"The preponderance of evidence [suggests] biological response to weight loss involves comprehensive, persistent, and redundant adaptations in energy homeostasis and that these adaptations underlie the high recidivism rate in obesity therapeutics." https://t.co/djZV2HPAST
Biology's response to dieting: the impetus for weight regain.
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Jan 2018 – Oct 2025Where it's discussed
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Facebook24 posts
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X / Twitter23 posts
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YouTube14 videos
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What people are saying
The group consistently emphasizes that weight regain is driven by biological responses, with posts like 'the biological response involves comprehensive, persistent adaptations' and personal stories revealing struggles with sustaining weight loss. The tone combines scientific references and personal reflection, which underscores the widespread recognition of the complexity of long-term weight management.
Most discussion participants acknowledge and support the scientific consensus that biological responses complicate long-term weight loss.
Posts demonstrate a high level of curiosity, with many referencing detailed physiological and psychological factors and sharing personal stories.
Many contributions include retweets, references to studies, comparisons with personal experiences, and nuanced discussions about metabolic and emotional factors.
The discussions highlight an awareness of the biological challenges surrounding weight management, which could influence public perceptions and future research focus.
Abstract in brief
- Dieting is the most common method for weight loss among obese individuals, but it often leads to weight regain, highlighting the challenges in achieving long-term success.
- The review discusses the biological factors that contribute to weight regain, including adaptations that occur with energy-restricted diets and how these impact energy balance.
- It suggests that effective long-term weight loss strategies must be as comprehensive and persistent as the biological adaptations that lead to weight regain.
Top posts
Most liked on X and Bluesky@realpeteyb123 Medication, health conditions, struggling to exercise, lack of low calorie nutritious food etc. Even without these factors, they're unlikely to keep the weight off. https://t.co/m86fPTmcOK
1/6 ¿Por qué es tan difícil mantener el peso después de una dieta?
Biology's response to dieting: the impetus for weight regain https://t.co/mY6GjXd0kh
@PrimeDP10 @DoubleDeezze Sigh. More trollishness from a person who would impose his personal experience (and his internalized fat-phobia) upon others. He ought to do some reading: https://t.co/i0vehBqZxK
Así es: el reto no es solo bajar peso, sino luego no recuperar esa pérdida. Incluso personas con sobrepeso 1º pierden kilos con relativa facilidad, pero 1 año después del adelgazamiento, el 80% vuelve al peso inicial. (2 años después el 85%, y 3 el 95%) https://t.co/lCcjEtM2DS
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1/6 ¿Por qué es tan difícil mantener el peso después de una dieta?
https://t.co/o1eO4Re0aD
RT @punished3liza: "The preponderance of evidence [suggests] biological response to weight loss involves comprehensive, persistent, and red…
RT @punished3liza: "The preponderance of evidence [suggests] biological response to weight loss involves comprehensive, persistent, and red…
RT @punished3liza: "The preponderance of evidence [suggests] biological response to weight loss involves comprehensive, persistent, and red…
"The preponderance of evidence [suggests] biological response to weight loss involves comprehensive, persistent, and redundant adaptations in energy homeostasis and that these adaptations underlie the high recidivism rate in obesity therapeutics." https://t.co/djZV2HPAST
What contributes to our bodies energy needs
@realpeteyb123 Medication, health conditions, struggling to exercise, lack of low calorie nutritious food etc. Even without these factors, they're unlikely to keep the weight off. https://t.co/m86fPTmcOK
Así es: el reto no es solo bajar peso, sino luego no recuperar esa pérdida. Incluso personas con sobrepeso 1º pierden kilos con relativa facilidad, pero 1 año después del adelgazamiento, el 80% vuelve al peso inicial. (2 años después el 85%, y 3 el 95%) https://t.co/lCcjEtM2DS
Biology's response to dieting: the impetus for weight regain https://t.co/mY6GjXd0kh
Great piece from the Huberman podcast, with several cool insights: The Science of Eating for Health https://t.co/qoQU9htwuw paper links in video description. A key one https://t.co/VpbifdQUX9
You will regain some of the weight you lost. This is just the reality of weight loss. Your body doesn't want to lose weight. https://t.co/aItWtcCOhf
RT @doctordiego1: El problema no es perder peso. El problema es mantenerlo. https://t.co/Lk9vSUveKB
El problema no es perder peso. El problema es mantenerlo. https://t.co/Lk9vSUveKB
@Christo63100802 @Tony_Furniere U weet het dus beter dan wat wetenschappelijke studies al jaren aantonen? https://t.co/CkfD3uqjmJ https://t.co/lnwazdMaDD https://t.co/m2T0DgYrga https://t.co/KHhPCpCXwt
RT @dr_kevinlee: @KurtLass1 https://t.co/9XAzXSLoQy
@KurtLass1 https://t.co/9XAzXSLoQy
@FloralDesignsF1 @thefatdoctoruk @BioLayne I listened to a podcast way back by Layne. He cited a paper https://t.co/AYGw0mvAe6 & he’s is no doubt about the metabolic challenges. The psych/embodied/social are omitted but still, nutritionists have insight into the endpoints.
D'autant plus qu'une forte perte de poids entraîne des changements métaboliques favorisant la reprise de poids et l'apparition de comportements boulimiques. https://t.co/xtv5lJkBh3 #TCA https://t.co/Ont6w81ui8
@PrimeDP10 @DoubleDeezze Sigh. More trollishness from a person who would impose his personal experience (and his internalized fat-phobia) upon others. He ought to do some reading: https://t.co/i0vehBqZxK
Biology's response to dieting: the impetus for weight regain. https://t.co/kL9X8Gfwr7
Biology's response to dieting: the impetus for weight regain | American Journal of Physiology-Regulatory, Integrative and Comparative Physiology https://t.co/M1zWQsdpxk
@monicakriete You’ve probably also seen this one. As a fat boy I was put on my first (non-consensual) diet at age 11. It made me fatter. Subsequent weight-loss attempts, resulting from my internalization of the oppression, had the same effect.. https://t.co/i0vehBqZxK https://t.co/nFH5jXudsM
A