares · 3,188 followers View post →
Steve Cooksey
@diabeteswarrior · X

RT @KetoScience: Diabetic nephropathy was allowed to develop, then half the mice were switched to a ketogenic diet. After 8 weeks it was co…

Apr 14, 2019 · 3 shares · 7,718 followers View post →
C.R.S.
@IndependentText · X

RT @KetoScience: Diabetic nephropathy was allowed to develop, then half the mice were switched to a ketogenic diet. After 8 weeks it was co…

Apr 14, 2019 · 3 shares · 306 followers View post →
KetoScience
@KetoScience · X

Diabetic nephropathy was allowed to develop, then half the mice were switched to a ketogenic diet. After 8 weeks it was completely reversed. #diabetes #keto #science https://t.co/zmsYy62ydh

Apr 14, 2019 · 5 likes · 3 shares · 669 followers View post →