Cold Spring Harb Perspect Med September 2011 PMID 22229120

Origins of HIV and the AIDS pandemic.

Paul M Sharp, Beatrice H Hahn

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Mentions

185
Peak: 4 in Jan 2025
across 6 sources since Sep 2019

Extended reach

79,432
potential audience

Total likes

194

Video views

7,790

Mentions per month

Sep 2019 – Nov 2025

Where it's discussed

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AI synopsis

What people are saying

The overall discussions reflect a strong curiosity and support for scientific explanations about HIV's origins, with many referencing research articles and history, using technical terms like 'cross-species transmission' and 'bushmeat hunting.' The tone varies from enthusiastic to skeptical, and some posts challenge misconceptions, which contributes to a nuanced understanding among engaged audiences.

AgreementModerate agreement

Most discussions align with the scientific consensus that HIV originated from cross-species transmission through bushmeat hunting, though some posts disagree with misinformation or question specific details.

InterestHigh interest

The discussion shows high interest, with many people referencing detailed studies, historical timelines, and emphasizing the importance of understanding HIV's origin.

EngagementHigh engagement

Several users actively analyze the mechanisms of transmission, cite scientific articles, and debate related topics, indicating deep engagement.

ImpactModerate impact

While some posts promote awareness of HIV’s origins, the overall impact appears moderate, mainly affecting those already interested or informed about zoonotic diseases.

Abstract in brief

  • The origins of HIV and AIDS stem from cross-species transmissions of simian immunodeficiency viruses (SIVs) from African primates, with HIV-1 group M emerging from a transfer involving chimpanzees in Cameroon.
  • Host restriction factors have played a critical role in limiting or enabling these cross-species transmissions, shaping the emergence of HIV as a zoonotic disease.
  • The study of genetic changes during these host jumps helps us understand how successful transmissions occur and assess the potential for future zoonotic infections.]

Top posts

Most liked on X and Bluesky
Foreign body
@CorpusAlienumm · X

Nope, it’s wrong. Cross transmission of SIVs from primate to humans is not within the context of sexual encounter between species. But it is due to bushmeat hunting, aka perburuan hewan liar. https://t.co/9yfCU7s2jU https://t.co/SBCXyLdEra https://t.co/3Y1sUpdA0r https://t.co/J3WivAw2ys

Jan 4, 2025 · 26 likes · 4 shares · 15,922 followers View post →
Felix Moronta
@morontafelix · X

Algunas referencias: Origin story https://t.co/pMi4evQQt2 Origins of HIV and the AIDS Pandemic https://t.co/jXQYd2oIMc Y también: https://t.co/OeSfLEabWb

Dec 28, 2021 · 6 likes · 2 shares · 7,925 followers View post →
FUTUREC00L
@FUTUREC00L · X

https://t.co/R9zUW30920 if anyone is interested here is a paper describing the phylogenic origins of the HIV virus

Dec 11, 2019 · 5 likes · 2,466 followers View post →
Pope_Bane
@Pope_Bane · X

@firewirenz @Lilith_Atheist If you think it originated from gay people, you're probably just another ill-informed religious bigot. Origins of HIV and the AIDS pandemic https://t.co/oZ5zGI1mGd

Jan 20, 2024 · 5 likes · 1,729 followers View post →
Antonio
@TonyBaduy · X

@factbid @IanCopeland5 @Debunk_the_Funk Genetic studies have shown HIV appeared at some point in the 30's, probably from hunters that handled bush meat, and it happened at least twice in different places. https://t.co/yIu1l2iUrP

Oct 4, 2023 · 2 likes · 619 followers View post →
Jaime Espinosa
@jaime_eem · X

LECTURA INTERESANTE PARA ANTES DE DORMIR "ORIGIN OF HIV/AIDS" https://t.co/I5uxYvzR1k

Sep 16, 2019 · 2 likes · 471 followers View post →

All mentions

Mr M
@MrMnd73 · X

@MessmersSoldier @HeslopJohn @I_amMukhtar HIV was a zootropic virus, which originated in primates. It was likely started through hunting "bushmeat" through the transfer of blood "or other bodily fluids. Origins of HIV and the AIDS Pandemic - PMC https://t.co/So7jrzc2Zc Your claim of "bigotry" has absolutely no basis...

Nov 20, 2025 · 4,558 followers View post →
Megan Rennich
@meganrennich · X

@Toronto416CAD @william_lou Here you go: Sharp, P. M., & Hahn, B. H. (2011). Origins of HIV and the AIDS pandemic. Cold Spring Harbor perspectives in medicine, 1(1), a006841. https://t.co/hwXlYxw4yl

Feb 3, 2025 · 72 followers View post →
knowledge_eater
@EaterKnowledge · X

RT @CorpusAlienumm: Nope, it’s wrong. Cross transmission of SIVs from primate to humans is not within the context of sexual encounter betw…

Jan 5, 2025 · 4 shares · 85 followers View post →
Antidote
@xpamol · X

RT @CorpusAlienumm: Nope, it’s wrong. Cross transmission of SIVs from primate to humans is not within the context of sexual encounter betw…

Jan 4, 2025 · 4 shares · 202 followers View post →
darkCHOCOLATE
@natureadmirer8 · X

RT @CorpusAlienumm: Nope, it’s wrong. Cross transmission of SIVs from primate to humans is not within the context of sexual encounter betw…

Jan 4, 2025 · 4 shares · 679 followers View post →
Foreign body
@CorpusAlienumm · X

Nope, it’s wrong. Cross transmission of SIVs from primate to humans is not within the context of sexual encounter between species. But it is due to bushmeat hunting, aka perburuan hewan liar. https://t.co/9yfCU7s2jU https://t.co/SBCXyLdEra https://t.co/3Y1sUpdA0r https://t.co/J3WivAw2ys

Jan 4, 2025 · 26 likes · 4 shares · 15,922 followers View post →
floraltsunami
@floraltsunami · X

@aisling_bn not that hard to do a google search https://t.co/Bu8CB79xrD https://t.co/g1omrIf90G https://t.co/B4118Kihdi

Aug 30, 2024 · 12 followers View post →
Meri Perkins
@mlperk1 · X

@pizzapicklespur That's hopeful news. On that post, I'll head for bed and read my favorite fairy tales till I sleep: https://t.co/fw95FPtavM https://t.co/MoEEkAUcih (have u got the rest of this in your catbox?)

May 9, 2024 · 1 like · 1,298 followers View post →
FactsDontLie
@TruthCampaigns · X

Origins of HIV and the AIDS pandemic - PubMed I wonder if they use so many primates in in science research & monkey kidney cells in vaccines where it might have started!

Mar 25, 2024 · 1,926 followers View post →
Maga-nificent
@SusieAlverson · X

Origins of HIV and the AIDS Pandemic - PMC https://t.co/AIZ73kgM7f

Feb 16, 2024 · 3,771 followers View post →
Pope_Bane
@Pope_Bane · X

@firewirenz @Lilith_Atheist If you think it originated from gay people, you're probably just another ill-informed religious bigot. Origins of HIV and the AIDS pandemic https://t.co/oZ5zGI1mGd

Jan 20, 2024 · 5 likes · 1,729 followers View post →
BGLTHMND
@BGLTHMND · X

@cappsie @TsuDhoNimh @djt10 @handmadekathy @Augusti03401363 @Juanita87722370 @club_gut @eucalyptus_life @crabb_vicki @hoonior5 @FrankDElia7 @ChrisJohnsonMD @TheFrankmanMN @davideyoungmd @IainMulady @doritmi @JCDeardeuff @TruthTwt @Izzitreally2 @Jccalmond2 @Monstercoyliar @krebiozen @iXeno @TweetOfSteiner @SkepticalMutant @ianfmusgrave @BlueLionBlog @thisisnothappen @natedoromal @Blackcatprowl3 @mcfunny @isa_picard @HawkInATX @VVDeingott @foofdawg @4thEchelon22 @TinFoilAwards @ktibus @F250Roush @MsTrixter @Kathmarval @mrhawkes @ThomasHarrigan8 @BigBruce1972 @keithccurtis @John010708 @lewbloch @somethinsomethi @lizditz Cant find it right now, but here's another one, a full text study. ORIGINS OF HIV AND THE AIDS PANDEMIC https://t.co/N4MwYxN5XM

Dec 30, 2023 · 2,983 followers View post →
Katt D
@Kattdd999 · X

@DopplerEffect93 @NikolaTshare @drarce @ViroLIEgy "Origins of HIV and the AIDS Pandemic" ????

Dec 9, 2023 · 810 followers View post →
Antonio
@TonyBaduy · X

@factbid @IanCopeland5 @Debunk_the_Funk Genetic studies have shown HIV appeared at some point in the 30's, probably from hunters that handled bush meat, and it happened at least twice in different places. https://t.co/yIu1l2iUrP

Oct 4, 2023 · 2 likes · 619 followers View post →
EchoLong
@goshia0 · X

RT @usa_abdyvz: @Ferhatarslandr https://t.co/Bdgu16Oggf

Aug 22, 2023 · 1 share · 714 followers View post →
Ycak
@YCakABD · X

@Ferhatarslandr https://t.co/Bdgu16Oggf

Aug 22, 2023 · 1 share · 346 followers View post →
Concerned Citizen
@NoVoice2Small · X

@RamieMokone @DZumaSambudla https://t.co/rjd6J21pfw.

May 11, 2023 · 337 followers View post →
Lisa
@WhiteLace83 · X

@JoshWalkos Why lie? https://t.co/WPbusvGZ3Q Origins of HIV and the Aids pandemic https://t.co/pF0GbZAODL 25 years of HIV1 research - progress and perspectives https://t.co/uSDLsCFKTk The early years of HIV research: integrating clinical and basic research 1/

May 7, 2023 · 2 likes · 113 followers View post →
Pray to Joe Pesci 心
@pray2pesci · X

@ax2n38 @BrianNazarenus @MucusMucous @megafant1 @willsworldview @EdgeZeto @DarkCowboyGod @Wolfpak561 @StillDizzy2 @TessFromWessex @wiguy45 @hubie0 @Avic_Wins @PatricktheB @1pckt @OnkelFester @OnlyaMoment3 @Melanie33720945 @D1scoJerrys @Raven4212 @RossGilroy @JH747474 @zypisfy @ErikHagstrom1 @AGwraig @dirk_fasshauer @Canna420Uk @michael43081938 @Cern_lXXl @parentingtired @muath_5ii @Chortling_Man @foo_oom @AwayFromTheKeys @Ihonestlydont19 @orna_verum @remofjacob @HaircutSpock @The_Real_BiM @WooWooSpaceJew @_DenizenX @thorinajarooft @War_Artificer @Panimu @kevin_witchell @AndrewRChapman @MindfulDamage https://t.co/3hT6rQcdBi

Jan 16, 2023 · 2,227 followers View post →
PositiveLiving
@TheAsthmaCures · X

Origins of HIV and the AIDS Pandemic - Cold Spring Harb Perspect Med https://t.co/VT9gYNqh3v Abstract. Acquired immunodeficiency syndrome (AIDS) of humans is caused by two lentiviruses, human immunodeficiency viruses types 1 and 2 (HIV-1 ...

Sep 22, 2022 · 182 followers View post →
Straight Forward Thoughts.
@ThatLowkeyJo · X

However, one transmission event, involving SIVcpz from chimpanzees in southeastern Cameroon, gave rise to HIV-1 group M-the principal cause of the AIDS pandemic. https://t.co/mv3qETrofU

Jul 4, 2022 View post →
Jerry Dean Bowers
@vipertoxin · X

» Origins of HIV and the AIDS Pandemic - PMC https://t.co/6iUVxph4tU

May 19, 2022 · 557 followers View post →
André
@Synsei1 · X

@MuffyDeadinside @megamomof10 @grgpetro @JoanofArc777777 @mentoringwithm1 https://t.co/3bmKwjZk4d

Feb 10, 2022 · 2,779 followers View post →
Annie Aitken
@patriot1959usa · X

https://t.co/MgdppBvKa8

Jan 21, 2022 · 504 followers View post →
Icayera
@Icayera · X

RT @morontafelix: Algunas referencias: Origin story https://t.co/pMi4evQQt2 Origins of HIV and the AIDS Pandemic https://t.co/jXQYd2oIMc…

Dec 29, 2021 · 2 shares · 186 followers View post →
Felix Moronta
@morontafelix · X

Algunas referencias: Origin story https://t.co/pMi4evQQt2 Origins of HIV and the AIDS Pandemic https://t.co/jXQYd2oIMc Y también: https://t.co/OeSfLEabWb

Dec 28, 2021 · 6 likes · 2 shares · 7,925 followers View post →
Chris Wymant @chriswymant.bsky.social
@ChrisWymant · X

Keynote by Martine Peeterson. Time&place not same for zoonosis, origin of epidemic, recognition of epidemic. Recap of reservoirs, zoonoses and diversification of HIV-1 & -2 (see great summary at https://t.co/n3d7vICymO)...

Sep 15, 2021 · 967 followers View post →
Valan
@valanvir · X

RT @Cornymel: @macroliter I give a lecture on this every year... There is not a great single review IMO, but here are a few good resources…

Aug 4, 2021 · 1 share · 52 followers View post →
Melissa Kane PhD
@Cornymel · X

@macroliter I give a lecture on this every year... There is not a great single review IMO, but here are a few good resources DOI: 10.1101/cshperspect.a006841, 10.1016/S1473-3099(10)70186-9 , 10.1016/j.molmed.2011.12.001, 10.1016/j.virol.2016.05.003, 10.1126/science.1256739

Aug 4, 2021 · 1 like · 1 share · 1,048 followers View post →
Byron
@ByronHsu2 · X

@SebastianL17 @moifo14 @MugabeBobby @jacnive @MadiBoity No, I never agreed with Judy's false narrative. I just explained the hunting hypothesis for the zoonose HIV. Hunters do get injured when butchering wild animals, and this is done in many other countries like China. Origins of HIV and the AIDS Pandemic https://t.co/UilRQYG1QG

Jan 23, 2021 · 797 followers View post →
Byron
@ByronHsu2 · X

@AlbertoThomas @DanielZeichner @CambridgeIndy HIV and Ebola are prjven zoonoses. Origins of HIV and the AIDS Pandemic https://t.co/2jxROpTTlS

Dec 19, 2020 · 797 followers View post →
Dr. Jonathon Gass, PhD, MPH
@gass_jonathon · X

I have always returned to Origins of HIV and the AIDS Pandemic by Sharp and Hahn (2011) as a great primer for teaching about spillover of lentiviruses from chimps and gorillas (SIVcpz & SIVgor) to humans (HIV-1,2) https://t.co/ofCir7Thbs

Sep 30, 2020 · 102 followers View post →
Ammu Neuroscience
@ammuneuroscien2 · X

a006841-a006841. ISSN 2157-1422. PMC PMC3234451 |pmc= incorrecto (ayuda). PMID 22229120. doi:10.1101/cshperspect.a006841. Barré-Sinoussi, F (20 de mayo de 1983). «Isolation of a T-lymphotropic retrovirus from a patient at risk for acquired immune deficiency syndrome (AIDS).».

Sep 11, 2020 · 2,743 followers View post →
Ammu Neuroscience
@ammuneuroscien2 · X

313 (5786): 523-526. ISSN 0036-8075. PMC PMC2442710 |pmc=incorrecto (ayuda). PMID 16728595. doi:10.1126/science.1126531. Sharp, P. M.; Hahn, B. H. (1 de septiembre de 2011). «Origins of HIV and the AIDS Pandemic». Cold Spring Harbor Perspectives in Medicine (en inglés) 1 (1):

Sep 11, 2020 · 2,743 followers View post →
Dr. Eddie Ramirez
@EddieRDMD · X

AIDS, another epidemic caused by eating the wrong food: "The most commonly accepted theory is that of the 'hunter'. [HIV] was transferred to humans as a result of chimps being killed and eaten." Journal: https://t.co/aQsMFhXbCG Press: https://t.co/b28LLVeLvi @_atanas_

Apr 19, 2020 · 1 like · 4,726 followers View post →
John Smith⚛ (Explorer of Reality)
@doofgeek4011 · X

Origins of HIV and the AIDS Pandemic https://t.co/cOUmqeEPfW

Jan 22, 2020 · 4,064 followers View post →
FUTUREC00L
@FUTUREC00L · X

https://t.co/R9zUW30920 if anyone is interested here is a paper describing the phylogenic origins of the HIV virus

Dec 11, 2019 · 5 likes · 2,466 followers View post →
O Avantesma
@PikasLePepe · X

@biavillena @GLOBLIN_ALUCINA @candace_nisa De nada: https://t.co/lQUp2UWS1l

Dec 2, 2019 · 83 followers View post →
Jaime Espinosa
@jaime_eem · X

LECTURA INTERESANTE PARA ANTES DE DORMIR "ORIGIN OF HIV/AIDS" https://t.co/I5uxYvzR1k

Sep 16, 2019 · 2 likes · 471 followers View post →