PLoS One September 2012 PMID 22616011

Mapping connectivity damage in the case of Phineas Gage.

John Darrell Van Horn, Andrei Irimia, Carinna M Torgerson, Micah C Chambers, Ron Kikinis, Arthur W Toga

Download social card

Mentions

104

Peak: 1 in Jun 2019

across 6 sources since Jun 2019

Extended reach

35,258

potential audience

Total likes

696

Video views

10,715

Mentions per month

Jun 2019 – Sep 2025

Where it's discussed

News54 articles
Facebook21 posts
Blogs18 articles
X / Twitter6 posts
YouTube3 videos
Reddit2 posts

AI synopsis

What people are saying

The discussions highlight the article's significance through expressions like 'mapping connectivity damage' and mention of advanced brain imaging techniques, emphasizing the importance of the study for neurotrauma understanding. The tone reflects curiosity and recognition of potential clinical impact, driven by technical references and appreciation for the research’s innovative approach.

AgreementModerate agreement

Most discussions recognize the significance of the research, reflecting general agreement on its importance for understanding brain injury effects.

InterestHigh interest

Posts express high curiosity, with many referencing the innovative imaging techniques and new insights into brain connectivity after injury.

EngagementModerate engagement

Several contributions delve into methodology and the broader implications, showing moderate depth of engagement.

ImpactModerate impact

Discussions suggest that this research could influence neurotrauma studies and clinical approaches, though the broad impact remains somewhat aspirational.

Abstract in brief

The study uses advanced brain imaging techniques and simulations to analyze the white matter damage in Phineas Gage's brain after his famous injury, focusing on how this damage influenced brain connectivity and behavior.
The research found that although there was significant localized damage to the left frontal cortex, the injury also caused widespread disruptions in brain networks, which likely contributed to behavioral changes observed in Gage.
Despite the severity, the extent of Gage’s white matter damage was comparable to that of similar-sized brain injuries, offering new insights into how network-level brain damage impacts function following traumatic brain injury.]

Read the full abstract