PLoS One July 2012 PMID 22164271

Dose-dependent effects of endotoxin on neurobehavioral functions in humans.

Jan-Sebastian Grigoleit, Jennifer S Kullmann, Oliver T Wolf, Florian Hammes, Alexander Wegner, Stephanie Jablonowski, Harald Engler, Elke Gizewski, Reiner Oberbeck, Manfred Schedlowski

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Mentions

13
Peak: 2 in Jan 2022
across 3 sources since May 2018

Extended reach

806,521
potential audience

Total likes

17,199

Video views

802,910

Mentions per month

May 2018 – Feb 2024

Where it's discussed

  • X / Twitter8 posts
  • News3 articles
  • YouTube2 videos

AI synopsis

What people are saying

Discussions highlight how the research informs understanding of fever dreams and inflammation's effects, with examples like referencing the study for measuring response times or sharing personal experiences with fever dreams. The tone combines curiosity and personal reflection, contributing to a moderate but meaningful collective engagement that emphasizes scientific relevance without deep technical analysis.

AgreementModerate agreement

Some posts acknowledge the relevance of the study, especially those referencing its usefulness for understanding response times and neurobehavioral effects.

InterestHigh interest

Posts related to personal experiences with fever dreams and references to the research show high curiosity and engagement with the topic.

EngagementModerate engagement

Participants express interest by linking personal experiences and scientific insights, indicating moderate depth in their discussions.

ImpactModerate impact

The discourse suggests the research has meaningful implications for understanding how systemic inflammation influences cognitive and emotional functions, though with limited breadth.

Abstract in brief

  • In this study, researchers investigated how different doses of endotoxin (LPS), which induces inflammation, affect various neurobehavioral functions in healthy men, showing dose-related physiological and mood changes.
  • The results revealed that while inflammation elevated cytokine levels, temperature, and anxiety, it did not impair working memory accuracy but sped up reaction times at higher doses; however, lower doses of LPS impaired long-term memory for emotional images.
  • The findings suggest that acute systemic inflammation triggers two opposing mechanisms: one that may enhance certain cognitive functions temporarily and another that impairs more complex, emotional memory processes.

Top posts

Most liked on X and Bluesky
JuleyJTrip
@JuleyJTrip · X

@aalohilanii I gotchu https://t.co/16XZ8OcZLE

May 16, 2022 · 1 like · 333 followers View post →
Black Liver Project
@BlakLivrProject · X

My holiday vacation started with a feverish flu. We talk about our experience with fever dreams. Here's the science behind it: https://t.co/dvaxPFbXAb #BlackLiverProject #MonsterInAGlass #podcast #RobRoy

Jan 27, 2019 · 1,249 followers View post →
f1nnCh4D4
@finnerdude · X

work all week, sick all weekend. taking monderp off. just awoke from another great fever dream. this one had a demon getting into a church while signing, wtf https://t.co/jtIAPFVtpp

Feb 26, 2024 · 719 followers View post →
Paul McLean
@KetoPaul · X

@simplehbean Thanks so much for sending me your paper. This reference is most helpful, especially in terms of Response Timeframes. These graphs from that study will be a useful basis for comparison with my experiment. https://t.co/otyNHAs5IV https://t.co/KEdNJMVP1C

Mar 25, 2019 · 716 followers View post →
Kelly French
@kfrench581 · X

What Are Fever Dreams? https://t.co/8eDwD7mphw via @YouTube

Jan 24, 2022 · 210 followers View post →
JUAN ARIEL JARA GUER
@Tigerariel40 · X

Dose-Dependent Effects of Endotoxin on Neurobehavioral Functions in Humans https://t.co/aNmgcQ4duW

Oct 7, 2019 · 157 followers View post →

All mentions

f1nnCh4D4
@finnerdude · X

work all week, sick all weekend. taking monderp off. just awoke from another great fever dream. this one had a demon getting into a church while signing, wtf https://t.co/jtIAPFVtpp

Feb 26, 2024 · 719 followers View post →
JuleyJTrip
@JuleyJTrip · X

@aalohilanii I gotchu https://t.co/16XZ8OcZLE

May 16, 2022 · 1 like · 333 followers View post →
Kelly French
@kfrench581 · X

What Are Fever Dreams? https://t.co/8eDwD7mphw via @YouTube

Jan 24, 2022 · 210 followers View post →
LANNOCC
@lannocc · X

What Are Fever Dreams? https://t.co/1YGMNE8wJV https://t.co/Nkiy8nwcaX

Jan 18, 2022 · 104 followers View post →
MegaNerd20
@MegaNerd18 · X

@Proton_Jon https://t.co/p8sqYNcDYu There

Jan 10, 2020 · 94 followers View post →
JUAN ARIEL JARA GUER
@Tigerariel40 · X

Dose-Dependent Effects of Endotoxin on Neurobehavioral Functions in Humans https://t.co/aNmgcQ4duW

Oct 7, 2019 · 157 followers View post →
Paul McLean
@KetoPaul · X

@simplehbean Thanks so much for sending me your paper. This reference is most helpful, especially in terms of Response Timeframes. These graphs from that study will be a useful basis for comparison with my experiment. https://t.co/otyNHAs5IV https://t.co/KEdNJMVP1C

Mar 25, 2019 · 716 followers View post →
Black Liver Project
@BlakLivrProject · X

My holiday vacation started with a feverish flu. We talk about our experience with fever dreams. Here's the science behind it: https://t.co/dvaxPFbXAb #BlackLiverProject #MonsterInAGlass #podcast #RobRoy

Jan 27, 2019 · 1,249 followers View post →
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