PubHawk
Cell April 2012 PMID 22500797

mTOR signaling in growth control and disease.

Mathieu Laplante, David M Sabatini

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Mentions

54
Peak: 6 in Nov 2022
across 5 sources since Mar 2019

Extended reach

121,901
potential audience

Total likes

1,410

Video views

43,010

Mentions per month

Mar 2019 – Oct 2024

Where it's discussed

  • News26 articles
  • X / Twitter10 posts
  • Facebook8 posts
  • Blogs8 articles
  • YouTube2 videos

AI synopsis

What people are saying

The digital discussions demonstrate strong interest and agreement, as users reference influential papers by Laplante & Sabatini and Johnson et al., emphasizing mTOR's central role in growth, aging, and disease. The tone suggests respect and curiosity, with phrases like 'hyperactivation may cause hyperglycemia' and 'mTOR is a key modulator,' reflecting acknowledgment of the pathway's potential for therapeutic targeting.

AgreementModerate agreement

Most discussion participants seem to concur that the research on mTOR is valuable for understanding disease mechanisms.

InterestHigh interest

The discussions reflect a high level of interest, referencing foundational studies and highlighting the pathway's significance.

EngagementModerate engagement

The posts show moderate engagement, with users reposting key articles and commenting on hypotheses related to mTOR's role.

ImpactModerate impact

Participants recognize that the research has meaningful implications for health and aging, indicating perceived high impact.

Abstract in brief

  • The mTOR signaling pathway is crucial for controlling growth and maintaining balance in the body by sensing environmental signals.
  • It governs many vital cellular processes and is linked to various diseases such as cancer, obesity, diabetes, and neurodegeneration.
  • The review highlights recent research on the mTOR pathway's role in health and aging, and explores potential drug treatments for conditions resulting from its dysregulation.]
Read the full abstract

Top posts

Most liked on X and Bluesky
Agingdoc
@agingdoc1 · X

mTOR Signaling in Growth Control and Disease (2010) @LaplanteMathieu @DMSabatini Repost h/t Mathieu

Nov 11, 2022 · 20 likes · 6 shares · 43,248 followers View post →
Nick Krontiris
@nick_krontiris · X

"Interestingly, as hypothesised by Laplante & Sabatini and others, hyperactivation as well as hypoactivation of mTOR is thought to be the cause for hyperglycemia... Refs: https://t.co/Zwc0Q0LODv https://t.co/cZJp2hHSlH

Jul 12, 2022 · 2 likes · 1 share · 19,466 followers View post →
IberianCitizen
@IberianCitizen · X

RT @nick_krontiris: "Interestingly, as hypothesised by Laplante & Sabatini and others, hyperactivation as well as hypoactivation of mTOR is…

Jul 12, 2022 · 1 share · 12,906 followers View post →
Jun-Liszt Li
@poppingjun · X

RT @agingdoc1: mTOR Signaling in Growth Control and Disease (2010) @LaplanteMathieu @DMSabatini Repost h/t Mathieu

Nov 12, 2022 · 6 shares · 1,036 followers View post →
Hasan Erdogan
@ProfDrHasanE · X

RT @agingdoc1: mTOR Signaling in Growth Control and Disease (2010) @LaplanteMathieu @DMSabatini Repost h/t Mathieu

Dec 3, 2022 · 6 shares · 669 followers View post →
BillOckham
@BillOccham0 · X

RT @agingdoc1: mTOR Signaling in Growth Control and Disease (2010) @LaplanteMathieu @DMSabatini Repost h/t Mathieu

Nov 11, 2022 · 6 shares · 574 followers View post →

All mentions

AJAY
@ajay_aroz · X

@dranuj_k 5. mTOR: Laplante, M., & Sabatini, D. M. (2012). "mTOR signaling in growth control and disease." Cell, 149(2), 274-293. Johnson, S. C., Rabinovitch, P. S., & Kaeberlein, M. (2013). "mTOR is a key modulator of ageing and age-related disease." Nature, 493(7432), 338-345.

Oct 8, 2024 · 33 followers View post →
Hasan Erdogan
@ProfDrHasanE · X

RT @agingdoc1: mTOR Signaling in Growth Control and Disease (2010) @LaplanteMathieu @DMSabatini Repost h/t Mathieu

Dec 3, 2022 · 6 shares · 669 followers View post →
SabineRing
@ring_sabine · X

RT @agingdoc1: mTOR Signaling in Growth Control and Disease (2010) @LaplanteMathieu @DMSabatini Repost h/t Mathieu

Nov 13, 2022 · 6 shares · 52 followers View post →
Dr. Lucks Lifestyle Med Health & Well-Being Prac.
@luckssj · X

RT @agingdoc1: mTOR Signaling in Growth Control and Disease (2010) @LaplanteMathieu @DMSabatini Repost h/t Mathieu

Nov 12, 2022 · 6 shares · 546 followers View post →
N. Moncada
@ChiguiMedicina · X

RT @agingdoc1: mTOR Signaling in Growth Control and Disease (2010) @LaplanteMathieu @DMSabatini Repost h/t Mathieu

Nov 12, 2022 · 6 shares · 274 followers View post →
Jun-Liszt Li
@poppingjun · X

RT @agingdoc1: mTOR Signaling in Growth Control and Disease (2010) @LaplanteMathieu @DMSabatini Repost h/t Mathieu

Nov 12, 2022 · 6 shares · 1,036 followers View post →
BillOckham
@BillOccham0 · X

RT @agingdoc1: mTOR Signaling in Growth Control and Disease (2010) @LaplanteMathieu @DMSabatini Repost h/t Mathieu

Nov 11, 2022 · 6 shares · 574 followers View post →
Agingdoc
@agingdoc1 · X

mTOR Signaling in Growth Control and Disease (2010) @LaplanteMathieu @DMSabatini Repost h/t Mathieu

Nov 11, 2022 · 20 likes · 6 shares · 43,248 followers View post →
IberianCitizen
@IberianCitizen · X

RT @nick_krontiris: "Interestingly, as hypothesised by Laplante & Sabatini and others, hyperactivation as well as hypoactivation of mTOR is…

Jul 12, 2022 · 1 share · 12,906 followers View post →
Nick Krontiris
@nick_krontiris · X

"Interestingly, as hypothesised by Laplante & Sabatini and others, hyperactivation as well as hypoactivation of mTOR is thought to be the cause for hyperglycemia... Refs: https://t.co/Zwc0Q0LODv https://t.co/cZJp2hHSlH

Jul 12, 2022 · 2 likes · 1 share · 19,466 followers View post →