Globus pharyngeus: a review of its etiology, diagnosis and treatment.

Abstract in brief

• Globus pharyngeus is a common, long-lasting condition characterized by a sensation of a lump in the throat, with unclear causes and challenging treatment options.
• Initial management involves careful patient history and nasal-laryngoscopy, and empirical treatment with high-dose proton pump inhibitors may be effective if reflux is suspected.
• For persistent symptoms, additional diagnostics like endoscopy, pH monitoring, and manometry are recommended, along with therapies such as speech therapy, antidepressants, and cognitive-behavioral therapy if needed.