June 2012 PMID 22608008

Time-restricted feeding without reducing caloric intake prevents metabolic diseases in mice fed a high-fat diet.

Megumi Hatori, Christopher Vollmers, Amir Zarrinpar, Luciano DiTacchio, Eric A Bushong, Shubhroz Gill, Mathias Leblanc, Amandine Chaix, Matthew Joens, James A J Fitzpatrick, Mark H Ellisman, Satchidananda Panda

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Mentions

279
Peak: 8 in Jun 2023
across 6 sources since Jan 2018

Extended reach

750,387
potential audience

Total likes

8,377

Video views

505,899

Mentions per month

Jan 2018 – Jul 2025

Where it's discussed

  • News168 articles
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  • YouTube7 videos
  • Reddit6 posts

AI synopsis

What people are saying

The discussions show strong interest and moderate engagement, with posts referencing the study’s relevance to human fasting practices and biological impacts, using terms like 'addresses your point' and 'biological impact' which highlight both curiosity and thoughtfulness about the research's significance.

AgreementModerate agreement

Most discussions support the findings that time-restricted feeding can prevent metabolic diseases without reducing calories, indicating general agreement with the research.

InterestHigh interest

Many discussion posts show high curiosity, referencing related topics like human studies, intermittent fasting, and biological impacts, highlighting strong interest.

EngagementModerate engagement

The posts often delve into explanations of methods, implications, and comparisons to other dietary patterns, reflecting a moderate level of thoughtful engagement.

ImpactModerate impact

While some recognize the significance of the research, many see it as part of ongoing dialogue about diet and health, suggesting a notable but not groundbreaking impact.

Abstract in brief

  • Timerestricted feeding (tRF) protects mice from obesity and metabolic diseases caused by a high-fat diet without reducing overall calorie intake, suggesting that meal timing is crucial.
  • tRF helps maintain normal metabolic cycles and improves the function of key signaling pathways like CREB, mTOR, and AMPK, which are involved in energy regulation and circadian rhythms.
  • The study indicates that aligning feeding patterns with natural biological rhythms can be an effective non-drug approach to prevent obesity and related health issues in mice.]

Top posts

Most liked on X and Bluesky
Ana Bonassa
@aAnaBonassa · X

https://t.co/10bk07rNzS https://t.co/iOBMdlTF4h https://t.co/FVKh0pONbK https://t.co/SWDHgOZcsG https://t.co/SLG6pQlsBj https://t.co/xVDgifoATG Pular o café da manhã: https://t.co/7jBigwcIT6 https://t.co/Ri3yoxaC1S https://t.co/8N9LWBKnCs https://t.co/hC3JNIzTvW

Jan 3, 2023 · 37 likes · 39,903 followers View post →
Agingdoc
@agingdoc1 · X

Time-restricted feeding without reducing caloric intake prevents metabolic diseases in mice fed a high-fat diet (2012) https://t.co/ophK8Be7xL https://t.co/d0HdiKTaPA

Feb 16, 2023 · 17 likes · 2 shares · 41,228 followers View post →
Agingdoc
@agingdoc1 · X

Time-Restricted Feeding without Reducing Caloric Intake Prevents Metabolic Diseases in Mice Fed a High-Fat Diet (2012) https://t.co/ophK8Be7xL @Cell_Metabolism https://t.co/xmeBILXkOz

Jun 13, 2023 · 13 likes · 6 shares · 41,228 followers View post →
Eleanor Sheekey
@EleanorSheekey · X

Intermittent fasting (dawn to sunset) human study; biological impact https://t.co/RSEwvqSE9C via @YouTube #biochemistry #scicomm

May 12, 2020 · 2 likes · 1 share · 4,869 followers View post →
Eleanor Sheekey
@EleanorSheekey · X

Made a mini-documentary style-vid on --> Why When We Eat Is So Important (the science explained) https://t.co/SF8NjohZr7 via @YouTube #intermittentfasting #biochemistry #scicomm

Jul 2, 2020 · 2 likes · 1 share · 4,869 followers View post →
Fez☯️
@Zenfrog4 · X

@PGC1a_RB this study yes - https://t.co/mQF7B4wRsT this study no - https://t.co/XfY4OA5j6t

Sep 15, 2024 · 2 likes · 3,102 followers View post →

All mentions

カクタス。
@ixitaka · X

摂食時間を活動期の8時間に制限する時間制限摂食(time-restricted feeding)を行ったマウスは、自由摂食させたマウスと同等のカロリーを高脂肪食から摂取しながらも、食事誘導性の肥満が抑制された。 https://t.co/ghbgXzOQVl

Jul 11, 2025 · 187 followers View post →
Fez☯️
@Zenfrog4 · X

@PGC1a_RB this study yes - https://t.co/mQF7B4wRsT this study no - https://t.co/XfY4OA5j6t

Sep 15, 2024 · 2 likes · 3,102 followers View post →
Fez☯️
@Zenfrog4 · X

https://t.co/mQF7B4wRsT

Sep 15, 2024 · 1 like · 3,102 followers View post →
EnhancerOfZeste
@Pumpkinowsky · X

@KirilJT Еве ти кај глувци. Погоре во твитовите имаш линк со детални студии. https://t.co/6UCKpjDuIU

Mar 23, 2024 · 2,721 followers View post →
Ᏼꭱꮎꮓꭼꮶ
@jonathanbrozek · X

Time restricted feeding without reducing caloric intake prevents metabolic diseases in mice fed a high fat diet https://t.co/1WL8WWRfXk

Aug 17, 2023 · 1,082 followers View post →
Jorge Guerrero, MD
@JorgeGuerreroMD · X

Jul 28, 2023 · 31 followers View post →
Jorge Guerrero, MD
@JorgeGuerreroMD · X

Jul 28, 2023 · 31 followers View post →
Jorge Guerrero, MD
@JorgeGuerreroMD · X

Jul 28, 2023 · 31 followers View post →
genomicspark
@hexomics · X

RT @agingdoc1: Time-Restricted Feeding without Reducing Caloric Intake Prevents Metabolic Diseases in Mice Fed a High-Fat Diet (2012) http…

Jun 14, 2023 · 6 shares · 91 followers View post →
Dieter
@Wuhle · X

RT @agingdoc1: Time-Restricted Feeding without Reducing Caloric Intake Prevents Metabolic Diseases in Mice Fed a High-Fat Diet (2012) http…

Jun 14, 2023 · 6 shares · 473 followers View post →
Thomas P Seager, PhD
@seagertp · X

RT @agingdoc1: Time-Restricted Feeding without Reducing Caloric Intake Prevents Metabolic Diseases in Mice Fed a High-Fat Diet (2012) http…

Jun 13, 2023 · 6 shares · 12,332 followers View post →
HomeTownLess
@HaizhenWang1 · X

RT @agingdoc1: Time-Restricted Feeding without Reducing Caloric Intake Prevents Metabolic Diseases in Mice Fed a High-Fat Diet (2012) http…

Jun 13, 2023 · 6 shares · 49 followers View post →
Agingdoc
@agingdoc1 · X

RT @agingdoc1: Time-Restricted Feeding without Reducing Caloric Intake Prevents Metabolic Diseases in Mice Fed a High-Fat Diet (2012) http…

Jun 13, 2023 · 6 shares · 41,228 followers View post →
GLASS_PhD
@joybeingfree99 · X

RT @agingdoc1: Time-Restricted Feeding without Reducing Caloric Intake Prevents Metabolic Diseases in Mice Fed a High-Fat Diet (2012) http…

Jun 13, 2023 · 6 shares · 6,646 followers View post →
Agingdoc
@agingdoc1 · X

Time-Restricted Feeding without Reducing Caloric Intake Prevents Metabolic Diseases in Mice Fed a High-Fat Diet (2012) https://t.co/ophK8Be7xL @Cell_Metabolism https://t.co/xmeBILXkOz

Jun 13, 2023 · 13 likes · 6 shares · 41,228 followers View post →
Luiz Romeiro
@lasromeiro · X

RT @agingdoc1: Time-restricted feeding without reducing caloric intake prevents metabolic diseases in mice fed a high-fat diet (2012) http…

Feb 17, 2023 · 2 shares · 183 followers View post →
Dr. Shashank Joshi
@AskDrShashank · X

RT @agingdoc1: Time-restricted feeding without reducing caloric intake prevents metabolic diseases in mice fed a high-fat diet (2012) http…

Feb 16, 2023 · 2 shares · 32,538 followers View post →
Agingdoc
@agingdoc1 · X

Time-restricted feeding without reducing caloric intake prevents metabolic diseases in mice fed a high-fat diet (2012) https://t.co/ophK8Be7xL https://t.co/d0HdiKTaPA

Feb 16, 2023 · 17 likes · 2 shares · 41,228 followers View post →
Ana Bonassa
@aAnaBonassa · X

https://t.co/10bk07rNzS https://t.co/iOBMdlTF4h https://t.co/FVKh0pONbK https://t.co/SWDHgOZcsG https://t.co/SLG6pQlsBj https://t.co/xVDgifoATG Pular o café da manhã: https://t.co/7jBigwcIT6 https://t.co/Ri3yoxaC1S https://t.co/8N9LWBKnCs https://t.co/hC3JNIzTvW

Jan 3, 2023 · 37 likes · 39,903 followers View post →
Korey Kasper
@KoreyKasper · X

Time-Restricted Feeding without Reducing Caloric Intake Prevents Metabolic Diseases in Mice Fed a High-Fat Diet: Cell Metabolism https://t.co/LB9EK3QxWs

Sep 27, 2022 · 71 followers View post →
豆乳ヨーグルトのプロバイオ
@Probio_ASO · X

#朝の論文紹介 https://t.co/oEMFiVOS1f 高脂肪食をマウスに与え、エサを自由に摂取できる群と摂取の時間を制限したマウスを比較⌚ 同じカロリーを摂取した場合でも、食べる時間を制限したマウスでは ・体重の増加抑制 ・胆汁酸の産生量増加 ・エネルギー消費の改善 ・炎症の軽減   などが報告 https://t.co/hLrvBV1d6I

Dec 21, 2021 · 2 likes · 166 followers View post →
Dario Riccardo Valenzano
@dariovalenzano_ · X

@MariaErmolaev13 This paper by Satchidananda Panda's group addresses your very point: https://t.co/KJ1Qr5C6fa

Oct 19, 2021 · 2 likes · 2,500 followers View post →
Gohsuke Takama
@gohsuket · X

|・ω・`)フムフム similar eating schedule as Ramadan "Intermittent fasting (dawn to sunset) human study; biological impact" on YouTube - https://t.co/EbEnQ1bATu

Aug 26, 2021 · 2,992 followers View post →
Runcibald Spooner
@everburningfire · X

RT @EleanorSheekey: Made a mini-documentary style-vid on --> Why When We Eat Is So Important (the science explained) https://t.co/SF8NjohZ…

Jul 2, 2020 · 1 share · 675 followers View post →
Eleanor Sheekey
@EleanorSheekey · X

Made a mini-documentary style-vid on --> Why When We Eat Is So Important (the science explained) https://t.co/SF8NjohZr7 via @YouTube #intermittentfasting #biochemistry #scicomm

Jul 2, 2020 · 2 likes · 1 share · 4,869 followers View post →
睡眠良くしたければケトジェニック!(低糖質&高脂質)|小林充典|睡眠歯科医療3000人・減量指導
@tolucky39 · X

参考文献 食事の時間を制限したマウスは高脂肪食を摂取しても肥満やメタボリックシンドロームにならない Time-restricted feeding without reducing caloric intake prevents metabolic diseases in mice fed a high-fat diet. https://t.co/6vQ9dV3W3C https://t.co/cjSVmngc0x

May 22, 2020 · 1,083 followers View post →
Runcibald Spooner
@everburningfire · X

RT @EleanorSheekey: Intermittent fasting (dawn to sunset) human study; biological impact https://t.co/RSEwvqSE9C via @YouTube #biochemistry…

May 12, 2020 · 1 share · 675 followers View post →
Eleanor Sheekey
@EleanorSheekey · X

Intermittent fasting (dawn to sunset) human study; biological impact https://t.co/RSEwvqSE9C via @YouTube #biochemistry #scicomm

May 12, 2020 · 2 likes · 1 share · 4,869 followers View post →
laili
@laili_lai · X

Time-restricted feeding without reducing caloric intake prevents metabolic diseases in mice fed a high-fat diet. - PubMed - NCBI https://t.co/HQE99YJkXB

Jul 24, 2019 · 67 followers View post →
testnetエアドロ
@morekirekan · X

Time-restricted feeding without reducing caloric intake prevents metabolic diseases in mice fed a high-fat diet.という論文を和訳してくれてる↓ まとめ ・マウスで高脂肪食を同量、1日中食べられる群と8時間に制限された群にわけたら時間制限群はメタボらなかった https://t.co/UH5xCZeNbN

Jun 6, 2019 · 2 likes · 233 followers View post →