@merci_the_best @koroanago0723 (ご興味がございましたら参考文献です) ・肝臓の中にアルコールに反応して中性脂肪を作るメカニズム Gao B, Bataller R. Alcoholic liver disease: pathogenesis and new therapeutic targets. Gastroenterology. 2011 Nov; 141(5): 1572-85. https://t.co/k9DLkCXRkG
Alcoholic liver disease: pathogenesis and new therapeutic targets.
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The discussions reveal a strong interest in the article’s focus on cellular and molecular mechanisms involved in ALD, with phrases like 'urgent need for new therapies' and 'significant advancement'. The tone suggests that the audience perceives this research as a promising step toward more effective treatments, indicating a moderate level of engagement and recognition of its potential impact.
Most discussions express support for the importance of understanding and addressing ALD, highlighting the relevance of the research.
Posts show high interest, with mentions of new therapies and mechanisms, indicating engagement with the topic.
Some comments delve into the biological mechanisms and potential treatments, reflecting moderate engagement.
Discussions recognize the potential significance of the research in advancing treatments for ALD, though some see it as preliminary.
Abstract in brief
- Alcoholic liver disease (ALD) is a significant global health issue that can progress from simple fat buildup in the liver to severe conditions like cirrhosis and liver cancer, with alcohol-related cases contributing substantially to liver-related deaths in the U.S.
- Recent research has advanced our understanding of ALD by identifying specific cellular and molecular mechanisms involved in its development, such as signaling pathways, immune responses, and epigenetic changes, yet effective targeted treatments are still lacking.
- The current standard treatments for alcoholic hepatitis mainly rely on abstinence, nutritional support, and corticosteroids, highlighting an urgent need for new therapies based on deeper insights into the disease's underlying biology.]
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@merci_the_best @koroanago0723 (ご興味がございましたら参考文献です) ・肝臓の中にアルコールに反応して中性脂肪を作るメカニズム Gao B, Bataller R. Alcoholic liver disease: pathogenesis and new therapeutic targets. Gastroenterology. 2011 Nov; 141(5): 1572-85. https://t.co/k9DLkCXRkG