Role of dopamine receptors in ADHD: a systematic meta-analysis.

Jing Wu, Haifan Xiao, Hongjuan Sun, Li Zou, Ling-Qiang Zhu

June 2012 Mol Neurobiol

Synopsis of Social media discussions

The discussions show a clear interest in the genetic and neurochemical factors of ADHD, with comments referencing recent research, the dopamine hypothesis, and its implications for diagnosis and treatment. The tone and language reflect curiosity and acknowledgment of ongoing scientific debates, indicating active engagement and recognition of the subject’s significance.

A
Agreement
 Moderate agreement

Most discussions support the research's relevance, highlighting the genetic and neurochemical aspects of ADHD.

I
Interest
 High level of interest

The social discussions demonstrate high curiosity, especially about dopamine's role and treatment implications.

E
Engagement
 Moderate level of engagement

Participants reference specific studies, theories, and personal experiences, indicating moderate depth of engagement.

I
Impact
 Moderate level of impact

The discourse emphasizes the importance of understanding dopamine receptors for diagnosis and treatment, suggesting a mild perceived impact.

Social Mentions

YouTube

2 Videos

Bluesky

1 Posts

Twitter

7 Posts

Blogs

3 Articles

News

22 Articles

Metrics

Video Views

13,413

Total Likes

352

Extended Reach

72,781

Social Features

35

Timeline: Posts about article

Top Social Media Posts

Posts referencing the article

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  • Jade Whirl
    @jadewhirl.bsky.social (Bluesky)

    Aerf Elle est derrière un paywall désolée, j'ai profité de mon ancien employeur pour l'abonnement -_- C'est Wu, J., Xiao, H., Sun, H. et al. Role of Dopamine Receptors in ADHD: A Systematic Meta-analysis. Mol Neurobiol 45, 605–620 (2012).
    view full post

    January 23, 2025

    7

    2

  • Áshkán
    @Itwasfuniguess (Twitter)

    @Kavehism @dayakhamesiDK @ihoomawn کلا ADHD خیلی Multifactorial هستش. یعنی شما یه طیف بزرگی از عوامل ژنتیکی و محیطی رو باید ببینی. چه بحث وراثت و چه بحث تراپی. https://t.co/BCY4KUjqcX https://t.co/caew7Ctc5Y https://t.co/t0vqa9McW6 https://t.co/fzhJUVP82M https://t.co/rH8fEpgORs https://t.co/3Fe7ac9WTk https://t.co/NQukXIiih4
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    March 10, 2024

    1

  • Douglas Turner
    @mkedgt2 (Twitter)

    @coopercdavis @MarkLRuffalo I had to look it up again, it has been a while since my doctor and I discussed it. The best takeaway is to understand that the difference is why using a stimulant is the best diagnostic tool, ADHD people react differently. https://t.co/dVJ1fUIUkf
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    February 19, 2024

    1

  • Alex
    @alex_hagle (Twitter)

    RT @StructuredSucc: @SNeurotypicals The dopamine hypothesis is one potential explanation for ADHD, but I don't believe there is a concrete…
    view full post

    September 29, 2021

    2

  • Ghilan’nain’s Creature
    @flowersofmetal (Twitter)

    RT @StructuredSucc: @SNeurotypicals The dopamine hypothesis is one potential explanation for ADHD, but I don't believe there is a concrete…
    view full post

    September 28, 2021

    2

  • Structured Success
    @StructuredSucc (Twitter)

    @SNeurotypicals The dopamine hypothesis is one potential explanation for ADHD, but I don't believe there is a concrete mechanism identified yet. What we do know is that dopamine receptors are implicated: https://t.co/x7XmHrtKuR
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    September 28, 2021

    28

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  • ProbablyCIA
    @shireen_noroozi (Twitter)

    @anthonyzenkus @TheJniac @JaneWeb73307136 @BernieToVest dopamine's a neurotransmitter. So it needs to find a receptor in order to relay its "message." Usually people inherit ADHD through genes. There's been new studies identifying these genes. ADHD is literally as structural as being left or right-handed. https://t.co/HEp9sU6Vzz
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    April 5, 2021

    1

  • Reut Avinun, PhD
    @AvinunReut (Twitter)

    @WiringTheBrain I think that a 2008 meta analysis did find some sort of an association https://t.co/2fC1rIYqEt And the link with ADHD has also been shown in meta analyses https://t.co/jeqpTTxZQn and https://t.co/AuNMmXAvA3
    view full post

    March 23, 2019

Abstract Synopsis

  • The dopaminergic system, which involves five dopamine receptors (D1-D5), is crucial in the brain, and its dysfunction is linked to neuropsychological disorders like ADHD.
  • This systematic review and meta-analysis focus on how genetic variations (polymorphisms) in dopamine receptor genes, especially DRD5, DRD2, and DRD4, are associated with an increased risk of developing ADHD.
  • Understanding the specific roles of these dopamine receptors can help in developing targeted treatments for ADHD by clarifying their involvement in the disorder's pathogenesis.]