Participants generally agree that the study provides evidence linking lower protein intake with increased calorie consumption, especially from snacks, and they actively discuss its implications for dietary guidelines and obesity prevention. The tone varies from curiosity to analytical, with mention of specific research findings, study support, and questions about practical applications, reflecting meaningful engagement and recognition of its potential impact.
AgreementModerate agreement
Most discussions support the idea that protein levels influence overeating, with many referencing studies showing increased calorie intake when dietary protein is diluted.
InterestHigh interest
The discussions demonstrate high curiosity about the implications of the research, with many seeking further understanding of the protein leverage hypothesis and its relevance to obesity.
EngagementHigh engagement
Participants engage deeply by referencing specific studies, questioning the effects in various contexts, and analyzing the data, indicating active and thoughtful involvement.
ImpactModerate impact
The conversations recognize the research's potential to influence nutritional strategies and obesity interventions, though some acknowledge limitations in the magnitude of effects observed.
Abstract in brief
The study tested the protein leverage hypothesis, which suggests that a strong desire for protein may lead to increased overall energy intake and possibly obesity, by providing lean humans with diets of varying protein levels.
Results showed that reducing dietary protein from 15% to 10% led to increased total energy intake, mainly from snacks, but did not fully maintain protein intake, indicating that protein leverage is only partial; increasing protein to 25% did not change energy intake.
Participants reported feeling hungrier after eating lower-protein meals, especially several hours later, which implies that diluting dietary protein with other macronutrients encourages overeating, potentially raising obesity risk.]
Nov 12, 2022 · 194 likes · 41 shares · 27,600 followersView post →
JH
Jason Helmes
@anymanfitness · X
The “Protein Leverage Hypothesis” is an interesting idea that’s gaining some traction in the nutritional science community.
It postulates humans need a certain threshold of protein, and will continually eat until that threshold is achieved.
https://t.co/r2DY8Pabpt
Nov 21, 2022 · 59 likes · 4 shares · 84,226 followersView post →
エE
エボサイ(EvoPsy)
@selfcomestomine · X
Testing Protein Leverage in Lean Humans: A Randomised Controlled Experimental Study https://t.co/RBZfmIXjq3 食事におけるタンパク質の比率の低下により「タンパク質用の食欲」が満たされず、過剰なエネルギー摂取が促進される。実際にタンパク質摂取比率を減らした被験者は空腹感スコアが上昇。
May 26, 2020 · 36 likes · 19 shares · 30,737 followersView post →
PS
Prof David Raubenheimer & Prof Stephen Simpson
@eatlikeanimals · X
@DikemanDave @AmDiabetesAssn @tednaiman Here's the evidence. Low protein subjects ate more energy largely through snacking between meals
https://t.co/okm8pljzZM https://t.co/HyK1XSr2vL
@KieranO No, that protein leverage/appetite effect appears to stop at around 15% of energy intake. https://t.co/xHxjjvEx0V
People have talked about this for years, and I do think protein is the most satiating nutrient, but even that is a small effect.
Oct 27, 2023 · 15 likes · 3 shares · 56,035 followersView post →
KH
Kevin Hall
@KevinH_PhD · X
@tednaiman @martykendall2 Am I reading this graph correctly that a 30% versus 10% protein diet should result in ~1000 kcal/d difference in energy intake? This appears unsupported by human trials showing much smaller effect sizes:
https://t.co/WewWtGb56J
https://t.co/48DXApnSPR
https://t.co/EI2jph0x49
Discover the effectiveness of protein shakes in weight loss and muscle growth. Dr. Julia Fischer explores what’s in these supplements, the differences between whey and plant protein, and discusses the implications of…
This study examined how normal vs high-protein breakfasts affect food cravings and dopamine signals in overweight teenage girls. Eating breakfast decreased cravings and increased dopamine activity, with high-protein…
Protein Leverage Hypothesis,
Lowering the percent protein of the diet
from 15% to 10% resulted in higher total energy intake, predominantly from savoury-flavoured foods available between meals.
https://t.co/6swfl7WkBV.
May 21, 2024 · 1 like · 5,061 followersView post →
RT @ErrXmind: @JohnnyCarthief @ProfTimNoakes "In our study population a change in the nutritional environment that dilutes dietary protein…
Dec 16, 2023 · 4 shares · 227 followersView post →
GM
George Macharia
@machariageorg · X
RT @ErrXmind: @JohnnyCarthief @ProfTimNoakes "In our study population a change in the nutritional environment that dilutes dietary protein…
Dec 16, 2023 · 4 shares · 157 followersView post →
TN
Tim Noakes
@ProfTimNoakes · X
RT @ErrXmind: @JohnnyCarthief @ProfTimNoakes "In our study population a change in the nutritional environment that dilutes dietary protein…
Dec 16, 2023 · 4 shares · 157,807 followersView post →
EM
Erick Minor
@ErrXmind · X
@JohnnyCarthief @ProfTimNoakes "In our study population a change in the nutritional environment that dilutes dietary protein with carbohydrate and fat promotes overconsumption, enhancing the risk for potential weight gain."
https://t.co/tyJkbwdNkT
Dec 16, 2023 · 5 likes · 4 shares · 360 followersView post →
G
GRUNY ®️
@GRUNY_ENERGY · X
Protein Leverage Hypothesis
Studies show the more protein you chomp down the less likely you are to gain fat.
Why? Your body “prefers and prioritizes” protein, hence once you meet the required amount you are less likely to have cravings.
https://t.co/9RRuQoMogC
RT @mackinprof: @KieranO No, that protein leverage/appetite effect appears to stop at around 15% of energy intake. https://t.co/xHxjjvEx0V…
Oct 29, 2023 · 3 shares · 1,070 followersView post →
W
:wq
@edxe47 · X
RT @mackinprof: @KieranO No, that protein leverage/appetite effect appears to stop at around 15% of energy intake. https://t.co/xHxjjvEx0V…
Oct 27, 2023 · 3 shares · 128 followersView post →
SB
Simon Hill MSc, BSc
@theproof · X
RT @mackinprof: @KieranO No, that protein leverage/appetite effect appears to stop at around 15% of energy intake. https://t.co/xHxjjvEx0V…
Oct 27, 2023 · 3 shares · 34,367 followersView post →
SH
Stuart Phillips (he/him)
@mackinprof · X
@KieranO No, that protein leverage/appetite effect appears to stop at around 15% of energy intake. https://t.co/xHxjjvEx0V
People have talked about this for years, and I do think protein is the most satiating nutrient, but even that is a small effect.
Oct 27, 2023 · 15 likes · 3 shares · 56,035 followersView post →
S
Sudās
@sudas1891 · X
@CarnivoreAugust @tednaiman https://t.co/ULVOM6VzhY this study? 10,15,25 percent protein? “Although total energy intake during the 15% and 25% protein periods did not differ”
Mar 21, 2023 · 3 likes · 1,793 followersView post →
D
Das
@ssdas29 · X
@robertlufkinmd I think Gary Taubes was talking about protein leverage hypothesis ? or was he talking about hyperpalatable carbs
Testing protein leverage in lean humans: a randomised controlled experimental study
https://t.co/qDO2usU6d4
@DrEenfeldt @KevinH_PhD Our work suggests protein leverage is a longer-term effect, influencing satiety (fullness between meals - e.g., likelihood of snacking) not satiation (size of the meal): https://t.co/okm8plBJdU As also seen in @KevinH_PhD – constant daily protein intake over 14 days https://t.co/c3Tezkb9pD
Feb 1, 2023 · 10 likes · 3,272 followersView post →
DT
dick taylor
@dick__taylor · X
@PlantChompers @KevinH_PhD Kevin, I enjoyed your paper. I know it wasn't within the scope of your research, but what do you think of the protein leverage theory of obesity? It never seems to get much coverage.
https://t.co/fwkSriZgWa
RT @anymanfitness: The “Protein Leverage Hypothesis” is an interesting idea that’s gaining some traction in the nutritional science communi…
Nov 22, 2022 · 4 shares · 248 followersView post →
CW
Classless Warfare
@VerbalTrebuchet · X
RT @anymanfitness: The “Protein Leverage Hypothesis” is an interesting idea that’s gaining some traction in the nutritional science communi…
Nov 22, 2022 · 4 shares · 355 followersView post →
A
AJAC
@AJA_Cortes · X
RT @anymanfitness: The “Protein Leverage Hypothesis” is an interesting idea that’s gaining some traction in the nutritional science communi…
Nov 21, 2022 · 4 shares · 235,872 followersView post →
G
GJ
@johnstontalk · X
RT @anymanfitness: The “Protein Leverage Hypothesis” is an interesting idea that’s gaining some traction in the nutritional science communi…
Nov 21, 2022 · 4 shares · 2,013 followersView post →
JH
Jason Helmes
@anymanfitness · X
The “Protein Leverage Hypothesis” is an interesting idea that’s gaining some traction in the nutritional science community.
It postulates humans need a certain threshold of protein, and will continually eat until that threshold is achieved.
https://t.co/r2DY8Pabpt
Nov 21, 2022 · 59 likes · 4 shares · 84,226 followersView post →
Nov 12, 2022 · 194 likes · 41 shares · 27,600 followersView post →
D
Das
@ssdas29 · X
@lipo_fan @CommunistoObama @drmohanv Testing protein leverage in lean humans: a randomised controlled experimental study
https://t.co/8KF90Im5WU
I think ALL CKD patients on a phosphorous restricted diet should be fed a minimum of this protein
Contemplating this over the last few days. Currently undecided.
From the protein leverage data, we know that there is a dead zone between 15%-25%--variations within the moderate range for protein don't do much. https://t.co/XPIru6M1yI https://t.co/2CtENDHCcx
@EcoPaulPeace @DesjardinsCat I have seen bags of research on diabetes. It is essential eating excess carbohydrates. Appetite is driven by our need for protein. Low protein foods drive overeating.
https://t.co/jo4cOEHVGv
@fmahmad88 @luis_villasenor @tednaiman @winfinancial @comebackking1 @screenack @BiggestComeback ..effect. The protein leverage study didn't show an effect of energy intake at meals, but did show a difference in between meal snacking...
https://t.co/XPIru6M1yI
@tednaiman @martykendall2 Am I reading this graph correctly that a 30% versus 10% protein diet should result in ~1000 kcal/d difference in energy intake? This appears unsupported by human trials showing much smaller effect sizes:
https://t.co/WewWtGb56J
https://t.co/48DXApnSPR
https://t.co/EI2jph0x49
@tednaiman 1. The effect of protein on satiety is complicated- some studies suggest for most people above about 15% energy or ~1.2g/kg protein has a no effect on satiety/ total energy consumption https://t.co/6OB00NitlJ
https://t.co/v0k1a7avye
RT @selfcomestomine: Testing Protein Leverage in Lean Humans: A Randomised Controlled Experimental Study https://t.co/RBZfmIXjq3 食事におけるタンパク…
Mar 4, 2021 · 19 shares · 213 followersView post →
赤
赤点急降下
@twrdtw · X
RT @selfcomestomine: Testing Protein Leverage in Lean Humans: A Randomised Controlled Experimental Study https://t.co/RBZfmIXjq3 食事におけるタンパク…
Mar 3, 2021 · 19 shares · 1,285 followersView post →
IK
Italian Goes Keto
@toprate222 · X
RT @Mangan150: @p70S6K @ahhite Also there's an RCT of protein leverage in humans, hypothesis was supported https://t.co/Yvqef7j2kQ
Feb 7, 2021 · 1 share · 1,191 followersView post →
PM
P.D. Mangan Health & Freedom Maximalist
@Mangan150 · X
@p70S6K @ahhite Also there's an RCT of protein leverage in humans, hypothesis was supported https://t.co/Yvqef7j2kQ
Feb 7, 2021 · 6 likes · 1 share · 297,794 followersView post →
SG
Samuele Graffiedi
@irongrafFT · X
Quando riduci la percentuale delle proteine (10% cal totali, rispetto a 15% e 25%), cioè “diluisci” le proteine con carboidrati e grassi, tendi a mangiare di più, soprattutto snack palatabili, perché hai più fame fuori pasto.
https://t.co/hhLrVgyDIj https://t.co/DcNFNEdq7r
Nov 29, 2020 · 3 likes · 1,074 followersView post →
Kプ
KOJI@プライマルコーチ
@kojija · X
【プロティンレバレッジ仮説 (PLH )】
Y: F+C
X: P
https://t.co/VSG6acZaSd https://t.co/JnxxMPxCR0
Nov 11, 2020 · 3 likes · 2,312 followersView post →
RT @selfcomestomine: Testing Protein Leverage in Lean Humans: A Randomised Controlled Experimental Study https://t.co/RBZfmIXjq3 食事におけるタンパク…
May 26, 2020 · 19 shares · 733 followersView post →
KE
KlahaMidras@FF14 Atomos Ele
@Klaha_Mid · X
RT @selfcomestomine: Testing Protein Leverage in Lean Humans: A Randomised Controlled Experimental Study https://t.co/RBZfmIXjq3 食事におけるタンパク…
May 26, 2020 · 19 shares · 844 followersView post →
株恋
株式会社GEOJACKASS代表取締役社長@踊る君を見て,恋が始まって
@geojackass · X
RT @selfcomestomine: Testing Protein Leverage in Lean Humans: A Randomised Controlled Experimental Study https://t.co/RBZfmIXjq3 食事におけるタンパク…
May 26, 2020 · 19 shares · 495 followersView post →
ピ虞
ピンキリパイと化したぐほん(虞翻)
@trd_lysenko · X
RT @selfcomestomine: Testing Protein Leverage in Lean Humans: A Randomised Controlled Experimental Study https://t.co/RBZfmIXjq3 食事におけるタンパク…
May 26, 2020 · 19 shares · 899 followersView post →
M駄
mOxOn(駄文生成装置)
@MOX_ON · X
RT @selfcomestomine: Testing Protein Leverage in Lean Humans: A Randomised Controlled Experimental Study https://t.co/RBZfmIXjq3 食事におけるタンパク…
May 26, 2020 · 19 shares · 242 followersView post →
偽B
偽トノイケ☆ダイスケ@BIとJGPクラスタ捜査中
@gannbattemasenn · X
RT @selfcomestomine: Testing Protein Leverage in Lean Humans: A Randomised Controlled Experimental Study https://t.co/RBZfmIXjq3 食事におけるタンパク…
May 26, 2020 · 19 shares · 1,482 followersView post →
E
emanyon
@emanyon · X
RT @selfcomestomine: Testing Protein Leverage in Lean Humans: A Randomised Controlled Experimental Study https://t.co/RBZfmIXjq3 食事におけるタンパク…
May 26, 2020 · 19 shares · 1,039 followersView post →
TD
tutor desu
@sakanujin · X
RT @selfcomestomine: Testing Protein Leverage in Lean Humans: A Randomised Controlled Experimental Study https://t.co/RBZfmIXjq3 食事におけるタンパク…
May 26, 2020 · 19 shares · 1,362 followersView post →
F
fukanju
@fukanju · X
RT @selfcomestomine: Testing Protein Leverage in Lean Humans: A Randomised Controlled Experimental Study https://t.co/RBZfmIXjq3 食事におけるタンパク…
May 26, 2020 · 19 shares · 4,358 followersView post →
り
りれきち
@rire · X
RT @selfcomestomine: Testing Protein Leverage in Lean Humans: A Randomised Controlled Experimental Study https://t.co/RBZfmIXjq3 食事におけるタンパク…
May 26, 2020 · 19 shares · 1,339 followersView post →
エE
エボサイ(EvoPsy)
@selfcomestomine · X
Testing Protein Leverage in Lean Humans: A Randomised Controlled Experimental Study https://t.co/RBZfmIXjq3 食事におけるタンパク質の比率の低下により「タンパク質用の食欲」が満たされず、過剰なエネルギー摂取が促進される。実際にタンパク質摂取比率を減らした被験者は空腹感スコアが上昇。
May 26, 2020 · 36 likes · 19 shares · 30,737 followersView post →
@DikemanDave @AmDiabetesAssn @tednaiman Here's the evidence. Low protein subjects ate more energy largely through snacking between meals
https://t.co/okm8pljzZM https://t.co/HyK1XSr2vL
The protein leverage hypothesis states that humans tend to eat a certain protein:fat/carb ratio and shifts this ratio by increasing energy intake.
Could increasing protein intake be the answer to the obesity epidemic?
https://t.co/UTxmUzHRFN https://t.co/ikrpZB9eyY
@CassandraCorvid @FatEmperor @tednaiman Compelling study that <15% protein will drive people to eat more total calories. But no difference between 15% and 25% protein https://t.co/HF0bFtbkvh
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