J Physiol January 2012 PMID 22106173

Muscle time under tension during resistance exercise stimulates differential muscle protein sub-fractional synthetic responses in men.

Nicholas A Burd, Richard J Andrews, Daniel W D West, Jonathan P Little, Andrew J R Cochran, Amy J Hector, Joshua G A Cashaback, Martin J Gibala, James R Potvin, Steven K Baker, Stuart M Phillips

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Mentions

97
Peak: 16 in Feb 2022
across 5 sources since Nov 2019

Extended reach

519,852
potential audience

Total likes

1,354

Video views

119,072

Mentions per month

Nov 2019 – Sep 2025

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AI synopsis

What people are saying

The discussions strongly support the study's conclusion that increasing muscle time under tension enhances muscle protein synthesis, with posts referencing specific results like ‘mitochondrial and sarcoplasmic protein synthesis increased by as much as 114% and 77%,’ demonstrating high engagement and perceived impact. The tone and choice of words, such as 'scientific explanation' and 'important determinants,' highlight a focus on evidence-based implications for training practices.

AgreementStrong agreement

Most discussions support the article's findings, emphasizing the importance of time under tension in muscle growth.

InterestHigh interest

The posts show high interest, with many highlighting the relevance of specific training strategies.

EngagementHigh engagement

Users actively analyze and summarize the study, referencing detailed aspects like protein synthesis and exercise volume.

ImpactHigh impact

Several discussions suggest the findings could influence training methods and scientific understanding of resistance exercise adaptations.

Abstract in brief

  • The study found that longer muscle time under tension during low intensity resistance exercise (6 seconds per rep) led to higher rates of muscle protein synthesis, particularly in mitochondrial, sarcoplasmic, and myofibrillar fractions, compared to shorter tension (1 second per rep).
  • This increased protein synthesis was linked to higher phosphorylation of anabolic signaling proteins like p70S6K and increased expression of PGC1, especially within the first 6 hours post-exercise, indicating enhanced muscle adaptation processes.
  • Overall, the results suggest that extending muscle tension duration during resistance exercises can boost muscle growth-related responses and improve recovery and adaptation even at low exercise intensities.]

Top posts

Most liked on X and Bluesky
P.D. Mangan Health & Freedom Maximalist
@Mangan150 · X

In weight training, longer time under tension and lifting to failure increases the rate of muscle protein synthesis. Lifting weights isn't, or shouldn't be, about moving a weight around, but effectively giving muscles the right growth stimulus. https://t.co/7clyK6FzaM

Feb 25, 2022 · 168 likes · 20 shares · 294,505 followers View post →
Dr Kpakpo
@DrKpakpoAcquaye · X

As you increase time under tension, especially peak tension, mitochondrial and sarcoplasmic protein synthesis are elevated by as much as by 114% and 77%, respectively.(https://t.co/zD7DAOWGZr).

Nov 9, 2022 · 10 likes · 5,862 followers View post →
Stuart Phillips (he/him)
@mackinprof · X

@Alan_Couzens @Fit_For_Golf @BradSchoenfeld When you allow people to work to fatigue, the fibre recruitment is the same regardless of load: https://t.co/t9asyxzjxR We've shown that TUT and volume modulate this response, but it's not a load-dependent outcome: https://t.co/v5sUoS1m0U https://t.co/67MgRBkv7s

Jul 30, 2023 · 8 likes · 56,047 followers View post →
john morley
@drjohnmorley · X

Muscle time under tension during resistance exercise stimulates differential muscle protein sub-fractional synthetic responses in men https://t.co/PbXRJgMXQH

Nov 11, 2019 · 5 likes · 2 shares · 8,305 followers View post →
加藤 光
@HK_hypertrophy · X

https://t.co/burtXPSQcO 裏付けがあった方がトレーニングは納得して追い込める

Mar 9, 2023 · 5 likes · 1,668 followers View post →
WEBさん@一日一筋
@WebMuscler · X

大胸筋の厚みが欲しいならこの5つを絶対意識せよ! 最強の腕立て伏せ筋トレメニューを科学的に徹底解説! https://t.co/nTlgQJEAoA https://t.co/x1jKPEWJEa

Aug 26, 2023 · 5 likes · 129 followers View post →

All mentions

ナニカグループ常任理事
@uisgdi · X

大胸筋の厚みが欲しいならこの5つを絶対意識せよ!最強の腕立て伏せ筋トレメニューを科学的に徹底解説! https://t.co/hJsfCq3f4F via @YouTube

Aug 29, 2023 · 1,271 followers View post →
甲楽わん@かのかり沼
@korakuone_shu · X

ふーん

Aug 28, 2023 · 2 likes · 984 followers View post →
WEBさん@一日一筋
@WebMuscler · X

大胸筋の厚みが欲しいならこの5つを絶対意識せよ! 最強の腕立て伏せ筋トレメニューを科学的に徹底解説! https://t.co/nTlgQJEAoA https://t.co/x1jKPEWJEa

Aug 26, 2023 · 5 likes · 129 followers View post →
しなやかな舞―ええ塩梅―
@tM1CYeKo3FZsV8S · X

大胸筋の厚みが欲しいならこの5つを絶対意識せよ!最強の腕立て伏せ筋トレメニューを科学的に徹底解説! https://t.co/KY2Tt3NZrr @YouTubeより

Aug 26, 2023 · 1 like · 824 followers View post →
Stuart Phillips (he/him)
@mackinprof · X

@Alan_Couzens @Fit_For_Golf @BradSchoenfeld When you allow people to work to fatigue, the fibre recruitment is the same regardless of load: https://t.co/t9asyxzjxR We've shown that TUT and volume modulate this response, but it's not a load-dependent outcome: https://t.co/v5sUoS1m0U https://t.co/67MgRBkv7s

Jul 30, 2023 · 8 likes · 56,047 followers View post →
加藤 光
@HK_hypertrophy · X

https://t.co/burtXPSQcO 裏付けがあった方がトレーニングは納得して追い込める

Mar 9, 2023 · 5 likes · 1,668 followers View post →
Dr Kpakpo
@DrKpakpoAcquaye · X

As you increase time under tension, especially peak tension, mitochondrial and sarcoplasmic protein synthesis are elevated by as much as by 114% and 77%, respectively.(https://t.co/zD7DAOWGZr).

Nov 9, 2022 · 10 likes · 5,862 followers View post →
Dr Kpakpo
@DrKpakpoAcquaye · X

As you increase time under tension, especially peak tension, mitochondrial and sarcoplasmic protein synthesis are elevated by as much as by 114% and 77%, respectively.(https://t.co/zD7DAOWGZr).

Nov 9, 2022 · 2 likes · 5,862 followers View post →
Hubert Olie
@hubertolie · X

RT @Mangan150: In weight training, longer time under tension and lifting to failure increases the rate of muscle protein synthesis. Liftin…

Feb 26, 2022 · 20 shares · 228 followers View post →
Alan M.
@MangoCatcher · X

RT @Mangan150: In weight training, longer time under tension and lifting to failure increases the rate of muscle protein synthesis. Liftin…

Feb 26, 2022 · 20 shares · 36 followers View post →
Xr Moaha
@XrMoaha · X

RT @Mangan150: In weight training, longer time under tension and lifting to failure increases the rate of muscle protein synthesis. Liftin…

Feb 25, 2022 · 20 shares · 54 followers View post →
Darrell Jackson
@darrell1114 · X

RT @Mangan150: In weight training, longer time under tension and lifting to failure increases the rate of muscle protein synthesis. Liftin…

Feb 25, 2022 · 20 shares · 85 followers View post →
Ivanna Coffee
@IvannaCoffee · X

RT @Mangan150: In weight training, longer time under tension and lifting to failure increases the rate of muscle protein synthesis. Liftin…

Feb 25, 2022 · 20 shares · 442 followers View post →
Muzzpol
@Muzzpol · X

RT @Mangan150: In weight training, longer time under tension and lifting to failure increases the rate of muscle protein synthesis. Liftin…

Feb 25, 2022 · 20 shares · 860 followers View post →
Dragos
@Dragos23200112 · X

RT @Mangan150: In weight training, longer time under tension and lifting to failure increases the rate of muscle protein synthesis. Liftin…

Feb 25, 2022 · 20 shares · 4 followers View post →
Robert Havercroft
@RHHealthyLiving · X

RT @Mangan150: In weight training, longer time under tension and lifting to failure increases the rate of muscle protein synthesis. Liftin…

Feb 25, 2022 · 20 shares · 28 followers View post →
kike
@FUENTESMANZULLI · X

RT @Mangan150: In weight training, longer time under tension and lifting to failure increases the rate of muscle protein synthesis. Liftin…

Feb 25, 2022 · 20 shares · 249 followers View post →
Chris Cross
@christopher_erc · X

RT @Mangan150: In weight training, longer time under tension and lifting to failure increases the rate of muscle protein synthesis. Liftin…

Feb 25, 2022 · 20 shares · 444 followers View post →
козел кефир
@cacaoXtawco · X

RT @Mangan150: In weight training, longer time under tension and lifting to failure increases the rate of muscle protein synthesis. Liftin…

Feb 25, 2022 · 20 shares · 388 followers View post →
ZOLO
@zoljar6al · X

RT @Mangan150: In weight training, longer time under tension and lifting to failure increases the rate of muscle protein synthesis. Liftin…

Feb 25, 2022 · 20 shares · 106 followers View post →
JRod Freedom
@JrodFreedom · X

RT @Mangan150: In weight training, longer time under tension and lifting to failure increases the rate of muscle protein synthesis. Liftin…

Feb 25, 2022 · 20 shares · 608 followers View post →
May The Fork Be With You
@RadicalGaiz · X

RT @Mangan150: In weight training, longer time under tension and lifting to failure increases the rate of muscle protein synthesis. Liftin…

Feb 25, 2022 · 20 shares · 326 followers View post →
P.D. Mangan Health & Freedom Maximalist
@Mangan150 · X

In weight training, longer time under tension and lifting to failure increases the rate of muscle protein synthesis. Lifting weights isn't, or shouldn't be, about moving a weight around, but effectively giving muscles the right growth stimulus. https://t.co/7clyK6FzaM

Feb 25, 2022 · 168 likes · 20 shares · 294,505 followers View post →
Nick Krontiris
@nick_krontiris · X

- "Additional studies that followed up on this work showed that contraction speed and exercise volume are also important determinants of the post-exercise anabolic response." Refs: https://t.co/12wd6P1b0z https://t.co/aJHTWLd7x7

Feb 2, 2022 · 19,451 followers View post →
Paco Tarazona
@Sabater71 · X

RT @drjohnmorley: Muscle time under tension during resistance exercise stimulates differential muscle protein sub-fractional synthetic resp…

Nov 11, 2019 · 2 shares · 1,217 followers View post →
Unya S
@UnyaS · X

RT @drjohnmorley: Muscle time under tension during resistance exercise stimulates differential muscle protein sub-fractional synthetic resp…

Nov 11, 2019 · 2 shares · 186 followers View post →
john morley
@drjohnmorley · X

Muscle time under tension during resistance exercise stimulates differential muscle protein sub-fractional synthetic responses in men https://t.co/PbXRJgMXQH

Nov 11, 2019 · 5 likes · 2 shares · 8,305 followers View post →