Br J Pharmacol September 2012 PMID 22486393

Exercise acts as a drug; the pharmacological benefits of exercise.

J Vina, F Sanchis-Gomar, V Martinez-Bello, M C Gomez-Cabrera

Mentions

71
Peak: 30 in Nov 2022
across 6 sources since Jul 2017

Extended reach

1,070,402
potential audience

Total likes

26,298

Video views

879,510

Mentions per month

Jul 2017 – Nov 2025

Where it's discussed

  • X / Twitter55 posts
  • News6 articles
  • Facebook5 posts
  • YouTube3 videos
  • Bluesky1 posts
  • Instagram1 posts

AI synopsis

What people are saying

The collective discussions clearly focus on the powerful health benefits of exercise, with many posts excitedly calling it a form of medicine or a pharmaceutical breakthrough, using strong language like 'unbelievable' and expressions of scientific validation. This enthusiasm and in-depth exploration indicate a high level of interest and perceived impact in how exercise could revolutionize health and medicine.

AgreementStrong agreement

Most discussions strongly agree with the idea that exercise acts like a drug and provide health benefits, as seen in posts emphasizing exercise's pharmacological effects and calling it a 'first exercise pill'.

InterestHigh interest

Posts demonstrate high enthusiasm and curiosity about the concept, with expressions like 'Unbelievable', 'Wow', and mentions of potential revolutionary treatments.

EngagementHigh engagement

Many comments delve into broader implications, such as preventing diseases or contemplating the societal impact, indicating deep engagement with the topic.

ImpactHigh impact

The discussions highlight a significant perceived influence, suggesting that the idea of exercise as a drug could impact health practices and scientific understanding, shown by statements about science 'proving' benefits and the potential for a 'first exe

Abstract in brief

  • Exercise has been shown to provide many health benefits, similar to a drug, including promoting overall health and extending lifespan.
  • Proper dosing of exercise is crucial, as the body adapts to it through specific molecular signaling pathways; understanding these pathways helps in prescribing the right exercise regimen.
  • Exercise also has powerful psychological effects, acting like a psychoactive drug that can induce relaxation or even addiction in some individuals, and caution is needed especially for those who are severely ill.]

Top posts

Most liked on X and Bluesky
Julio Rodríguez, PhD | Genética Clínica
@bitacorabeagle · X

El ejercicio es tan beneficioso para la salud que debería ser considerado como un fármaco. Previene muchas enfermedades y promueve una longevidad saludable. Puede considerarse como tratamiento de enfermedades cardiovasculares, depresión o diabetes. https://t.co/oX9Kpog28I https://t.co/ggbpfnbYd8

Feb 7, 2021 · 29 likes · 11 shares · 29,454 followers View post →
Dr Jon K
@JonKMD · X

Exercise is literally the easiest drug we have access to As simple as 10 pushups anytime Unleashes an internal pharmacy of feeling good https://t.co/uoFyncOszH

Nov 8, 2024 · 8 likes · 9 shares · 3,238 followers View post →
Oonabot
@Oonabot · X

ZOMG hook me up with a 516 dealer STAT https://t.co/Onr6rSSY4p

Nov 4, 2022 · 3 likes · 1 share · 7,367 followers View post →
Abnel Alecrim
@abnelalecrim · X

@FredLAFernandes A ciência comprovou que o exercício é tão eficaz para regular e promover saúde que cura doenças. O exercício age como uma droga e tem benefícios farmacológicos, e a atenção deve ser dada à dosagem e às variações individuais entre os pacientes. (https://t.co/1M3lxDZMHa)

Sep 20, 2020 · 2 likes · 1 share · 4,103 followers View post →
MorozkoForge
@MorozkoForge · X

Is "exercise a drug" like this article suggests? Or, are drugs just poor attempts to mimic the benefits of exercise? https://t.co/fzNxkhGDZm

Jan 5, 2020 · 2 likes · 2,447 followers View post →
kea
@prisonicfaery · X

while this is technically good it's also extremely depressing. Yet another solution to a capitalist problem that aims to keep you working for longer, now you won't even have to work out to stay fit, you just take a couple pills and you can keep working. https://t.co/YSgDhOdEXC

Nov 3, 2022 · 2 likes · 1,639 followers View post →

All mentions

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AsapSCIENCE · Nov 3, 2022 878,826 views
Cathy Probst
@probst_cat89391 · X

https://t.co/22DpaTr7vS Exercise acts as a drug; the pharmacological benefits of exercise

Nov 29, 2025 · 176 followers View post →
Jesse ●△■
@eduar012514 · X

RT @JonKMD: Exercise is literally the easiest drug we have access to As simple as 10 pushups anytime Unleashes an internal pharmacy of f…

Aug 29, 2025 · 9 shares View post →
Lux
@luxylair · X

RT @JonKMD: Exercise is literally the easiest drug we have access to As simple as 10 pushups anytime Unleashes an internal pharmacy of f…

Jul 1, 2025 · 9 shares · 747 followers View post →
Simple Science Fitness
@ssfitness.bsky.social · Bluesky

Exercise is so powerful that it may be considered as a psychoactive drug: pubmed.ncbi.nlm.nih.gov/22486393/ #exercise #fitness #health

Jun 2, 2025 · 1 like View post →
Simple Science Fitness
@SimpleSciFit · X

Exercise is so powerful that it may be considered as a psychoactive drug: https://t.co/6n0I2WmHVv #exercise #fitness #health

Jun 2, 2025 · 666 followers View post →
Gulban
@GulbanSaylam · X

RT @JonKMD: Exercise is literally the easiest drug we have access to As simple as 10 pushups anytime Unleashes an internal pharmacy of f…

Apr 1, 2025 · 9 shares · 9 followers View post →
Melaniortega05@gmail
@melaniortega5 · X

RT @JonKMD: Exercise is literally the easiest drug we have access to As simple as 10 pushups anytime Unleashes an internal pharmacy of f…

Feb 7, 2025 · 9 shares · 91 followers View post →
Tatti
@Tattitix · X

RT @JonKMD: Exercise is literally the easiest drug we have access to As simple as 10 pushups anytime Unleashes an internal pharmacy of f…

Feb 7, 2025 · 9 shares · 7 followers View post →
Michele_Renee_USA
@MRM102480 · X

RT @JonKMD: Exercise is literally the easiest drug we have access to As simple as 10 pushups anytime Unleashes an internal pharmacy of f…

Nov 8, 2024 · 9 shares · 3,207 followers View post →
Masey
@MaseyLeah · X

RT @JonKMD: Exercise is literally the easiest drug we have access to As simple as 10 pushups anytime Unleashes an internal pharmacy of f…

Nov 8, 2024 · 9 shares · 2,107 followers View post →
ℜ
@RoseMarieMusk · X

RT @JonKMD: Exercise is literally the easiest drug we have access to As simple as 10 pushups anytime Unleashes an internal pharmacy of f…

Nov 8, 2024 · 9 shares · 1,829 followers View post →
Dr Jon K
@JonKMD · X

Exercise is literally the easiest drug we have access to As simple as 10 pushups anytime Unleashes an internal pharmacy of feeling good https://t.co/uoFyncOszH

Nov 8, 2024 · 8 likes · 9 shares · 3,238 followers View post →
Mickael Marvyn Lacrosse
@LeoganeMickael · X

This Is The First Exercise PILL, And It’s Unbelievable https://t.co/GDxlSM0eV0 via @YouTube

Apr 17, 2024 · 562 followers View post →
Arhanghelul Ostatic
@TrueSocialRo · X

This Is The First Exercise PILL, And It’s Unbelievable https://t.co/iMgL6IKzZj https://t.co/Fj3MU3tPPO

Feb 2, 2023 · 211 followers View post →
ekokepe
@ekokepe · X

But there is the catch! This Is The First Exercise PILL, And It’s Unbelievable https://t.co/culIFYjmUW via @YouTube

Nov 12, 2022 · 362 followers View post →
Ultra-Cipaya
@UltraCipaya · X

@Moniquebaires vamos que ya falta poco Moniiiii https://t.co/42TnQO30wH AGUANTE LA CIENCIA Y LA TECNOLOGÍA jaja

Nov 8, 2022 · 2 likes · 385 followers View post →
protozeloz
@protozeloz · X

https://t.co/cYaBGD68KD

Nov 8, 2022 · 239 followers View post →
n
@wiznade · X

Eercise pill! Sounds interesting https://t.co/mv2ckC3hrk

Nov 8, 2022 · 130 followers View post →
Myron AI artist
@seirdotmk · X

Апче наместо вежбање? https://t.co/ArUv4AtB2c

Nov 7, 2022 · 7,279 followers View post →
Ravick Bitencourt
@Ravick_BlueLion · X

FINALMENTE! This Is The First Exercise PILL, And It’s Unbelievable https://t.co/SShp4Z8cBQ via @YouTube

Nov 6, 2022 · 165 followers View post →
ian
@ianfat · X

This Is The First Exercise PILL, And It’s Unbelievable https://t.co/fXt2vJKBiD

Nov 6, 2022 · 592 followers View post →
James-N LEE-ANGEL
@Theanphropy · X

This Is The First Exercise PILL, And It’s Unbelievable https://t.co/OWZ2knAW1J via @YouTube GW501516 also exrecise helps prevent 25 diseases from: neurodegenerative to cardiovascular; from pulmonary to reproductive system, from metabolic to nervous system!

Nov 5, 2022 · 213 followers View post →
James-N LEE-ANGEL
@Theanphropy · X

RT @Theanphropy: This Is The First Exercise PILL, And It’s Unbelievable https://t.co/OWZ2knAW1J via @YouTube

Nov 5, 2022 · 1 share · 213 followers View post →
James-N LEE-ANGEL
@Theanphropy · X

This Is The First Exercise PILL, And It’s Unbelievable https://t.co/OWZ2knAW1J via @YouTube

Nov 5, 2022 · 1 like · 1 share · 213 followers View post →
Grizzly's Lab
@uibbs2 · X

I liked a YouTube video https://t.co/SJlkOh54Ne This Is The First Exercise PILL, And It’s Unbelievable

Nov 5, 2022 · 127 followers View post →
Merry Smith
@MerrySmithNFT · X

RT @Oonabot: ZOMG hook me up with a 516 dealer STAT https://t.co/Onr6rSSY4p

Nov 4, 2022 · 1 share · 19 followers View post →
Oonabot
@Oonabot · X

ZOMG hook me up with a 516 dealer STAT https://t.co/Onr6rSSY4p

Nov 4, 2022 · 3 likes · 1 share · 7,367 followers View post →
F**K Trump
@welplookathim · X

This Is The First Exercise PILL, And It’s Unbelievable https://t.co/sLVRSGyXiv

Nov 4, 2022 · 1,906 followers View post →
خليل - Khaleel
@KhaleelMalki · X

This Is The First Exercise PILL, And It’s Unbelievable - https://t.co/uWGZyNdqdO

Nov 4, 2022 · 428 followers View post →
Lorena Flores Agüero
@lorenaflag · X

This Is The First Exercise PILL, And It’s Unbelievable https://t.co/0soe8xpIty a través de @YouTube

Nov 4, 2022 · 8,058 followers View post →
MediaREDEF
@MediaREDEF · X

This Is The First Exercise PILL, And It’s Unbelievable (@mitchellmoffit - @AsapSCIENCE) https://t.co/dxZVku1AYq

Nov 4, 2022 · 1 like · 19,997 followers View post →
Pabli!
@OmarBessa · X

Jesus Christ https://t.co/VLMEjgdRWe

Nov 4, 2022 · 1 like · 2,022 followers View post →
Ryan Brown
@RyanBdoesntweet · X

This Is The First Exercise PILL, And It’s Unbelievable https://t.co/P4mZZoaUeB via @YouTube

Nov 4, 2022 · 291 followers View post →
Andy
@andybeerrx · X

This Is The First Exercise PILL, And It’s Unbelievable https://t.co/fi9JdDsSiU via @YouTube

Nov 4, 2022 · 513 followers View post →
blubber_bones
@blubber_bones · X

https://t.co/q99caQK9pK

Nov 3, 2022 · 1,111 followers View post →
kea
@prisonicfaery · X

while this is technically good it's also extremely depressing. Yet another solution to a capitalist problem that aims to keep you working for longer, now you won't even have to work out to stay fit, you just take a couple pills and you can keep working. https://t.co/YSgDhOdEXC

Nov 3, 2022 · 2 likes · 1,639 followers View post →
Lilith
@milky_b0nes · X

here it is if ur interested!! https://t.co/lPW8hR8VxF

Nov 3, 2022 · 959 followers View post →
Ines Cozzo
@InesCozzo · X

Eu tinha encontrado meu presente de Natal... até chegar aos 7min desse vídeo... De qualquer forma, como uma pessoa que se exercita (Yay!) mas detesta fazer isso (confesso

Nov 3, 2022 · 1,284 followers View post →
3rdEyeAm
@HiveMindMilitia · X

Excercise pill? https://t.co/CKIiROILx8

Nov 3, 2022 · 1,385 followers View post →
OZ
@OZmaster_CB · X

this how we stay fit in the matrix https://t.co/IyT0hj79xc

Nov 3, 2022 · 616 followers View post →
Geeks are Sexy
@geeksaresexy · X

The First Exercise PILL Could Soon be a Reality [Science Video] https://t.co/6lSIOYuUeq https://t.co/tM3NzEgX1Y

Nov 3, 2022 · 69,089 followers View post →
Anubhav Agarwal
@AnubhavSeo · X

This Is The First Exercise PILL, And It’s Unbelievable https://t.co/aI95rLF3u4

Nov 3, 2022 · 131 followers View post →
mramos18
@MbraRamos · X

Exercise acts as a drug; the pharmacological benefits of exercise https://t.co/s02nQSJeee

Apr 9, 2021 · 9 followers View post →
MenteyCuerpo
@cuerpo_mentey · X

RT @bitacorabeagle: El ejercicio es tan beneficioso para la salud que debería ser considerado como un fármaco. Previene muchas enfermedades…

Feb 7, 2021 · 11 shares · 463 followers View post →
Pilar Esteban Peñalba
@penalba_pilar · X

RT @bitacorabeagle: El ejercicio es tan beneficioso para la salud que debería ser considerado como un fármaco. Previene muchas enfermedades…

Feb 7, 2021 · 11 shares · 59 followers View post →
Liepard Lia
@LiepardLia · X

RT @bitacorabeagle: El ejercicio es tan beneficioso para la salud que debería ser considerado como un fármaco. Previene muchas enfermedades…

Feb 7, 2021 · 11 shares · 197 followers View post →
Laia Ordonez
@laiaordonez · X

RT @bitacorabeagle: El ejercicio es tan beneficioso para la salud que debería ser considerado como un fármaco. Previene muchas enfermedades…

Feb 7, 2021 · 11 shares · 460 followers View post →
Ambientóloga Arriacense
@A_Arriacense · X

RT @bitacorabeagle: El ejercicio es tan beneficioso para la salud que debería ser considerado como un fármaco. Previene muchas enfermedades…

Feb 7, 2021 · 11 shares · 125 followers View post →
Manuel Collado
@mcollado_CIMUS · X

RT @bitacorabeagle: El ejercicio es tan beneficioso para la salud que debería ser considerado como un fármaco. Previene muchas enfermedades…

Feb 7, 2021 · 11 shares · 5,148 followers View post →
Julio Rodríguez, PhD | Genética Clínica
@bitacorabeagle · X

El ejercicio es tan beneficioso para la salud que debería ser considerado como un fármaco. Previene muchas enfermedades y promueve una longevidad saludable. Puede considerarse como tratamiento de enfermedades cardiovasculares, depresión o diabetes. https://t.co/oX9Kpog28I https://t.co/ggbpfnbYd8

Feb 7, 2021 · 29 likes · 11 shares · 29,454 followers View post →
Dr. Ramon Reyes, MD
@eeiispain · X

El ejercicio es tan beneficioso para la salud que debería ser considerado como un fármaco. Previene muchas enfermedades y promueve una longevidad saludable. Puede considerarse como tratamiento de enfermedades cardiovasculares, depresión o diabetes. https://t.co/f3dw5lYZo6 https://t.co/PSkz1cd742

Feb 7, 2021 · 1 like · 1 share · 594 followers View post →
Terez
@Terez84577504 · X

Exercise acts as a drug; the pharmacological benefits of exercise https://t.co/TJSqDuXHuu

Oct 15, 2020 · 339 followers View post →
green heart
@br_green_heart · X

RT @abnelalecrim: @FredLAFernandes A ciência comprovou que o exercício é tão eficaz para regular e promover saúde que cura doenças. O exerc…

Sep 20, 2020 · 1 share · 3,358 followers View post →
Abnel Alecrim
@abnelalecrim · X

@FredLAFernandes A ciência comprovou que o exercício é tão eficaz para regular e promover saúde que cura doenças. O exercício age como uma droga e tem benefícios farmacológicos, e a atenção deve ser dada à dosagem e às variações individuais entre os pacientes. (https://t.co/1M3lxDZMHa)

Sep 20, 2020 · 2 likes · 1 share · 4,103 followers View post →
Abnel Alecrim
@abnelalecrim · X

A ciência comprovou que o exercício é tão eficaz para regular e promover saúde que cura doenças. O exercício age como uma droga e tem benefícios farmacológicos, e a atenção deve ser dada à dosagem e às variações individuais entre os pacientes. (https://t.co/1M3lxDZMHa)

Sep 20, 2020 · 4,103 followers View post →
MorozkoForge
@MorozkoForge · X

Is "exercise a drug" like this article suggests? Or, are drugs just poor attempts to mimic the benefits of exercise? https://t.co/fzNxkhGDZm

Jan 5, 2020 · 2 likes · 2,447 followers View post →
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