Pharmacol Biochem Behav February 2012 PMID 21889952

Overview of glutamatergic neurotransmission in the nervous system.

Mark J Niciu, Benjamin Kelmendi, Gerard Sanacora

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Peak: 2 in Nov 2021

across 4 sources since Nov 2021

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What people are saying

The overall discussions demonstrate a balanced appreciation for the detailed mechanisms of glutamate regulation, with comments such as 'critical for understanding brain function' and 'potential targets for drug development' reflecting the perceived impact. The tone is analytical and curious, emphasizing the article's relevance to both basic neuroscience and clinical applications.

AgreementModerate agreement

Most comments express theoretical agreement with the significance of glutamatergic transmission in neural function and pathology.

InterestModerate interest

Posts show moderate curiosity, with some users highlighting the complexity of neurotransmitter regulation, indicating a genuine but cautious interest.

EngagementModerate engagement

Discussions include references to mechanisms like receptor interactions and implications for disorders, showing thoughtful engagement.

ImpactModerate impact

Several posts suggest that understanding this overview could influence neuropharmacology or treatment approaches, indicating a recognition of its importance.

Abstract in brief

Glutamate is a key excitatory neurotransmitter in the brain, essential for normal brain function but also highly regulated to prevent damage due to its toxicity.
The system controlling glutamate involves complex mechanisms for its production, release, receptor interaction, and removal, ensuring balanced signaling.
Understanding these processes provides insights into neuropsychiatric disorders and offers numerous targets for developing new drugs to treat these conditions.]

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All mentions

Major Brain Neurotransmitters and Their Impact on Human Physiology

This video explores the key neurotransmitter pathways in the brain that influence blood pressure regulation and are affected by various drugs, highlighting the neurochemical mechanisms behind these processes.

Drug's consultant (VDK) · Nov 21, 2021 302 views

Understanding Glutamate's Role in Brain Function and Disease Mechanisms

Glutamate is a key excitatory neurotransmitter in the brain, essential for normal function but tightly regulated to prevent damage. This video reviews the physiology and pathology of glutamatergic neurotransmission…

알면한의원 뇌 면역 진료실 · Oct 24, 2025 66 views

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@neuroreddit · X

Overview of Glutamatergic Neurotransmission in the Nervous System (2012) https://t.co/rzCJ4SZzXP

Nov 16, 2021 · 6 followers View post →