Mol Neurobiol June 2012 PMID 22610946

Role of dopamine receptors in ADHD: a systematic meta-analysis.

Jing Wu, Haifan Xiao, Hongjuan Sun, Li Zou, Ling-Qiang Zhu

Mentions

35
Peak: 3 in Sep 2021
across 5 sources since Mar 2019

Extended reach

72,781
potential audience

Total likes

352

Video views

13,413

Mentions per month

Mar 2019 – Jan 2025

Where it's discussed

  • News22 articles
  • X / Twitter7 posts
  • Blogs3 articles
  • YouTube2 videos
  • Bluesky1 posts

AI synopsis

What people are saying

The discussions show a clear interest in the genetic and neurochemical factors of ADHD, with comments referencing recent research, the dopamine hypothesis, and its implications for diagnosis and treatment. The tone and language reflect curiosity and acknowledgment of ongoing scientific debates, indicating active engagement and recognition of the subject’s significance.

AgreementModerate agreement

Most discussions support the research's relevance, highlighting the genetic and neurochemical aspects of ADHD.

InterestHigh interest

The social discussions demonstrate high curiosity, especially about dopamine's role and treatment implications.

EngagementModerate engagement

Participants reference specific studies, theories, and personal experiences, indicating moderate depth of engagement.

ImpactModerate impact

The discourse emphasizes the importance of understanding dopamine receptors for diagnosis and treatment, suggesting a mild perceived impact.

Abstract in brief

  • The dopaminergic system, which involves five dopamine receptors (D1-D5), is crucial in the brain, and its dysfunction is linked to neuropsychological disorders like ADHD.
  • This systematic review and meta-analysis focus on how genetic variations (polymorphisms) in dopamine receptor genes, especially DRD5, DRD2, and DRD4, are associated with an increased risk of developing ADHD.
  • Understanding the specific roles of these dopamine receptors can help in developing targeted treatments for ADHD by clarifying their involvement in the disorder's pathogenesis.]

Top posts

Most liked on X and Bluesky
Structured Success
@StructuredSucc · X

@SNeurotypicals The dopamine hypothesis is one potential explanation for ADHD, but I don't believe there is a concrete mechanism identified yet. What we do know is that dopamine receptors are implicated: https://t.co/x7XmHrtKuR

Sep 28, 2021 · 28 likes · 2 shares · 55,385 followers View post →
Jade Whirl
@jadewhirl.bsky.social · Bluesky

Aerf Elle est derrière un paywall désolée, j'ai profité de mon ancien employeur pour l'abonnement -_- C'est Wu, J., Xiao, H., Sun, H. et al. Role of Dopamine Receptors in ADHD: A Systematic Meta-analysis. Mol Neurobiol 45, 605–620 (2012).

Jan 23, 2025 · 7 likes · 2 shares View post →
Douglas Turner
@mkedgt2 · X

@coopercdavis @MarkLRuffalo I had to look it up again, it has been a while since my doctor and I discussed it. The best takeaway is to understand that the difference is why using a stimulant is the best diagnostic tool, ADHD people react differently. https://t.co/dVJ1fUIUkf

Feb 19, 2024 · 1 like · 2,505 followers View post →
ProbablyCIA
@shireen_noroozi · X

@anthonyzenkus @TheJniac @JaneWeb73307136 @BernieToVest dopamine's a neurotransmitter. So it needs to find a receptor in order to relay its "message." Usually people inherit ADHD through genes. There's been new studies identifying these genes. ADHD is literally as structural as being left or right-handed. https://t.co/HEp9sU6Vzz

Apr 5, 2021 · 1 like · 315 followers View post →
Áshkán
@Itwasfuniguess · X

@Kavehism @dayakhamesiDK @ihoomawn کلا ADHD خیلی Multifactorial هستش. یعنی شما یه طیف بزرگی از عوامل ژنتیکی و محیطی رو باید ببینی. چه بحث وراثت و چه بحث تراپی. https://t.co/BCY4KUjqcX https://t.co/caew7Ctc5Y https://t.co/t0vqa9McW6 https://t.co/fzhJUVP82M https://t.co/rH8fEpgORs https://t.co/3Fe7ac9WTk https://t.co/NQukXIiih4

Mar 10, 2024 · 1 like · 117 followers View post →
Ghilan’nain’s Creature
@flowersofmetal · X

RT @StructuredSucc: @SNeurotypicals The dopamine hypothesis is one potential explanation for ADHD, but I don't believe there is a concrete…

Sep 28, 2021 · 2 shares · 521 followers View post →

All mentions

Jade Whirl
@jadewhirl.bsky.social · Bluesky

Aerf Elle est derrière un paywall désolée, j'ai profité de mon ancien employeur pour l'abonnement -_- C'est Wu, J., Xiao, H., Sun, H. et al. Role of Dopamine Receptors in ADHD: A Systematic Meta-analysis. Mol Neurobiol 45, 605–620 (2012).

Jan 23, 2025 · 7 likes · 2 shares View post →
Áshkán
@Itwasfuniguess · X

@Kavehism @dayakhamesiDK @ihoomawn کلا ADHD خیلی Multifactorial هستش. یعنی شما یه طیف بزرگی از عوامل ژنتیکی و محیطی رو باید ببینی. چه بحث وراثت و چه بحث تراپی. https://t.co/BCY4KUjqcX https://t.co/caew7Ctc5Y https://t.co/t0vqa9McW6 https://t.co/fzhJUVP82M https://t.co/rH8fEpgORs https://t.co/3Fe7ac9WTk https://t.co/NQukXIiih4

Mar 10, 2024 · 1 like · 117 followers View post →
Douglas Turner
@mkedgt2 · X

@coopercdavis @MarkLRuffalo I had to look it up again, it has been a while since my doctor and I discussed it. The best takeaway is to understand that the difference is why using a stimulant is the best diagnostic tool, ADHD people react differently. https://t.co/dVJ1fUIUkf

Feb 19, 2024 · 1 like · 2,505 followers View post →
Alex
@alex_hagle · X

RT @StructuredSucc: @SNeurotypicals The dopamine hypothesis is one potential explanation for ADHD, but I don't believe there is a concrete…

Sep 29, 2021 · 2 shares · 225 followers View post →
Ghilan’nain’s Creature
@flowersofmetal · X

RT @StructuredSucc: @SNeurotypicals The dopamine hypothesis is one potential explanation for ADHD, but I don't believe there is a concrete…

Sep 28, 2021 · 2 shares · 521 followers View post →
Structured Success
@StructuredSucc · X

@SNeurotypicals The dopamine hypothesis is one potential explanation for ADHD, but I don't believe there is a concrete mechanism identified yet. What we do know is that dopamine receptors are implicated: https://t.co/x7XmHrtKuR

Sep 28, 2021 · 28 likes · 2 shares · 55,385 followers View post →
ProbablyCIA
@shireen_noroozi · X

@anthonyzenkus @TheJniac @JaneWeb73307136 @BernieToVest dopamine's a neurotransmitter. So it needs to find a receptor in order to relay its "message." Usually people inherit ADHD through genes. There's been new studies identifying these genes. ADHD is literally as structural as being left or right-handed. https://t.co/HEp9sU6Vzz

Apr 5, 2021 · 1 like · 315 followers View post →
Reut Avinun, PhD
@AvinunReut · X

@WiringTheBrain I think that a 2008 meta analysis did find some sort of an association https://t.co/2fC1rIYqEt And the link with ADHD has also been shown in meta analyses https://t.co/jeqpTTxZQn and https://t.co/AuNMmXAvA3

Mar 23, 2019 · 284 followers View post →