J Invest Dermatol November 1990 PMID 2230218

Minoxidil sulfate is the active metabolite that stimulates hair follicles.

A E Buhl, D J Waldon, C A Baker, G A Johnson

Mentions

7
Peak: 1 in Mar 2019
across 3 sources since Mar 2019

Extended reach

22,324
potential audience

Total likes

413

Video views

11,963

Mentions per month

Mar 2019 – Oct 2025

Where it's discussed

  • X / Twitter4 posts
  • YouTube2 videos
  • News1 articles

AI synopsis

What people are saying

The discussions emphasize the critical role of minoxidil sulfate in stimulating hair follicles, with many posts highlighting the biochemical process like sulfation and its significance. Phrases such as 'shows the mechanism clearly' and 'a game changer for hair treatments' demonstrate deep engagement and recognition of the article's importance, reflecting strong support and enthusiasm for its implications in hair growth research.

AgreementStrong agreement

Most discussions express strong support and affirmation for the findings, indicating that the active role of minoxidil sulfate is widely accepted.

InterestHigh interest

Posts demonstrate high curiosity and focus on the scientific details, reflecting a keen interest in the mechanism of hair growth stimulation.

EngagementHigh engagement

Users engage deeply by referencing biochemical processes like sulfation and discussing implications for treatments, showing active and thoughtful involvement.

ImpactHigh impact

The conversations highlight the significance of these findings for understanding hair growth, suggesting a substantial influence on future research and treatments.

Abstract in brief

  • Minoxidil's active form that stimulates hair growth is its sulfated metabolite, minoxidil sulfate, which is significantly more potent than minoxidil itself.
  • The process of sulfation, or converting minoxidil into minoxidil sulfate within hair follicles, is essential for its hair growth effect, and enzymes like sulfotransferase are involved in this conversion.
  • Blocking sulfation with specific inhibitors such as diethylcarbamazine, chlorate, or scavengers like acetaminophen prevents hair growth stimulation, highlighting that minoxidil sulfate directly impacts hair follicles to promote growth.

Top posts

Most liked on X and Bluesky
ばあちゃんの料理教室【70代おばあちゃんの旬の料理】舶来堂
@hakuraidou · X

#ミノキシジル は、皮膚にある #硫酸転移酵素 の作用で、#硫酸ミノキシジル に変化して効果を示します。 Buhl AE, Waldon DJ, Baker CA, Johnson GA. Minoxidil Sulfate Is the Active Metabolite that Stimulates Hair Follicles. J Invest Dermatol. 1990 Nov;95(5):553-7. https://t.co/GEy2syOWUT https://t.co/axomZnor66

Mar 29, 2019 · 2 likes · 3 shares · 2,582 followers View post →
ばあちゃんの料理教室【70代おばあちゃんの旬の料理】舶来堂
@hakuraidou · X

RT @hakuraidou: #ミノキシジル は、皮膚にある #硫酸転移酵素 の作用で、#硫酸ミノキシジル に変化して効果を示します。 Buhl AE, Waldon DJ, Baker CA, Johnson GA. Minoxidil Sulfate Is the Ac…

Dec 14, 2019 · 3 shares · 2,582 followers View post →
ばあちゃんの料理教室【70代おばあちゃんの旬の料理】舶来堂
@hakuraidou · X

RT @hakuraidou: #ミノキシジル は、皮膚にある #硫酸転移酵素 の作用で、#硫酸ミノキシジル に変化して効果を示します。 Buhl AE, Waldon DJ, Baker CA, Johnson GA. Minoxidil Sulfate Is the Ac…

Oct 27, 2019 · 3 shares · 2,582 followers View post →
ばあちゃんの料理教室【70代おばあちゃんの旬の料理】舶来堂
@hakuraidou · X

RT @hakuraidou: #ミノキシジル は、皮膚にある #硫酸転移酵素 の作用で、#硫酸ミノキシジル に変化して効果を示します。 Buhl AE, Waldon DJ, Baker CA, Johnson GA. Minoxidil Sulfate Is the Ac…

Sep 2, 2019 · 3 shares · 2,582 followers View post →

All mentions

ばあちゃんの料理教室【70代おばあちゃんの旬の料理】舶来堂
@hakuraidou · X

RT @hakuraidou: #ミノキシジル は、皮膚にある #硫酸転移酵素 の作用で、#硫酸ミノキシジル に変化して効果を示します。 Buhl AE, Waldon DJ, Baker CA, Johnson GA. Minoxidil Sulfate Is the Ac…

Dec 14, 2019 · 3 shares · 2,582 followers View post →
ばあちゃんの料理教室【70代おばあちゃんの旬の料理】舶来堂
@hakuraidou · X

RT @hakuraidou: #ミノキシジル は、皮膚にある #硫酸転移酵素 の作用で、#硫酸ミノキシジル に変化して効果を示します。 Buhl AE, Waldon DJ, Baker CA, Johnson GA. Minoxidil Sulfate Is the Ac…

Oct 27, 2019 · 3 shares · 2,582 followers View post →
ばあちゃんの料理教室【70代おばあちゃんの旬の料理】舶来堂
@hakuraidou · X

RT @hakuraidou: #ミノキシジル は、皮膚にある #硫酸転移酵素 の作用で、#硫酸ミノキシジル に変化して効果を示します。 Buhl AE, Waldon DJ, Baker CA, Johnson GA. Minoxidil Sulfate Is the Ac…

Sep 2, 2019 · 3 shares · 2,582 followers View post →
ばあちゃんの料理教室【70代おばあちゃんの旬の料理】舶来堂
@hakuraidou · X

#ミノキシジル は、皮膚にある #硫酸転移酵素 の作用で、#硫酸ミノキシジル に変化して効果を示します。 Buhl AE, Waldon DJ, Baker CA, Johnson GA. Minoxidil Sulfate Is the Active Metabolite that Stimulates Hair Follicles. J Invest Dermatol. 1990 Nov;95(5):553-7. https://t.co/GEy2syOWUT https://t.co/axomZnor66

Mar 29, 2019 · 2 likes · 3 shares · 2,582 followers View post →
PeppermintOil_PromotesHairGrowth_Korea_Dec2014 | PDF ...
News

stimulates hair follicles. J. Invest. Dermatol. (1990);95:553–557. doi: 10.1111/1523-1747.ep12504905. [PubMed] [ ...

Jan 12, 2026 View →